require(DoE.base)
set.seed(9890)
plan <- oa.design(nlevels=c(2,6,2), replications=2, repeat.only=TRUE)
y <- rnorm(24)
plan <- reptowide(add.response(plan,y))
aggregate(plan)

plan <- param.design(oa.design(nlevels=c(2,6,2), factor.names=c("C1","C2","C3")), oa.design(ID=L4.2.3))
y <- rnorm(48)
plan <- paramtowide(add.response(plan,y))
aggregate(plan)
aggregate(plan,response="y")

plan <- param.design(oa.design(nlevels=c(2,6,2), factor.names=c("C1","C2","C3")), oa.design(ID=L4.2.3))
plan <- paramtowide(plan)
aggregate(plan)

plan <- cross.design(oa.design(nlevels=c(2,6,2), factor.names=c("C1","C2","C3")), oa.design(ID=L4.2.3,replications=2,repeat.only=TRUE))
y <- rnorm(96)
plan <- reptowide(add.response(plan,y))
aggregate(plan)
aggregate(plan,response="y",FUN=sd)