context("basic HMM functions in backcross") test_that("backcross nalleles works", { expect_equal(nalleles("bc"), 2) }) test_that("backcross check_geno works", { # autosome expect_true(test_check_geno("bc", 0, TRUE, FALSE, FALSE, integer(0))) expect_true(test_check_geno("bc", 1, TRUE, FALSE, FALSE, integer(0))) expect_true(test_check_geno("bc", 2, TRUE, FALSE, FALSE, integer(0))) expect_true(test_check_geno("bc", 1, FALSE, FALSE, FALSE, integer(0))) expect_true(test_check_geno("bc", 2, FALSE, FALSE, FALSE, integer(0))) expect_false(test_check_geno("bc", 3, TRUE, FALSE, FALSE, integer(0))) expect_false(test_check_geno("bc", 0, FALSE, FALSE, FALSE, integer(0))) expect_false(test_check_geno("bc", 3, FALSE, FALSE, FALSE, integer(0))) # X chromosome female expect_true(test_check_geno("bc", 0, TRUE, TRUE, TRUE, integer(0))) expect_true(test_check_geno("bc", 1, TRUE, TRUE, TRUE, integer(0))) expect_true(test_check_geno("bc", 2, TRUE, TRUE, TRUE, integer(0))) expect_true(test_check_geno("bc", 1, FALSE, TRUE, TRUE, integer(0))) expect_true(test_check_geno("bc", 2, FALSE, TRUE, TRUE, integer(0))) expect_false(test_check_geno("bc", 3, TRUE, TRUE, TRUE, integer(0))) expect_false(test_check_geno("bc", 0, FALSE, TRUE, TRUE, integer(0))) expect_false(test_check_geno("bc", 3, FALSE, TRUE, TRUE, integer(0))) # X chromosome male expect_true(test_check_geno("bc", 0, TRUE, TRUE, FALSE, integer(0))) expect_true(test_check_geno("bc", 1, TRUE, TRUE, FALSE, integer(0))) expect_true(test_check_geno("bc", 3, TRUE, TRUE, FALSE, integer(0))) expect_true(test_check_geno("bc", 3, FALSE, TRUE, FALSE, integer(0))) expect_true(test_check_geno("bc", 4, FALSE, TRUE, FALSE, integer(0))) expect_false(test_check_geno("bc", 2, TRUE, TRUE, FALSE, integer(0))) expect_false(test_check_geno("bc", 4, TRUE, TRUE, FALSE, integer(0))) expect_false(test_check_geno("bc", 0, FALSE, TRUE, FALSE, integer(0))) expect_false(test_check_geno("bc", 1, FALSE, TRUE, FALSE, integer(0))) expect_false(test_check_geno("bc", 2, FALSE, TRUE, FALSE, integer(0))) expect_false(test_check_geno("bc", 5, FALSE, TRUE, FALSE, integer(0))) }) test_that("backcross n_gen works", { expect_equal(test_ngen("bc", FALSE), 2) expect_equal(test_ngen("bc", TRUE), 4) }) test_that("backcross possible_gen works", { # autosome expect_equal(test_possible_gen("bc", FALSE, FALSE, integer(0)), 1:2) # X female expect_equal(test_possible_gen("bc", TRUE, TRUE, integer(0)), 1:2) # X male expect_equal(test_possible_gen("bc", TRUE, FALSE, integer(0)), 3:4) }) test_that("backcross nrec works", { # autosome expect_equal(test_nrec("bc", 1, 1, FALSE, FALSE, integer(0)), 0) expect_equal(test_nrec("bc", 1, 2, FALSE, FALSE, integer(0)), 1) expect_equal(test_nrec("bc", 2, 1, FALSE, FALSE, integer(0)), 1) expect_equal(test_nrec("bc", 2, 2, FALSE, FALSE, integer(0)), 0) # X female expect_equal(test_nrec("bc", 1, 1, TRUE, TRUE, integer(0)), 0) expect_equal(test_nrec("bc", 1, 2, TRUE, TRUE, integer(0)), 1) expect_equal(test_nrec("bc", 2, 1, TRUE, TRUE, integer(0)), 1) expect_equal(test_nrec("bc", 2, 2, TRUE, TRUE, integer(0)), 0) # X male expect_equal(test_nrec("bc", 3, 3, TRUE, FALSE, integer(0)), 0) expect_equal(test_nrec("bc", 3, 4, TRUE, FALSE, integer(0)), 1) expect_equal(test_nrec("bc", 4, 3, TRUE, FALSE, integer(0)), 1) expect_equal(test_nrec("bc", 4, 4, TRUE, FALSE, integer(0)), 0) }) test_that("backcross init works", { # autosome expect_equal(test_init("bc", 1, FALSE, FALSE, integer(0)), log(0.5)) expect_equal(test_init("bc", 2, FALSE, FALSE, integer(0)), log(0.5)) # X female expect_equal(test_init("bc", 1, TRUE, TRUE, integer(0)), log(0.5)) expect_equal(test_init("bc", 2, TRUE, TRUE, integer(0)), log(0.5)) # X male expect_equal(test_init("bc", 3, TRUE, FALSE, integer(0)), log(0.5)) expect_equal(test_init("bc", 4, TRUE, FALSE, integer(0)), log(0.5)) }) test_that("backcross emit works", { # autosome eps <- 0.01 expect_equal(test_emit("bc", 0, 1, eps, integer(0), FALSE, FALSE, integer(0)), 0) expect_equal(test_emit("bc", 0, 2, eps, integer(0), FALSE, FALSE, integer(0)), 0) expect_equal(test_emit("bc", 1, 1, eps, integer(0), FALSE, FALSE, integer(0)), log(1-eps)) expect_equal(test_emit("bc", 1, 2, eps, integer(0), FALSE, FALSE, integer(0)), log(eps)) expect_equal(test_emit("bc", 2, 1, eps, integer(0), FALSE, FALSE, integer(0)), log(eps)) expect_equal(test_emit("bc", 2, 2, eps, integer(0), FALSE, FALSE, integer(0)), log(1-eps)) # X female expect_equal(test_emit("bc", 0, 1, eps, integer(0), TRUE, TRUE, integer(0)), 0) expect_equal(test_emit("bc", 0, 2, eps, integer(0), TRUE, TRUE, integer(0)), 0) expect_equal(test_emit("bc", 1, 1, eps, integer(0), TRUE, TRUE, integer(0)), log(1-eps)) expect_equal(test_emit("bc", 1, 2, eps, integer(0), TRUE, TRUE, integer(0)), log(eps)) expect_equal(test_emit("bc", 2, 1, eps, integer(0), TRUE, TRUE, integer(0)), log(eps)) expect_equal(test_emit("bc", 2, 2, eps, integer(0), TRUE, TRUE, integer(0)), log(1-eps)) # X male expect_equal(test_emit("bc", 0, 3, eps, integer(0), TRUE, FALSE, integer(0)), 0) expect_equal(test_emit("bc", 0, 4, eps, integer(0), TRUE, FALSE, integer(0)), 0) expect_equal(test_emit("bc", 1, 3, eps, integer(0), TRUE, FALSE, integer(0)), log(1-eps)) expect_equal(test_emit("bc", 1, 4, eps, integer(0), TRUE, FALSE, integer(0)), log(eps)) expect_equal(test_emit("bc", 3, 3, eps, integer(0), TRUE, FALSE, integer(0)), log(eps)) expect_equal(test_emit("bc", 3, 4, eps, integer(0), TRUE, FALSE, integer(0)), log(1-eps)) # errors expect_equal(test_emit("bc", 0, 0, eps, integer(0), FALSE, FALSE, integer(0)), 0) expect_equal(test_emit("bc", 0, 3, eps, integer(0), FALSE, FALSE, integer(0)), 0) expect_equal(test_emit("bc", 3, 1, eps, integer(0), FALSE, FALSE, integer(0)), 0) # X female expect_equal(test_emit("bc", 0, 0, eps, integer(0), TRUE, TRUE, integer(0)), 0) expect_equal(test_emit("bc", 0, 3, eps, integer(0), TRUE, TRUE, integer(0)), 0) expect_equal(test_emit("bc", 3, 1, eps, integer(0), TRUE, TRUE, integer(0)), 0) # X male expect_equal(test_emit("bc", 0, 0, eps, integer(0), TRUE, FALSE, integer(0)), 0) expect_equal(test_emit("bc", 0, 1, eps, integer(0), TRUE, FALSE, integer(0)), 0) expect_equal(test_emit("bc", 0, 2, eps, integer(0), TRUE, FALSE, integer(0)), 0) expect_equal(test_emit("bc", 2, 1, eps, integer(0), TRUE, FALSE, integer(0)), 0) }) test_that("backcross step works", { # autosome rf <- 0.01 expect_equal(test_step("bc", 1, 1, rf, FALSE, FALSE, integer(0)), log(1-rf)) expect_equal(test_step("bc", 1, 2, rf, FALSE, FALSE, integer(0)), log(rf)) expect_equal(test_step("bc", 2, 1, rf, FALSE, FALSE, integer(0)), log(rf)) expect_equal(test_step("bc", 2, 2, rf, FALSE, FALSE, integer(0)), log(1-rf)) # X female expect_equal(test_step("bc", 1, 1, rf, TRUE, TRUE, integer(0)), log(1-rf)) expect_equal(test_step("bc", 1, 2, rf, TRUE, TRUE, integer(0)), log(rf)) expect_equal(test_step("bc", 2, 1, rf, TRUE, TRUE, integer(0)), log(rf)) expect_equal(test_step("bc", 2, 2, rf, TRUE, TRUE, integer(0)), log(1-rf)) # X male expect_equal(test_step("bc", 3, 3, rf, TRUE, FALSE, integer(0)), log(1-rf)) expect_equal(test_step("bc", 3, 4, rf, TRUE, FALSE, integer(0)), log(rf)) expect_equal(test_step("bc", 4, 3, rf, TRUE, FALSE, integer(0)), log(rf)) expect_equal(test_step("bc", 4, 4, rf, TRUE, FALSE, integer(0)), log(1-rf)) }) test_that("geno_names works", { expect_equal(geno_names("bc", c("B", "R"), FALSE), c("BB", "BR")) expect_equal(geno_names("bc", c("B", "R"), TRUE), c("BB", "BR", "BY", "RY")) })