## try to reconstruct error reported by Hofert Jan Marius ## (simpler version) Lfun <- function(x) { (x-5)^2 } library(bbmle) lb <- 6 ## first try with L-BFGS-B and bounds m1 <- mle2(Lfun,start=list(x=7),lower=6,method="L-BFGS-B") coef(m1) p1 <- profile(m1) plot(p1) (c1 <- confint(m1,quietly=TRUE)) ## all OK m2 <- mle2(Lfun,start=list(x=7),optimizer="optimize", lower=lb,upper=10) coef(m2) p2 <- profile(m2) (c2 <- confint(m2)) (c2 <- confint(m2)) plot(p2,show.points=TRUE)