### Mediator model

Call:
lm(formula = bili ~ trt, data = data)

Residuals:
    Min      1Q  Median      3Q     Max 
-3.4000 -2.5000 -1.7000  0.4434 24.3000 

Coefficients:
            Estimate Std. Error t value Pr(>|t|)  
(Intercept)   2.2132     0.8784   2.520   0.0123 *
trt           0.7434     0.5532   1.344   0.1801  
---
Signif. codes:  0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1

Residual standard error: 4.594 on 274 degrees of freedom
Multiple R-squared:  0.006548,	Adjusted R-squared:  0.002923 
F-statistic: 1.806 on 1 and 274 DF,  p-value: 0.1801

### Outcome model

Call:
lm(formula = alk_phos ~ trt + bili, data = data)

Residuals:
    Min      1Q  Median      3Q     Max 
-2276.8 -1030.7  -655.3   -12.5 12053.3 

Coefficients:
            Estimate Std. Error t value Pr(>|t|)    
(Intercept)  1913.49     406.56   4.707 4.01e-06 ***
trt           -87.70     253.94  -0.345   0.7301    
bili           64.58      27.64   2.336   0.0202 *  
---
Signif. codes:  0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1

Residual standard error: 2102 on 273 degrees of freedom
Multiple R-squared:  0.01969,	Adjusted R-squared:  0.01251 
F-statistic: 2.742 on 2 and 273 DF,  p-value: 0.06624

### Mediation analysis 
             est         se          Z         p      lower     upper
cde  -105.240577 304.722222 -0.3453656 0.7298195 -702.48516 492.00400
pnde -105.240577 304.722222 -0.3453656 0.7298195 -702.48516 492.00400
tnie   57.612778  49.455722  1.1649366 0.2440447  -39.31866 154.54421
tnde -105.240577 304.722222 -0.3453656 0.7298195 -702.48516 492.00400
pnie   57.612778  49.455722  1.1649366 0.2440447  -39.31866 154.54421
te    -47.627798 306.733435 -0.1552742 0.8766051 -648.81428 553.55869
pm     -1.209646   7.983007 -0.1515276 0.8795595  -16.85605  14.43676

Evaluated at:
avar: trt
 a1 (intervened value of avar) = 2.3
 a0 (reference value of avar)  = 1.1
mvar: bili
 m_cde (intervend value of mvar for cde) = 1.4
cvar: 
 c_cond (covariate vector value) = 

Note that effect estimates do not vary over m_cde and c_cond values when interaction = FALSE.