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> # This file is part of the standard setup for testthat.
> # It is recommended that you do not modify it.
> #
> # Where should you do additional test configuration?
> # Learn more about the roles of various files in:
> # * https://r-pkgs.org/testing-design.html#sec-tests-files-overview
> # * https://testthat.r-lib.org/articles/special-files.html
> 
> library(testthat)
> library(SynergyLMM)
> 
> test_check("SynergyLMM")

Title:
 Shapiro - Wilk Normality Test of random effects

Test Results:
  STATISTIC:
    W: 0.9678
  P VALUE:
    0.8702 


Title:
 Anderson - Darling Normality Test of random effects

Test Results:
  STATISTIC:
    A: 0.1635
  P VALUE:
    0.9172 


Normalized Residuals Levene Homoscedasticity Test by Sample
Levene's Test for Homogeneity of Variance (center = median)
      Df F value Pr(>F)
group  9  0.5417 0.8398
      80               

Normalized Residuals Fligner-Killeen Homoscedasticity Test by Sample

	Fligner-Killeen test of homogeneity of variances

data:  normalized_resid by SampleID
Fligner-Killeen:med chi-squared = 5.1645, df = 9, p-value = 0.8197


Title:
 Shapiro - Wilk Normality Test of random effects

Test Results:
  STATISTIC:
    W: 0.9678
  P VALUE:
    0.8702 


Title:
 Anderson - Darling Normality Test of random effects

Test Results:
  STATISTIC:
    A: 0.1635
  P VALUE:
    0.9172 


Normalized Residuals Levene Homoscedasticity Test by Sample
Levene's Test for Homogeneity of Variance (center = median)
      Df F value Pr(>F)
group  9  0.5417 0.8398
      80               

Normalized Residuals Fligner-Killeen Homoscedasticity Test by Sample

	Fligner-Killeen test of homogeneity of variances

data:  normalized_resid by SampleID
Fligner-Killeen:med chi-squared = 5.1645, df = 9, p-value = 0.8197


Title:
 Shapiro - Wilk Normality Test of random effects

Test Results:
  STATISTIC:
    W: 0.9678
  P VALUE:
    0.8702 


Title:
 Anderson - Darling Normality Test of random effects

Test Results:
  STATISTIC:
    A: 0.1635
  P VALUE:
    0.9172 


Normalized Residuals Levene Homoscedasticity Test by Sample
Levene's Test for Homogeneity of Variance (center = median)
      Df F value Pr(>F)
group  9  0.5417 0.8398
      80               

Normalized Residuals Fligner-Killeen Homoscedasticity Test by Sample

	Fligner-Killeen test of homogeneity of variances

data:  normalized_resid by SampleID
Fligner-Killeen:med chi-squared = 5.1645, df = 9, p-value = 0.8197


Title:
 Shapiro - Wilk Normality Test of random effects

Test Results:
  STATISTIC:
    W: 0.9678
  P VALUE:
    0.8702 


Title:
 Anderson - Darling Normality Test of random effects

Test Results:
  STATISTIC:
    A: 0.1635
  P VALUE:
    0.9172 


Normalized Residuals Levene Homoscedasticity Test by Sample
Levene's Test for Homogeneity of Variance (center = median)
      Df F value Pr(>F)
group  9  0.5417 0.8398
      80               

Normalized Residuals Fligner-Killeen Homoscedasticity Test by Sample

	Fligner-Killeen test of homogeneity of variances

data:  normalized_resid by SampleID
Fligner-Killeen:med chi-squared = 5.1645, df = 9, p-value = 0.8197


Title:
 Shapiro - Wilk Normality Test

Test Results:
  STATISTIC:
    W: 0.7822
  P VALUE:
    3.211e-10 

Description:
 Shapiro - Wilk Normality Test of normalized residuals

Title:
 D'Agostino Normality Test

Test Results:
  STATISTIC:
    Chi2 | Omnibus: 86.0072
    Z3  | Skewness: 6.9361
    Z4  | Kurtosis: 6.1561
  P VALUE:
    Omnibus  Test: < 2.2e-16 
    Skewness Test: 4.029e-12 
    Kurtosis Test: 7.457e-10 

Description:
 D'Agostino Normality Test of normalized residuals

Title:
 Anderson - Darling Normality Test

Test Results:
  STATISTIC:
    A: 2.7744
  P VALUE:
    4.865e-07 

Description:
 Anderson - Darling Normality Test of normalized residuals

Normalized Residuals Levene Homoscedasticity Test by Time
Levene's Test for Homogeneity of Variance (center = median)
      Df F value Pr(>F)
group  8  0.5553 0.8111
      81               

Normalized Residuals Fligner-Killeen Homoscedasticity Test by Time

	Fligner-Killeen test of homogeneity of variances

data:  normalized_resid by as.factor(Time)
Fligner-Killeen:med chi-squared = 5.6845, df = 8, p-value = 0.6825


Normalized Residuals Levene Homoscedasticity Test by Treatment
Levene's Test for Homogeneity of Variance (center = median)
      Df F value Pr(>F)
group  3  0.9028 0.4433
      86               

Normalized Residuals Fligner-Killeen Homoscedasticity Test by Treatment

	Fligner-Killeen test of homogeneity of variances

data:  normalized_resid by Treatment
Fligner-Killeen:med chi-squared = 1.5828, df = 3, p-value = 0.6633

[1] "Outlier observations"
   SampleID Time Treatment   TV      RTV   logRTV      TV0  idx
90       10    9    Drug_A 1000 8.342366 2.121347 119.8701 TRUE

Title:
 Shapiro - Wilk Normality Test

Test Results:
  STATISTIC:
    W: 0.7822
  P VALUE:
    3.211e-10 

Description:
 Shapiro - Wilk Normality Test of normalized residuals

Title:
 D'Agostino Normality Test

Test Results:
  STATISTIC:
    Chi2 | Omnibus: 86.0072
    Z3  | Skewness: 6.9361
    Z4  | Kurtosis: 6.1561
  P VALUE:
    Omnibus  Test: < 2.2e-16 
    Skewness Test: 4.029e-12 
    Kurtosis Test: 7.457e-10 

Description:
 D'Agostino Normality Test of normalized residuals

Title:
 Anderson - Darling Normality Test

Test Results:
  STATISTIC:
    A: 2.7744
  P VALUE:
    4.865e-07 

Description:
 Anderson - Darling Normality Test of normalized residuals

Normalized Residuals Levene Homoscedasticity Test by Time
Levene's Test for Homogeneity of Variance (center = median)
      Df F value Pr(>F)
group  8  0.5553 0.8111
      81               

Normalized Residuals Fligner-Killeen Homoscedasticity Test by Time

	Fligner-Killeen test of homogeneity of variances

data:  normalized_resid by as.factor(Time)
Fligner-Killeen:med chi-squared = 5.6845, df = 8, p-value = 0.6825


Normalized Residuals Levene Homoscedasticity Test by Treatment
Levene's Test for Homogeneity of Variance (center = median)
      Df F value Pr(>F)
group  3  0.9028 0.4433
      86               

Normalized Residuals Fligner-Killeen Homoscedasticity Test by Treatment

	Fligner-Killeen test of homogeneity of variances

data:  normalized_resid by Treatment
Fligner-Killeen:med chi-squared = 1.5828, df = 3, p-value = 0.6633

[1] "Outlier observations"
   SampleID Time Treatment   TV      RTV   logRTV      TV0  idx
90       10    9    Drug_A 1000 8.342366 2.121347 119.8701 TRUE

Title:
 Shapiro - Wilk Normality Test

Test Results:
  STATISTIC:
    W: 0.7822
  P VALUE:
    3.211e-10 

Description:
 Shapiro - Wilk Normality Test of normalized residuals

Title:
 D'Agostino Normality Test

Test Results:
  STATISTIC:
    Chi2 | Omnibus: 86.0072
    Z3  | Skewness: 6.9361
    Z4  | Kurtosis: 6.1561
  P VALUE:
    Omnibus  Test: < 2.2e-16 
    Skewness Test: 4.029e-12 
    Kurtosis Test: 7.457e-10 

Description:
 D'Agostino Normality Test of normalized residuals

Title:
 Anderson - Darling Normality Test

Test Results:
  STATISTIC:
    A: 2.7744
  P VALUE:
    4.865e-07 

Description:
 Anderson - Darling Normality Test of normalized residuals

Normalized Residuals Levene Homoscedasticity Test by Time
Levene's Test for Homogeneity of Variance (center = median)
      Df F value Pr(>F)
group  8  0.5553 0.8111
      81               

Normalized Residuals Fligner-Killeen Homoscedasticity Test by Time

	Fligner-Killeen test of homogeneity of variances

data:  normalized_resid by as.factor(Time)
Fligner-Killeen:med chi-squared = 5.6845, df = 8, p-value = 0.6825


Normalized Residuals Levene Homoscedasticity Test by Treatment
Levene's Test for Homogeneity of Variance (center = median)
      Df F value Pr(>F)
group  3  0.9028 0.4433
      86               

Normalized Residuals Fligner-Killeen Homoscedasticity Test by Treatment

	Fligner-Killeen test of homogeneity of variances

data:  normalized_resid by Treatment
Fligner-Killeen:med chi-squared = 1.5828, df = 3, p-value = 0.6633

[1] "Outlier observations"
   SampleID Time Treatment   TV      RTV   logRTV      TV0  idx
90       10    9    Drug_A 1000 8.342366 2.121347 119.8701 TRUE

Title:
 Shapiro - Wilk Normality Test

Test Results:
  STATISTIC:
    W: 0.7822
  P VALUE:
    3.211e-10 

Description:
 Shapiro - Wilk Normality Test of normalized residuals

Title:
 D'Agostino Normality Test

Test Results:
  STATISTIC:
    Chi2 | Omnibus: 86.0072
    Z3  | Skewness: 6.9361
    Z4  | Kurtosis: 6.1561
  P VALUE:
    Omnibus  Test: < 2.2e-16 
    Skewness Test: 4.029e-12 
    Kurtosis Test: 7.457e-10 

Description:
 D'Agostino Normality Test of normalized residuals

Title:
 Anderson - Darling Normality Test

Test Results:
  STATISTIC:
    A: 2.7744
  P VALUE:
    4.865e-07 

Description:
 Anderson - Darling Normality Test of normalized residuals

Normalized Residuals Levene Homoscedasticity Test by Time
Levene's Test for Homogeneity of Variance (center = median)
      Df F value Pr(>F)
group  8  0.5553 0.8111
      81               

Normalized Residuals Fligner-Killeen Homoscedasticity Test by Time

	Fligner-Killeen test of homogeneity of variances

data:  normalized_resid by as.factor(Time)
Fligner-Killeen:med chi-squared = 5.6845, df = 8, p-value = 0.6825


Normalized Residuals Levene Homoscedasticity Test by Treatment
Levene's Test for Homogeneity of Variance (center = median)
      Df F value Pr(>F)
group  3  0.9028 0.4433
      86               

Normalized Residuals Fligner-Killeen Homoscedasticity Test by Treatment

	Fligner-Killeen test of homogeneity of variances

data:  normalized_resid by Treatment
Fligner-Killeen:med chi-squared = 1.5828, df = 3, p-value = 0.6633

[1] "Outlier observations"
   SampleID Time Treatment   TV      RTV   logRTV      TV0  idx
90       10    9    Drug_A 1000 8.342366 2.121347 119.8701 TRUE
# Indices of model performance

AIC   |  AICc |    BIC | R2 (cond.) | R2 (marg.) |  RMSE | Sigma
----------------------------------------------------------------
3.797 | 4.809 | 18.796 |      0.186 |      0.186 | 0.189 | 0.195
[1] "Outliers with Log Likelihood displacement greater than: 3.212"
       7 
3.284032 
[1] "Outliers with Log Likelihood displacement greater than: 3.577"
      4 
6.55449 
No subject with a log-likelihood displacement greater than 1000
[1] "Outliers with Log Likelihood displacement greater than: 1000"
named numeric(0)
[1] "Outliers with Log Likelihood displacement greater than: -1000"
         1          2          3          4          5          6          7 
0.08258159 2.00421829 3.20399631 1.04719077 0.29520400 1.85948923 3.28403183 
         8          9         10 
1.09210541 0.36262353 0.02277539 
[1] "Outliers with Log Likelihood displacement greater than: 3.212"
       7 
3.284032 
No subject with a Cook's distance greater than 0.508
[1] "Subjects with Cook's distance greater than: 0.508"
named numeric(0)
[1] "Subjects with Cook's distance greater than: -10"
           1            2            3            4            5            6 
0.0061662437 0.2790770304 0.5079021936 0.1434396748 0.0424742823 0.2923484694 
           7            8            9           10 
0.5079021936 0.1434396748 0.0162734579 0.0001541363 
No subject with a Cook's distance greater than 0.508
[1] "Subjects with Cook's distance greater than: 0.508"
named numeric(0)
  numDF denDF      F-value           nc Power
1     1    56 1.232595e-32 1.232595e-32  0.05
  numDF denDF      F-value           nc Power
1     1    56 1.232595e-32 1.232595e-32  0.05
  numDF denDF      F-value           nc Power
1     1    56 1.232595e-32 1.232595e-32  0.05
  numDF denDF    F-value         nc Power
1     1    56 3.7286e-31 3.7286e-31  0.05
  numDF denDF      F-value           nc Power
1     1    56 1.232595e-32 1.232595e-32  0.05
  numDF denDF      F-value           nc Power
1     1    56 1.232595e-32 1.232595e-32  0.05
  numDF denDF      F-value           nc Power
1     1    56 1.232595e-32 1.232595e-32  0.05
`geom_line()`: Each group consists of only one observation.
i Do you need to adjust the group aesthetic?
[ FAIL 0 | WARN 717 | SKIP 0 | PASS 269 ]

[ FAIL 0 | WARN 717 | SKIP 0 | PASS 269 ]
> 
> proc.time()
   user  system elapsed 
 111.70    2.34  114.03