R Under development (unstable) (2024-01-29 r85841 ucrt) -- "Unsuffered Consequences"
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> library(rxode2)
rxode2 2.1.2 using 2 threads (see ?getRxThreads)
  no cache: create with `rxCreateCache()`
> library(testthat)
> setRxThreads(1L)
> library(data.table)
> setDTthreads(1L)
> ##test_check("rxode2", reporter = testthat::LocationReporter)
> test_check("rxode2")
using C compiler: 'gcc.exe (GCC) 12.3.0'


using C compiler: 'gcc.exe (GCC) 12.3.0'


using C compiler: 'gcc.exe (GCC) 12.3.0'


using C compiler: 'gcc.exe (GCC) 12.3.0'


using C compiler: 'gcc.exe (GCC) 12.3.0'


using C compiler: 'gcc.exe (GCC) 12.3.0'


udunits database from D:/RCompile/CRANpkg/lib/4.4/units/share/udunits/udunits2.xml
using C compiler: 'gcc.exe (GCC) 12.3.0'


using C compiler: 'gcc.exe (GCC) 12.3.0'


using C compiler: 'gcc.exe (GCC) 12.3.0'


using C compiler: 'gcc.exe (GCC) 12.3.0'


using C compiler: 'gcc.exe (GCC) 12.3.0'


! in order to put confidence bands around the intervals, you need at least 2500 simulations
summarizing data...done
! in order to put confidence bands around the intervals, you need at least 2500 simulations
summarizing data...done
! in order to put confidence bands around the intervals, you need at least 2500 simulations
summarizing data...done
! in order to put confidence bands around the intervals, you need at least 2500 simulations
summarizing data...done
! in order to put confidence bands around the intervals, you need at least 2500 simulations
summarizing data...done
! in order to put confidence bands around the intervals, you need at least 2500 simulations
summarizing data...done
using C compiler: 'gcc.exe (GCC) 12.3.0'


i parameter labels from comments will be replaced by 'label()'
i add covariate `wt_cl`
i add covariate `WT`
i promote `wt_cl` to population parameter with initial estimate 0.75
i fix `wt_cl` to `0.75`
i change initial estimate of `wt_cl` to `0.75`
using C compiler: 'gcc.exe (GCC) 12.3.0'


using C compiler: 'gcc.exe (GCC) 12.3.0'


using C compiler: 'gcc.exe (GCC) 12.3.0'


i change initial estimate of `b` to `1`
i change initial estimate of `h` to `1`
i change initial estimate of `h` to `3`
i convert 'lka' from population parameter to between subject variability
i convert 'lka' from between subject variability to population parameter
i convert 'lka' from between subject variability to population parameter
i convert 'lka' from between subject variability to population parameter
i convert 'lcl' from population parameter to between subject variability
i old initial estimate was negative, changing to positive
i convert 'lvc' from population parameter to between subject variability
i old initial estimate is zero, changing to 1
i convert 'lvc' from between subject variability to population parameter
i convert 'lvc' from population parameter to between subject variability
i changing between subject variability parameter 'lka' to covariate parameter
i changing between subject variability parameter 'lka' to covariate parameter
using C compiler: 'gcc.exe (GCC) 12.3.0'


using C compiler: 'gcc.exe (GCC) 12.3.0'


using C compiler: 'gcc.exe (GCC) 12.3.0'


using C compiler: 'gcc.exe (GCC) 12.3.0'


> significant model change detected
> kept in model: '$matt'
> removed from model: '$f'
> significant model change detected
> kept in model: '$matt'
> removed from model: '$f'
i fix `tka` to `0.451075619360217`
i change initial estimate of `tcl` to `77`
> significant model change detected
> kept in model: '$matt'
> removed from model: '$f'
> significant model change detected
> kept in model: '$matt'
> removed from model: '$f'
i parameter labels from comments will be replaced by 'label()'
using C compiler: 'gcc.exe (GCC) 12.3.0'


i parameter labels from comments are typically ignored in non-interactive mode
i Need to run with the source intact to parse comments
i parameter labels from comments will be replaced by 'label()'
using C compiler: 'gcc.exe (GCC) 12.3.0'


using C compiler: 'gcc.exe (GCC) 12.3.0'


i promote `tvcl` to population parameter with initial estimate 1
i promote `tvcl` to population parameter with initial estimate 1
i promote `tvcl` to population parameter with initial estimate 1
i ignoring following estimates in 'm1': tka, eta.ka
i the labels from the piped model do not overwrite old labels
to change use 'options(rxode2.ignoreLabels=FALSE)'
i the labels from the piped model do not overwrite old labels
to change use 'options(rxode2.ignoreLabels=FALSE)'
i ignoring following estimates in 'm4': eta..cl, eta..v
i the labels from the piped model do not overwrite old labels
to change use 'options(rxode2.ignoreLabels=FALSE)'
i ignoring following estimates in 'm1': tka, eta.ka, eta.cl, eta.v
i the labels from the piped model do not overwrite old labels
to change use 'options(rxode2.ignoreLabels=FALSE)'
i ignoring following estimates in 'm5': t.cl, t.v, add..sd
i ignoring following estimates in 'm1': tka, tcl, tv, add.sd, eta.ka
i piping 'm6' has no parameters in common with model and does nothing
i piping 'm1' has no parameters in common with model and does nothing
using C compiler: 'gcc.exe (GCC) 12.3.0'


i some correlations may have been dropped for the variables: `etab`, `etac`, `etad`
i the piping should specify the needed covariances directly
i change initial estimate of `etab` to `7`
i add covariance between `etac` and `etab` with initial estimate `0.2`
i change initial estimate of `etac` to `8`
i add covariance between `etad` and `etab` with initial estimate `0.3`
i add covariance between `etad` and `etac` with initial estimate `0.4`
i change initial estimate of `etad` to `9`
i change initial estimate of `etaa` to `0`
! remove population parameter `add.sd`
i add population parameter `depot` and set estimate to 1
! remove population parameter `add.sd`
i add population parameter `depot` and set estimate to 1
! remove population parameter `add.sd`
i add population parameter `depot` and set estimate to 1
i promote `temax` to population parameter with initial estimate 1
i promote `te0` to population parameter with initial estimate 1
i promote `eta.e0` to between subject variability with initial estimate 1
i promote `tec50` to population parameter with initial estimate 1
i promote `tkin` to population parameter with initial estimate 1
i promote `tkout` to population parameter with initial estimate 1
i promote `temax` to population parameter with initial estimate 1
i promote `te0` to population parameter with initial estimate 1
i promote `eta.e0` to between subject variability with initial estimate 1
i promote `tec50` to population parameter with initial estimate 1
i promote `tkin` to population parameter with initial estimate 1
i promote `tkout` to population parameter with initial estimate 1
i promote `temax` to population parameter with initial estimate 1
i promote `te0` to population parameter with initial estimate 1
i promote `eta.e0` to between subject variability with initial estimate 1
i promote `tec50` to population parameter with initial estimate 1
i promote `tkin` to population parameter with initial estimate 1
i promote `tkout` to population parameter with initial estimate 1
[ FAIL 0 | WARN 0 | SKIP 2 | PASS 1262 ]

══ Skipped tests (2) ═══════════════════════════════════════════════════════════
• On Windows (1): 'test-zzzzz.R:3:5'
• file.exists(fileCbindStudyIndividual) is not TRUE (1):
  'test-cbind-study-individual.R:40:3'

[ FAIL 0 | WARN 0 | SKIP 2 | PASS 1262 ]
> 
> ## test_check("rxode2",
> ##   stop_on_failure = FALSE,
> ##   reporter = testthat::LocationReporter
> ## )
> 
> proc.time()
   user  system elapsed 
  56.84    9.56  108.79