## library(devtools) ## load_all() context("flags") test_that("basic",{ pk <- readRDS(file=system.file("examples/data/xgxr2.rds",package="NMdata")) ### two flag tables with different order of the two conditions dt.flags <- fread(text="FLAG,flag,condition 10,Below LLOQ,EVID==0&BLQ==1 100,Negative time,EVID==0&TIME<0") ## add the two different exclusion flags pk <- flagsAssign(pk,tab.flags=dt.flags,subset.data="EVID==0") pk[EVID==1,FLAG:=0] pk[EVID==1,flag:="Dosing"] ### these were addedd to the dsCreate script ## pk[,flag2:=NULL] ## pk[,FLAG2:=NULL] fileRef <- "testReference/flagsAssign_1.rds" expect_equal_to_reference(pk,fileRef) ### and count the two different exclusions ## two obs are discarded due to negative time tab.count <- flagsCount(pk[EVID==0],dt.flags,col.flagn="FLAG",col.flagc="flag") fileRef <- "testReference/flagsCount_1.rds" expect_equal_to_reference(tab.count,fileRef) }) test_that("alternative order",{ pk <- readRDS(file=system.file("examples/data/xgxr2.rds",package="NMdata")) dt.flags2 <- fread(text="FLAG2,flag2,condition 100,Below LLOQ,EVID==0&BLQ==1 10,Negative time,EVID==0&TIME<0") pk <- flagsAssign(pk,tab.flags=dt.flags2,col.flagn="FLAG2",col.flagc="flag2",subset.data="EVID==0") ## pk[EVID==1,FLAG2:=0] ## pk[EVID==1,flag2:="Dosing"] pk <- flagsAssign(pk,col.flagn="FLAG2",col.flagc="flag2",subset.data="EVID==1",flagc.0="Dosing") ## all excluded due to below LLOQ tab.count <- flagsCount(pk[EVID==0],dt.flags2,col.flagn="FLAG2",col.flagc="flag2") fileRef <- "testReference/flagsAssign_2.rds" expect_equal_to_reference(pk,fileRef) fileRef <- "testReference/flagsCount_2.rds" expect_equal_to_reference(tab.count,fileRef) }) test_that("incresing order",{ pk <- readRDS(file=system.file("examples/data/xgxr2.rds",package="NMdata")) dt.flags2 <- fread(text="FLAG2,flag2,condition 100,Below LLOQ,EVID==0&BLQ==1 10,Negative time,EVID==0&TIME<0") pk <- flagsAssign(pk,tab.flags=dt.flags2,col.flagn="FLAG2",col.flagc="flag2",subset.data="EVID==0",flags.increasing=T) pk[EVID==1,FLAG2:=0] pk[EVID==1,flag2:="Dosing"] ## all excluded due to below LLOQ tab.count <- flagsCount(pk[EVID==0],dt.flags2,col.flagn="FLAG2",col.flagc="flag2",flags.increasing=T) fileRef <- "testReference/flagsAssign_3.rds" expect_equal_to_reference(pk,fileRef) fileRef <- "testReference/flagsCount_3.rds" expect_equal_to_reference(tab.count,fileRef) }) test_that("Include EVID==1",{ pk <- readRDS(file=system.file("examples/data/xgxr2.rds",package="NMdata")) dt.flags <- fread(text="FLAG,flag,condition 0,Dosing,EVID==1 100,Below LLOQ,EVID==0&BLQ==1 10,Negative time,EVID==0&TIME<0") expect_error(flagsAssign(pk,tab.flags=dt.flags,flags.increasing=T)) pk <- flagsAssign(pk,tab.flags=dt.flags,flags.increasing=T,subset.data="EVID==0") pk <- flagsAssign(pk,subset.data="EVID==1",flagc.0="Dosing", col.flagn="flagn",col.flagc="flagc") ## all excluded due to below LLOQ tab.count <- flagsCount(pk[EVID==0],dt.flags,col.flagn="FLAG",col.flagc="flag",flags.increasing=T) fileRef <- "testReference/flagsAssign_4.rds" expect_equal_to_reference(pk,fileRef) fileRef <- "testReference/flagsCount_4.rds" expect_equal_to_reference(tab.count,fileRef) }) test_that("A NULL data set",{ pk <- readRDS(file=system.file("examples/data/xgxr2.rds",package="NMdata")) dt.flags <- fread(text="FLAG,flag,condition 0,Dosing,EVID==1 100,Below LLOQ,EVID==0&BLQ==1 10,Negative time,EVID==0&TIME<0") expect_warning(flagsAssign(data=pk[0],tab.flags=dt.flags,flags.increasing=T)) }) test_that("Writing data - data.frames",{ testOut <- "testOutput/flagsCount_5.csv" pk <- readRDS(file=system.file("examples/data/xgxr2.rds",package="NMdata")) pk <- as.data.frame(pk) dt.flags <- read.csv(text="FLAG,flag,condition 0,Dosing,EVID==1 100,Below LLOQ,EVID==0&BLQ==1 10,Negative time,EVID==0&TIME<0") pk <- flagsAssign(pk,tab.flags=dt.flags,flags.increasing=T,subset.data="EVID==0") pk <- flagsAssign(pk,subset.data="EVID==1",flagc.0="Dosing") ## all excluded due to below LLOQ tab.count <- flagsCount(pk[pk$EVID==0,],dt.flags,flags.increasing=T,file=testOut) testRes <- fread(testOut,header=T) fileRef <- "testReference/flagsCount_5.rds" expect_equal_to_reference(testRes,fileRef) }) test_that("count by",{ fileRef <- "testReference/flagsCount_6.rds" pk <- readRDS("testReference/flagsAssign_1.rds") dt.flags <- fread(text="FLAG,flag,condition 10,Below LLOQ,EVID==0&BLQ==1 100,Negative time,EVID==0&TIME<0") ### and count the two different exclusions ## two obs are discarded due to negative time tab.count <- flagsCount(pk[EVID==0],dt.flags,col.flagn="FLAG",col.flagc="flag",by="TRTACT") expect_equal_to_reference(tab.count,fileRef) })