# LUCID - 1 omics, binary outcome test_that("check estimations of LUCID with binary outcome (K = 2)", { G <- sim_data$G[1:500, ] Z <- sim_data$Z[1:500, ] Y <- sim_data$Y_binary[1:500, ] cov <- sim_data$Covariate[1:500, ] # i <- sample(1:2000, 1) i <- 1008 # i <- sample(1:2000, 1) # cat(paste("test1 - seed =", i, "\n")) invisible(capture.output(fit1 <- estimate_lucid(G = G, Z = Z, Y = Y, K = 2, lucid_model = "early", family = "binary", CoY = cov, seed = i, useY = TRUE))) summary(fit1) pars <- fit1 beta_causal <- mean(pars$res_Beta[2, 2:5]) beta_non <- mean(pars$res_Beta[2, 6:10]) mu_causal <- mean(abs(pars$res_Mu[1, 1:5] - pars$res_Mu[2, 1:5])) mu_non <- mean(abs(pars$res_Mu[1, 6:10] - pars$res_Mu[2, 6:10])) gamma <- as.numeric(pars$res_Gamma$beta) # check parameters expect_equal(beta_causal, log(2), tolerance = 0.2) expect_equal(beta_non, 0, tolerance = 0.1) expect_equal(mu_causal, 2, tolerance = 0.1) expect_equal(mu_non, 0, tolerance = 0.1) expect_equal(gamma, c(-0.5, 0.9, 0.8, -0.8), tolerance = 0.2) # check summary_lucid sum_fit1 <- summary(fit1) expect_equal(class(fit1), "early_lucid") expect_equal(class(sum_fit1), "sumlucid_early") }) test_that("check variable selection on G", { # run LUCID model G <- sim_data$G[1:500, ] Z <- sim_data$Z[1:500, ] Y_binary <- sim_data$Y_binary[1:500, ] cov <- sim_data$Covariate[1:500, ] # i <- sample(1:2000, 1) # cat(paste("test2 - seed =", i, "\n")) i <- 1008 invisible(capture.output(fit1 <- lucid(G = G, Z = Z, Y = Y_binary, CoY = cov, family = "binary", lucid_model = "early", K = 2, seed = i, useY = TRUE, Rho_G = 0.1))) # check parameters expect_equal(class(fit1$select$selectG), "logical") expect_equal(as.vector(fit1$select$selectG), rep(TRUE, 4)) }) test_that("check variable selection on Z", { # run LUCID model G <- sim_data$G[1:500, ] Z <- sim_data$Z[1:500, ] Y_binary <- sim_data$Y_binary[1:500, ] cov <- sim_data$Covariate[1:500, ] # i <- sample(1:2000, 1) # cat(paste("test3 - seed =", i, "\n")) i <- 1008 invisible(capture.output(fit1 <- lucid(G = G, Z = Z, Y = Y_binary, CoY = cov, family = "binary", lucid_model = "early", K = 2, seed = i, useY = TRUE, Rho_Z_Mu = 50, Rho_Z_Cov = 0.5))) # check parameters expect_equal(class(fit1$select$selectZ), "logical") }) test_that("check whether arguments of lucid work", { G <- sim_data$G[1:500, ] Z <- sim_data$Z[1:500, ] Y_binary <- sim_data$Y_binary[1:500, ] cov <- sim_data$Covariate[1:500, ] # i <- sample(1:2000, 1) # cat(paste("test4 - seed =", i, "\n")) i <- 1008 invisible(capture.output(fit1 <- lucid(G = G, Z = Z, Y = Y_binary, CoY = cov, family = "binary", lucid_model = "early", K = 2, seed = i, useY = TRUE, init_omic.data.model = NULL))) invisible(capture.output(fit2 <- lucid(G = G, Z = Z, Y = Y_binary, CoY = cov, family = "binary", lucid_model = "early", K = 2, seed = i, useY = TRUE, init_omic.data.model = "EEV", init_par = "random"))) expect_equal(class(fit1$init_omic.data.model), "character") expect_equal(fit2$init_par, "random") }) test_that("check whether lucid throws an erorr with continuous outcome or outcome coded rather than 0 and 1", { G <- sim_data$G[1:500, ] Z <- sim_data$Z[1:500, ] Y_binary <- sim_data$Y_binary[1:500, ] Y_normal <- sim_data$Y_normal[1:500, ] cov <- sim_data$Covariate[1:500, ] # i <- sample(1:2000, 1) i <- 1008 # cat(paste("test4 - seed =", i, "\n")) expect_error(est_lucid(G = G, Z = Z, Y = Y_normal, CoY = cov, family = "binary", lucid_model = "early", K = 2, seed = i, useY = TRUE, init_omic.data.model = NULL)) expect_error(est_lucid(G = G, Z = Z, Y = Y_binary + 1, CoY = cov, family = "binary", lucid_model = "early", K = 2, seed = i, useY = TRUE, init_omic.data.model = NULL)) })