R version 4.5.0 RC (2025-04-04 r88118 ucrt) -- "How About a Twenty-Six"
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> library(WayFindR)

> library(Rgraphviz)
Loading required package: graph
Loading required package: BiocGenerics
Loading required package: generics

Attaching package: 'generics'

The following objects are masked from 'package:base':

    as.difftime, as.factor, as.ordered, intersect, is.element, setdiff,
    setequal, union


Attaching package: 'BiocGenerics'

The following objects are masked from 'package:stats':

    IQR, mad, sd, var, xtabs

The following objects are masked from 'package:base':

    Filter, Find, Map, Position, Reduce, anyDuplicated, aperm, append,
    as.data.frame, basename, cbind, colnames, dirname, do.call,
    duplicated, eval, evalq, get, grep, grepl, is.unsorted, lapply,
    mapply, match, mget, order, paste, pmax, pmax.int, pmin, pmin.int,
    rank, rbind, rownames, sapply, saveRDS, table, tapply, unique,
    unsplit, which.max, which.min

Loading required package: grid
> ## input directly from file
> xmlfile <- system.file("pathways/kegg_hsa00510.xml", package = "WayFindR")
> graf <- KGMLtoIgraph(xmlfile)
Warning message:
In KGMLtoIgraph(xmlfile) : KGML: Some nodes have no edge connections!

> set.seed(24086)
> L <- igraph::layout_with_kk(graf)
> plot(graf, layout = L)
> ## FAILS because of multiple edges:
> try( RA <- as.graphNEL(graf) )
Error in as_graphnel(G) : 
  multiple edges are not supported in graphNEL graphs
> 
> xmlfile <- system.file("pathways/WP3850.gpml", package = "WayFindR")
> G <- GPMLtoIgraph(xmlfile)
> set.seed(13579)
> GN <- as.graphNEL(G)
> plot(GN)
> 
> proc.time()
   user  system elapsed 
  11.39    1.85   17.09