###### FUNCTION: bpcp2samp ###### ## Thanks to Marcel Wolbers for finding this problem. ## It used to produce a warning, but the answers were correct. ## Now should not produce a warning sim.exp <- function(n,prob1,prob2,cens.rate){ # prob1 and prob2 are the absolute risks for an event at time t=1 rate1 <- -log(1-prob1); rate2 <- -log(1-prob2) n1 <- n%/%2+n%%2; n2 <- n%/%2 ttev.uncens <- rexp(n,rate=rep(c(rate1,rate2),times=c(n1,n2))) ttcens <- rexp(n,rate=cens.rate) data.frame(arm=rep(c(0,1),c(n1,n2)),ttev=pmin(ttev.uncens,ttcens),ev=ifelse(ttev.uncens <=ttcens,1,0)) } set.seed(1) d <- sim.exp(400,prob1=0.1,prob2=0.05,cens.rate=0.05) test_that("No warning (Problem found by Marcel Wolbers)", { # no warnings expect_warning(bpcp2samp(d$ttev,d$ev,d$arm,testtime=1,parmtype="difference"), regexp = NA) }) # Possibly skip bpcp2sampControl tests - come back test_that("Error in bpcp2sampControl if stype is not km or mue", { expect_error(bpcp2sampControl(stype="test"),regexp="stype should be 'km' or 'mue', see bpcp help") }) test_that("Error in bpcp2sampControl if eps not between 0 and 0.1", { expect_error(bpcp2sampControl(eps=1),regexp="eps not in reasonable range, see help for betaMeldTest") expect_error(bpcp2sampControl(eps=-1),regexp="eps not in reasonable range, see help for betaMeldTest") }) test_that("Error in bpcp2sampControl if Delta is negative", { expect_error(bpcp2sampControl(Delta=-1),regexp="Delta is width of grouped confidence intervals, must be nonnegative") expect_error(bpcp2sampControl(Delta=0),regexp=NA) }) test_that("Error in bpcp2sampControl if nmc is a negative or non-integer ", { expect_error(bpcp2sampControl(nmc=0.1),regexp="nmc should be a non-negative integer (but can be numeric)", fixed=TRUE) expect_error(bpcp2sampControl(nmc=-1),regexp="nmc should be a non-negative integer (but can be numeric)", fixed=TRUE) }) test_that("Error in bpcp2sampControl if method is not mm.mc or mc.mc",{ expect_error(bpcp2sampControl(method="test"), regex="method should be 'mm.mc' (method of moments for 1 sample, Monte Carlo for melding) or 'mc.mc' (MC for both) ", fixed=TRUE) }) test_that("Error in bpcp2samp if group does not have at least 2 levels",{ expect_error(bpcp2samp(time=leuk2$time,status=leuk2$status,group=rep(1,nrow(leuk2)), testtime=9), regexp = "group does not have 2 levels") }) test_that("Error in bpcp2samp if length of time, status and group are not the same",{ expect_error(bpcp2samp(time=leuk2$time,status=leuk2$status,group=leuk2$treatment[-1], testtime=9), regexp="length of time, status and group should be the same") expect_error(bpcp2samp(time=leuk2$time,status=leuk2$status[-1],group=leuk2$treatment, testtime=9), regexp="length of time, status and group should be the same") expect_error(bpcp2samp(time=leuk2$time[-1],status=leuk2$status,group=leuk2$treatment, testtime=9), regexp="length of time, status and group should be the same") }) test_that("Error in bpcp2samp if testime is not positive",{ expect_error(bpcp2samp(time=leuk2$time,status=leuk2$status,group=leuk2$treatment, testtime=-1), regexp="testtime must be positive and a vector of length 1") }) test_that("Error in bpcp2samp if testime is not a vector of length 1",{ expect_error(bpcp2samp(time=leuk2$time,status=leuk2$status,group=leuk2$treatment, testtime=c(9,13)), regexp="testtime must be positive and a vector of length 1") }) test_that("Error in bpcp2samp if alternative is not correctly specified", { expect_error(bpcp2samp(time=leuk2$time,status=leuk2$status,group=leuk2$treatment, testtime=9,alternative = "test"), regexp = '\'arg\' should be one of "two.sided", "less", "greater"') }) test_that("Error in bpcp2samp if add.eps is >= minimum time difference",{ time <- c(1,2,3,5,5) status <- c(1,1,1,1,1) group <- c("T","C","C","C","T") expect_error(bpcp2samp(time=time,status=status,group=group, testtime=5, add.eps=1), regexp="Minimum difference between consecutive timepoints is 1. add.eps is greater than or equal to this and needs to be reduced.") }) test_that("Warning in bpcp2samp if add.eps is >= 0.5 minimum time difference",{ time <- c(1,2,3,5,5) status <- c(1,1,1,1,1) group <- c("T","C","C","C","T") expect_warning(bpcp2samp(time=time,status=status,group=group, testtime=5, add.eps=0.5), regexp="Minimum difference between consecutive timepoints is 1. add.eps is on the same order as this and should be reduced.") }) test_that("Two sample test works on differences with no censoring and matches Fisher's exact - time 1", { expect_equal(no_censoring(time=1,type="bpcp",arms=2,param="ci"), exact2x2::binomMeld.test(1,3,3,3, parmtype = "difference")$conf.int) expect_equal(no_censoring(time=1,type="bpcp",arms=2,param="p"), exact2x2::binomMeld.test(1,3,3,3, parmtype = "difference")$p.value) expect_equal(no_censoring(time=1,type="bpcp",arms=2,param="p"), exact2x2::exact2x2(matrix(c(2,1,0,3), nrow=2, ncol=2), tsmethod = "central")$p.value, tolerance = 1e-6) }) test_that("Two sample test works on differences with no censoring and matches Fisher's exact - time 2", { expect_equal(no_censoring(time=2,type="bpcp",arms=2,param="ci"), exact2x2::binomMeld.test(0,3,3,3, parmtype = "difference")$conf.int) expect_equal(no_censoring(time=2,type="bpcp",arms=2,param="p"), exact2x2::binomMeld.test(0,3,3,3, parmtype = "difference")$p.value) expect_equal(no_censoring(time=2,type="bpcp",arms=2,param="p"), exact2x2::exact2x2(matrix(c(3,0,0,3), nrow=2, ncol=2), tsmethod = "central")$p.value, tolerance = 1e-6) }) test_that("Two sample test works on differences with no censoring and matches Fisher's exact - time 3", { expect_equal(no_censoring(time=3,type="bpcp",arms=2,param="ci"), exact2x2::binomMeld.test(0,3,2,3, parmtype = "difference")$conf.int) expect_equal(no_censoring(time=3,type="bpcp",arms=2,param="p"), exact2x2::binomMeld.test(0,3,2,3, parmtype = "difference")$p.value) expect_equal(no_censoring(time=3,type="bpcp",arms=2,param="p"), exact2x2::exact2x2(matrix(c(3,0,1,2), nrow=2, ncol=2), tsmethod = "central")$p.value, tolerance = 1e-6) }) test_that("Two sample test works on differences with no censoring and matches Fisher's exact - time 4", { expect_equal(no_censoring(time=4,type="bpcp",arms=2,param="ci"), exact2x2::binomMeld.test(0,3,1,3, parmtype = "difference")$conf.int) expect_equal(no_censoring(time=4,type="bpcp",arms=2,param="p"), exact2x2::binomMeld.test(0,3,1,3, parmtype = "difference")$p.value) expect_equal(no_censoring(time=4,type="bpcp",arms=2,param="p"), exact2x2::exact2x2(matrix(c(3,0,2,1), nrow=2, ncol=2), tsmethod = "central")$p.value, tolerance = 1e-6) }) test_that("Two sample test works on differences with no censoring and matches Fisher's exact - time 5", { expect_equal(no_censoring(time=5,type="bpcp",arms=2,param="ci"), exact2x2::binomMeld.test(0,3,0,3, parmtype = "difference")$conf.int) expect_equal(no_censoring(time=5,type="bpcp",arms=2,param="p"), exact2x2::binomMeld.test(0,3,0,3, parmtype = "difference")$p.value) expect_equal(no_censoring(time=5,type="bpcp",arms=2,param="p"), exact2x2::exact2x2(matrix(c(3,0,3,0), nrow=2, ncol=2), tsmethod = "central")$p.value, tolerance = 1e-6) }) # Odds Ratio test_that("Two sample test works on odds ratios with no censoring - time 1", { expect_equal(no_censoring(time=1,type="bpcp",arms=2,param="ci", parmtype = "oddsratio"), exact2x2::binomMeld.test(1,3,3,3, parmtype = "oddsratio")$conf.int) expect_equal(no_censoring(time=1,type="bpcp",arms=2,param="p", parmtype = "oddsratio"), exact2x2::binomMeld.test(1,3,3,3, parmtype = "oddsratio")$p.value) }) test_that("Two sample test works on odds ratios with no censoring - time 2", { expect_equal(no_censoring(time=2,type="bpcp",arms=2,param="ci", parmtype = "oddsratio"), exact2x2::binomMeld.test(0,3,3,3, parmtype = "oddsratio")$conf.int) expect_equal(no_censoring(time=2,type="bpcp",arms=2,param="p", parmtype = "oddsratio"), exact2x2::binomMeld.test(0,3,3,3, parmtype = "oddsratio")$p.value) }) test_that("Two sample test works on odds ratios with no censoring - time 3", { expect_equal(no_censoring(time=3,type="bpcp",arms=2,param="ci", parmtype = "oddsratio"), exact2x2::binomMeld.test(0,3,2,3, parmtype = "oddsratio")$conf.int) expect_equal(no_censoring(time=3,type="bpcp",arms=2,param="p", parmtype = "oddsratio"), exact2x2::binomMeld.test(0,3,2,3, parmtype = "oddsratio")$p.value) }) test_that("Two sample test works on odds ratios with no censoring - time 4", { expect_equal(no_censoring(time=4,type="bpcp",arms=2,param="ci", parmtype = "oddsratio"), exact2x2::binomMeld.test(0,3,1,3, parmtype = "oddsratio")$conf.int) expect_equal(no_censoring(time=4,type="bpcp",arms=2,param="p", parmtype = "oddsratio"), exact2x2::binomMeld.test(0,3,1,3, parmtype = "oddsratio")$p.value) }) test_that("Two sample test works on odds ratios with no censoring - time 5", { expect_equal(no_censoring(time=5,type="bpcp",arms=2,param="ci", parmtype = "oddsratio"), exact2x2::binomMeld.test(0,3,0,3, parmtype = "oddsratio")$conf.int) expect_equal(no_censoring(time=5,type="bpcp",arms=2,param="p", parmtype = "oddsratio"), exact2x2::binomMeld.test(0,3,0,3, parmtype = "oddsratio")$p.value) }) # Ratio test_that("Two sample test works on ratios with no censoring - time 1", { expect_equal(no_censoring(time=1,type="bpcp",arms=2,param="ci", parmtype = "ratio"), exact2x2::binomMeld.test(1,3,3,3, parmtype = "ratio")$conf.int) expect_equal(no_censoring(time=1,type="bpcp",arms=2,param="p", parmtype = "ratio"), exact2x2::binomMeld.test(1,3,3,3, parmtype = "ratio")$p.value) }) test_that("Two sample test works on ratios with no censoring - time 2", { expect_equal(no_censoring(time=2,type="bpcp",arms=2,param="ci", parmtype = "ratio"), exact2x2::binomMeld.test(0,3,3,3, parmtype = "ratio")$conf.int) expect_equal(no_censoring(time=2,type="bpcp",arms=2,param="p", parmtype = "ratio"), exact2x2::binomMeld.test(0,3,3,3, parmtype = "ratio")$p.value) }) test_that("Two sample test works on ratios with no censoring - time 3", { expect_equal(no_censoring(time=3,type="bpcp",arms=2,param="ci", parmtype = "ratio"), exact2x2::binomMeld.test(0,3,2,3, parmtype = "ratio")$conf.int) expect_equal(no_censoring(time=3,type="bpcp",arms=2,param="p", parmtype = "ratio"), exact2x2::binomMeld.test(0,3,2,3, parmtype = "ratio")$p.value) }) test_that("Two sample test works on ratios with no censoring - time 4", { expect_equal(no_censoring(time=4,type="bpcp",arms=2,param="ci", parmtype = "ratio"), exact2x2::binomMeld.test(0,3,1,3, parmtype = "ratio")$conf.int) expect_equal(no_censoring(time=4,type="bpcp",arms=2,param="p", parmtype = "ratio"), exact2x2::binomMeld.test(0,3,1,3, parmtype = "ratio")$p.value) }) test_that("Two sample test works on ratios with no censoring - time 5", { expect_equal(no_censoring(time=5,type="bpcp",arms=2,param="ci", parmtype = "ratio"), exact2x2::binomMeld.test(0,3,0,3, parmtype = "ratio")$conf.int) expect_equal(no_censoring(time=5,type="bpcp",arms=2,param="p", parmtype = "ratio"), exact2x2::binomMeld.test(0,3,0,3, parmtype = "ratio")$p.value) }) test_that("Mid-p for odds ratio with no censoring matches exact2x2 mid-p (Melded Binomial) - time 1", { skip_on_cran() expect_equal(no_censoring(time=1,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",midp=T)[1:2], exact2x2::binomMeld.test(0,3,2,3, parmtype = "oddsratio",midp=T)$conf.int[1:2], tolerance=0.01) expect_equal(no_censoring(time=1,type="bpcp",arms=2,param="p", parmtype = "oddsratio",midp=T), exact2x2::binomMeld.test(0,3,2,3, parmtype = "oddsratio",midp=T)$p.value,tolerance=0.01) }) test_that("Mid-p for odds ratio with no censoring matches exact2x2 mid-p (Melded Binomial) - time 2", { skip_on_cran() expect_equal(no_censoring(time=2,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",midp=T)[1:2], exact2x2::binomMeld.test(0,3,3,3, parmtype = "oddsratio",midp=T)$conf.int[1:2], tolerance=0.01) expect_equal(no_censoring(time=2,type="bpcp",arms=2,param="p", parmtype = "oddsratio",midp=T), exact2x2::binomMeld.test(0,3,3,3, parmtype = "oddsratio",midp=T)$p.value,tolerance=0.01) }) test_that("Mid-p for odds ratio with no censoring matches exact2x2 mid-p (Melded Binomial) - time 3", { skip_on_cran() expect_equal(no_censoring(time=3,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",midp=T)[1:2], exact2x2::binomMeld.test(1,3,3,3, parmtype = "oddsratio",midp=T)$conf.int[1:2], tolerance=0.01) expect_equal(no_censoring(time=3,type="bpcp",arms=2,param="p", parmtype = "oddsratio",midp=T), exact2x2::binomMeld.test(1,3,3,3, parmtype = "oddsratio",midp=T)$p.value,tolerance=0.01) }) test_that("Mid-p for odds ratio with no censoring matches exact2x2 mid-p (Melded Binomial) - time 4", { skip_on_cran() expect_equal(no_censoring(time=4,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",midp=T)[1:2], exact2x2::binomMeld.test(2,3,3,3, parmtype = "oddsratio",midp=T)$conf.int[1:2], tolerance=0.01) expect_equal(no_censoring(time=4,type="bpcp",arms=2,param="p", parmtype = "oddsratio",midp=T), exact2x2::binomMeld.test(2,3,3,3, parmtype = "oddsratio",midp=T)$p.value,tolerance=0.01) }) test_that("Mid-p for odds ratio with no censoring matches exact2x2 mid-p (Melded Binomial) - time 5", { skip_on_cran() expect_equal(no_censoring(time=5,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",midp=T)[1:2], exact2x2::binomMeld.test(0,3,0,3, parmtype = "oddsratio",midp=T)$conf.int[1:2], tolerance=0.01) expect_equal(no_censoring(time=5,type="bpcp",arms=2,param="p", parmtype = "oddsratio",midp=T), exact2x2::binomMeld.test(0,3,0,3, parmtype = "oddsratio",midp=T)$p.value,tolerance=0.01) }) # conf.level test_that("90% for odds ratio with no censoring matches exact2x2 (Melded Binomial) - time 1", { expect_equal(no_censoring(time=1,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",conf.level = 0.9)[1:2], exact2x2::binomMeld.test(0,3,2,3, parmtype = "oddsratio",conf.level = 0.9)$conf.int[1:2], tolerance=0.01) }) test_that("90% for odds ratio with no censoring matches exact2x2 (Melded Binomial) - time 2", { expect_equal(no_censoring(time=2,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",conf.level = 0.9)[1:2], exact2x2::binomMeld.test(0,3,3,3, parmtype = "oddsratio",conf.level = 0.9)$conf.int[1:2], tolerance=0.01) }) test_that("90% for odds ratio with no censoring matches exact2x2 (Melded Binomial) - time 3", { expect_equal(no_censoring(time=3,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",conf.level = 0.9)[1:2], exact2x2::binomMeld.test(1,3,3,3, parmtype = "oddsratio",conf.level = 0.9)$conf.int[1:2], tolerance=0.01) }) test_that("90% for odds ratio with no censoring matches exact2x2 (Melded Binomial) - time 4", { expect_equal(no_censoring(time=4,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",conf.level = 0.9)[1:2], exact2x2::binomMeld.test(2,3,3,3, parmtype = "oddsratio",conf.level = 0.9)$conf.int[1:2], tolerance=0.01) }) test_that("90% for odds ratio with no censoring matches exact2x2 (Melded Binomial) - time 5", { expect_equal(no_censoring(time=5,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",conf.level = 0.9)[1:2], exact2x2::binomMeld.test(0,3,0,3, parmtype = "oddsratio",conf.level = 0.9)$conf.int[1:2], tolerance=0.01) }) # nullparm test_that("Nullparm = 0.5 p-value for odds ratio with no censoring matches exact2x2 (Melded Binomial) - time 1", { expect_equal(no_censoring(time=1,type="bpcp",arms=2,param="p", parmtype = "oddsratio",nullparm=0.5), exact2x2::binomMeld.test(0,3,2,3, parmtype = "oddsratio",nullparm=0.5)$p.value, tolerance=0.01) expect_false(identical(no_censoring(time=1,type="bpcp",arms=2,param="p", parmtype = "oddsratio",nullparm=0.5), no_censoring(time=1,type="bpcp",arms=2,param="p", parmtype = "oddsratio"))) }) test_that("Nullparm = 0.5 p-value for odds ratio with no censoring matches exact2x2 (Melded Binomial) - time 2", { expect_equal(no_censoring(time=2,type="bpcp",arms=2,param="p", parmtype = "oddsratio",nullparm=0.5), exact2x2::binomMeld.test(0,3,3,3, parmtype = "oddsratio",nullparm=0.5)$p.value, tolerance=0.01) expect_false(identical(no_censoring(time=2,type="bpcp",arms=2,param="p", parmtype = "oddsratio",nullparm=0.5), no_censoring(time=2,type="bpcp",arms=2,param="p", parmtype = "oddsratio"))) }) test_that("Nullparm = 0.5 p-value for odds ratio with no censoring matches exact2x2 (Melded Binomial) - time 3", { expect_equal(no_censoring(time=3,type="bpcp",arms=2,param="p", parmtype = "oddsratio",nullparm=0.5), exact2x2::binomMeld.test(1,3,3,3, parmtype = "oddsratio",nullparm=0.5)$p.value, tolerance=0.01) expect_false(identical(no_censoring(time=3,type="bpcp",arms=2,param="p", parmtype = "oddsratio",nullparm=0.5), no_censoring(time=3,type="bpcp",arms=2,param="p", parmtype = "oddsratio"))) }) test_that("Nullparm = 0.5 p-value for odds ratio with no censoring matches exact2x2 (Melded Binomial) - time 4", { expect_equal(no_censoring(time=4,type="bpcp",arms=2,param="p", parmtype = "oddsratio",nullparm=0.5), exact2x2::binomMeld.test(2,3,3,3, parmtype = "oddsratio",nullparm=0.5)$p.value, tolerance=0.01) expect_false(identical(no_censoring(time=4,type="bpcp",arms=2,param="p", parmtype = "oddsratio",nullparm=0.5), no_censoring(time=4,type="bpcp",arms=2,param="p", parmtype = "oddsratio"))) }) test_that("Nullparm = 0.5 p-value for odds ratio with no censoring matches exact2x2 (Melded Binomial) - time 5", { expect_equal(no_censoring(time=5,type="bpcp",arms=2,param="p", parmtype = "oddsratio",nullparm=0.5), exact2x2::binomMeld.test(0,3,0,3, parmtype = "oddsratio",nullparm=0.5)$p.value, tolerance=0.01) }) # alternative test_that("Alternative = less for odds ratio with no censoring matches exact2x2 (Melded Binomial) - time 1", { expect_equal(no_censoring(time=1,type="bpcp",arms=2,param="p", parmtype = "oddsratio",alternative="less"), exact2x2::binomMeld.test(0,3,2,3, parmtype = "oddsratio",alternative="less")$p.value, tolerance=0.01) expect_equal(no_censoring(time=1,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",alternative="less")[1:2], exact2x2::binomMeld.test(0,3,2,3, parmtype = "oddsratio",alternative="less")$conf.int[1:2], tolerance=0.01) expect_false(identical(no_censoring(time=1,type="bpcp",arms=2,param="p", parmtype = "oddsratio",alternative="less"), no_censoring(time=1,type="bpcp",arms=2,param="p", parmtype = "oddsratio"))) expect_false(identical(no_censoring(time=1,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",alternative="less")[1:2], no_censoring(time=1,type="bpcp",arms=2,param="ci", parmtype = "oddsratio")[1:2])) }) test_that("Alternative = greater for odds ratio with no censoring matches exact2x2 (Melded Binomial) - time 1", { expect_equal(no_censoring(time=1,type="bpcp",arms=2,param="p", parmtype = "oddsratio",alternative="greater"), exact2x2::binomMeld.test(0,3,2,3, parmtype = "oddsratio",alternative="greater")$p.value, tolerance=0.01) expect_equal(no_censoring(time=1,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",alternative="greater")[1:2], exact2x2::binomMeld.test(0,3,2,3, parmtype = "oddsratio",alternative="greater")$conf.int[1:2], tolerance=0.01) expect_false(identical(no_censoring(time=1,type="bpcp",arms=2,param="p", parmtype = "oddsratio",alternative="greater"), no_censoring(time=1,type="bpcp",arms=2,param="p", parmtype = "oddsratio"))) expect_false(identical(no_censoring(time=1,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",alternative="greater")[1:2], no_censoring(time=1,type="bpcp",arms=2,param="ci", parmtype = "oddsratio")[1:2])) }) test_that("Alternative = greater does not give same results as alternative = less (time 1, no censoring)", { expect_false(identical(no_censoring(time=1,type="bpcp",arms=2,param="p", parmtype = "oddsratio",alternative="less"), no_censoring(time=1,type="bpcp",arms=2,param="p", parmtype = "oddsratio",alternative="greater"))) expect_false(identical(no_censoring(time=1,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",alternative="less")[1:2], no_censoring(time=1,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",alternative="greater")[1:2])) }) test_that("Alternative = less for odds ratio with no censoring matches exact2x2 (Melded Binomial) - time 2", { expect_equal(no_censoring(time=2,type="bpcp",arms=2,param="p", parmtype = "oddsratio",alternative = "less"), exact2x2::binomMeld.test(0,3,3,3, parmtype = "oddsratio",alternative = "less")$p.value, tolerance=0.01) expect_equal(no_censoring(time=2,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",alternative = "less")[1:2], exact2x2::binomMeld.test(0,3,3,3, parmtype = "oddsratio",alternative = "less")$conf.int[1:2], tolerance=0.01) expect_false(identical(no_censoring(time=2,type="bpcp",arms=2,param="p", parmtype = "oddsratio",alternative = "less"), no_censoring(time=2,type="bpcp",arms=2,param="p", parmtype = "oddsratio"))) expect_false(identical(no_censoring(time=2,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",alternative = "less")[1:2], no_censoring(time=2,type="bpcp",arms=2,param="ci", parmtype = "oddsratio")[1:2])) }) test_that("Alternative = greater for odds ratio with no censoring matches exact2x2 (Melded Binomial) - time 2", { expect_equal(no_censoring(time=2,type="bpcp",arms=2,param="p", parmtype = "oddsratio",alternative = "greater"), exact2x2::binomMeld.test(0,3,3,3, parmtype = "oddsratio",alternative = "greater")$p.value, tolerance=0.01) expect_equal(no_censoring(time=2,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",alternative = "greater")[1:2], exact2x2::binomMeld.test(0,3,3,3, parmtype = "oddsratio",alternative = "greater")$conf.int[1:2], tolerance=0.01) expect_false(identical(no_censoring(time=2,type="bpcp",arms=2,param="p", parmtype = "oddsratio",alternative = "greater"), no_censoring(time=2,type="bpcp",arms=2,param="p", parmtype = "oddsratio"))) expect_false(identical(no_censoring(time=2,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",alternative = "greater")[1:2], no_censoring(time=2,type="bpcp",arms=2,param="ci", parmtype = "oddsratio")[1:2])) }) test_that("Alternative = greater does not give same results as alternative = less (time 2, no censoring)", { expect_false(identical(no_censoring(time=2,type="bpcp",arms=2,param="p", parmtype = "oddsratio",alternative="less"), no_censoring(time=2,type="bpcp",arms=2,param="p", parmtype = "oddsratio",alternative="greater"))) expect_false(identical(no_censoring(time=2,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",alternative="less")[1:2], no_censoring(time=2,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",alternative="greater")[1:2])) }) test_that("Alternative = less for odds ratio with no censoring matches exact2x2 (Melded Binomial) - time 3", { expect_equal(no_censoring(time=3,type="bpcp",arms=2,param="p", parmtype = "oddsratio",alternative = "less"), exact2x2::binomMeld.test(1,3,3,3, parmtype = "oddsratio",alternative = "less")$p.value, tolerance=0.01) expect_equal(no_censoring(time=3,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",alternative = "less")[1:2], exact2x2::binomMeld.test(1,3,3,3, parmtype = "oddsratio",alternative = "less")$conf.int[1:2], tolerance=0.01) expect_false(identical(no_censoring(time=3,type="bpcp",arms=2,param="p", parmtype = "oddsratio",alternative = "less"), no_censoring(time=3,type="bpcp",arms=2,param="p", parmtype = "oddsratio"))) expect_false(identical(no_censoring(time=3,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",alternative = "less")[1:2], no_censoring(time=3,type="bpcp",arms=2,param="ci", parmtype = "oddsratio")[1:2])) }) test_that("Alternative = greater does not give same results as alternative = less (time 3, no censoring)", { expect_false(identical(no_censoring(time=3,type="bpcp",arms=2,param="p", parmtype = "oddsratio",alternative="less"), no_censoring(time=3,type="bpcp",arms=2,param="p", parmtype = "oddsratio",alternative="greater"))) expect_false(identical(no_censoring(time=3,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",alternative="less")[1:2], no_censoring(time=3,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",alternative="greater")[1:2])) }) test_that("Alternative = greater for odds ratio with no censoring matches exact2x2 (Melded Binomial) - time 3", { expect_equal(no_censoring(time=3,type="bpcp",arms=2,param="p", parmtype = "oddsratio",alternative = "greater"), exact2x2::binomMeld.test(1,3,3,3, parmtype = "oddsratio",alternative = "greater")$p.value, tolerance=0.01) expect_equal(no_censoring(time=3,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",alternative = "greater")[1:2], exact2x2::binomMeld.test(1,3,3,3, parmtype = "oddsratio",alternative = "greater")$conf.int[1:2], tolerance=0.01) expect_false(identical(no_censoring(time=3,type="bpcp",arms=2,param="p", parmtype = "oddsratio",alternative = "greater"), no_censoring(time=3,type="bpcp",arms=2,param="p", parmtype = "oddsratio"))) expect_false(identical(no_censoring(time=3,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",alternative = "greater")[1:2], no_censoring(time=3,type="bpcp",arms=2,param="ci", parmtype = "oddsratio")[1:2])) }) test_that("Alternative = less for odds ratio with no censoring matches exact2x2 (Melded Binomial) - time 4", { expect_equal(no_censoring(time=4,type="bpcp",arms=2,param="p", parmtype = "oddsratio",alternative = "less"), exact2x2::binomMeld.test(2,3,3,3, parmtype = "oddsratio",alternative = "less")$p.value, tolerance=0.01) expect_equal(no_censoring(time=4,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",alternative = "less")[1:2], exact2x2::binomMeld.test(2,3,3,3, parmtype = "oddsratio",alternative = "less")$conf.int[1:2], tolerance=0.01) }) test_that("Alternative = greater for odds ratio with no censoring matches exact2x2 (Melded Binomial) - time 4", { expect_equal(no_censoring(time=4,type="bpcp",arms=2,param="p", parmtype = "oddsratio",alternative = "greater"), exact2x2::binomMeld.test(2,3,3,3, parmtype = "oddsratio",alternative = "greater")$p.value, tolerance=0.01) expect_equal(no_censoring(time=4,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",alternative = "greater")[1:2], exact2x2::binomMeld.test(2,3,3,3, parmtype = "oddsratio",alternative = "greater")$conf.int[1:2], tolerance=0.01) expect_false(identical(no_censoring(time=4,type="bpcp",arms=2,param="p", parmtype = "oddsratio",alternative = "greater"), no_censoring(time=4,type="bpcp",arms=2,param="p", parmtype = "oddsratio"))) expect_false(identical(no_censoring(time=4,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",alternative = "greater")[1:2], no_censoring(time=4,type="bpcp",arms=2,param="ci", parmtype = "oddsratio")[1:2])) }) test_that("Alternative = greater does not give same results as alternative = less (time 4, no censoring)", { expect_false(identical(no_censoring(time=4,type="bpcp",arms=2,param="p", parmtype = "oddsratio",alternative="less"), no_censoring(time=4,type="bpcp",arms=2,param="p", parmtype = "oddsratio",alternative="greater"))) expect_false(identical(no_censoring(time=4,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",alternative="less")[1:2], no_censoring(time=4,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",alternative="greater")[1:2])) }) test_that("Alternative = less for odds ratio with no censoring matches exact2x2 (Melded Binomial) - time 5", { expect_equal(no_censoring(time=5,type="bpcp",arms=2,param="p", parmtype = "oddsratio",alternative = "less"), exact2x2::binomMeld.test(0,3,0,3, parmtype = "oddsratio",alternative = "less")$p.value, tolerance=0.01) expect_equal(no_censoring(time=5,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",alternative = "less")[1:2], exact2x2::binomMeld.test(0,3,0,3, parmtype = "oddsratio",alternative = "less")$conf.int[1:2], tolerance=0.01) }) test_that("Alternative = greater for odds ratio with no censoring matches exact2x2 (Melded Binomial) - time 5", { expect_equal(no_censoring(time=5,type="bpcp",arms=2,param="p", parmtype = "oddsratio",alternative = "greater"), exact2x2::binomMeld.test(0,3,0,3, parmtype = "oddsratio",alternative = "greater")$p.value, tolerance=0.01) expect_equal(no_censoring(time=5,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",alternative = "greater")[1:2], exact2x2::binomMeld.test(0,3,0,3, parmtype = "oddsratio",alternative = "greater")$conf.int[1:2], tolerance=0.01) }) # changeGroupOrder test_that("changeGroupOrder for odds ratio with no censoring matches exact2x2 (Melded Binomial) - time 1", { expect_equal(no_censoring(time=1,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",changeGroupOrder = T)[1:2], exact2x2::binomMeld.test(2,3,0,3, parmtype = "oddsratio")$conf.int[1:2], tolerance=0.01) }) test_that("changeGroupOrder for odds ratio with no censoring matches exact2x2 (Melded Binomial) - time 2", { expect_equal(no_censoring(time=2,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",changeGroupOrder = T)[1:2], exact2x2::binomMeld.test(3,3,0,3, parmtype = "oddsratio")$conf.int[1:2], tolerance=0.01) }) test_that("changeGroupOrder for odds ratio with no censoring matches exact2x2 (Melded Binomial) - time 3", { expect_equal(no_censoring(time=3,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",changeGroupOrder = T)[1:2], exact2x2::binomMeld.test(3,3,1,3, parmtype = "oddsratio")$conf.int[1:2], tolerance=0.01) }) test_that("changeGroupOrder for odds ratio with no censoring matches exact2x2 (Melded Binomial) - time 4", { expect_equal(no_censoring(time=4,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",changeGroupOrder = T)[1:2], exact2x2::binomMeld.test(3,3,2,3, parmtype = "oddsratio")$conf.int[1:2], tolerance=0.01) }) test_that("changeGroupOrder for odds ratio with no censoring matches exact2x2 (Melded Binomial) - time 5", { expect_equal(no_censoring(time=5,type="bpcp",arms=2,param="ci", parmtype = "oddsratio",changeGroupOrder = T)[1:2], exact2x2::binomMeld.test(0,3,0,3, parmtype = "oddsratio")$conf.int[1:2], tolerance=0.01) }) test_that("add.eps= 0 gives same results with no censoring", { time <- c(1,2,3,5,5) status <- c(1,1,1,1,1) group <- c("T","C","C","C","T") expect_equal(bpcp2samp(time,status,group,5,add.eps=0), bpcp2samp(time,status,group,5)) }) test_that("add.eps= 0 gives different results than 1e-10 when one group is censored at testtime", { # example dataset where all are censored in one group set.seed(1) n<-10 y0<- rep(28,n) #y0<-c(48*runif(n/2),rep(28+1e-10,n/2)) y1<- 28*runif(n) y<-c(y0,y1) #cens<-rep(28,2*n) status<- c(rep(0,n),rep(1,n)) #status<- ifelse(y<=cens,1,0) group<- c(rep(0,n),rep(1,n)) # when add.eps = 0, expect p-value = 1 expect_equal(unname(bpcp2samp(y,status,group,testtime=28,add.eps=0)$p.value), 1) # when add.eps = 1e-10, expect p-value to be < .001 expect_lt(unname(bpcp2samp(y,status,group,testtime=28)$p.value), 0.001) # Also expect upper CI of add.eps = 0 > add.eps = 1e-10 expect_lt(bpcp2samp(y,status,group,testtime=28)$conf.int[2], bpcp2samp(y,status,group,testtime=28, add.eps=0)$conf.int[2]) }) # We expect that if we test a null hypothesis and get a p-value of p # with a null parameter value of beta_0 # then the 100(1-p)% confidence interval for beta # should have one of its limits equal to (or at least very close to) beta_0 test_that("Compatability of p-value and confidence limit (non-extreme data) - difference, less", { expect_equal( pvalue.CI.compatability(3,12,9,24,"difference","less",0.2),0.2, tolerance=0.001) }) test_that("Compatability of p-value and confidence limit (non-extreme data) - difference, greater", { expect_equal( pvalue.CI.compatability(3,12,9,24,"difference","greater",0.2),0.2, tolerance=0.001) }) test_that("Compatability of p-value and confidence limit (non-extreme data) - ratio, less ", { expect_equal( pvalue.CI.compatability(3,12,9,24,"ratio","less",0.3),0.3, tolerance=0.001) }) test_that("Compatability of p-value and confidence limit (non-extreme data) - ratio, greater", { expect_equal( pvalue.CI.compatability(3,12,9,24,"ratio","greater",0.3),0.3, tolerance=0.001) }) test_that("Compatability of p-value and confidence limit (non-extreme data) - oddsratio, less", { expect_equal( pvalue.CI.compatability(3,12,9,24,"oddsratio","less",0.3),0.3, tolerance=0.001) }) test_that("Compatability of p-value and confidence limit (non-extreme data) - oddsratio, greater", { expect_equal( pvalue.CI.compatability(3,12,9,24,"oddsratio","greater",0.3),0.3, tolerance=0.001) }) test_that("Compatability of p-value and confidence limit (non-extreme data) - cdfratio, less", { expect_equal( pvalue.CI.compatability(3,12,9,24,"cdfratio","less",0.3),0.3, tolerance=0.001) }) test_that("Compatability of p-value and confidence limit (non-extreme data) - cdfratio, greater", { expect_equal( pvalue.CI.compatability(3,12,9,24,"cdfratio","greater",0.3),0.3, tolerance=0.001) }) test_that("Compatability of p-value and confidence limit (non-extreme data) - logsratio, less", { expect_equal( pvalue.CI.compatability(3,12,9,24,"logsratio","less",0.3),0.3, tolerance=0.001) }) test_that("Compatability of p-value and confidence limit (non-extreme data) - logsratio, greater", { expect_equal( pvalue.CI.compatability(3,12,9,24,"logsratio","greater",0.3),0.3, tolerance=0.001) }) test_that("Compatability of p-value and confidence limit (non-extreme data) - effcdf, less", { expect_equal( pvalue.CI.compatability(3,12,9,24,"effcdf","less",1-1/0.3),1-1/0.3, tolerance=0.001) }) test_that("Compatability of p-value and confidence limit (non-extreme data) - effcdf, greater", { expect_equal( pvalue.CI.compatability(3,12,9,24,"effcdf","greater",1-1/0.3),1-1/0.3, tolerance=0.001) }) test_that("Compatability of p-value and confidence limit (non-extreme data) - efflogs, less", { expect_equal( pvalue.CI.compatability(3,12,9,24,"efflogs","less",1-1/0.3),1-1/0.3, tolerance=0.001) }) test_that("Compatability of p-value and confidence limit (non-extreme data - efflogs, greater)", { expect_equal( pvalue.CI.compatability(3,12,9,24,"efflogs","greater",1-1/0.3),1-1/0.3, tolerance=0.001) }) test_that("Compatability of p-value and confidence limit (extreme data) - difference, less)", { # x1=0, cannot expect good tolerance if # p-value is too small (very close to 0) or too big (very close to 1) # so pick nullparm to avoid those situations expect_equal( pvalue.CI.compatability(0,12,9,24,"difference","less",0.2),0.2, tolerance=0.001) # x2=0, cannot expect good tolerance if # p-value is too small (very close to 0) or too big (very close to 1) # so pick nullparm to avoid those situations expect_equal( pvalue.CI.compatability(3,12,0,24,"difference","less",-0.2),-0.2, tolerance=0.001) # x1=n1, cannot expect good tolerance if # p-value is too small (very close to 0) or too big (very close to 1) # so pick nullparm to avoid those situations expect_equal( pvalue.CI.compatability(12,12,9,24,"difference","less",-0.2),-0.2, tolerance=0.001) # x2=n2, cannot expect good tolerance if # p-value is too small (very close to 0) or too big (very close to 1) # so pick nullparm to avoid those situations expect_equal( pvalue.CI.compatability(3,12,24,24,"difference","less",0.9),0.9, tolerance=0.001) # x1=n1, x2=n2, pick nullparm carefully expect_equal( pvalue.CI.compatability(12,12,24,24,"difference","less",0.1),0.1, tolerance=0.001) # x1=0, x2=0, pick nullparm carefully expect_equal( pvalue.CI.compatability(0,12,0,24,"difference","less",0.1),0.1, tolerance=0.001) }) test_that("Compatability of p-value and confidence limit (extreme data) - difference, greater)", { # x1=0, cannot expect good tolerance if # p-value is too small (very close to 0) or too big (very close to 1) # so pick nullparm to avoid those situations expect_equal( pvalue.CI.compatability(0,12,9,24,"difference","greater",0.2),0.2, tolerance=0.001) # x2=0, cannot expect good tolerance if # p-value is too small (very close to 0) or too big (very close to 1) # so pick nullparm to avoid those situations expect_equal( pvalue.CI.compatability(3,12,0,24,"difference","greater",-0.2),-0.2, tolerance=0.001) # x1=n1, cannot expect good tolerance if # p-value is too small (very close to 0) or too big (very close to 1) # so pick nullparm to avoid those situations expect_equal( pvalue.CI.compatability(12,12,9,24,"difference","greater",-0.9),-0.9, tolerance=0.001) # x2=n2, cannot expect good tolerance if # p-value is too small (very close to 0) or too big (very close to 1) # so pick nullparm to avoid those situations expect_equal( pvalue.CI.compatability(3,12,24,24,"difference","greater",0.5),0.5, tolerance=0.001) # x1=n1, x2=n2, pick nullparm carefully expect_equal( pvalue.CI.compatability(12,12,9,24,"difference","greater",-0.1),-0.1, tolerance=0.001) # x1=0, x2=0, pick nullparm carefully expect_equal( pvalue.CI.compatability(0,12,0,24,"difference","greater",-0.1),-0.1, tolerance=0.001) }) test_that("Compatability of p-value and confidence limit (extreme data) - ratio, less", { # ratio # x1=0 and x2=0 gives no information about ratio parameters # so we expect p.value=1, conf.int=(0,Inf) [for ratio] # Estimates= NaN x<- bpcp2samp.nocensoring(0,12,0,24,"ratio","less",1) expect_equal(unname(c(x$p.value,x$conf.int,x$estimate)),c(1,0,Inf,NA)) }) test_that("Compatability of p-value and confidence limit (extreme data) - cdfratio, less", { # cdfratio # x1=n1 and x2=n2 gives no information about cdfratio parameters # so we expect p.value=1, conf.int=(0,Inf) [for cdfratio] # Estimates= NaN x<- bpcp2samp.nocensoring(12,12,24,24,"cdfratio","less",1) expect_equal(unname(c(x$p.value,x$conf.int,x$estimate)),c(1,0,Inf,NA)) }) test_that("Compatability of p-value and confidence limit (extreme data) - logsratio, less", { # logsratio # EITHER x1=n1 and x2=n2 OR x1=0 and x2=0 gives no information # about logsratio parameters # so we expect p.value=1, conf.int=(0,Inf) [for cdfratio] # Estimates= NaN x<- bpcp2samp.nocensoring(12,12,24,24,"logsratio","less",1) expect_equal(unname(c(x$p.value,x$conf.int,x$estimate)),c(1,0,Inf,NA)) x<- bpcp2samp.nocensoring(0,12,0,24,"logsratio","less",1) expect_equal(unname(c(x$p.value,x$conf.int,x$estimate)),c(1,0,Inf,NA)) }) test_that("All CI for twosamp output contain beta estimate, parmtype = difference, melded", { res <- bpcp2samp(time=leuk2$time, status=leuk2$status, group=leuk2$treatment, parmtype = "difference") expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("All CI for twosamp output contain beta estimate, parmtype = difference, melded with midp", { skip_on_cran() res <- bpcp2samp(time=leuk2$time, status=leuk2$status, group=leuk2$treatment, parmtype = "difference", midp = T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("All CI for twosamp output contain beta estimate, parmtype = oddsratio, melded", { res <- bpcp2samp(time=leuk2$time, status=leuk2$status, group=leuk2$treatment, parmtype = "oddsratio", midp = F) expect_true(all(res$lower[!is.na(res$gbeta)] <= res$gbeta[!is.na(res$gbeta)]) & all(res$upper[!is.na(res$gbeta)] >= res$gbeta[!is.na(res$gbeta)])) expect_true(all(res$lower[is.na(res$gbeta)] == 0) & all(res$upper[is.na(res$gbeta)] == Inf)) }) test_that("All CI for twosamp output contain beta estimate, parmtype = oddsratio, melded with midp", { res <- bpcp2samp(time=leuk2$time, status=leuk2$status, group=leuk2$treatment, parmtype = "oddsratio",midp = T, testtime=20) expect_true(all(res$lower[!is.na(res$gbeta)] <= res$gbeta[!is.na(res$gbeta)]) & all(res$upper[!is.na(res$gbeta)] >= res$gbeta[!is.na(res$gbeta)])) expect_true(all(res$lower[is.na(res$gbeta)] == 0) & all(res$upper[is.na(res$gbeta)] == Inf)) }) test_that("All CI for twosamp output contain beta estimate, parmtype = ratio, melded", { res <- bpcp2samp(time=leuk2$time, status=leuk2$status, group=leuk2$treatment, parmtype = "ratio", midp = F) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("All CI for twosamp output contain beta estimate, parmtype = ratio, melded with midp", { skip_on_cran() res <- bpcp2samp(time=leuk2$time, status=leuk2$status, group=leuk2$treatment, parmtype = "ratio", midp = T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("All CI for twosamp output contain beta estimate, parmtype = efflogs, melded", { res <- bpcp2samp(time=leuk2$time, status=leuk2$status, group=leuk2$treatment, parmtype = "efflogs", midp = F) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("All CI for twosamp output contain beta estimate, parmtype = efflogs, melded with midp", { skip_on_cran() res <- bpcp2samp(time=leuk2$time, status=leuk2$status, group=leuk2$treatment, parmtype = "efflogs", midp = T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("All CI for twosamp output contain beta estimate, parmtype = effcdf, melded", { res <- bpcp2samp(time=leuk2$time, status=leuk2$status, group=leuk2$treatment, parmtype = "effcdf", midp = F) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("All CI for twosamp output contain beta estimate, parmtype = effcdf, melded with midp", { skip_on_cran() res <- bpcp2samp(time=leuk2$time, status=leuk2$status, group=leuk2$treatment, parmtype = "effcdf", midp = T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) # S1 = s, S2 = 1 test_that("CI contains beta estimate, parmtype = difference, melded, S1= 1, S2=s", { res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "difference", midp=F) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = difference, melded, S1= s, S2=1", { res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "difference", midp=F, changeGroupOrder=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = difference, melded with midp, S1= 1, S2=s", { skip_on_cran() res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "difference", midp=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = difference, melded with midp, S1= s, S2=1", { skip_on_cran() res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "difference", midp=T, changeGroupOrder=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = ratio, melded, S1= 1, S2=s", { res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "ratio", midp=F) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = ratio, melded, S1= s, S2=1", { res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "ratio", midp=F, changeGroupOrder=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = ratio, melded with midp, S1= 1, S2=s", { skip_on_cran() res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "ratio", midp=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = ratio, melded with midp, S1= s, S2=1", { skip_on_cran() res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "ratio", midp=T, changeGroupOrder=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = oddsratio, melded, S1= 1, S2=s", { res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "oddsratio", midp=F) expect_true(all(res$lower[!is.na(res$gbeta)] <= res$gbeta[!is.na(res$gbeta)]) & all(res$upper[!is.na(res$gbeta)] >= res$gbeta[!is.na(res$gbeta)])) expect_true(all(res$lower[is.na(res$gbeta)] == 0) & all(res$upper[is.na(res$gbeta)] == Inf)) }) test_that("CI contains beta estimate, parmtype = oddsratio, melded, S1= s, S2=1", { res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "oddsratio", midp=F, changeGroupOrder=T) expect_true(all(res$lower[!is.na(res$gbeta)] <= res$gbeta[!is.na(res$gbeta)]) & all(res$upper[!is.na(res$gbeta)] >= res$gbeta[!is.na(res$gbeta)])) expect_true(all(res$lower[is.na(res$gbeta)] == 0) & all(res$upper[is.na(res$gbeta)] == Inf)) }) test_that("CI contains beta estimate, parmtype = oddsratio, melded with midp, S1= 1, S2=s", { skip_on_cran() res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "oddsratio", midp=T) expect_true(all(res$lower[!is.na(res$gbeta)] <= res$gbeta[!is.na(res$gbeta)]) & all(res$upper[!is.na(res$gbeta)] >= res$gbeta[!is.na(res$gbeta)])) expect_true(all(res$lower[is.na(res$gbeta)] == 0) & all(res$upper[is.na(res$gbeta)] == Inf)) }) test_that("CI contains beta estimate, parmtype = oddsratio, melded with midp, S1= s, S2=1", { skip_on_cran() res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "oddsratio", midp=T, changeGroupOrder=T) expect_true(all(res$lower[!is.na(res$gbeta)] <= res$gbeta[!is.na(res$gbeta)]) & all(res$upper[!is.na(res$gbeta)] >= res$gbeta[!is.na(res$gbeta)])) expect_true(all(res$lower[is.na(res$gbeta)] == 0) & all(res$upper[is.na(res$gbeta)] == Inf)) }) test_that("CI contains beta estimate, parmtype = effcdf, melded, S1= 1, S2=s", { res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "effcdf", midp=F) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = effcdf, melded, S1= s, S2=1", { res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "effcdf", midp=F, changeGroupOrder=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = effcdf, melded with midp, S1= 1, S2=s", { skip_on_cran() res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "effcdf", midp=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = effcdf, melded with midp, S1= s, S2=1", { skip_on_cran() res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "effcdf", midp=T, changeGroupOrder=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = efflogs, melded, S1= 1, S2=s", { res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "efflogs", midp=F) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = efflogs, melded, S1= s, S2=1", { res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "efflogs", midp=F, changeGroupOrder=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = efflogs, melded with midp, S1= 1, S2=s", { skip_on_cran() res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "efflogs", midp=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = efflogs, melded with midp, S1= s, S2=1", { skip_on_cran() res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "efflogs", midp=T, changeGroupOrder=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) # S1 = 0, S2 = 1 test_that("CI contains beta estimate, parmtype = difference, melded, S1= 0, S2=1", { res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "difference", midp=F) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = difference, melded, S1= 1, S2=0", { res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "difference", midp=F, changeGroupOrder=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = difference, melded with midp, S1= 0, S2=1", { skip_on_cran() res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "difference", midp=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = difference, melded with midp, S1= 1, S2=0", { skip_on_cran() res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "difference", midp=T, changeGroupOrder=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = ratio, melded, S1= 0, S2=1", { res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "ratio", midp=F) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = ratio, melded, S1= 1, S2=0", { res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "ratio", midp=F, changeGroupOrder=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = ratio, melded with midp, S1= 0, S2=1", { skip_on_cran() res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "ratio", midp=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = ratio, melded with midp, S1= 1, S2=0", { skip_on_cran() res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "ratio", midp=T, changeGroupOrder=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = oddsratio, melded, S1= 0, S2=1", { res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "oddsratio", midp=F) expect_true(all(res$lower[!is.na(res$gbeta)] <= res$gbeta[!is.na(res$gbeta)]) & all(res$upper[!is.na(res$gbeta)] >= res$gbeta[!is.na(res$gbeta)])) expect_true(all(res$lower[is.na(res$gbeta)] == 0) & all(res$upper[is.na(res$gbeta)] == Inf)) }) test_that("CI contains beta estimate, parmtype = oddsratio, melded, S1= 1, S2=0", { res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "oddsratio", midp=F, changeGroupOrder=T) expect_true(all(res$lower[!is.na(res$gbeta)] <= res$gbeta[!is.na(res$gbeta)]) & all(res$upper[!is.na(res$gbeta)] >= res$gbeta[!is.na(res$gbeta)])) expect_true(all(res$lower[is.na(res$gbeta)] == 0) & all(res$upper[is.na(res$gbeta)] == Inf)) }) test_that("CI contains beta estimate, parmtype = oddsratio, melded with midp, S1= 0, S2=1", { skip_on_cran() res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "oddsratio", midp=T) expect_true(all(res$lower[!is.na(res$gbeta)] <= res$gbeta[!is.na(res$gbeta)]) & all(res$upper[!is.na(res$gbeta)] >= res$gbeta[!is.na(res$gbeta)])) expect_true(all(res$lower[is.na(res$gbeta)] == 0) & all(res$upper[is.na(res$gbeta)] == Inf)) }) test_that("CI contains beta estimate, parmtype = oddsratio, melded with midp, S1= 1, S2=0", { skip_on_cran() res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "oddsratio", midp=T, changeGroupOrder=T) expect_true(all(res$lower[!is.na(res$gbeta)] <= res$gbeta[!is.na(res$gbeta)]) & all(res$upper[!is.na(res$gbeta)] >= res$gbeta[!is.na(res$gbeta)])) expect_true(all(res$lower[is.na(res$gbeta)] == 0) & all(res$upper[is.na(res$gbeta)] == Inf)) }) test_that("CI contains beta estimate, parmtype = effcdf, melded, S1= 0, S2=1", { res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "effcdf", midp=F) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = effcdf, melded, S1= 1, S2=0", { res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "effcdf", midp=F, changeGroupOrder=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = effcdf, melded with midp, S1= 0, S2=1", { skip_on_cran() res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "effcdf", midp=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = effcdf, melded with midp, S1= 1, S2=0", { skip_on_cran() res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "effcdf", midp=T, changeGroupOrder=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = efflogs, melded, S1= 0, S2=1", { res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "efflogs", midp=F) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = efflogs, melded, S1= 1, S2=0", { res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "efflogs", midp=F, changeGroupOrder=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = efflogs, melded with midp, S1= 0, S2=1", { skip_on_cran() res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "efflogs", midp=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = efflogs, melded with midp, S1= 1, S2=0", { skip_on_cran() res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "efflogs", midp=T, changeGroupOrder=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) # S1 = s, S2 = 0 test_that("CI contains beta estimate, parmtype = difference, melded, S1= 0, S2=s", { res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "difference", midp=F) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = difference, melded, S1= s, S2=0", { res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "difference", midp=F, changeGroupOrder=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = difference, melded with midp, S1= 0, S2=s", { skip_on_cran() res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "difference", midp=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = difference, melded with midp, S1= s, S2=0", { skip_on_cran() res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "difference", midp=T, changeGroupOrder=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = ratio, melded, S1= 0, S2=s", { res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "ratio", midp=F) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = ratio, melded, S1= s, S2=0", { res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "ratio", midp=F, changeGroupOrder=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = ratio, melded with midp, S1= 0, S2=s", { skip_on_cran() res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "ratio", midp=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = ratio, melded with midp, S1= s, S2=0", { skip_on_cran() res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "ratio", midp=T, changeGroupOrder=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = oddsratio, melded, S1= 0, S2=s", { res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "oddsratio", midp=F) expect_true(all(res$lower[!is.na(res$gbeta)] <= res$gbeta[!is.na(res$gbeta)]) & all(res$upper[!is.na(res$gbeta)] >= res$gbeta[!is.na(res$gbeta)])) expect_true(all(res$lower[is.na(res$gbeta)] == 0) & all(res$upper[is.na(res$gbeta)] == Inf)) }) test_that("CI contains beta estimate, parmtype = oddsratio, melded, S1= s, S2=0", { res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "oddsratio", midp=F, changeGroupOrder=T) expect_true(all(res$lower[!is.na(res$gbeta)] <= res$gbeta[!is.na(res$gbeta)]) & all(res$upper[!is.na(res$gbeta)] >= res$gbeta[!is.na(res$gbeta)])) expect_true(all(res$lower[is.na(res$gbeta)] == 0) & all(res$upper[is.na(res$gbeta)] == Inf)) }) test_that("CI contains beta estimate, parmtype = oddsratio, melded with midp, S1= 0, S2=s", { skip_on_cran() res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "oddsratio", midp=T) expect_true(all(res$lower[!is.na(res$gbeta)] <= res$gbeta[!is.na(res$gbeta)]) & all(res$upper[!is.na(res$gbeta)] >= res$gbeta[!is.na(res$gbeta)])) expect_true(all(res$lower[is.na(res$gbeta)] == 0) & all(res$upper[is.na(res$gbeta)] == Inf)) }) test_that("CI contains beta estimate, parmtype = oddsratio, melded with midp, S1= s, S2=0", { skip_on_cran() res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "oddsratio", midp=T, changeGroupOrder=T) expect_true(all(res$lower[!is.na(res$gbeta)] <= res$gbeta[!is.na(res$gbeta)]) & all(res$upper[!is.na(res$gbeta)] >= res$gbeta[!is.na(res$gbeta)])) expect_true(all(res$lower[is.na(res$gbeta)] == 0) & all(res$upper[is.na(res$gbeta)] == Inf)) }) test_that("CI contains beta estimate, parmtype = effcdf, melded, S1= 0, S2=s", { res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "effcdf", midp=F) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = effcdf, melded, S1= s, S2=0", { res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "effcdf", midp=F, changeGroupOrder=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = effcdf, melded with midp, S1= 0, S2=s", { skip_on_cran() res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "effcdf", midp=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = effcdf, melded with midp, S1= s, S2=0", { skip_on_cran() res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "effcdf", midp=T, changeGroupOrder=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = efflogs, melded, S1= 0, S2=s", { res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "efflogs", midp=F) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = efflogs, melded, S1= s, S2=0", { res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "efflogs", midp=F, changeGroupOrder=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = efflogs, melded with midp, S1= 0, S2=s", { res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "efflogs", midp=T, testtime=7) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("CI contains beta estimate, parmtype = efflogs, melded with midp, S1= s, S2=0", { skip_on_cran() res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "efflogs", midp=T, changeGroupOrder=T) expect_true(all(res$lower <= res$gbeta) & all(res$upper >= res$gbeta)) }) test_that("p-value is between 0 and 1, parmtype = difference, melded, S1= 1, S2=s", { res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "difference", midp=F) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = difference, melded, S1= s, S2=1", { res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "difference", midp=F, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = difference, melded with midp, S1= 1, S2=s", { skip_on_cran() res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "difference", midp=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = difference, melded with midp, S1= s, S2=1", { skip_on_cran() res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "difference", midp=T, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = ratio, melded, S1= 1, S2=s", { res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "ratio", midp=F) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = ratio, melded, S1= s, S2=1", { res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "ratio", midp=F, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = ratio, melded with midp, S1= 1, S2=s", { skip_on_cran() res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "ratio", midp=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = ratio, melded with midp, S1= s, S2=1", { skip_on_cran() res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "ratio", midp=T, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = oddsratio, melded, S1= 1, S2=s", { res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "oddsratio", midp=F) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = oddsratio, melded, S1= s, S2=1", { res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "oddsratio", midp=F, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = oddsratio, melded with midp, S1= 1, S2=s", { skip_on_cran() res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "oddsratio", midp=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = oddsratio, melded with midp, S1= s, S2=1", { skip_on_cran() res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "oddsratio", midp=T, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = effcdf, melded, S1= 1, S2=s", { res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "effcdf", midp=F) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = effcdf, melded, S1= s, S2=1", { res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "effcdf", midp=F, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = effcdf, melded with midp, S1= 1, S2=s", { skip_on_cran() res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "effcdf", midp=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = effcdf, melded with midp, S1= s, S2=1", { skip_on_cran() res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "effcdf", midp=T, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = efflogs, melded, S1= 1, S2=s", { res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "efflogs", midp=F) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = efflogs, melded, S1= s, S2=1", { res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "efflogs", midp=F, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = efflogs, melded with midp, S1= 1, S2=s", { skip_on_cran() res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "efflogs", midp=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = efflogs, melded with midp, S1= s, S2=1", { skip_on_cran() res <- bpcp2samp(time=d_failure$time, status=d_failure$status, group=d_failure$rx, parmtype = "efflogs", midp=T, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) # S1 = 0, S2 = 1 test_that("p-value is between 0 and 1, parmtype = difference, melded, S1= 0, S2=1", { res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "difference", midp=F) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = difference, melded, S1= 1, S2=0", { res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "difference", midp=F, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = difference, melded with midp, S1= 0, S2=1", { skip_on_cran() res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "difference", midp=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = difference, melded with midp, S1= 1, S2=0", { skip_on_cran() res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "difference", midp=T, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = ratio, melded, S1= 0, S2=1", { res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "ratio", midp=F) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = ratio, melded, S1= 1, S2=0", { res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "ratio", midp=F, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = ratio, melded with midp, S1= 0, S2=1", { skip_on_cran() res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "ratio", midp=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = ratio, melded with midp, S1= 1, S2=0", { skip_on_cran() res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "ratio", midp=T, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = oddsratio, melded, S1= 0, S2=1", { res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "oddsratio", midp=F) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = oddsratio, melded, S1= 1, S2=0", { res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "oddsratio", midp=F, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = oddsratio, melded with midp, S1= 0, S2=1", { skip_on_cran() res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "oddsratio", midp=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = oddsratio, melded with midp, S1= 1, S2=0", { skip_on_cran() res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "oddsratio", midp=T, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = effcdf, melded, S1= 0, S2=1", { res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "effcdf", midp=F) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = effcdf, melded, S1= 1, S2=0", { res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "effcdf", midp=F, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = effcdf, melded with midp, S1= 0, S2=1", { skip_on_cran() res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "effcdf", midp=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = effcdf, melded with midp, S1= 1, S2=0", { skip_on_cran() res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "effcdf", midp=T, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = efflogs, melded, S1= 0, S2=1", { res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "efflogs", midp=F) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = efflogs, melded, S1= 1, S2=0", { res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "efflogs", midp=F, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = efflogs, melded with midp, S1= 0, S2=1", { skip_on_cran() res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "efflogs", midp=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = efflogs, melded with midp, S1= 1, S2=0", { skip_on_cran() res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "efflogs", midp=T, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) # S1 = s, S2 = 0 test_that("p-value is between 0 and 1, parmtype = difference, melded, S1= 0, S2=s", { res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "difference", midp=F) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = difference, melded, S1= s, S2=0", { res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "difference", midp=F, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = difference, melded with midp, S1= 0, S2=s", { skip_on_cran() res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "difference", midp=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = difference, melded with midp, S1= s, S2=0", { skip_on_cran() res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "difference", midp=T, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = ratio, melded, S1= 0, S2=s", { res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "ratio", midp=F) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = ratio, melded, S1= s, S2=0", { res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "ratio", midp=F, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = ratio, melded with midp, S1= 0, S2=s", { skip_on_cran() res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "ratio", midp=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = ratio, melded with midp, S1= s, S2=0", { skip_on_cran() res <- bpcp2samp(time=d_failure_2$time, status=d_failure_2$status, group=d_failure_2$rx, parmtype = "ratio", midp=T, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = oddsratio, melded, S1= 0, S2=s", { res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "oddsratio", midp=F) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = oddsratio, melded, S1= s, S2=0", { res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "oddsratio", midp=F, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = oddsratio, melded with midp, S1= 0, S2=s", { skip_on_cran() res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "oddsratio", midp=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = oddsratio, melded with midp, S1= s, S2=0", { skip_on_cran() res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "oddsratio", midp=T, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = effcdf, melded, S1= 0, S2=s", { res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "effcdf", midp=F) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = effcdf, melded, S1= s, S2=0", { res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "effcdf", midp=F, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = effcdf, melded with midp, S1= 0, S2=s", { skip_on_cran() res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "effcdf", midp=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = effcdf, melded with midp, S1= s, S2=0", { skip_on_cran() res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "effcdf", midp=T,changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = efflogs, melded, S1= 0, S2=s", { res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "efflogs", midp=F) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = efflogs, melded, S1= s, S2=0", { res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "efflogs", midp=F, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = efflogs, melded with midp, S1= 0, S2=s", { skip_on_cran() res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "efflogs", midp=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) }) test_that("p-value is between 0 and 1, parmtype = efflogs, melded with midp, S1= s, S2=0", { skip_on_cran() res <- bpcp2samp(time=d_failure_3$time, status=d_failure_3$status, group=d_failure_3$rx, parmtype = "efflogs", midp=T, changeGroupOrder=T) expect_true(all(res$p.value <= 1) & all(res$p.value >= 0)) })