library(data.table) data.table::setDTthreads(1) library(NMdata) context("NMcreateDoses") test_that("Basic",{ fileRef <- "testReference/NMcreateDoses_01.rds" ## simple - ok res <- NMcreateDoses(TIME=0,AMT=10) expect_equal_to_reference(res,fileRef) }) test_that("custom CMT value",{ res1 <- NMcreateDoses(TIME=0,AMT=10) res2 <- NMcreateDoses(TIME=0,AMT=10,CMT=2) res1$CMT <- 2 expect_equal(res1,res2) }) test_that("Expand columns",{ fileRef <- "testReference/NMcreateDoses_02.rds" res <- NMcreateDoses(TIME=c(0,12),AMT=10,CMT=2) expect_equal_to_reference(res,fileRef) }) test_that("makes no sense to expand TIME",{ #expect_error( NMcreateDoses(TIME=c(0),AMT=c(0,10),CMT=2) #) }) test_that("non-unique AMT",{ ## this is due to a bug that once was where AMT would get shortened because it's non-unique fileRef <- "testReference/NMcreateDoses_03.rds" res <- NMcreateDoses(TIME=c(0,1,4,5),AMT=c(2,1,4,2),CMT=c(1,1,2)) expect_equal_to_reference(res,fileRef) }) ## II/ADDL simple example missing ## II/ADDL should only be applied to last event. addl.lastonly ## argument? test_that("II/ADDL",{ fileRef <- "testReference/NMcreateDoses_04.rds" res <- NMcreateDoses(TIME=c(0,12),AMT=10,addl=list(II=12,ADDL=3),CMT=2) expect_equal_to_reference(res,fileRef) }) ### covariates test_that("covariates basics",{ fileRef <- "testReference/NMcreateDoses_05.rds" res <- NMcreateDoses(TIME=c(0),AMT=data.table(DOSE=c(10,50),AMT=c(10,50))) expect_equal_to_reference(res,fileRef) }) test_that("covariates basics 2",{ fileRef <- "testReference/NMcreateDoses_06.rds" res <- NMcreateDoses(TIME=data.table(regimen=c("SD","MD","MD"),TIME=c(0,0,12)),AMT=10,CMT=1) expect_equal_to_reference(res,fileRef) }) ### TODO: covariates not spanning same covariate values. Should not be supported for now. test_that("covariates not spanning same covariate values",{ fileRef <- "testReference/NMcreateDoses_07.rds" res <- NMcreateDoses(TIME=data.table(regimen=c("SD","MD","MD"),TIME=c(0,0,12)),AMT=10,CMT=1,addl=list(II=12,ADDL=3,regimen="MD")) ##res expect_equal_to_reference(res,fileRef) }) test_that("covariates spanning same covariate values",{ ## This looks OK. fileRef <- "testReference/NMcreateDoses_08.rds" res <- NMcreateDoses(TIME=data.table(regimen=c("SD","MD","MD"),TIME=c(0,0,12)),AMT=data.table(AMT=c(10,5),regimen=c("SD","MD")),CMT=1) expect_equal_to_reference(res,fileRef) }) test_that("covariates spanning same covariate values - addl",{ ## This looks OK. fileRef <- "testReference/NMcreateDoses_09.rds" res <- NMcreateDoses(TIME=data.table(regimen=c("SD","MD","MD"),TIME=c(0,0,12)),AMT=10,CMT=1,addl=data.table(II=c(0,0,0,12),ADDL=c(0,0,0,3),regimen=c("SD",rep("MD",3)))) expect_equal_to_reference(res,fileRef) }) test_that("ID as covariate - not supported",{ expect_error( NMcreateDoses(TIME=c(0),AMT=data.table(ID=c(10,50),AMT=c(10,50))) ) }) ## not sure what extra this example is showing ## NMcreateDoses(TIME=data.table(ID=c(1,1,2,2,2),TIME=c(0,1,0,1,4)),AMT=data.table(ID=c(1,1,2,2),AMT=c(2,1,4,2))) test_that("Expanding AMT within a covariate",{ fileRef <- "testReference/NMcreateDoses_10.rds" res <- NMcreateDoses(TIME=c(0,1,4),AMT=data.table(DOSELEVEL=c(1,1,2,2),AMT=c(2,1,4,2))) expect_equal_to_reference(res,fileRef) }) test_that("as.fun",{ fileRef <- "testReference/NMcreateDoses_11.rds" res <- NMcreateDoses(TIME=0,AMT=10) expect_equal_to_reference(res,fileRef) fileRef <- "testReference/NMcreateDoses_12.rds" res <- NMcreateDoses(TIME=0,AMT=10,as.fun=as.data.frame) expect_equal_to_reference(res,fileRef) }) test_that("data.frames accepted",{ res.df <- NMcreateDoses(TIME=c(0),AMT=data.frame(DOSE=c(10,50),AMT=c(10,50))) res.dt <- NMcreateDoses(TIME=c(0),AMT=data.table(DOSE=c(10,50),AMT=c(10,50))) expect_equal(res.df,res.dt) })