test_that("eunomia test - some empty cohorts", { db <- DBI::dbConnect(duckdb::duckdb(), dbdir = CDMConnector::eunomia_dir() ) cdm <- CDMConnector::cdm_from_con( con = db, cdm_schema = "main", write_schema = "main" ) # outcome cohorts celecoxib_codes <- dplyr::tibble("concept_id" = c(1118084)) diclofenac_codes <- dplyr::tibble("concept_id" = c(1124300)) # celecoxib cdm$celecoxib <- cdm$drug_era %>% dplyr::inner_join( celecoxib_codes %>% dplyr::select(concept_id), by = c("drug_concept_id" = "concept_id"), copy = TRUE ) %>% dplyr::rename( "subject_id" = "person_id", "cohort_start_date" = "drug_era_start_date", "cohort_end_date" = "drug_era_end_date" ) %>% dplyr::mutate(cohort_definition_id = 1L) %>% dplyr::select( "cohort_definition_id", "subject_id", "cohort_start_date", "cohort_end_date" ) %>% dplyr::compute() # diclofenac cdm$diclofenac <- cdm$drug_era %>% dplyr::inner_join( diclofenac_codes %>% dplyr::select(concept_id), by = c("drug_concept_id" = "concept_id"), copy = TRUE ) %>% dplyr::rename( "subject_id" = "person_id", "cohort_start_date" = "drug_era_start_date", "cohort_end_date" = "drug_era_end_date" ) %>% dplyr::mutate(cohort_definition_id = 2L) %>% dplyr::select( "cohort_definition_id", "subject_id", "cohort_start_date", "cohort_end_date" ) %>% dplyr::compute() cdm$exposure_cohort <- dplyr::union_all( cdm$celecoxib, cdm$diclofenac ) %>% dplyr::compute() cdm$outcome_cohort <- CDMConnector::newGeneratedCohortSet(cdm$exposure_cohort) cdm$outcome_cohort <- addCohortCountAttr(cdm$outcome_cohort) # denominator cdm <- generateDenominatorCohortSet(cdm, name = "denominator", cohortDateRange = c( as.Date("2000-01-01"), as.Date("2020-01-01") ), sex = c("Male", "Female") ) inc <- estimateIncidence( cdm = cdm, denominatorTable = "denominator", outcomeTable = "outcome_cohort", interval = "years" ) expect_true(nrow(inc) > 0) prev <- estimatePeriodPrevalence( cdm = cdm, denominatorTable = "denominator", outcomeTable = "outcome_cohort", interval = "years" ) expect_true(nrow(prev) > 0) plotIncidence(inc, facet = c("outcome_cohort_name", "denominator_sex"), colour = "denominator_sex", colour_name = "Sex" ) plotPrevalence(prev, facet = c("outcome_cohort_name", "denominator_sex"), colour = "denominator_sex", colour_name = "Sex" ) }) test_that("eunomia test - strata", { # Update to your database details as appropriate here db <- DBI::dbConnect(duckdb::duckdb(), dbdir = CDMConnector::eunomia_dir() ) cdm <- CDMConnector::cdm_from_con( con = db, cdm_schema = "main", write_schema = "main" ) asthma_cohort1 <- Capr::cohort(entry = Capr::entry( Capr::conditionOccurrence(Capr::cs(Capr::descendants(317009), name ="asthma")), primaryCriteriaLimit = "First" )) asthma_cohort2 <- Capr::cohort(entry = Capr::entry( Capr::conditionOccurrence( Capr::cs(Capr::descendants(317009), name ="asthma"), Capr::age(Capr::gte(18)) ), primaryCriteriaLimit = "First" )) path1 <- file.path(tempdir(), "outcome") dir.create(path1) Capr::writeCohort(asthma_cohort1, file.path(path1, "asthma_cohort1.json")) path2 <- file.path(tempdir(), "strata") dir.create(path2) Capr::writeCohort(asthma_cohort2, file.path(path2, "asthma_cohort2.json")) outcome_cohort_set <- CDMConnector::readCohortSet(path = path1) cdm <- CDMConnector::generateCohortSet( cdm, outcome_cohort_set, name = "outcome", computeAttrition = TRUE, overwrite = TRUE ) strata_cohort_set <- CDMConnector::readCohortSet(path = path2) cdm <- CDMConnector::generateCohortSet( cdm, strata_cohort_set, name = "strata", computeAttrition = TRUE, overwrite = TRUE ) cdm$dpop <- generateDenominatorCohortSet(cdm, name ="dpop", targetCohortTable = "strata" ) inc <- estimateIncidence( cdm = cdm, denominatorTable = "dpop", outcomeTable = "asthma", targetCohortTable = "target", interval = "years" ) expect_true(nrow(inc) > 0) prev <- estimatePointPrevalence( cdm = cdm, denominatorTable = "dpop", outcomeTable = "asthma", interval = "years" ) expect_true(nrow(prev) > 0) }) test_that("eunomia test - participants", { db <- DBI::dbConnect(duckdb::duckdb(), dbdir = CDMConnector::eunomia_dir() ) cdm <- CDMConnector::cdm_from_con( con = db, cdm_schema = "main", write_schema = "main" ) cdm$dpop <- generateDenominatorCohortSet(cdm) asthma_cohort <- Capr::cohort(entry = Capr::entry( Capr::condition(Capr::cs(Capr::descendants(317009))), primaryCriteriaLimit = "First" )) path <- file.path(tempdir(), "asthma_cohorts_participants") dir.create(path) Capr::writeCohort(asthma_cohort, file.path(path, "asthma_cohort.json")) asthma_cohort_set <- CDMConnector::readCohortSet(path = path) cdm <- CDMConnector::generateCohortSet( cdm, asthma_cohort_set, name = "asthma", computeAttrition = TRUE, overwrite = TRUE ) inc <- estimateIncidence( cdm = cdm, denominatorTable = "dpop", outcomeTable = "asthma", interval = "years", returnParticipants = TRUE, tablePrefix = "test_inc" ) expect_true(nrow(inc) > 0) participants(inc, 1) prev <- estimatePointPrevalence( cdm = cdm, denominatorTable = "dpop", outcomeTable = "asthma", interval = "years" ) expect_true(nrow(prev) > 0) })