Package check result: NOTE

Check: examples, Result: NOTE
  Examples with CPU time > 2.5 times elapsed time
       user system elapsed ratio
  vmd 1.345  0.016   0.179 7.603

Check: tests, Result: NOTE
    Running ‘testthat.R’ [16s/3s]
  Running R code in ‘testthat.R’ had CPU time 4.8 times elapsed time

No changes to worse in reverse depends.