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Type 'q()' to quit R. > > library("tram") Loading required package: mlt Loading required package: basefun Loading required package: variables Loading required package: mvtnorm > library("sandwich") > library("survival") > library("numDeriv") > > ### scores for fixed parameters > cars$int <- 1 > a0 <- Lm(dist ~ speed, data = cars) > a1 <- Lm(dist ~ speed + int, data = cars, fixed = c("int" = 0)) > > s0 <- estfun(a0) > s1 <- estfun(a1) > s2 <- estfun(a1, parm = coef(as.mlt(a1), fixed = TRUE)) > > stopifnot(all.equal(s0[,"(Intercept)"], -s2[,"int"])) > stopifnot(all.equal(s1[,"(Intercept)"], -s2[,"int"])) > stopifnot(all.equal(s2[,"(Intercept)"], -s2[,"int"])) > > ### log_first for count data (by Sandra Siegfried) > ### use: y + 1; log_first = TRUE, support = c(1, ...), bounds = c(1, ...) > library("MASS") > set.seed(29) > Nsim <- 100 > b1 <- - 4.5 > b0 <- 5 > theta <- 2 > h <- qlogis(ppois(0:100, lambda = 5)) > dgp <- function(n = 4000){ + x <- runif(n, min = 0, max = 1) + log.mu <- b0 + b1 * x + h.m <- matrix(h, nrow = length(h), ncol = length(x)) + p <- (plogis(t(h.m) - b1 * x) - runif(n))^2 + y <- max.col(-p) - 1 + m <- Colr(y ~ x, data = data.frame(y = y, x = x), + bounds = c(0L, Inf), fixed = c("x" = -b1), + support = c(0L, floor(quantile(y, .9))), order = 10) + + ret <- data.frame(x = x, y = as.integer(y)) + attr(ret, "mC") <- m + ret + } > d <- dgp() > d$y.p1 <- d$y + 1L > > m1 <- Colr(y ~ x, data = d, + support = c(0L, as.numeric(max(d$y))), + bounds = c(0L, Inf), + order = 10) > > try(m2a <- Colr(y ~ x, data = d, + support = c(1L, as.numeric(max(d$y))), + bounds = c(1L, Inf), + log_first = TRUE, + order = 10)) Error in mlt(model = structure(list(model = structure(list(bresponse = structure(function (data, : check(responsevar, data) is not TRUE > > try(m2b <- Colr(y ~ x, data = d, + support = c(1L, as.numeric(max(d$y))), + bounds = c(0L, Inf), + log_first = TRUE, + order = 10)) Error in mlt(model = structure(list(model = structure(list(bresponse = structure(function (data, : check(responsevar, data) is not TRUE > > m3 <- Colr(y.p1 ~ x, data = d, + support = c(1L, as.numeric(max(d$y.p1))), + bounds = c(1L, Inf), + log_first = TRUE, + order = 10) > > l1 <- m1$logliki(coef(as.mlt(m1)), rep(1, nrow(d))) > l3 <- m3$logliki(coef(as.mlt(m3)), rep(1, nrow(d))) > stopifnot(cor(l1, l3) > .96) > > ### normal CDF approximation by Matic et al (2018) > x <- -600:600 / 100 > p1 <- .Call("R_pnormMRS", x) > p2 <- pnorm(x) > stopifnot(max(abs(p1 - p2)) < 5.79e-6) ### max absolute error > > ### 0.3-0 > data("GBSG2", package = "TH.data") > ### this model included an additional intercept > m1 <- Coxph(Surv(time, cens) | menostat:tgrade ~ horTh, data = GBSG2) > m2 <- Coxph(Surv(time, cens) | 0 + menostat:tgrade ~ horTh, data = GBSG2) > stopifnot(max(abs(coef(as.mlt(m1)) - coef(as.mlt(m2)))) < + sqrt(.Machine$double.eps)) > ### interaction term with stratum > m3 <- Coxph(Surv(time, cens) | horTh ~ menostat + menostat:horTh, + data = GBSG2) > ci <- confint(m3)["menostatPre:horThyes",] > stopifnot(all(!is.finite(ci))) > > ### problems with responses of class "R", spotted by Balint Tamasi > data("wine", package = "ordinal") > erating <- wine$rating > lrating <- erating > rrating <- erating > l9 <- lrating[wine$judge == 9] > l9[l9 > 1] <- levels(l9)[unclass(l9[l9 > 1]) - 1] > r9 <- rrating[wine$judge == 9] > r9[r9 < 5] <- levels(r9)[unclass(r9[r9 < 5]) + 1] > lrating[wine$judge != 9] <- rrating[wine$judge != 9] <- NA > erating[wine$judge == 9] <- NA > lrating[wine$judge == 9] <- l9 > rrating[wine$judge == 9] <- r9 > which(wine$judge == 9) [1] 65 66 67 68 69 70 71 72 > wine$crating <- R(erating, cleft = lrating, cright = rrating) > ### gave an error > m <- Polr(crating ~ temp, data = wine, method = "probit") > > ### another one > data("GBSG2", package = "TH.data") > tmp <- GBSG2 > tmp$y <- R(with(GBSG2, Surv(time, cens))) > m1 <- Coxph(Surv(time, cens) ~ horTh, data = tmp) > m2 <- Coxph(y ~ horTh, data = tmp) > stopifnot(all.equal(coef(as.mlt(m1)), coef(as.mlt(m2)), + check.attributes = FALSE)) > > ### check probabilistic index <-> log-odds ratio conversion > stopifnot(max(abs(PI(prob = PI(-15:15)) - (-15:15))) < 1e5) > > ### check updating with permutations > data("BostonHousing2", package = "mlbench") > m <- Colr(Surv(cmedv, cmedv < 50) ~ chas + crim, data = BostonHousing2) > mm <- as.mlt(m) > p <- sample(1:NROW(BostonHousing2)) > ## model with crim permuted > m1 <- update(mm, perm = "crim", permutation = p) > ## permute data directly > tmp <- BostonHousing2 > tmp[, "crim"] <- tmp[p, "crim"] > m2 <- Colr(Surv(cmedv, cmedv < 50) ~ chas + crim, data = tmp) > stopifnot(all.equal(coef(m1), coef(as.mlt(m2)), tol = 1e-3)) > stopifnot(all.equal(logLik(m1), logLik(m2), tol = 1e-6)) > > ### contraints, by Lucas Kook > data("GBSG2", package = "TH.data") > # gave an error > m <- Survreg(Surv(time, cens) ~ horTh + age, data = GBSG2, constraints = c("age >= 0")) > > ### mtram with interval censoring, spotted by Sandra Siegfried > dir <- system.file("rda", package = "TH.data") > load(file.path(dir, "Primary_endpoint_data.rda")) > trt <- "randarm5-FU + Oxaliplatin" > ### convert "exact" event dates to interval-censoring (+/- one day) > tmp <- CAOsurv$iDFS > exact <- tmp[,3] == 1 > tmp[exact,2] <- tmp[exact,1] + 2 > tmp[exact,1] <- pmax(tmp[exact,1] - 2, 0) > tmp[exact,3] <- 3 > CAOsurv$iDFS2 <- tmp > CAO_SR <- Survreg(iDFS2 ~ randarm, data = CAOsurv, support = c(1, 1700), bounds = c(0, Inf)) > CAO_SR_mtram <- mtram(CAO_SR, ~ (1 | Block), data = CAOsurv) > CAO_Cox <- Coxph(iDFS2 ~ randarm, data = CAOsurv, support = c(1, 1700), bounds = c(0, Inf), log_first = TRUE, order = 1) > CAO_Cox_mtram <- mtram(CAO_Cox, ~ (1 | Block), data = CAOsurv) > ### wasn't equal > stopifnot(isTRUE(all.equal(logLik(CAO_SR_mtram), logLik(CAO_Cox_mtram), tol = 1e-5))) > > ## produces negative variances in shift-scale model > set.seed(100) > N <- 100 > sc <- -5.5 > sh <- 3 > > FZ <- pnorm > FZi <- qnorm > h2y <- function(y) log(-FZ(y, lower.tail = FALSE, log.p = TRUE)) > > x <- rep(x0 <- gl(2, 1), each = N) > xx <- (0:1)[x] > > U <- runif(length(x)) > scale <- sqrt(exp(sc * xx)) > shift <- sh * xx > d <- data.frame(y = h2y( shift + FZi(U) / scale), + x = x) > m <- BoxCox(y ~ x | x, data = d, scale_shift = TRUE) > coef(m) x2 scl_x2 -4.562880 -5.168216 > try(diag(vcov(m))) Error in vcov.mlt(as.mlt(object)) : Hessian is not invertible > > ### constraints in remove intercept were incorrect > ### spotted by Balint > stopifnot(isTRUE(all.equal( + coef(as.mlt(Lm(dist ~ 1, data = cars, remove_intercept = FALSE)))[2:1] * c(-1, 1), + coef(as.mlt(Lm(dist ~ 1, data = cars))), check.attributes = FALSE))) > stopifnot(isTRUE(all.equal( + coef(as.mlt(Survreg(dist ~ 1, data = cars, remove_intercept = FALSE)))[2:1] * c(-1, 1), + coef(as.mlt(Survreg(dist ~ 1, data = cars))), check.attributes = FALSE))) > > ### mmlt with shift-scale had incorrect gradients > m1 <- Lm(Sepal.Width ~ Petal.Length | Petal.Width, data = iris) > m2 <- Lm(Sepal.Length ~ Petal.Length | Petal.Width, data = iris) > m0 <- mmlt(m1, m2, data = iris, formula = ~ 1, domargins = FALSE) > cf <- coef(m0) > m <- mmlt(m1, m2, data = iris, formula = ~ 1, dofit = FALSE) > stopifnot(isTRUE(all.equal(c(m$score(cf)), c(grad(m$ll, cf)), check.attributes = FALSE))) > > m1 <- Lm(Sepal.Width ~ Petal.Length | Petal.Width, data = iris, scale_shift = TRUE) > m2 <- Lm(Sepal.Length ~ Petal.Length | Petal.Width, data = iris, scale_shift = TRUE) > m0 <- mmlt(m1, m2, data = iris, formula = ~ 1, domargins = FALSE) > cf <- coef(m0) > m <- mmlt(m1, m2, data = iris, formula = ~ 1, dofit = FALSE) > stopifnot(isTRUE(all.equal(c(m$score(cf)), c(grad(m$ll, cf)), check.attributes = FALSE))) > > > proc.time() user system elapsed 38.81 5.40 44.21