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Type 'q()' to quit R. > # This file is part of the standard setup for testthat. > # It is recommended that you do not modify it. > # > # Where should you do additional test configuration? > # Learn more about the roles of various files in: > # * https://r-pkgs.org/tests.html > # * https://testthat.r-lib.org/reference/test_package.html#special-files > > library(testthat) > library(Colossus) > > test_check("Colossus") Note: Starting Censoring weight Plot Function Note: 901 risk groups Saving 7 x 7 in image 153.499294651964 Note: Starting Plot Function Note: Getting Plot Info Note: 2 risk groups Note: 2 risk groups Note: Starting Plot Function Note: Getting Plot Info Error: no events Note: Starting Plot Function Note: Getting Plot Info Note: 2 risk groups Error: Plot type not given Note: Starting Plot Function Note: Getting Plot Info Note: 2 risk groups Error: Stratification Column not in dataframe Note: Starting Plot Function Note: Getting Plot Info Note: 2 risk groups Error: Stratification Column not given Note: Starting Plot Function Note: Getting Plot Info Note: 2 risk groups Error: dose column not given Note: Starting Plot Function Note: Getting Plot Info Note: 2 risk groups Error: dose column not given Note: Starting Plot Function Note: Getting Plot Info Note: 2 risk groups Error: ID column is not in the dataframe Note: Starting Plot Function Note: Getting Plot Info Note: 2 risk groups Error: ID column not given Note: Starting Plot Function Note: Getting Plot Info Note: 3 risk groups Note: 3 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:05 2024 C++ Note: Term checked 0 C++ Note: df99,25,Starting C++ Note: Current Time, Tue Feb 13 22:47:05 2024 C++ Note: Grouping Start C++ Note: df100 97 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:05 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 C++ Note: sums checked 3.91896 C++ Note: derivs checked 21.9591 C++ Note: second derivs checked 138.335 C++ Note: dose checked 7 C++ Note: non-dose checked 3.91896 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 3.91896 C++ Note: risk checked 3.91896 C++ Note: risk1 checked 21.9591 C++ Note: risk2 checked 138.335 C++ Note: Made Risk Side Lists C++ Note: riskr checked 1.84393 C++ Note: risk1r checked 8.73121 C++ Note: risk2r checked 46.1633 C++ Note: riskl checked 1.84393 C++ Note: risk1l checked 8.73121 C++ Note: risk2l checked 46.1633 C++ Note: df101 0 C++ Note: df102 0 C++ Note: df103 0 C++ Note: df104 -0.1 C++ Note: df105 nan C++ Note: df106 nan C++ Note: riskr checked 1.84393 C++ Note: risk1r checked 8.73121 C++ Note: risk2r checked 46.1633 C++ Note: riskl checked 1.84393 C++ Note: risk1l checked 8.73121 C++ Note: risk2l checked 46.1633 C++ Note: df101 0 C++ Note: df102 0 C++ Note: df103 0 C++ Note: df104 -0.1 C++ Note: df105 nan C++ Note: df106 nan C++ Note: ending guess 0 C++ Note: df501 0 C++ Note: df504 -0.1 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1, 0<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.1 C++ Note: sums checked 3.91896 C++ Note: derivs checked 21.9591 C++ Note: second derivs checked 138.335 C++ Note: dose checked 7 C++ Note: non-dose checked 3.91896 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 3.91896 C++ Note: risk checked 3.91896 C++ Note: risk1 checked 21.9591 C++ Note: risk2 checked 138.335 C++ Note: Made Risk Side Lists C++ Note: riskr checked 1.84393 C++ Note: risk1r checked 8.73121 C++ Note: risk2r checked 46.1633 C++ Note: riskl checked 1.84393 C++ Note: risk1l checked 8.73121 C++ Note: risk2l checked 46.1633 C++ Note: df101 0 C++ Note: df102 0 C++ Note: df103 0 C++ Note: df104 -0.1 C++ Note: df105 nan C++ Note: df106 nan C++ Note: riskr checked 1.84393 C++ Note: risk1r checked 8.73121 C++ Note: risk2r checked 46.1633 C++ Note: riskl checked 1.84393 C++ Note: risk1l checked 8.73121 C++ Note: risk2l checked 46.1633 C++ Note: df101 0 C++ Note: df102 0 C++ Note: df103 0 C++ Note: df104 -0.1 C++ Note: df105 nan C++ Note: df106 nan C++ Note: Exiting Regression C++ Note: df501 0 C++ Note: df504 -0.1 Note: starting ph_plot Note: nonStratified survival curve calculation C++ Note: START_PLOT C++ Note: Current Time, Tue Feb 13 22:47:05 2024 C++ Note: Term checked 0 C++ Note: df99,21,Starting C++ Note: Current Time, Tue Feb 13 22:47:05 2024 C++ Note: values checked -0.1 C++ Note: sums checked 3.91896 C++ Note: derivs checked 21.9591 C++ Note: second derivs checked 138.335 C++ Note: dose checked 7 C++ Note: non-dose checked 3.91896 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 3.91896 C++ Note: risk checked 3.91896 C++ Note: risk1 checked 21.9591 C++ Note: risk2 checked 138.335 C++ Note: Grouping Start C++ Note: df100 325 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:05 2024 C++ Note: Made Risk Side Lists C++ Note: riskr checked 1.84393 C++ Note: risk1r checked 8.73121 C++ Note: risk2r checked 46.1633 C++ Note: riskl checked 1.84393 C++ Note: risk1l checked 8.73121 C++ Note: risk2l checked 46.1633 C++ Note: df101 0 C++ Note: df102 0 C++ Note: df103 0 C++ Note: df104 -0.1 C++ Note: df105 nan C++ Note: df106 nan Note: writing survival data Note: Plotting Survival Curves Saving 7 x 7 in image Saving 7 x 7 in image Saving 7 x 7 in image Saving 7 x 7 in image Note: Starting Plot Function Note: Getting Plot Info Note: 3 risk groups Note: 3 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:06 2024 C++ Note: Term checked 0 C++ Note: df99,25,Starting C++ Note: Current Time, Tue Feb 13 22:47:06 2024 C++ Note: Grouping Start C++ Note: df100 129 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:06 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 C++ Note: sums checked 3.91896 C++ Note: derivs checked 21.9591 C++ Note: second derivs checked 138.335 C++ Note: dose checked 7 C++ Note: non-dose checked 3.91896 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 3.91896 C++ Note: risk checked 3.91896 C++ Note: risk1 checked 21.9591 C++ Note: risk2 checked 138.335 C++ Note: Made Risk Side Lists C++ Note: riskr checked 7.11207 C++ Note: risk1r checked 41.5001 C++ Note: risk2r checked 269.583 C++ Note: riskl checked 2.29326 C++ Note: risk1l checked 12.3258 C++ Note: risk2l checked 74.9204 C++ Note: df101 -5.824 C++ Note: df102 -0.705933 C++ Note: df103 -15.0512 C++ Note: df104 -0.1 C++ Note: df105 0.046902 C++ Note: df106 8.25007 C++ Note: riskr checked 7.11207 C++ Note: risk1r checked 41.5001 C++ Note: risk2r checked 269.583 C++ Note: riskl checked 2.29326 C++ Note: risk1l checked 12.3258 C++ Note: risk2l checked 74.9204 C++ Note: df101 -5.824 C++ Note: df102 -0.705933 C++ Note: df103 -15.0512 C++ Note: df104 -0.1 C++ Note: df105 0.046902 C++ Note: df106 8.25007 C++ Note: ending guess 0 C++ Note: df501 -5.823998 C++ Note: df504 -0.1 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1, -5.823998<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.1 C++ Note: sums checked 3.91896 C++ Note: derivs checked 21.9591 C++ Note: second derivs checked 138.335 C++ Note: dose checked 7 C++ Note: non-dose checked 3.91896 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 3.91896 C++ Note: risk checked 3.91896 C++ Note: risk1 checked 21.9591 C++ Note: risk2 checked 138.335 C++ Note: Made Risk Side Lists C++ Note: riskr checked 7.11207 C++ Note: risk1r checked 41.5001 C++ Note: risk2r checked 269.583 C++ Note: riskl checked 2.29326 C++ Note: risk1l checked 12.3258 C++ Note: risk2l checked 74.9204 C++ Note: df101 -5.824 C++ Note: df102 -0.705933 C++ Note: df103 -15.0512 C++ Note: df104 -0.1 C++ Note: df105 0.046902 C++ Note: df106 8.25007 C++ Note: riskr checked 7.11207 C++ Note: risk1r checked 41.5001 C++ Note: risk2r checked 269.583 C++ Note: riskl checked 2.29326 C++ Note: risk1l checked 12.3258 C++ Note: risk2l checked 74.9204 C++ Note: df101 -5.824 C++ Note: df102 -0.705933 C++ Note: df103 -15.0512 C++ Note: df104 -0.1 C++ Note: df105 0.046902 C++ Note: df106 8.25007 C++ Note: Exiting Regression C++ Note: df501 -5.823998 C++ Note: df504 -0.1 Note: starting ph_plot Note: Stratified survival curve calculation Note: 2 strata used Note: 2 strata used Note: 3 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:06 2024 C++ Note: Term checked 0 C++ Note: df99,22,Starting C++ Note: Current Time, Tue Feb 13 22:47:06 2024 C++ Note: Grouping Start C++ Note: df100 111 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:06 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 C++ Note: sums checked 3.91896 C++ Note: derivs checked 21.9591 C++ Note: second derivs checked 138.335 C++ Note: dose checked 7 C++ Note: non-dose checked 3.91896 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 3.91896 C++ Note: risk checked 3.91896 C++ Note: risk1 checked 21.9591 C++ Note: risk2 checked 138.335 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2.2112 3.88777 C++ Note: riskl checked 1.05586 1.2374 C++ Note: df101 -3.56531 C++ Note: df102 0.377208 C++ Note: df103 -10.9514 C++ Note: df104 -0.1 C++ Note: df105 -0.0344437 C++ Note: df106 -9.45185 C++ Note: riskr checked 2.2112 3.88777 C++ Note: riskl checked 1.05586 1.2374 C++ Note: df101 -3.56531 C++ Note: df102 0.377208 C++ Note: df103 -10.9514 C++ Note: df104 -0.1 C++ Note: df105 -0.0344437 C++ Note: df106 -9.45185 C++ Note: ending guess 0 C++ Note: df501 -3.56531 C++ Note: df504 -0.1 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1, -3.56531<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.1 C++ Note: sums checked 3.91896 C++ Note: derivs checked 21.9591 C++ Note: second derivs checked 138.335 C++ Note: dose checked 7 C++ Note: non-dose checked 3.91896 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 3.91896 C++ Note: risk checked 3.91896 C++ Note: risk1 checked 21.9591 C++ Note: risk2 checked 138.335 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2.2112 3.88777 C++ Note: riskl checked 1.05586 1.2374 C++ Note: df101 -3.56531 C++ Note: df102 0.377208 C++ Note: df103 -10.9514 C++ Note: df104 -0.1 C++ Note: df105 -0.0344437 C++ Note: df106 -9.45185 C++ Note: riskr checked 2.2112 3.88777 C++ Note: riskl checked 1.05586 1.2374 C++ Note: df101 -3.56531 C++ Note: df102 0.377208 C++ Note: df103 -10.9514 C++ Note: df104 -0.1 C++ Note: df105 -0.0344437 C++ Note: df106 -9.45185 C++ Note: Exiting Regression C++ Note: df501 -3.56531 C++ Note: df504 -0.1 Note: Starting Stratification: Calculation C++ Note: START_PLOT C++ Note: Current Time, Tue Feb 13 22:47:06 2024 C++ Note: Term checked 0 C++ Note: df99,22,Starting C++ Note: Current Time, Tue Feb 13 22:47:06 2024 C++ Note: values checked -0.1 C++ Note: sums checked 3.91896 C++ Note: derivs checked 21.9591 C++ Note: second derivs checked 138.335 C++ Note: dose checked 7 C++ Note: non-dose checked 3.91896 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 3.91896 C++ Note: risk checked 3.91896 C++ Note: risk1 checked 21.9591 C++ Note: risk2 checked 138.335 C++ Note: Grouping Start C++ Note: df100 321 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:06 2024 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2.2112 3.88777 C++ Note: riskl checked 1.05586 1.2374 C++ Note: df101 -3.56531 C++ Note: df102 0.377208 C++ Note: df103 -10.9514 C++ Note: df104 -0.1 C++ Note: df105 -0.0344437 C++ Note: df106 -9.45185 Note: Starting Stratification calculation 1 Note: Starting Stratification calculation 2 Saving 7 x 7 in image Note: Starting Plot Function Note: Getting Plot Info Note: 3 risk groups Note: 3 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:06 2024 C++ Note: Term checked 0 C++ Note: df99,24,Starting C++ Note: Current Time, Tue Feb 13 22:47:06 2024 C++ Note: Grouping Start C++ Note: df100 87 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:06 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 C++ Note: sums checked 3.91896 C++ Note: derivs checked 21.9591 C++ Note: second derivs checked 138.335 C++ Note: dose checked 7 C++ Note: non-dose checked 3.91896 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 3.91896 C++ Note: risk checked 3.91896 C++ Note: risk1 checked 21.9591 C++ Note: risk2 checked 138.335 C++ Note: Made Risk Side Lists C++ Note: riskr checked 1.84393 C++ Note: risk1r checked 8.73121 C++ Note: risk2r checked 46.1633 C++ Note: riskl checked 1.84393 C++ Note: risk1l checked 8.73121 C++ Note: risk2l checked 46.1633 C++ Note: df101 0 C++ Note: df102 0 C++ Note: df103 0 C++ Note: df104 -0.1 C++ Note: df105 nan C++ Note: df106 nan C++ Note: riskr checked 1.84393 C++ Note: risk1r checked 8.73121 C++ Note: risk2r checked 46.1633 C++ Note: riskl checked 1.84393 C++ Note: risk1l checked 8.73121 C++ Note: risk2l checked 46.1633 C++ Note: df101 0 C++ Note: df102 0 C++ Note: df103 0 C++ Note: df104 -0.1 C++ Note: df105 nan C++ Note: df106 nan C++ Note: ending guess 0 C++ Note: df501 0 C++ Note: df504 -0.1 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1, 0<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.1 C++ Note: sums checked 3.91896 C++ Note: derivs checked 21.9591 C++ Note: second derivs checked 138.335 C++ Note: dose checked 7 C++ Note: non-dose checked 3.91896 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 3.91896 C++ Note: risk checked 3.91896 C++ Note: risk1 checked 21.9591 C++ Note: risk2 checked 138.335 C++ Note: Made Risk Side Lists C++ Note: riskr checked 1.84393 C++ Note: risk1r checked 8.73121 C++ Note: risk2r checked 46.1633 C++ Note: riskl checked 1.84393 C++ Note: risk1l checked 8.73121 C++ Note: risk2l checked 46.1633 C++ Note: df101 0 C++ Note: df102 0 C++ Note: df103 0 C++ Note: df104 -0.1 C++ Note: df105 nan C++ Note: df106 nan C++ Note: riskr checked 1.84393 C++ Note: risk1r checked 8.73121 C++ Note: risk2r checked 46.1633 C++ Note: riskl checked 1.84393 C++ Note: risk1l checked 8.73121 C++ Note: risk2l checked 46.1633 C++ Note: df101 0 C++ Note: df102 0 C++ Note: df103 0 C++ Note: df104 -0.1 C++ Note: df105 nan C++ Note: df106 nan C++ Note: Exiting Regression C++ Note: df501 0 C++ Note: df504 -0.1 C++ Note: START_PLOT C++ Note: Current Time, Tue Feb 13 22:47:06 2024 C++ Note: Term checked 0 C++ Note: df99,76,Starting C++ Note: Current Time, Tue Feb 13 22:47:06 2024 C++ Note: values checked -0.1 C++ Note: sums checked 5.29005 C++ Note: dose checked 7 C++ Note: non-dose checked 5.29005 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 5.29005 C++ Note: risk checked 5.29005 Saving 7 x 7 in image Note: Starting Plot Function Note: Getting Plot Info Note: 86 risk groups Note: 86 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:06 2024 C++ Note: Term checked 0 1 C++ Note: df99,28,Starting C++ Note: Current Time, Tue Feb 13 22:47:06 2024 C++ Note: Grouping Start C++ Note: df100 1383 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:06 2024 C++ Note: starting subterms 2 in guess 0 C++ Note: values checked 0.01 -15 C++ Note: sums checked 6437.95 3328 C++ Note: derivs checked 3813.95 0.000939732 C++ Note: second derivs checked 3813.95 0.000939732 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6437.95 3328 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6437.95 3328 C++ Note: risk checked 9787.82 C++ Note: risk1 checked 6011.82 0.000944651 C++ Note: risk2 checked 6011.82 0.000944651 C++ Note: Made Risk Side Lists C++ Note: riskr checked 6489.99 C++ Note: risk1r checked 4018.99 0.000575324 C++ Note: risk2r checked 4018.99 0.000575324 C++ Note: riskl checked 119.492 C++ Note: risk1l checked 49.4925 1.62651e-05 C++ Note: risk2l checked 49.4925 1.62651e-05 C++ Note: df101 -329.891 -329.891 C++ Note: df102 -21.7852 9.27193e-06 C++ Note: df103 -19.521 9.27193e-06 C++ Note: df104 0.01 -15 C++ Note: df105 1.11599 1 C++ Note: df106 15.1429 -3.55796e+07 C++ Note: riskr checked 6489.99 C++ Note: risk1r checked 4018.99 0.000575324 C++ Note: risk2r checked 4018.99 0.000575324 C++ Note: riskl checked 119.492 C++ Note: risk1l checked 49.4925 1.62651e-05 C++ Note: risk2l checked 49.4925 1.62651e-05 C++ Note: df101 -329.891 -329.891 C++ Note: df102 -21.7852 9.27193e-06 C++ Note: df103 -19.521 9.27193e-06 C++ Note: df104 0.01 -15 C++ Note: df105 1.11599 1 C++ Note: df106 15.1429 -3.55796e+07 C++ Note: ending guess 0 C++ Note: df501 -329.8914 C++ Note: df504 0.01 -15 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.01 -15, -329.8914<-- Best Guess C++ Note: starting subterms 2 in best guess 0 C++ Note: values checked 0.01 -15 C++ Note: sums checked 6437.95 3328 C++ Note: derivs checked 3813.95 0.000939732 C++ Note: second derivs checked 3813.95 0.000939732 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6437.95 3328 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6437.95 3328 C++ Note: risk checked 9787.82 C++ Note: risk1 checked 6011.82 0.000944651 C++ Note: risk2 checked 6011.82 0.000944651 C++ Note: Made Risk Side Lists C++ Note: riskr checked 6489.99 C++ Note: risk1r checked 4018.99 0.000575324 C++ Note: risk2r checked 4018.99 0.000575324 C++ Note: riskl checked 119.492 C++ Note: risk1l checked 49.4925 1.62651e-05 C++ Note: risk2l checked 49.4925 1.62651e-05 C++ Note: df101 -329.891 -329.891 C++ Note: df102 -21.7852 9.27193e-06 C++ Note: df103 -19.521 9.27193e-06 C++ Note: df104 0.01 -15 C++ Note: df105 1.11599 1 C++ Note: df106 15.1429 -3.55796e+07 C++ Note: riskr checked 6489.99 C++ Note: risk1r checked 4018.99 0.000575324 C++ Note: risk2r checked 4018.99 0.000575324 C++ Note: riskl checked 119.492 C++ Note: risk1l checked 49.4925 1.62651e-05 C++ Note: risk2l checked 49.4925 1.62651e-05 C++ Note: df101 -329.891 -329.891 C++ Note: df102 -21.7852 9.27193e-06 C++ Note: df103 -19.521 9.27193e-06 C++ Note: df104 0.01 -15 C++ Note: df105 1.11599 1 C++ Note: df106 15.1429 -3.55796e+07 C++ Note: Exiting Regression C++ Note: df501 -329.8914 C++ Note: df504 0.01 -15 Note: 86 risk groups C++ Note: START_PLOT C++ Note: Current Time, Tue Feb 13 22:47:06 2024 C++ Note: Term checked 0 1 C++ Note: df99,31,Starting C++ Note: Current Time, Tue Feb 13 22:47:06 2024 C++ Note: values checked 0.01 -15 C++ Note: sums checked 6437.95 3328 C++ Note: derivs checked 3813.95 0.000939732 C++ Note: second derivs checked 3813.95 0.000939732 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6437.95 3328 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6437.95 3328 C++ Note: risk checked 9787.82 C++ Note: risk1 checked 6011.82 0.000944651 C++ Note: risk2 checked 6011.82 0.000944651 C++ Note: Grouping Start C++ Note: df100 2599 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:06 2024 C++ Note: Made Risk Side Lists C++ Note: riskr checked 6489.99 C++ Note: risk1r checked 4018.99 0.000575324 C++ Note: risk2r checked 4018.99 0.000575324 C++ Note: riskl checked 119.492 C++ Note: risk1l checked 49.4925 1.62651e-05 C++ Note: risk2l checked 49.4925 1.62651e-05 C++ Note: df101 -329.891 -329.891 C++ Note: df102 -21.7852 9.27193e-06 C++ Note: df103 -19.521 9.27193e-06 C++ Note: df104 0.01 -15 C++ Note: df105 1.11599 1 C++ Note: df106 15.1429 -3.55796e+07 C++ Note: starting plot data Saving 7 x 7 in image Saving 7 x 7 in image Saving 7 x 7 in image Saving 7 x 7 in image Note: Starting Plot Function Note: Getting Plot Info Note: 2 risk groups Note: 2 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:07 2024 C++ Note: Term checked 0 C++ Note: df99,24,Starting C++ Note: Current Time, Tue Feb 13 22:47:07 2024 C++ Note: Grouping Start C++ Note: df100 91 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:07 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 C++ Note: sums checked 3.91896 C++ Note: derivs checked 21.9591 C++ Note: second derivs checked 138.335 C++ Note: dose checked 7 C++ Note: non-dose checked 3.91896 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 3.91896 C++ Note: risk checked 3.91896 C++ Note: risk1 checked 21.9591 C++ Note: risk2 checked 138.335 C++ Note: Made Risk Side Lists C++ Note: riskr checked 1.11965 C++ Note: risk1r checked 6.27591 C++ Note: risk2r checked 39.4822 C++ Note: riskl checked 1.11965 C++ Note: risk1l checked 6.27591 C++ Note: risk2l checked 39.4822 C++ Note: df101 0 C++ Note: df102 0 C++ Note: df103 0 C++ Note: df104 -0.1 C++ Note: df105 nan C++ Note: df106 nan C++ Note: riskr checked 1.11965 C++ Note: risk1r checked 6.27591 C++ Note: risk2r checked 39.4822 C++ Note: riskl checked 1.11965 C++ Note: risk1l checked 6.27591 C++ Note: risk2l checked 39.4822 C++ Note: df101 0 C++ Note: df102 0 C++ Note: df103 0 C++ Note: df104 -0.1 C++ Note: df105 nan C++ Note: df106 nan C++ Note: ending guess 0 C++ Note: df501 0 C++ Note: df504 -0.1 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1, 0<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.1 C++ Note: sums checked 3.91896 C++ Note: derivs checked 21.9591 C++ Note: second derivs checked 138.335 C++ Note: dose checked 7 C++ Note: non-dose checked 3.91896 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 3.91896 C++ Note: risk checked 3.91896 C++ Note: risk1 checked 21.9591 C++ Note: risk2 checked 138.335 C++ Note: Made Risk Side Lists C++ Note: riskr checked 1.11965 C++ Note: risk1r checked 6.27591 C++ Note: risk2r checked 39.4822 C++ Note: riskl checked 1.11965 C++ Note: risk1l checked 6.27591 C++ Note: risk2l checked 39.4822 C++ Note: df101 0 C++ Note: df102 0 C++ Note: df103 0 C++ Note: df104 -0.1 C++ Note: df105 nan C++ Note: df106 nan C++ Note: riskr checked 1.11965 C++ Note: risk1r checked 6.27591 C++ Note: risk2r checked 39.4822 C++ Note: riskl checked 1.11965 C++ Note: risk1l checked 6.27591 C++ Note: risk2l checked 39.4822 C++ Note: df101 0 C++ Note: df102 0 C++ Note: df103 0 C++ Note: df104 -0.1 C++ Note: df105 nan C++ Note: df106 nan C++ Note: Exiting Regression C++ Note: df501 0 C++ Note: df504 -0.1 Note: starting ph_plot Note: nonStratified survival curve calculation C++ Note: START_PLOT C++ Note: Current Time, Tue Feb 13 22:47:07 2024 C++ Note: Term checked 0 C++ Note: df99,21,Starting C++ Note: Current Time, Tue Feb 13 22:47:07 2024 C++ Note: values checked -0.1 C++ Note: sums checked 3.91896 C++ Note: derivs checked 21.9591 C++ Note: second derivs checked 138.335 C++ Note: dose checked 7 C++ Note: non-dose checked 3.91896 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 3.91896 C++ Note: risk checked 3.91896 C++ Note: risk1 checked 21.9591 C++ Note: risk2 checked 138.335 C++ Note: Grouping Start C++ Note: df100 314 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:07 2024 C++ Note: Made Risk Side Lists C++ Note: riskr checked 1.11965 C++ Note: risk1r checked 6.27591 C++ Note: risk2r checked 39.4822 C++ Note: riskl checked 1.11965 C++ Note: risk1l checked 6.27591 C++ Note: risk2l checked 39.4822 C++ Note: df101 0 C++ Note: df102 0 C++ Note: df103 0 C++ Note: df104 -0.1 C++ Note: df105 nan C++ Note: df106 nan Note: writing survival data Note: Plotting Martingale Residuals Note: Martingale Plot: d Saving 7 x 7 in image Saving 7 x 7 in image Note: Starting Plot Function Note: Getting Plot Info Note: 3 risk groups Note: 3 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:08 2024 C++ Note: Term checked 0 C++ Note: df99,25,Starting C++ Note: Current Time, Tue Feb 13 22:47:08 2024 C++ Note: Grouping Start C++ Note: df100 104 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:08 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 C++ Note: sums checked 3.91896 C++ Note: derivs checked 21.9591 C++ Note: second derivs checked 138.335 C++ Note: dose checked 7 C++ Note: non-dose checked 3.91896 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 3.91896 C++ Note: risk checked 3.91896 C++ Note: risk1 checked 21.9591 C++ Note: risk2 checked 138.335 C++ Note: Made Risk Side Lists C++ Note: riskr checked 1.84393 C++ Note: risk1r checked 8.73121 C++ Note: risk2r checked 46.1633 C++ Note: riskl checked 1.84393 C++ Note: risk1l checked 8.73121 C++ Note: risk2l checked 46.1633 C++ Note: df101 0 C++ Note: df102 0 C++ Note: df103 0 C++ Note: df104 -0.1 C++ Note: df105 nan C++ Note: df106 nan C++ Note: riskr checked 1.84393 C++ Note: risk1r checked 8.73121 C++ Note: risk2r checked 46.1633 C++ Note: riskl checked 1.84393 C++ Note: risk1l checked 8.73121 C++ Note: risk2l checked 46.1633 C++ Note: df101 0 C++ Note: df102 0 C++ Note: df103 0 C++ Note: df104 -0.1 C++ Note: df105 nan C++ Note: df106 nan C++ Note: ending guess 0 C++ Note: df501 0 C++ Note: df504 -0.1 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1, 0<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.1 C++ Note: sums checked 3.91896 C++ Note: derivs checked 21.9591 C++ Note: second derivs checked 138.335 C++ Note: dose checked 7 C++ Note: non-dose checked 3.91896 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 3.91896 C++ Note: risk checked 3.91896 C++ Note: risk1 checked 21.9591 C++ Note: risk2 checked 138.335 C++ Note: Made Risk Side Lists C++ Note: riskr checked 1.84393 C++ Note: risk1r checked 8.73121 C++ Note: risk2r checked 46.1633 C++ Note: riskl checked 1.84393 C++ Note: risk1l checked 8.73121 C++ Note: risk2l checked 46.1633 C++ Note: df101 0 C++ Note: df102 0 C++ Note: df103 0 C++ Note: df104 -0.1 C++ Note: df105 nan C++ Note: df106 nan C++ Note: riskr checked 1.84393 C++ Note: risk1r checked 8.73121 C++ Note: risk2r checked 46.1633 C++ Note: riskl checked 1.84393 C++ Note: risk1l checked 8.73121 C++ Note: risk2l checked 46.1633 C++ Note: df101 0 C++ Note: df102 0 C++ Note: df103 0 C++ Note: df104 -0.1 C++ Note: df105 nan C++ Note: df106 nan C++ Note: Exiting Regression C++ Note: df501 0 C++ Note: df504 -0.1 Note: starting ph_plot Note: nonStratified survival curve calculation C++ Note: START_PLOT C++ Note: Current Time, Tue Feb 13 22:47:08 2024 C++ Note: Term checked 0 C++ Note: df99,22,Starting C++ Note: Current Time, Tue Feb 13 22:47:08 2024 C++ Note: values checked -0.1 C++ Note: sums checked 3.91896 C++ Note: derivs checked 21.9591 C++ Note: second derivs checked 138.335 C++ Note: dose checked 7 C++ Note: non-dose checked 3.91896 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 3.91896 C++ Note: risk checked 3.91896 C++ Note: risk1 checked 21.9591 C++ Note: risk2 checked 138.335 C++ Note: Grouping Start C++ Note: df100 320 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:08 2024 C++ Note: Made Risk Side Lists C++ Note: riskr checked 1.84393 C++ Note: risk1r checked 8.73121 C++ Note: risk2r checked 46.1633 C++ Note: riskl checked 1.84393 C++ Note: risk1l checked 8.73121 C++ Note: risk2l checked 46.1633 C++ Note: df101 0 C++ Note: df102 0 C++ Note: df103 0 C++ Note: df104 -0.1 C++ Note: df105 nan C++ Note: df106 nan Note: writing survival data Note: Plotting Survival Curves Saving 7 x 7 in image Saving 7 x 7 in image Saving 7 x 7 in image Saving 7 x 7 in image Note: Plotting Kaplan-Meier Curve Saving 7 x 7 in image Saving 7 x 7 in image Saving 7 x 7 in image Error: Cores Requested: 196 , Cores Available: 2 Warning: a and e are equal Warning: a and e are equal Warning: b and f are equal Warning: a and d are equal Warning: a and f are equal Warning: a and b are equal Warning: a and c are equal Warning: a and b are equal Warning: a and c are equal Warning: a and b are equal Warning: a and c are equal Error: e not in data.table Error: e not in data.table Error: Iteration: a?+?b?+c has incorrect length of 4 but should be 3. Error: Incorrect operation of ++ Error: Terms used: 2 , Terms with gmix types available: 1 Error: Model formula FAILING_CHOICE not in acceptable list Error: Model formula MA not in acceptable list Error: Model formula EA not in acceptable list Note: Number of factors:1 Note: Number of factors:7 Error: a0 arguement was negative Error: a0 arguement was not a number Error: a0 arguement was not a number Error: a0 arguement was negative Error: a0 arguement was not a number Error: a0 arguement was not a number Error: a0 arguement was not a number Error: goal is too low Error: a0 arguement was negative Error: e missing from column names Error: The missing-value replacement is also NA Note: Column b had replaced values Note: Column b had replaced values Warning: Parameters used: 4, Covariates used: 5, Remaining filled with 0.01 Error: Atleast one parameter must be free Error: Parameters used: 6, Covariates used: 5 Error: Terms used: 4, Covariates used: 5 Error: Terms used: 6, Covariates used: 5 Error: Term types used: 4, Covariates used: 5 Error: Term types used: 6, Covariates used: 5 Error: lin_int missing Error: step_int missing Error: loglin_top missing Error: lin_quad_int missing Error: lin_exp_int missing Error: lin_exp_exp_slope missing Error: step_slope missing Error: lin_slope missing Error: lin_quad_slope missing Error: lin_exp_slope missing Error: lin_exp_int missing Error: Parameters used in first option: 5, Parameters used in different option: 4, please fix parameter length Warning: Parameters used: 4, Covariates used: 5, Remaining filled with 0.01 Error: Parameters used: 6, Covariates used: 5 Error: Terms used: 4, Covariates used: 5 Error: Terms used: 6, Covariates used: 5 Error: Term types used: 4, Covariates used: 5 Error: Term types used: 6, Covariates used: 5 Error: verbosity arguement not valid Error: verbosity arguement not valid Error: verbosity arguement not valid C++ Error: A non-positive risk was detected: -0.3510469 C++ Warning: final failing values -0.1 -0.1 6 0.1 C++ Warning: final failing terms loglin lin_exp_slope lin_exp_int lin_exp_exp_slope C++ Error: A non-positive risk was detected: -0.3510469 C++ Warning: final failing values -0.1 -0.1 6 0.1 C++ Warning: final failing terms loglin lin_exp_slope lin_exp_int lin_exp_exp_slope Error: Default Parameters used: 7, Covariates used: 4 Error: Terms used: 1, Covariates used: 4 Error: Terms used: 8, Covariates used: 4 Error: Term types used: 1, Covariates used: 4 Error: Term types used: 5, Covariates used: 4 C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 1 1 2 C++ Note: df99,38,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 3 C++ Note: values checked -0.75 0.1 -0.05 -1.5 C++ Note: sums checked 4.889466 -2.95 -2.95 1 C++ Note: dose checked 7 7 7 C++ Note: non-dose checked 4.889466 -2.95 1 C++ Note: LIN_non-dose checked 7 -2.95 7 C++ Note: PLIN_non-dose checked 7 7 1 C++ Note: LOGLIN_non-dose checked 4.889466 7 7 C++ Note: df99,340,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 Note: 2 risk groups C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 1 1 2 C++ Note: df99,37,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 3 C++ Note: values checked 0.1 0.1 0.1 0.1 C++ Note: sums checked 7.420684 8.15 8.15 7.4 C++ Note: dose checked 7 7 7 C++ Note: non-dose checked 7.420684 8.15 7.4 C++ Note: LIN_non-dose checked 7 8.15 7 C++ Note: PLIN_non-dose checked 7 7 7.4 C++ Note: LOGLIN_non-dose checked 7.420684 7 7 C++ Note: df99,453,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 Warning: rmin and rmax lists not equal size, defaulting to lin and loglin min/max values C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,33,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 1 C++ Note: values checked -0.1 6 0.1 0.1 C++ Note: sums checked 6.978181e+23 6.978181e+23 6.978181e+23 6.978181e+23 C++ Note: dose checked 7 C++ Note: non-dose checked 6.978181e+23 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 6.978181e+23 C++ Note: df99,252,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 Note: 1 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,33,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 1 C++ Note: values checked 0.3463916 6.304159 0.8865509 -0.5078236 C++ Note: sums checked 2.987966e+27 2.987966e+27 2.987966e+27 2.987966e+27 C++ Note: dose checked 7 C++ Note: non-dose checked 2.987966e+27 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 2.987966e+27 C++ Note: df99,254,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 Note: 2 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,32,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 1 C++ Note: values checked -1.055012 5.321686 -0.2539159 -0.5270897 C++ Note: sums checked 4.342821e+13 4.342821e+13 4.342821e+13 4.342821e+13 C++ Note: dose checked 7 C++ Note: non-dose checked 4.342821e+13 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 4.342821e+13 C++ Note: df99,228,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 Note: 3 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,32,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 1 C++ Note: values checked -0.9390471 5.14898 0.610929 -0.2954936 C++ Note: sums checked 4.929584e+17 4.929584e+17 4.929584e+17 4.929584e+17 C++ Note: dose checked 7 C++ Note: non-dose checked 4.929584e+17 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 4.929584e+17 C++ Note: df99,226,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 Note: 4 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,31,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 1 C++ Note: values checked 0.02965728 6.148232 -0.2576523 -0.2959716 C++ Note: sums checked 9.657357e+21 9.657357e+21 9.657357e+21 9.657357e+21 C++ Note: dose checked 7 C++ Note: non-dose checked 9.657357e+21 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 9.657357e+21 C++ Note: df99,223,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 Note: 5 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,32,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 1 C++ Note: values checked 0.8817955 5.748313 -0.5653119 0.9611492 C++ Note: sums checked 2.899688e+27 2.899688e+27 2.899688e+27 2.899688e+27 C++ Note: dose checked 7 C++ Note: non-dose checked 2.899688e+27 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 2.899688e+27 C++ Note: df99,222,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 Note: 6 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,31,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 1 C++ Note: values checked -0.1773757 5.238308 -0.03229803 -0.1473524 C++ Note: sums checked 1.20929e+19 1.20929e+19 1.20929e+19 1.20929e+19 C++ Note: dose checked 7 C++ Note: non-dose checked 1.20929e+19 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 1.20929e+19 C++ Note: df99,222,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 Note: 7 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,32,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 1 C++ Note: values checked 0.8213166 5.341693 0.2306454 0.7587236 C++ Note: sums checked 9.046649e+27 9.046649e+27 9.046649e+27 9.046649e+27 C++ Note: dose checked 7 C++ Note: non-dose checked 9.046649e+27 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 9.046649e+27 C++ Note: df99,226,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 Note: 8 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,31,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 1 C++ Note: values checked -0.4641113 6.277177 0.7796233 -0.3538364 C++ Note: sums checked 2.434113e+24 2.434113e+24 2.434113e+24 2.434113e+24 C++ Note: dose checked 7 C++ Note: non-dose checked 2.434113e+24 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 2.434113e+24 C++ Note: df99,220,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 Note: 9 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,31,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 1 C++ Note: values checked -0.5852596 5.510797 -0.03075315 0.4470143 C++ Note: sums checked 7.608655e+20 7.608655e+20 7.608655e+20 7.608655e+20 C++ Note: dose checked 7 C++ Note: non-dose checked 7.608655e+20 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 7.608655e+20 C++ Note: df99,222,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,32,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 1 C++ Note: values checked -0.1 6 0.1 0.1 C++ Note: sums checked 6.978181e+23 6.978181e+23 6.978181e+23 6.978181e+23 C++ Note: dose checked 7 C++ Note: non-dose checked 6.978181e+23 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 6.978181e+23 C++ Note: df99,228,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 Note: 1 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,31,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 1 C++ Note: values checked -0.08915908 5.808318 0.1892626 0.1354332 C++ Note: sums checked 4.210637e+23 4.210637e+23 4.210637e+23 4.210637e+23 C++ Note: dose checked 7 C++ Note: non-dose checked 4.210637e+23 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 4.210637e+23 C++ Note: df99,226,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 Note: 2 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,31,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 1 C++ Note: values checked -0.06496972 6.455593 0.03796181 0.1663003 C++ Note: sums checked 5.993695e+25 5.993695e+25 5.993695e+25 5.993695e+25 C++ Note: dose checked 7 C++ Note: non-dose checked 5.993695e+25 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 5.993695e+25 C++ Note: df99,226,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 Note: 3 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,31,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 1 C++ Note: values checked -0.1937416 5.861664 0.08200692 0.1611141 C++ Note: sums checked 1.274614e+23 1.274614e+23 1.274614e+23 1.274614e+23 C++ Note: dose checked 7 C++ Note: non-dose checked 1.274614e+23 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 1.274614e+23 C++ Note: df99,225,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 Note: 4 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,31,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 1 C++ Note: values checked -0.07780974 6.327792 0.1760995 0.1145414 C++ Note: sums checked 3.678198e+25 3.678198e+25 3.678198e+25 3.678198e+25 C++ Note: dose checked 7 C++ Note: non-dose checked 3.678198e+25 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 3.678198e+25 C++ Note: df99,219,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 Note: 5 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,31,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 1 C++ Note: values checked -0.01309711 6.281693 0.1393961 0.1139665 C++ Note: sums checked 3.109525e+25 3.109525e+25 3.109525e+25 3.109525e+25 C++ Note: dose checked 7 C++ Note: non-dose checked 3.109525e+25 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 3.109525e+25 C++ Note: df99,224,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 Note: 6 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,31,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 1 C++ Note: values checked -0.1417443 6.942747 0.03165205 0.1885921 C++ Note: sums checked 2.779633e+27 2.779633e+27 2.779633e+27 2.779633e+27 C++ Note: dose checked 7 C++ Note: non-dose checked 2.779633e+27 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 2.779633e+27 C++ Note: df99,221,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 Note: 7 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,31,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 1 C++ Note: values checked -0.167514 6.683374 0.1683035 0.1548359 C++ Note: sums checked 5.391644e+26 5.391644e+26 5.391644e+26 5.391644e+26 C++ Note: dose checked 7 C++ Note: non-dose checked 5.391644e+26 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 5.391644e+26 C++ Note: df99,224,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 Note: 8 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,32,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 1 C++ Note: values checked -0.1299841 6.285999 0.06202282 0.1055695 C++ Note: sums checked 5.218524e+24 5.218524e+24 5.218524e+24 5.218524e+24 C++ Note: dose checked 7 C++ Note: non-dose checked 5.218524e+24 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 5.218524e+24 C++ Note: df99,223,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 Note: 9 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,32,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 1 C++ Note: values checked -0.1411534 6.070634 0.1104979 0.1611518 C++ Note: sums checked 1.733531e+24 1.733531e+24 1.733531e+24 1.733531e+24 C++ Note: dose checked 7 C++ Note: non-dose checked 1.733531e+24 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 1.733531e+24 C++ Note: df99,227,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 Error: tform not implemented bad_bad Error: der_iden should be within 0:(length(Term_n)-1) Error: der_iden should be within 0:(length(Term_n)-1) Error: Constraint matrix has incorrect number of columns Error: Constraint rows and constant lengths do not match Error: verbosity arguement not valid Warning: model covariate order changed C++ Note: START_POIS_GUESS C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 1 2 C++ Note: df99,30,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 3 in guess 0 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1236.65 1236.65 1016.5 C++ Note: derivs checked 2747.26 2747.26 1673.67 C++ Note: second derivs checked 8496.71 8496.71 4753.83 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1236.65 1236.65 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1236.65 1236.65 1016.5 C++ Note: risk checked 4052.81 C++ Note: risk1 checked 9299.71 3760.02 2068.63 C++ Note: risk2 checked 29099.4 11966.6 5880.84 C++ Note: df101 -4519.7 -4519.7 -4519.7 C++ Note: df102 -10345.4 -4185.29 -2253.92 C++ Note: df103 -33061.5 -13457 -6485.44 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 8811.4 C++ Note: df105 0.312914 0.311011 0.347535 C++ Note: df106 0.436879 1.0799 2.00526 C++ Note: Starting Halves C++ Note: df501 -4519.699 C++ Note: df504 0.1 0.1 0.01 C++ Note: values checked -0.134685 -0.133258 -0.250651 C++ Note: sums checked 774.868 776.82 703.489 C++ Note: derivs checked 1365.53 1371.12 844.007 C++ Note: second derivs checked 3905.39 3923.41 2041.17 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 774.868 776.82 703.489 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 774.868 776.82 703.489 C++ Note: risk checked 1942.91 C++ Note: risk1 checked 3268.5 941.63 654.931 C++ Note: risk2 checked 9221.32 2558.93 1581.01 C++ Note: df101 -2210.36 -2210.36 -2210.36 C++ Note: df102 -3502.58 -1006.4 -684.849 C++ Note: df103 -10472.8 -2780.5 -1683.69 C++ Note: df104 -0.134685 -0.133258 -0.250651 C++ Note: Checking Deviance 4192.72 C++ Note: df105 0.334446 0.36195 0.406754 C++ Note: df106 0.631065 2.19629 3.22751 C++ Note: df100 2428 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 2477 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -2210.358 -2210.358 -2210.358 C++ Note: df102 -3502.582 -1006.405 -684.8491 C++ Note: df103 -10472.79 -2780.504 -1683.693 C++ Note: df104 -0.1346854 -0.1332584 -0.250651 C++ Note: Checking Deviance 4192.716 C++ Note: df105 0.334446 0.3619505 0.4067542 C++ Note: df106 0.6310653 2.196291 3.227511 C++ Note: df101 -2210.36 -2210.36 -2210.36 C++ Note: df102 -3502.58 -1006.4 -684.849 C++ Note: df103 -10472.8 -2780.5 -1683.69 C++ Note: df104 -0.134685 -0.133258 -0.250651 C++ Note: Checking Deviance 4192.72 C++ Note: df105 0.334446 0.36195 0.406754 C++ Note: df106 0.631065 2.19629 3.22751 C++ Note: ending guess 0 C++ Note: df501 -2210.358 C++ Note: df504 -0.1346854 -0.1332584 -0.250651 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1346854 -0.1332584 -0.250651, -2210.358<-- Best Guess C++ Note: starting subterms 3 in best guess 0 C++ Note: values checked -0.134685 -0.133258 -0.250651 C++ Note: sums checked 774.868 776.82 703.489 C++ Note: derivs checked 1365.53 1371.12 844.007 C++ Note: second derivs checked 3905.39 3923.41 2041.17 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 774.868 776.82 703.489 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 774.868 776.82 703.489 C++ Note: risk checked 1942.91 C++ Note: risk1 checked 3268.5 941.63 654.931 C++ Note: risk2 checked 9221.32 2558.93 1581.01 C++ Note: Made Risk Side Lists C++ Note: df101 -2210.36 -2210.36 -2210.36 C++ Note: df102 -3502.58 -1006.4 -684.849 C++ Note: df103 -10472.8 -2780.5 -1683.69 C++ Note: df104 -0.134685 -0.133258 -0.250651 C++ Note: Checking Deviance 4192.72 C++ Note: df105 0.334446 0.36195 0.406754 C++ Note: df106 0.631065 2.19629 3.22751 C++ Note: Starting Halves C++ Note: df501 -2210.358 C++ Note: df504 -0.1346854 -0.1332584 -0.250651 C++ Note: values checked -0.38552 -0.404721 -0.555717 C++ Note: sums checked 528.141 515.228 517.859 C++ Note: derivs checked 689.283 655.992 432.017 C++ Note: second derivs checked 1784.33 1684.27 857.748 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 528.141 515.228 517.859 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 528.141 515.228 517.859 C++ Note: risk checked 1152.34 C++ Note: risk1 checked 1309.58 264.296 229.776 C++ Note: risk2 checked 3285.26 569.511 452.602 C++ Note: df101 -1392.54 -1392.54 -1392.54 C++ Note: df102 -1280.84 -260.607 -224.444 C++ Note: df103 -3733.28 -562.787 -452.582 C++ Note: df104 -0.38552 -0.404721 -0.555717 C++ Note: Checking Deviance 2557.08 C++ Note: df105 0.343087 0.463066 0.495919 C++ Note: df106 1.08721 5.34345 6.20441 C++ Note: df100 5155 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 5203 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -1392.542 -1392.542 -1392.542 C++ Note: df102 -1280.841 -260.6072 -224.4437 C++ Note: df103 -3733.28 -562.7866 -452.5817 C++ Note: df104 -0.3855199 -0.4047212 -0.5557166 C++ Note: Checking Deviance 2557.083 C++ Note: df105 0.3430874 0.4630657 0.4959186 C++ Note: df106 1.087209 5.34345 6.204414 C++ Note: df101 -1392.54 -1392.54 -1392.54 C++ Note: df102 -1280.84 -260.607 -224.444 C++ Note: df103 -3733.28 -562.787 -452.582 C++ Note: df104 -0.38552 -0.404721 -0.555717 C++ Note: Checking Deviance 2557.08 C++ Note: df105 0.343087 0.463066 0.495919 C++ Note: df106 1.08721 5.34345 6.20441 C++ Note: df501 -1392.542 C++ Note: df504 -0.3855199 -0.4047212 -0.5557166 Error: Atleast one parameter must be free Warning: model covariate order changed Error: no events Warning: model covariate order changed C++ Note: START_POIS_GUESS C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 1 2 C++ Note: df99,30,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 3 in guess 0 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1105.17 1236.65 1016.5 C++ Note: derivs checked 1105.17 2747.26 1673.67 C++ Note: second derivs checked 1105.17 8496.71 4753.83 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1105.17 1236.65 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1105.17 1236.65 1016.5 C++ Note: risk checked 3595.28 C++ Note: risk1 checked 3595.28 3036.19 1849.69 C++ Note: risk2 checked 3595.28 9390.32 5253.79 C++ Note: df101 -4008.71 -4008.71 -4008.71 C++ Note: df102 -3951.98 -3362.4 -2006.91 C++ Note: df103 -4065.98 -10523.3 -5775.48 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 7789.42 C++ Note: df105 0.971963 0.319519 0.347489 C++ Note: df106 1.01435 1.19222 1.99745 C++ Note: Starting Halves C++ Note: df501 -4008.71 C++ Note: df504 0.1 0.1 0.01 C++ Note: values checked -0.628972 -0.13964 -0.250617 C++ Note: sums checked 533.14 768.15 703.518 C++ Note: derivs checked 533.14 1346.34 844.078 C++ Note: second derivs checked 533.14 3843.51 2041.39 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 533.14 768.15 703.518 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 533.14 768.15 703.518 C++ Note: risk checked 1317.74 C++ Note: risk1 checked 1317.74 717.785 450.011 C++ Note: risk2 checked 1317.74 2049.13 1088.34 C++ Note: df101 -1549.12 -1549.12 -1549.12 C++ Note: df102 -1377.03 -753.296 -455.699 C++ Note: df103 -1491.03 -2204.79 -1131.21 C++ Note: df104 -0.628972 -0.13964 -0.250617 C++ Note: Checking Deviance 2870.24 C++ Note: df105 0.923543 0.341663 0.402843 C++ Note: df106 1.12497 2.05646 3.39944 C++ Note: df100 2210 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 2258 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -1549.12 -1549.12 -1549.12 C++ Note: df102 -1377.031 -753.2956 -455.6985 C++ Note: df103 -1491.031 -2204.789 -1131.205 C++ Note: df104 -0.6289719 -0.1396396 -0.2506166 C++ Note: Checking Deviance 2870.239 C++ Note: df105 0.9235428 0.3416633 0.4028433 C++ Note: df106 1.124971 2.056456 3.399439 C++ Note: df101 -1549.12 -1549.12 -1549.12 C++ Note: df102 -1377.03 -753.296 -455.699 C++ Note: df103 -1491.03 -2204.79 -1131.21 C++ Note: df104 -0.628972 -0.13964 -0.250617 C++ Note: Checking Deviance 2870.24 C++ Note: df105 0.923543 0.341663 0.402843 C++ Note: df106 1.12497 2.05646 3.39944 C++ Note: ending guess 0 C++ Note: df501 -1549.12 C++ Note: df504 -0.6289719 -0.1396396 -0.2506166 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.6289719 -0.1396396 -0.2506166, -1549.12<-- Best Guess C++ Note: starting subterms 3 in best guess 0 C++ Note: values checked -0.628972 -0.13964 -0.250617 C++ Note: sums checked 533.14 768.15 703.518 C++ Note: derivs checked 533.14 1346.34 844.078 C++ Note: second derivs checked 533.14 3843.51 2041.39 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 533.14 768.15 703.518 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 533.14 768.15 703.518 C++ Note: risk checked 1317.74 C++ Note: risk1 checked 1317.74 717.785 450.011 C++ Note: risk2 checked 1317.74 2049.13 1088.34 C++ Note: Made Risk Side Lists C++ Note: df101 -1549.12 -1549.12 -1549.12 C++ Note: df102 -1377.03 -753.296 -455.699 C++ Note: df103 -1491.03 -2204.79 -1131.21 C++ Note: df104 -0.628972 -0.13964 -0.250617 C++ Note: Checking Deviance 2870.24 C++ Note: df105 0.923543 0.341663 0.402843 C++ Note: df106 1.12497 2.05646 3.39944 C++ Note: Starting Halves C++ Note: df501 -1549.12 C++ Note: df504 -0.6289719 -0.1396396 -0.2506166 C++ Note: values checked -1.32163 -0.395887 -0.552749 C++ Note: sums checked 266.7 521.09 519.145 C++ Note: derivs checked 266.7 671.07 434.573 C++ Note: second derivs checked 266.7 1729.52 864.477 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 266.7 521.09 519.145 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 266.7 521.09 519.145 C++ Note: risk checked 544.132 C++ Note: risk1 checked 544.132 178.975 115.901 C++ Note: risk2 checked 544.132 461.263 230.557 C++ Note: df101 -777.948 -777.948 -777.948 C++ Note: df102 -502.126 -162.553 -97.929 C++ Note: df103 -616.126 -439.003 -204.214 C++ Note: df104 -1.32163 -0.395887 -0.552749 C++ Note: Checking Deviance 1327.9 C++ Note: df105 0.814973 0.370278 0.47954 C++ Note: df106 1.54931 4.78581 7.944 C++ Note: df100 4886 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 4934 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -777.9483 -777.9483 -777.9483 C++ Note: df102 -502.1257 -162.5533 -97.92904 C++ Note: df103 -616.1257 -439.0029 -204.2144 C++ Note: df104 -1.321629 -0.395887 -0.5527491 C++ Note: Checking Deviance 1327.897 C++ Note: df105 0.8149728 0.3702783 0.4795403 C++ Note: df106 1.54931 4.785806 7.944 C++ Note: df101 -777.948 -777.948 -777.948 C++ Note: df102 -502.126 -162.553 -97.929 C++ Note: df103 -616.126 -439.003 -204.214 C++ Note: df104 -1.32163 -0.395887 -0.552749 C++ Note: Checking Deviance 1327.9 C++ Note: df105 0.814973 0.370278 0.47954 C++ Note: df106 1.54931 4.78581 7.944 C++ Note: df501 -777.9483 C++ Note: df504 -1.321629 -0.395887 -0.5527491 Warning: model covariate order changed Error: guesses: 100 , iterations per guess: c(1, 1) Warning: rmin and rmax lists not equal size, defaulting to lin and loglin min/max values Warning: rmin and rmax lists not equal size, defaulting to lin and loglin min/max values C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 1 C++ Note: df99,20,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 2 C++ Note: values checked 0.01 C++ Note: sums checked 10679.25 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 10679.25 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 10679.25 C++ Note: df99,706,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 Note: 1 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 1 C++ Note: df99,19,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 2 C++ Note: values checked 0.8605863 C++ Note: sums checked 3.253402e+32 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 3.253402e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 3.253402e+32 C++ Note: df99,371,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: START_POIS_GUESS C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 1 C++ Note: df99,22,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 2 in guess 0 C++ Note: values checked 0.01 C++ Note: sums checked 10679.3 C++ Note: derivs checked 564819 C++ Note: second derivs checked 3.34438e+07 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 10679.3 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 10679.3 C++ Note: risk checked 121.53 C++ Note: risk1 checked 4019.07 C++ Note: risk2 checked 237975 C++ Note: df101 -455.955 C++ Note: df102 -880.754 C++ Note: df103 -164749 C++ Note: df104 0.01 C++ Note: Checking Deviance 739.91 C++ Note: df105 0.00534604 C++ Note: df106 0.517687 C++ Note: Starting Halves C++ Note: df501 -455.9548 C++ Note: df504 0.01 C++ Note: values checked 0.00599047 C++ Note: sums checked 8661.97 C++ Note: derivs checked 446431 C++ Note: second derivs checked 2.5943e+07 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 8661.97 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 8661.97 C++ Note: risk checked 107.176 C++ Note: risk1 checked 3176.66 C++ Note: risk2 checked 184602 C++ Note: df101 -453.592 C++ Note: df102 -334.069 C++ Note: df103 -110449 C++ Note: df104 0.00599047 C++ Note: Checking Deviance 735.184 C++ Note: df105 0.00302466 C++ Note: df106 1.35778 C++ Note: df100 4820 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 4868 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -453.5921 C++ Note: df102 -334.0694 C++ Note: df103 -110448.7 C++ Note: df104 0.005990473 C++ Note: Checking Deviance 735.1842 C++ Note: df105 0.003024657 C++ Note: df106 1.357778 C++ Note: Starting Halves C++ Note: df501 -453.5921 C++ Note: df504 0.005990473 C++ Note: values checked 0.00372198 C++ Note: sums checked 7712.93 C++ Note: derivs checked 391577 C++ Note: second derivs checked 2.25045e+07 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 7712.93 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7712.93 C++ Note: risk checked 100.423 C++ Note: risk1 checked 2786.34 C++ Note: risk2 checked 160135 C++ Note: df101 -453.097 C++ Note: df102 -112.117 C++ Note: df103 -85914.4 C++ Note: df104 0.00372198 C++ Note: Checking Deviance 734.193 C++ Note: df105 0.00130499 C++ Note: df106 4.04127 C++ Note: df100 7242 1 2 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 7290 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -453.0965 C++ Note: df102 -112.1175 C++ Note: df103 -85914.38 C++ Note: df104 0.00372198 C++ Note: Checking Deviance 734.193 C++ Note: df105 0.001304991 C++ Note: df106 4.041266 C++ Note: Starting Halves C++ Note: df501 -453.0965 C++ Note: df504 0.00372198 C++ Note: values checked 0.00274324 C++ Note: sums checked 7340.24 C++ Note: derivs checked 370210 C++ Note: second derivs checked 2.11728e+07 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 7340.24 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7340.24 C++ Note: risk checked 97.771 C++ Note: risk1 checked 2634.29 C++ Note: risk2 checked 150659 C++ Note: df101 -453.026 C++ Note: df102 -32.671 C++ Note: df103 -76546.2 C++ Note: df104 0.00274324 C++ Note: Checking Deviance 734.053 C++ Note: df105 0.000426814 C++ Note: df106 13.8663 C++ Note: df100 9611 1 3 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 9659 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -453.0264 C++ Note: df102 -32.67097 C++ Note: df103 -76546.19 C++ Note: df104 0.002743237 C++ Note: Checking Deviance 734.0528 C++ Note: df105 0.0004268137 C++ Note: df106 13.86633 C++ Note: Starting Halves C++ Note: df501 -453.0264 C++ Note: df504 0.002743237 C++ Note: values checked 0.00242313 C++ Note: sums checked 7222.81 C++ Note: derivs checked 363499 C++ Note: second derivs checked 2.07555e+07 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 7222.81 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7222.81 C++ Note: risk checked 96.9354 C++ Note: risk1 checked 2586.54 C++ Note: risk2 checked 147689 C++ Note: df101 -453.02 C++ Note: df102 -8.6361 C++ Note: df103 -73632 C++ Note: df104 0.00242313 C++ Note: Checking Deviance 734.04 C++ Note: df105 0.000117287 C++ Note: df106 52.4565 C++ Note: df100 11991 1 4 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 12038 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -453.0198 C++ Note: df102 -8.636103 C++ Note: df103 -73632.01 C++ Note: df104 0.002423127 C++ Note: Checking Deviance 734.0397 C++ Note: df105 0.0001172873 C++ Note: df106 52.45651 C++ Note: Starting Halves C++ Note: df501 -453.0198 C++ Note: df504 0.002423127 C++ Note: values checked 0.00233516 C++ Note: sums checked 7190.92 C++ Note: derivs checked 361679 C++ Note: second derivs checked 2.06424e+07 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 7190.92 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7190.92 C++ Note: risk checked 96.7085 C++ Note: risk1 checked 2573.58 C++ Note: risk2 checked 146884 C++ Note: df101 -453.019 C++ Note: df102 -2.19373 C++ Note: df103 -72843.8 C++ Note: df104 0.00233516 C++ Note: Checking Deviance 734.039 C++ Note: df105 3.01155e-05 C++ Note: df106 206.506 C++ Note: df100 14374 1 5 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 14422 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -453.0194 C++ Note: df102 -2.193732 C++ Note: df103 -72843.83 C++ Note: df104 0.002335161 C++ Note: Checking Deviance 734.0387 C++ Note: df105 3.011555e-05 C++ Note: df106 206.5063 C++ Note: df101 -453.019 C++ Note: df102 -2.19373 C++ Note: df103 -72843.8 C++ Note: df104 0.00233516 C++ Note: Checking Deviance 734.039 C++ Note: df105 3.01155e-05 C++ Note: df106 206.506 C++ Note: ending guess 0 C++ Note: df501 -453.0194 C++ Note: df504 0.002335161 C++ Note: starting subterms 2 in guess 1 C++ Note: values checked 0.860586 C++ Note: sums checked 3.2534e+32 C++ Note: derivs checked 2.61141e+34 C++ Note: second derivs checked 2.09652e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 3.2534e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 3.2534e+32 C++ Note: risk checked 2.31501e+30 C++ Note: risk1 checked 1.8582e+32 C++ Note: risk2 checked 1.49181e+34 C++ Note: df101 -2.18588e+30 C++ Note: df102 -1.75454e+32 C++ Note: df103 -1.4086e+34 C++ Note: df104 0.860586 C++ Note: Checking Deviance 4.37176e+30 C++ Note: df105 0.0124559 C++ Note: df106 0.0124584 C++ Note: Starting Halves C++ Note: df501 -453.0194 C++ Note: df504 0.002335161 C++ Note: values checked 0.851244 C++ Note: sums checked 1.53711e+32 C++ Note: derivs checked 1.23361e+34 C++ Note: second derivs checked 9.90236e+35 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 1.53711e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 1.53711e+32 C++ Note: risk checked 1.09376e+30 C++ Note: risk1 checked 8.77797e+31 C++ Note: risk2 checked 7.04619e+33 C++ Note: df101 -1.03275e+30 C++ Note: df102 -8.28832e+31 C++ Note: df103 -6.65315e+33 C++ Note: df104 0.851244 C++ Note: Checking Deviance 2.06549e+30 C++ Note: df105 0.0124577 C++ Note: df106 0.0124603 C++ Note: df100 19769 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.855915 C++ Note: sums checked 2.23622e+32 C++ Note: derivs checked 1.79482e+34 C++ Note: second derivs checked 1.44083e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 2.23622e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 2.23622e+32 C++ Note: risk checked 1.59122e+30 C++ Note: risk1 checked 1.27714e+32 C++ Note: risk2 checked 1.02525e+34 C++ Note: df101 -1.50246e+30 C++ Note: df102 -1.2059e+32 C++ Note: df103 -9.68059e+33 C++ Note: df104 0.855915 C++ Note: Checking Deviance 3.00493e+30 C++ Note: df105 0.0124568 C++ Note: df106 0.0124593 C++ Note: df100 21876 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.858251 C++ Note: sums checked 2.69727e+32 C++ Note: derivs checked 2.16495e+34 C++ Note: second derivs checked 1.73802e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 2.69727e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 2.69727e+32 C++ Note: risk checked 1.91929e+30 C++ Note: risk1 checked 1.5405e+32 C++ Note: risk2 checked 1.23672e+34 C++ Note: df101 -1.81223e+30 C++ Note: df102 -1.45457e+32 C++ Note: df103 -1.16773e+34 C++ Note: df104 0.858251 C++ Note: Checking Deviance 3.62446e+30 C++ Note: df105 0.0124564 C++ Note: df106 0.0124589 C++ Note: df100 24026 3 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.859419 C++ Note: sums checked 2.96231e+32 C++ Note: derivs checked 2.37772e+34 C++ Note: second derivs checked 1.90887e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 2.96231e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 2.96231e+32 C++ Note: risk checked 2.10788e+30 C++ Note: risk1 checked 1.69191e+32 C++ Note: risk2 checked 1.35829e+34 C++ Note: df101 -1.9903e+30 C++ Note: df102 -1.59753e+32 C++ Note: df103 -1.28252e+34 C++ Note: df104 0.859419 C++ Note: Checking Deviance 3.98061e+30 C++ Note: df105 0.0124562 C++ Note: df106 0.0124586 C++ Note: df100 26131 4 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.860002 C++ Note: sums checked 3.10445e+32 C++ Note: derivs checked 2.49183e+34 C++ Note: second derivs checked 2.0005e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 3.10445e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 3.10445e+32 C++ Note: risk checked 2.20902e+30 C++ Note: risk1 checked 1.7731e+32 C++ Note: risk2 checked 1.42349e+34 C++ Note: df101 -2.0858e+30 C++ Note: df102 -1.6742e+32 C++ Note: df103 -1.34408e+34 C++ Note: df104 0.860002 C++ Note: Checking Deviance 4.1716e+30 C++ Note: df105 0.0124561 C++ Note: df106 0.0124585 C++ Note: df100 28246 5 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Changing back to best C++ Note: values checked 0.860586 C++ Note: sums checked 3.2534e+32 C++ Note: derivs checked 2.61141e+34 C++ Note: second derivs checked 2.09652e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 3.2534e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 3.2534e+32 C++ Note: risk checked 2.31501e+30 C++ Note: risk1 checked 1.8582e+32 C++ Note: risk2 checked 1.49181e+34 C++ Note: df101 -2.18588e+30 C++ Note: df102 -1.75454e+32 C++ Note: df103 -1.4086e+34 C++ Note: df104 0.860586 C++ Note: Checking Deviance 4.37176e+30 C++ Note: df105 0.0124559 C++ Note: df106 0.0124584 C++ Note: df100 30395 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -2.18588e+30 C++ Note: df102 -1.754543e+32 C++ Note: df103 -1.4086e+34 C++ Note: df104 0.8605863 C++ Note: Checking Deviance 4.371759e+30 C++ Note: df105 0.01245594 C++ Note: df106 0.0124584 C++ Note: Starting Halves C++ Note: df501 -453.0194 C++ Note: df504 0.002335161 C++ Note: values checked 0.851244 C++ Note: sums checked 1.53711e+32 C++ Note: derivs checked 1.23361e+34 C++ Note: second derivs checked 9.90236e+35 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 1.53711e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 1.53711e+32 C++ Note: risk checked 1.09376e+30 C++ Note: risk1 checked 8.77797e+31 C++ Note: risk2 checked 7.04619e+33 C++ Note: df101 -1.03275e+30 C++ Note: df102 -8.28832e+31 C++ Note: df103 -6.65315e+33 C++ Note: df104 0.851244 C++ Note: Checking Deviance 2.06549e+30 C++ Note: df105 0.0124577 C++ Note: df106 0.0124603 C++ Note: df100 32690 1 2 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.855915 C++ Note: sums checked 2.23622e+32 C++ Note: derivs checked 1.79482e+34 C++ Note: second derivs checked 1.44083e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 2.23622e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 2.23622e+32 C++ Note: risk checked 1.59122e+30 C++ Note: risk1 checked 1.27714e+32 C++ Note: risk2 checked 1.02525e+34 C++ Note: df101 -1.50246e+30 C++ Note: df102 -1.2059e+32 C++ Note: df103 -9.68059e+33 C++ Note: df104 0.855915 C++ Note: Checking Deviance 3.00493e+30 C++ Note: df105 0.0124568 C++ Note: df106 0.0124593 C++ Note: df100 34847 2 2 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.858251 C++ Note: sums checked 2.69727e+32 C++ Note: derivs checked 2.16495e+34 C++ Note: second derivs checked 1.73802e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 2.69727e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 2.69727e+32 C++ Note: risk checked 1.91929e+30 C++ Note: risk1 checked 1.5405e+32 C++ Note: risk2 checked 1.23672e+34 C++ Note: df101 -1.81223e+30 C++ Note: df102 -1.45457e+32 C++ Note: df103 -1.16773e+34 C++ Note: df104 0.858251 C++ Note: Checking Deviance 3.62446e+30 C++ Note: df105 0.0124564 C++ Note: df106 0.0124589 C++ Note: df100 36957 3 2 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.859419 C++ Note: sums checked 2.96231e+32 C++ Note: derivs checked 2.37772e+34 C++ Note: second derivs checked 1.90887e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 2.96231e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 2.96231e+32 C++ Note: risk checked 2.10788e+30 C++ Note: risk1 checked 1.69191e+32 C++ Note: risk2 checked 1.35829e+34 C++ Note: df101 -1.9903e+30 C++ Note: df102 -1.59753e+32 C++ Note: df103 -1.28252e+34 C++ Note: df104 0.859419 C++ Note: Checking Deviance 3.98061e+30 C++ Note: df105 0.0124562 C++ Note: df106 0.0124586 C++ Note: df100 39102 4 2 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.860002 C++ Note: sums checked 3.10445e+32 C++ Note: derivs checked 2.49183e+34 C++ Note: second derivs checked 2.0005e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 3.10445e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 3.10445e+32 C++ Note: risk checked 2.20902e+30 C++ Note: risk1 checked 1.7731e+32 C++ Note: risk2 checked 1.42349e+34 C++ Note: df101 -2.0858e+30 C++ Note: df102 -1.6742e+32 C++ Note: df103 -1.34408e+34 C++ Note: df104 0.860002 C++ Note: Checking Deviance 4.1716e+30 C++ Note: df105 0.0124561 C++ Note: df106 0.0124585 C++ Note: df100 41245 5 2 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Changing back to best C++ Note: values checked 0.860586 C++ Note: sums checked 3.2534e+32 C++ Note: derivs checked 2.61141e+34 C++ Note: second derivs checked 2.09652e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 3.2534e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 3.2534e+32 C++ Note: risk checked 2.31501e+30 C++ Note: risk1 checked 1.8582e+32 C++ Note: risk2 checked 1.49181e+34 C++ Note: df101 -2.18588e+30 C++ Note: df102 -1.75454e+32 C++ Note: df103 -1.4086e+34 C++ Note: df104 0.860586 C++ Note: Checking Deviance 4.37176e+30 C++ Note: df105 0.0124559 C++ Note: df106 0.0124584 C++ Note: df100 43406 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -2.18588e+30 C++ Note: df102 -1.754543e+32 C++ Note: df103 -1.4086e+34 C++ Note: df104 0.8605863 C++ Note: Checking Deviance 4.371759e+30 C++ Note: df105 0.01245594 C++ Note: df106 0.0124584 C++ Note: Starting Halves C++ Note: df501 -453.0194 C++ Note: df504 0.002335161 C++ Note: values checked 0.85961 C++ Note: sums checked 3.00812e+32 C++ Note: derivs checked 2.4145e+34 C++ Note: second derivs checked 1.9384e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 3.00812e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 3.00812e+32 C++ Note: risk checked 2.14048e+30 C++ Note: risk1 checked 1.71808e+32 C++ Note: risk2 checked 1.3793e+34 C++ Note: df101 -2.02108e+30 C++ Note: df102 -1.62224e+32 C++ Note: df103 -1.30236e+34 C++ Note: df104 0.85961 C++ Note: Checking Deviance 4.04216e+30 C++ Note: df105 0.0124561 C++ Note: df106 0.0124586 C++ Note: df100 45679 1 3 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.860098 C++ Note: sums checked 3.12836e+32 C++ Note: derivs checked 2.51103e+34 C++ Note: second derivs checked 2.01591e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 3.12836e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 3.12836e+32 C++ Note: risk checked 2.22604e+30 C++ Note: risk1 checked 1.78676e+32 C++ Note: risk2 checked 1.43446e+34 C++ Note: df101 -2.10187e+30 C++ Note: df102 -1.6871e+32 C++ Note: df103 -1.35444e+34 C++ Note: df104 0.860098 C++ Note: Checking Deviance 4.20373e+30 C++ Note: df105 0.012456 C++ Note: df106 0.0124585 C++ Note: df100 47782 2 3 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.860342 C++ Note: sums checked 3.19027e+32 C++ Note: derivs checked 2.56073e+34 C++ Note: second derivs checked 2.05582e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 3.19027e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 3.19027e+32 C++ Note: risk checked 2.27009e+30 C++ Note: risk1 checked 1.82213e+32 C++ Note: risk2 checked 1.46285e+34 C++ Note: df101 -2.14346e+30 C++ Note: df102 -1.72049e+32 C++ Note: df103 -1.38125e+34 C++ Note: df104 0.860342 C++ Note: Checking Deviance 4.28692e+30 C++ Note: df105 0.012456 C++ Note: df106 0.0124584 C++ Note: df100 49883 3 3 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.860464 C++ Note: sums checked 3.22168e+32 C++ Note: derivs checked 2.58595e+34 C++ Note: second derivs checked 2.07607e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 3.22168e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 3.22168e+32 C++ Note: risk checked 2.29244e+30 C++ Note: risk1 checked 1.84007e+32 C++ Note: risk2 checked 1.47726e+34 C++ Note: df101 -2.16457e+30 C++ Note: df102 -1.73743e+32 C++ Note: df103 -1.39486e+34 C++ Note: df104 0.860464 C++ Note: Checking Deviance 4.32913e+30 C++ Note: df105 0.012456 C++ Note: df106 0.0124584 C++ Note: df100 51985 4 3 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.860525 C++ Note: sums checked 3.2375e+32 C++ Note: derivs checked 2.59865e+34 C++ Note: second derivs checked 2.08627e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 3.2375e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 3.2375e+32 C++ Note: risk checked 2.3037e+30 C++ Note: risk1 checked 1.84911e+32 C++ Note: risk2 checked 1.48452e+34 C++ Note: df101 -2.1752e+30 C++ Note: df102 -1.74597e+32 C++ Note: df103 -1.40171e+34 C++ Note: df104 0.860525 C++ Note: Checking Deviance 4.35039e+30 C++ Note: df105 0.012456 C++ Note: df106 0.0124584 C++ Note: df100 54129 5 3 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Changing back to best C++ Note: values checked 0.860586 C++ Note: sums checked 3.2534e+32 C++ Note: derivs checked 2.61141e+34 C++ Note: second derivs checked 2.09652e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 3.2534e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 3.2534e+32 C++ Note: risk checked 2.31501e+30 C++ Note: risk1 checked 1.8582e+32 C++ Note: risk2 checked 1.49181e+34 C++ Note: df101 -2.18588e+30 C++ Note: df102 -1.75454e+32 C++ Note: df103 -1.4086e+34 C++ Note: df104 0.860586 C++ Note: Checking Deviance 4.37176e+30 C++ Note: df105 0.0124559 C++ Note: df106 0.0124584 C++ Note: df100 56239 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -2.18588e+30 C++ Note: df102 -1.754543e+32 C++ Note: df103 -1.4086e+34 C++ Note: df104 0.8605863 C++ Note: Checking Deviance 4.371759e+30 C++ Note: df105 0.01245594 C++ Note: df106 0.0124584 C++ Note: Starting Halves C++ Note: df501 -453.0194 C++ Note: df504 0.002335161 C++ Note: values checked 0.860556 C++ Note: sums checked 3.24544e+32 C++ Note: derivs checked 2.60502e+34 C++ Note: second derivs checked 2.09139e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 3.24544e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 3.24544e+32 C++ Note: risk checked 2.30935e+30 C++ Note: risk1 checked 1.85365e+32 C++ Note: risk2 checked 1.48816e+34 C++ Note: df101 -2.18053e+30 C++ Note: df102 -1.75025e+32 C++ Note: df103 -1.40515e+34 C++ Note: df104 0.860556 C++ Note: Checking Deviance 4.36106e+30 C++ Note: df105 0.0124559 C++ Note: df106 0.0124584 C++ Note: df100 58493 1 4 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.860571 C++ Note: sums checked 3.24942e+32 C++ Note: derivs checked 2.60822e+34 C++ Note: second derivs checked 2.09395e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 3.24942e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 3.24942e+32 C++ Note: risk checked 2.31218e+30 C++ Note: risk1 checked 1.85592e+32 C++ Note: risk2 checked 1.48999e+34 C++ Note: df101 -2.1832e+30 C++ Note: df102 -1.7524e+32 C++ Note: df103 -1.40687e+34 C++ Note: df104 0.860571 C++ Note: Checking Deviance 4.36641e+30 C++ Note: df105 0.0124559 C++ Note: df106 0.0124584 C++ Note: df100 60619 2 4 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.860579 C++ Note: sums checked 3.25141e+32 C++ Note: derivs checked 2.60981e+34 C++ Note: second derivs checked 2.09524e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 3.25141e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 3.25141e+32 C++ Note: risk checked 2.3136e+30 C++ Note: risk1 checked 1.85706e+32 C++ Note: risk2 checked 1.4909e+34 C++ Note: df101 -2.18454e+30 C++ Note: df102 -1.75347e+32 C++ Note: df103 -1.40774e+34 C++ Note: df104 0.860579 C++ Note: Checking Deviance 4.36908e+30 C++ Note: df105 0.0124559 C++ Note: df106 0.0124584 C++ Note: df100 62767 3 4 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.860582 C++ Note: sums checked 3.25241e+32 C++ Note: derivs checked 2.61061e+34 C++ Note: second derivs checked 2.09588e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 3.25241e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 3.25241e+32 C++ Note: risk checked 2.3143e+30 C++ Note: risk1 checked 1.85763e+32 C++ Note: risk2 checked 1.49136e+34 C++ Note: df101 -2.18521e+30 C++ Note: df102 -1.75401e+32 C++ Note: df103 -1.40817e+34 C++ Note: df104 0.860582 C++ Note: Checking Deviance 4.37042e+30 C++ Note: df105 0.0124559 C++ Note: df106 0.0124584 C++ Note: df100 64876 4 4 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.860584 C++ Note: sums checked 3.2529e+32 C++ Note: derivs checked 2.61101e+34 C++ Note: second derivs checked 2.0962e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 3.2529e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 3.2529e+32 C++ Note: risk checked 2.31466e+30 C++ Note: risk1 checked 1.85791e+32 C++ Note: risk2 checked 1.49159e+34 C++ Note: df101 -2.18555e+30 C++ Note: df102 -1.75427e+32 C++ Note: df103 -1.40838e+34 C++ Note: df104 0.860584 C++ Note: Checking Deviance 4.37109e+30 C++ Note: df105 0.0124559 C++ Note: df106 0.0124584 C++ Note: df100 67023 5 4 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Changing back to best C++ Note: values checked 0.860586 C++ Note: sums checked 3.2534e+32 C++ Note: derivs checked 2.61141e+34 C++ Note: second derivs checked 2.09652e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 3.2534e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 3.2534e+32 C++ Note: risk checked 2.31501e+30 C++ Note: risk1 checked 1.8582e+32 C++ Note: risk2 checked 1.49181e+34 C++ Note: df101 -2.18588e+30 C++ Note: df102 -1.75454e+32 C++ Note: df103 -1.4086e+34 C++ Note: df104 0.860586 C++ Note: Checking Deviance 4.37176e+30 C++ Note: df105 0.0124559 C++ Note: df106 0.0124584 C++ Note: df100 69169 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -2.18588e+30 C++ Note: df102 -1.754543e+32 C++ Note: df103 -1.4086e+34 C++ Note: df104 0.8605863 C++ Note: Checking Deviance 4.371759e+30 C++ Note: df105 0.01245594 C++ Note: df106 0.0124584 C++ Note: Starting Halves C++ Note: df501 -453.0194 C++ Note: df504 0.002335161 C++ Note: values checked 0.860585 C++ Note: sums checked 3.25315e+32 C++ Note: derivs checked 2.61121e+34 C++ Note: second derivs checked 2.09636e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 3.25315e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 3.25315e+32 C++ Note: risk checked 2.31484e+30 C++ Note: risk1 checked 1.85805e+32 C++ Note: risk2 checked 1.4917e+34 C++ Note: df101 -2.18571e+30 C++ Note: df102 -1.75441e+32 C++ Note: df103 -1.40849e+34 C++ Note: df104 0.860585 C++ Note: Checking Deviance 4.37142e+30 C++ Note: df105 0.0124559 C++ Note: df106 0.0124584 C++ Note: df100 71466 1 5 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.860586 C++ Note: sums checked 3.25328e+32 C++ Note: derivs checked 2.61131e+34 C++ Note: second derivs checked 2.09644e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 3.25328e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 3.25328e+32 C++ Note: risk checked 2.31493e+30 C++ Note: risk1 checked 1.85812e+32 C++ Note: risk2 checked 1.49176e+34 C++ Note: df101 -2.1858e+30 C++ Note: df102 -1.75448e+32 C++ Note: df103 -1.40855e+34 C++ Note: df104 0.860586 C++ Note: Checking Deviance 4.37159e+30 C++ Note: df105 0.0124559 C++ Note: df106 0.0124584 C++ Note: df100 73610 2 5 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.860586 C++ Note: sums checked 3.25334e+32 C++ Note: derivs checked 2.61136e+34 C++ Note: second derivs checked 2.09648e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 3.25334e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 3.25334e+32 C++ Note: risk checked 2.31497e+30 C++ Note: risk1 checked 1.85816e+32 C++ Note: risk2 checked 1.49179e+34 C++ Note: df101 -2.18584e+30 C++ Note: df102 -1.75451e+32 C++ Note: df103 -1.40857e+34 C++ Note: df104 0.860586 C++ Note: Checking Deviance 4.37168e+30 C++ Note: df105 0.0124559 C++ Note: df106 0.0124584 C++ Note: df100 75762 3 5 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.860586 C++ Note: sums checked 3.25337e+32 C++ Note: derivs checked 2.61139e+34 C++ Note: second derivs checked 2.0965e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 3.25337e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 3.25337e+32 C++ Note: risk checked 2.31499e+30 C++ Note: risk1 checked 1.85818e+32 C++ Note: risk2 checked 1.4918e+34 C++ Note: df101 -2.18586e+30 C++ Note: df102 -1.75453e+32 C++ Note: df103 -1.40859e+34 C++ Note: df104 0.860586 C++ Note: Checking Deviance 4.37172e+30 C++ Note: df105 0.0124559 C++ Note: df106 0.0124584 C++ Note: df100 77910 4 5 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.860586 C++ Note: sums checked 3.25339e+32 C++ Note: derivs checked 2.6114e+34 C++ Note: second derivs checked 2.09651e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 3.25339e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 3.25339e+32 C++ Note: risk checked 2.315e+30 C++ Note: risk1 checked 1.85819e+32 C++ Note: risk2 checked 1.49181e+34 C++ Note: df101 -2.18587e+30 C++ Note: df102 -1.75454e+32 C++ Note: df103 -1.40859e+34 C++ Note: df104 0.860586 C++ Note: Checking Deviance 4.37174e+30 C++ Note: df105 0.0124559 C++ Note: df106 0.0124584 C++ Note: df100 80051 5 5 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Changing back to best C++ Note: values checked 0.860586 C++ Note: sums checked 3.2534e+32 C++ Note: derivs checked 2.61141e+34 C++ Note: second derivs checked 2.09652e+36 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 3.2534e+32 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 3.2534e+32 C++ Note: risk checked 2.31501e+30 C++ Note: risk1 checked 1.8582e+32 C++ Note: risk2 checked 1.49181e+34 C++ Note: df101 -2.18588e+30 C++ Note: df102 -1.75454e+32 C++ Note: df103 -1.4086e+34 C++ Note: df104 0.860586 C++ Note: Checking Deviance 4.37176e+30 C++ Note: df105 0.0124559 C++ Note: df106 0.0124584 C++ Note: df100 82196 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -2.18588e+30 C++ Note: df102 -1.754543e+32 C++ Note: df103 -1.4086e+34 C++ Note: df104 0.8605863 C++ Note: Checking Deviance 4.371759e+30 C++ Note: df105 0.01245594 C++ Note: df106 0.0124584 C++ Note: df101 -2.18588e+30 C++ Note: df102 -1.75454e+32 C++ Note: df103 -1.4086e+34 C++ Note: df104 0.860586 C++ Note: Checking Deviance 4.37176e+30 C++ Note: df105 0.0124559 C++ Note: df106 0.0124584 C++ Note: ending guess 1 C++ Note: df501 -453.0194 C++ Note: df504 0.002335161 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.002335161, -453.0194<-- Best Guess 1, 0.8605863, -2.18588e+30 C++ Note: starting subterms 2 in best guess 0 C++ Note: values checked 0.00233516 C++ Note: sums checked 7190.92 C++ Note: derivs checked 361679 C++ Note: second derivs checked 2.06424e+07 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 7190.92 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7190.92 C++ Note: risk checked 96.7085 C++ Note: risk1 checked 2573.58 C++ Note: risk2 checked 146884 C++ Note: Made Risk Side Lists C++ Note: df101 -453.019 C++ Note: df102 -2.19373 C++ Note: df103 -72843.8 C++ Note: df104 0.00233516 C++ Note: Checking Deviance 734.039 C++ Note: df105 3.01155e-05 C++ Note: df106 206.506 C++ Note: Starting Halves C++ Note: df501 -453.0194 C++ Note: df504 0.002335161 C++ Note: values checked 0.00231257 C++ Note: sums checked 7182.75 C++ Note: derivs checked 361213 C++ Note: second derivs checked 2.06134e+07 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6400 7182.75 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7182.75 C++ Note: risk checked 96.6504 C++ Note: risk1 checked 2570.27 C++ Note: risk2 checked 146678 C++ Note: df101 -453.019 C++ Note: df102 -0.550709 C++ Note: df103 -72642.3 C++ Note: df104 0.00231257 C++ Note: Checking Deviance 734.039 C++ Note: df105 7.58111e-06 C++ Note: df106 822.611 C++ Note: df100 87652 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 87700 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -453.0193 C++ Note: df102 -0.5507093 C++ Note: df103 -72642.32 C++ Note: df104 0.002312575 C++ Note: Checking Deviance 734.0386 C++ Note: df105 7.581108e-06 C++ Note: df106 822.6106 C++ Note: df101 -453.019 C++ Note: df102 -0.550709 C++ Note: df103 -72642.3 C++ Note: df104 0.00231257 C++ Note: Checking Deviance 734.039 C++ Note: df105 7.58111e-06 C++ Note: df106 822.611 C++ Note: df501 -453.0193 C++ Note: df504 0.002312575 Note: INITIAL TERM COMPLETE -453.019321355954-0.550709301883533-72642.32341779490.002312574716865620.00371026677080554736.038642711906914.802695981256734.038642711906list(Term_n = 1, tforms = "loglin", names = "t0")list(Iteration = 1, `Maximum Step` = 1, `Derivative Limiting` = 0.550709301883533)FALSE Warning: rmin and rmax lists not equal size, defaulting to lin and loglin min/max values C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 1 2 C++ Note: df99,24,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 3 C++ Note: values checked 0.002312575 -15 C++ Note: sums checked 7182.753 2624.001 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7182.753 2624.001 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7182.753 2624.001 C++ Note: df99,954,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 Note: 1 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 1 2 C++ Note: df99,24,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 3 C++ Note: values checked 0.002312575 -14.33129 C++ Note: sums checked 7182.753 2624.002 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7182.753 2624.002 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7182.753 2624.002 C++ Note: df99,503,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: START_POIS_GUESS C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 1 2 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 3 in guess 0 C++ Note: values checked 0.00231257 -15 C++ Note: sums checked 7182.75 2624 C++ Note: derivs checked 361213 0.00115509 C++ Note: second derivs checked 2.06134e+07 0.00115509 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7182.75 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7182.75 2624 C++ Note: risk checked 69.0234 C++ Note: risk1 checked 1835.57 8.45116e-06 C++ Note: risk2 checked 104751 8.45116e-06 C++ Note: df101 -449.751 -449.751 C++ Note: df102 694.655 2.09788e-06 C++ Note: df103 -32968.8 2.09788e-06 C++ Note: df104 0.00231257 -15 C++ Note: Checking Deviance 727.502 C++ Note: df105 -0.02107 1 C++ Note: df106 -0.647445 -2.14383e+08 C++ Note: Starting Halves C++ Note: df501 -449.7512 C++ Note: df504 0.002312575 -15 C++ Note: values checked 0.0181151 -14.1481 C++ Note: sums checked 16582.9 2624 C++ Note: derivs checked 921141 0.0027077 C++ Note: second derivs checked 5.6465e+07 0.0027077 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 16582.9 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 16582.9 2624 C++ Note: risk checked 116.792 C++ Note: risk1 checked 4680.95 3.35213e-05 C++ Note: risk2 checked 286938 3.35213e-05 C++ Note: df101 -448.753 -448.753 C++ Note: df102 -1059.27 -8.05569e-06 C++ Note: df103 -222055 -8.05571e-06 C++ Note: df104 0.0181151 -14.1481 C++ Note: Checking Deviance 725.506 C++ Note: df105 0.00477029 0.999998 C++ Note: df106 0.423645 5.57063e+07 C++ Note: df100 6818 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 6867 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -448.753 -448.753 C++ Note: df102 -1059.267 -8.055693e-06 C++ Note: df103 -222055 -8.05571e-06 C++ Note: df104 0.0181151 -14.14807 C++ Note: Checking Deviance 725.506 C++ Note: df105 0.004770292 0.9999979 C++ Note: df106 0.4236448 5.570632e+07 C++ Note: Starting Halves C++ Note: df501 -448.753 C++ Note: df504 0.0181151 -14.14807 C++ Note: values checked 0.0145374 -14.3335 C++ Note: sums checked 13622.2 2624 C++ Note: derivs checked 740922 0.00224951 C++ Note: second derivs checked 4.47533e+07 0.00224951 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 13622.2 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 13622.2 2624 C++ Note: risk checked 101.747 C++ Note: risk1 checked 3765.14 2.42613e-05 C++ Note: risk2 checked 227423 2.42613e-05 C++ Note: df101 -446.246 -446.246 C++ Note: df102 -378.967 -3.2978e-06 C++ Note: df103 -160567 -3.29781e-06 C++ Note: df104 0.0145374 -14.3335 C++ Note: Checking Deviance 720.492 C++ Note: df105 0.00236018 0.999996 C++ Note: df106 1.17753 1.35316e+08 C++ Note: df100 10088 1 2 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 10136 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -446.2458 -446.2458 C++ Note: df102 -378.9665 -3.297802e-06 C++ Note: df103 -160566.9 -3.297813e-06 C++ Note: df104 0.01453739 -14.33346 C++ Note: Checking Deviance 720.4915 C++ Note: df105 0.002360179 0.9999964 C++ Note: df106 1.177533 1.353161e+08 C++ Note: Starting Halves C++ Note: df501 -446.2458 C++ Note: df504 0.01453739 -14.33346 C++ Note: values checked 0.0127673 -14.6275 C++ Note: sums checked 12378.2 2624 C++ Note: derivs checked 666059 0.0016765 C++ Note: second derivs checked 3.99267e+07 0.0016765 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 12378.2 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 12378.2 2624 C++ Note: risk checked 95.425 C++ Note: risk1 checked 3384.71 1.69579e-05 C++ Note: risk2 checked 202895 1.69579e-05 C++ Note: df101 -445.813 -445.813 C++ Note: df102 -117.841 -1.39473e-06 C++ Note: df103 -134954 -1.39474e-06 C++ Note: df104 0.0127673 -14.6275 C++ Note: Checking Deviance 719.625 C++ Note: df105 0.000873194 0.999995 C++ Note: df106 3.78318 3.19641e+08 C++ Note: df100 13367 1 3 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 13415 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -445.8127 -445.8127 C++ Note: df102 -117.8408 -1.39473e-06 C++ Note: df103 -134953.8 -1.394736e-06 C++ Note: df104 0.01276725 -14.62747 C++ Note: Checking Deviance 719.6255 C++ Note: df105 0.0008731937 0.9999953 C++ Note: df106 3.783177 3.19641e+08 C++ Note: Starting Halves C++ Note: df501 -445.8127 C++ Note: df504 0.01276725 -14.62747 C++ Note: values checked 0.0121124 -15.1102 C++ Note: sums checked 11950.4 2624 C++ Note: derivs checked 640454 0.00103454 C++ Note: second derivs checked 3.82819e+07 0.00103454 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 11950.4 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 11950.4 2624 C++ Note: risk checked 93.2513 C++ Note: risk1 checked 3254.59 1.02261e-05 C++ Note: risk2 checked 194537 1.02261e-05 C++ Note: df101 -445.764 -445.764 C++ Note: df102 -32.3484 -6.35105e-07 C++ Note: df103 -126196 -6.35107e-07 C++ Note: df104 0.0121124 -15.1102 C++ Note: Checking Deviance 719.528 C++ Note: df105 0.000256336 0.999996 C++ Note: df106 13.7801 7.01874e+08 C++ Note: df100 16615 1 4 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 16663 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -445.7639 -445.7639 C++ Note: df102 -32.34844 -6.35105e-07 C++ Note: df103 -126195.7 -6.351075e-07 C++ Note: df104 0.01211236 -15.11022 C++ Note: Checking Deviance 719.5277 C++ Note: df105 0.0002563356 0.9999961 C++ Note: df106 13.78007 7.018743e+08 C++ Note: Starting Halves C++ Note: df501 -445.7639 C++ Note: df504 0.01211236 -15.11022 C++ Note: values checked 0.0119201 -15.758 C++ Note: sums checked 11828 2624 C++ Note: derivs checked 633140 0.000541285 C++ Note: second derivs checked 3.78127e+07 0.000541285 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 11828 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 11828 2624 C++ Note: risk checked 92.6292 C++ Note: risk1 checked 3217.42 5.3147e-06 C++ Note: risk2 checked 192153 5.3147e-06 C++ Note: df101 -445.76 -445.76 C++ Note: df102 -8.32807 -2.98518e-07 C++ Note: df103 -123695 -2.98519e-07 C++ Note: df104 0.0119201 -15.758 C++ Note: Checking Deviance 719.52 C++ Note: df105 6.73276e-05 0.999998 C++ Note: df106 53.525 1.49324e+09 C++ Note: df100 19887 1 5 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 19935 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -445.76 -445.76 C++ Note: df102 -8.328071 -2.985182e-07 C++ Note: df103 -123694.8 -2.985189e-07 C++ Note: df104 0.01192011 -15.75799 C++ Note: Checking Deviance 719.5199 C++ Note: df105 6.732758e-05 0.9999977 C++ Note: df106 53.525 1.493242e+09 C++ Note: df101 -445.76 -445.76 C++ Note: df102 -8.32807 -2.98518e-07 C++ Note: df103 -123695 -2.98519e-07 C++ Note: df104 0.0119201 -15.758 C++ Note: Checking Deviance 719.52 C++ Note: df105 6.73276e-05 0.999998 C++ Note: df106 53.525 1.49324e+09 C++ Note: ending guess 0 C++ Note: df501 -445.76 C++ Note: df504 0.01192011 -15.75799 C++ Note: starting subterms 3 in guess 1 C++ Note: values checked 0.00231257 -14.3313 C++ Note: sums checked 7182.75 2624 C++ Note: derivs checked 361213 0.0022544 C++ Note: second derivs checked 2.06134e+07 0.0022544 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7182.75 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7182.75 2624 C++ Note: risk checked 69.0234 C++ Note: risk1 checked 1835.57 1.64943e-05 C++ Note: risk2 checked 104751 1.64943e-05 C++ Note: df101 -449.751 -449.751 C++ Note: df102 694.655 4.09446e-06 C++ Note: df103 -32968.9 4.09445e-06 C++ Note: df104 0.00231257 -14.3313 C++ Note: Checking Deviance 727.502 C++ Note: df105 -0.02107 1 C++ Note: df106 -0.647446 -1.09844e+08 C++ Note: Starting Halves C++ Note: df501 -445.76 C++ Note: df504 0.01192011 -15.75799 C++ Note: values checked 0.0181151 -13.4794 C++ Note: sums checked 16582.9 2624.01 C++ Note: derivs checked 921140 0.00528468 C++ Note: second derivs checked 5.64649e+07 0.00528468 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 16582.9 2624.01 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 16582.9 2624.01 C++ Note: risk checked 116.792 C++ Note: risk1 checked 4680.95 6.54241e-05 C++ Note: risk2 checked 286938 6.54241e-05 C++ Note: df101 -448.753 -448.753 C++ Note: df102 -1059.27 -1.57224e-05 C++ Note: df103 -222055 -1.57225e-05 C++ Note: df104 0.0181151 -13.4794 C++ Note: Checking Deviance 725.506 C++ Note: df105 0.00477029 0.999996 C++ Note: df106 0.423646 2.85422e+07 C++ Note: df100 27227 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.0102138 -13.9053 C++ Note: sums checked 10800.8 2624 C++ Note: derivs checked 572020 0.00345164 C++ Note: second derivs checked 3.3903e+07 0.00345164 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 10800.8 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 10800.8 2624 C++ Note: risk checked 87.4092 C++ Note: risk1 checked 2906.83 3.19807e-05 C++ Note: risk2 checked 172285 3.19807e-05 C++ Note: df101 -445.915 -445.915 C++ Note: df102 184.596 -9.63941e-08 C++ Note: df103 -102833 -9.64217e-08 C++ Note: df104 0.0102138 -13.9053 C++ Note: Checking Deviance 719.831 C++ Note: df105 -0.00179511 0.999714 C++ Note: df106 -2.41563 4.62596e+09 C++ Note: df100 30247 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.0062632 -14.1183 C++ Note: sums checked 8784.69 2624 C++ Note: derivs checked 453568 0.00278951 C++ Note: second derivs checked 2.63923e+07 0.00278951 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 8784.69 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 8784.69 2624 C++ Note: risk checked 77.164 C++ Note: risk1 checked 2304.89 2.28165e-05 C++ Note: risk2 checked 134118 2.28165e-05 C++ Note: df101 -447.336 -447.336 C++ Note: df102 508.325 2.78865e-06 C++ Note: df103 -62884.4 2.78863e-06 C++ Note: df104 0.0062632 -14.1183 C++ Note: Checking Deviance 722.672 C++ Note: df105 -0.00808349 1.00001 C++ Note: df106 -0.880019 -1.60413e+08 C++ Note: df100 33286 3 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.00428789 -14.2248 C++ Note: sums checked 7938.18 2624 C++ Note: derivs checked 404541 0.00250772 C++ Note: second derivs checked 2.33147e+07 0.00250772 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7938.18 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7938.18 2624 C++ Note: risk checked 72.8622 C++ Note: risk1 checked 2055.75 1.93681e-05 C++ Note: risk2 checked 118478 1.93681e-05 C++ Note: df101 -448.452 -448.452 C++ Note: df102 616.246 3.58897e-06 C++ Note: df103 -46783.7 3.58895e-06 C++ Note: df104 0.00428789 -14.2248 C++ Note: Checking Deviance 724.904 C++ Note: df105 -0.0131723 1 C++ Note: df106 -0.727716 -1.24953e+08 C++ Note: df100 36329 4 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.00330023 -14.278 C++ Note: sums checked 7549.77 2624 C++ Note: derivs checked 382210 0.00237769 C++ Note: second derivs checked 2.19201e+07 0.00237769 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7549.77 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7549.77 2624 C++ Note: risk checked 70.8885 C++ Note: risk1 checked 1942.27 1.78664e-05 C++ Note: risk2 checked 111391 1.78664e-05 C++ Note: df101 -449.082 -449.082 C++ Note: df102 658.861 3.87359e-06 C++ Note: df103 -39603.2 3.87357e-06 C++ Note: df104 0.00330023 -14.278 C++ Note: Checking Deviance 726.165 C++ Note: df105 -0.0166366 1 C++ Note: df106 -0.681604 -1.15934e+08 C++ Note: df100 39382 5 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Changing back to best C++ Note: values checked 0.00231257 -14.3313 C++ Note: sums checked 7182.75 2624 C++ Note: derivs checked 361213 0.0022544 C++ Note: second derivs checked 2.06134e+07 0.0022544 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7182.75 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7182.75 2624 C++ Note: risk checked 69.0234 C++ Note: risk1 checked 1835.57 1.64943e-05 C++ Note: risk2 checked 104751 1.64943e-05 C++ Note: df101 -449.751 -449.751 C++ Note: df102 694.655 4.09446e-06 C++ Note: df103 -32968.9 4.09445e-06 C++ Note: df104 0.00231257 -14.3313 C++ Note: Checking Deviance 727.502 C++ Note: df105 -0.02107 1 C++ Note: df106 -0.647446 -1.09844e+08 C++ Note: df100 42605 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -449.7512 -449.7512 C++ Note: df102 694.6549 4.094464e-06 C++ Note: df103 -32968.86 4.094452e-06 C++ Note: df104 0.002312575 -14.33129 C++ Note: Checking Deviance 727.5024 C++ Note: df105 -0.02107003 1.000003 C++ Note: df106 -0.6474455 -1.098437e+08 C++ Note: Starting Halves C++ Note: df501 -445.76 C++ Note: df504 0.01192011 -15.75799 C++ Note: values checked 0.0181151 -14.3 C++ Note: sums checked 16582.9 2624 C++ Note: derivs checked 921140 0.00232596 C++ Note: second derivs checked 5.64649e+07 0.00232596 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 16582.9 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 16582.9 2624 C++ Note: risk checked 116.792 C++ Note: risk1 checked 4680.95 2.87953e-05 C++ Note: risk2 checked 286938 2.87953e-05 C++ Note: df101 -448.753 -448.753 C++ Note: df102 -1059.26 -6.91996e-06 C++ Note: df103 -222055 -6.91997e-06 C++ Note: df104 0.0181151 -14.3 C++ Note: Checking Deviance 725.506 C++ Note: df105 0.00477028 0.999998 C++ Note: df106 0.423646 6.48491e+07 C++ Note: df100 45839 1 2 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.0102138 -14.3157 C++ Note: sums checked 10800.8 2624 C++ Note: derivs checked 572020 0.0022899 C++ Note: second derivs checked 3.3903e+07 0.0022899 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 10800.8 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 10800.8 2624 C++ Note: risk checked 87.4092 C++ Note: risk1 checked 2906.83 2.12168e-05 C++ Note: risk2 checked 172285 2.12168e-05 C++ Note: df101 -445.915 -445.915 C++ Note: df102 184.596 -6.39442e-08 C++ Note: df103 -102833 -6.39563e-08 C++ Note: df104 0.0102138 -14.3157 C++ Note: Checking Deviance 719.831 C++ Note: df105 -0.00179511 0.99981 C++ Note: df106 -2.41563 6.97351e+09 C++ Note: df100 48849 2 2 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.0062632 -14.3235 C++ Note: sums checked 8784.69 2624 C++ Note: derivs checked 453568 0.00227208 C++ Note: second derivs checked 2.63923e+07 0.00227208 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 8784.69 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 8784.69 2624 C++ Note: risk checked 77.164 C++ Note: risk1 checked 2304.89 1.85842e-05 C++ Note: risk2 checked 134118 1.85842e-05 C++ Note: df101 -447.336 -447.336 C++ Note: df102 508.325 2.27138e-06 C++ Note: df103 -62884.3 2.27137e-06 C++ Note: df104 0.0062632 -14.3235 C++ Note: Checking Deviance 722.672 C++ Note: df105 -0.00808349 1.00001 C++ Note: df106 -0.880019 -1.96944e+08 C++ Note: df100 51869 3 2 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.00428789 -14.3274 C++ Note: sums checked 7938.18 2624 C++ Note: derivs checked 404541 0.00226323 C++ Note: second derivs checked 2.33147e+07 0.00226323 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7938.18 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7938.18 2624 C++ Note: risk checked 72.8622 C++ Note: risk1 checked 2055.75 1.74798e-05 C++ Note: risk2 checked 118478 1.74798e-05 C++ Note: df101 -448.452 -448.452 C++ Note: df102 616.246 3.23905e-06 C++ Note: df103 -46783.7 3.23904e-06 C++ Note: df104 0.00428789 -14.3274 C++ Note: Checking Deviance 724.904 C++ Note: df105 -0.0131723 1 C++ Note: df106 -0.727715 -1.38452e+08 C++ Note: df100 54921 4 2 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.00330023 -14.3293 C++ Note: sums checked 7549.77 2624 C++ Note: derivs checked 382210 0.00225881 C++ Note: second derivs checked 2.19201e+07 0.00225881 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7549.77 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7549.77 2624 C++ Note: risk checked 70.8885 C++ Note: risk1 checked 1942.27 1.69731e-05 C++ Note: risk2 checked 111391 1.69731e-05 C++ Note: df101 -449.082 -449.082 C++ Note: df102 658.861 3.67991e-06 C++ Note: df103 -39603.2 3.6799e-06 C++ Note: df104 0.00330023 -14.3293 C++ Note: Checking Deviance 726.165 C++ Note: df105 -0.0166366 1 C++ Note: df106 -0.681604 -1.22036e+08 C++ Note: df100 57999 5 2 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Changing back to best C++ Note: values checked 0.00231257 -14.3313 C++ Note: sums checked 7182.75 2624 C++ Note: derivs checked 361213 0.0022544 C++ Note: second derivs checked 2.06134e+07 0.0022544 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7182.75 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7182.75 2624 C++ Note: risk checked 69.0234 C++ Note: risk1 checked 1835.57 1.64943e-05 C++ Note: risk2 checked 104751 1.64943e-05 C++ Note: df101 -449.751 -449.751 C++ Note: df102 694.655 4.09446e-06 C++ Note: df103 -32968.9 4.09445e-06 C++ Note: df104 0.00231257 -14.3313 C++ Note: Checking Deviance 727.502 C++ Note: df105 -0.02107 1 C++ Note: df106 -0.647446 -1.09844e+08 C++ Note: df100 61076 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -449.7512 -449.7512 C++ Note: df102 694.6549 4.094464e-06 C++ Note: df103 -32968.86 4.094452e-06 C++ Note: df104 0.002312575 -14.33129 C++ Note: Checking Deviance 727.5024 C++ Note: df105 -0.02107003 1.000003 C++ Note: df106 -0.6474455 -1.098437e+08 C++ Note: Starting Halves C++ Note: df501 -445.76 C++ Note: df504 0.01192011 -15.75799 C++ Note: values checked 0.00328914 -14.3303 C++ Note: sums checked 7545.53 2624 C++ Note: derivs checked 381967 0.0022566 C++ Note: second derivs checked 2.1905e+07 0.0022566 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7545.53 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7545.53 2624 C++ Note: risk checked 70.8669 C++ Note: risk1 checked 1941.04 1.69514e-05 C++ Note: risk2 checked 111314 1.69514e-05 C++ Note: df101 -449.09 -449.09 C++ Note: df102 659.3 3.6812e-06 C++ Note: df103 -39525.7 3.68118e-06 C++ Note: df104 0.00328914 -14.3303 C++ Note: Checking Deviance 726.179 C++ Note: df105 -0.0166803 1 C++ Note: df106 -0.681162 -1.21996e+08 C++ Note: df100 64334 1 3 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.00280086 -14.3308 C++ Note: sums checked 7361.61 2624 C++ Note: derivs checked 371432 0.0022555 C++ Note: second derivs checked 2.12488e+07 0.0022555 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7361.61 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7361.61 2624 C++ Note: risk checked 69.9323 C++ Note: risk1 checked 1887.5 1.67196e-05 C++ Note: risk2 checked 107980 1.67196e-05 C++ Note: df101 -449.416 -449.416 C++ Note: df102 677.778 3.89084e-06 C++ Note: df103 -36182 3.89083e-06 C++ Note: df104 0.00280086 -14.3308 C++ Note: Checking Deviance 726.832 C++ Note: df105 -0.0187324 1 C++ Note: df106 -0.663073 -1.15506e+08 C++ Note: df100 67402 2 3 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.00255672 -14.331 C++ Note: sums checked 7271.56 2624 C++ Note: derivs checked 366284 0.00225495 C++ Note: second derivs checked 2.09286e+07 0.00225495 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7271.56 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7271.56 2624 C++ Note: risk checked 69.4747 C++ Note: risk1 checked 1861.34 1.66062e-05 C++ Note: risk2 checked 106353 1.66062e-05 C++ Note: df101 -449.583 -449.583 C++ Note: df102 686.412 3.9934e-06 C++ Note: df103 -34559.3 3.99338e-06 C++ Note: df104 0.00255672 -14.331 C++ Note: Checking Deviance 727.165 C++ Note: df105 -0.0198619 1 C++ Note: df106 -0.654975 -1.12582e+08 C++ Note: df100 70468 3 3 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.00243465 -14.3312 C++ Note: sums checked 7227 2624 C++ Note: derivs checked 363738 0.00225468 C++ Note: second derivs checked 2.07704e+07 0.00225468 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7227 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7227 2624 C++ Note: risk checked 69.2483 C++ Note: risk1 checked 1848.41 1.655e-05 C++ Note: risk2 checked 105549 1.655e-05 C++ Note: df101 -449.667 -449.667 C++ Note: df102 690.582 4.04411e-06 C++ Note: df103 -33760.1 4.0441e-06 C++ Note: df104 0.00243465 -14.3312 C++ Note: Checking Deviance 727.333 C++ Note: df105 -0.0204556 1 C++ Note: df106 -0.651141 -1.1119e+08 C++ Note: df100 73540 4 3 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.00237361 -14.3312 C++ Note: sums checked 7204.84 2624 C++ Note: derivs checked 362473 0.00225454 C++ Note: second derivs checked 2.06917e+07 0.00225454 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7204.84 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7204.84 2624 C++ Note: risk checked 69.1356 C++ Note: risk1 checked 1841.98 1.65221e-05 C++ Note: risk2 checked 105149 1.65221e-05 C++ Note: df101 -449.709 -449.709 C++ Note: df102 692.631 4.06933e-06 C++ Note: df103 -33363.5 4.06932e-06 C++ Note: df104 0.00237361 -14.3312 C++ Note: Checking Deviance 727.418 C++ Note: df105 -0.0207602 1 C++ Note: df106 -0.649277 -1.10512e+08 C++ Note: df100 76610 5 3 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Changing back to best C++ Note: values checked 0.00231257 -14.3313 C++ Note: sums checked 7182.75 2624 C++ Note: derivs checked 361213 0.0022544 C++ Note: second derivs checked 2.06134e+07 0.0022544 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7182.75 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7182.75 2624 C++ Note: risk checked 69.0234 C++ Note: risk1 checked 1835.57 1.64943e-05 C++ Note: risk2 checked 104751 1.64943e-05 C++ Note: df101 -449.751 -449.751 C++ Note: df102 694.655 4.09446e-06 C++ Note: df103 -32968.9 4.09445e-06 C++ Note: df104 0.00231257 -14.3313 C++ Note: Checking Deviance 727.502 C++ Note: df105 -0.02107 1 C++ Note: df106 -0.647446 -1.09844e+08 C++ Note: df100 79694 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -449.7512 -449.7512 C++ Note: df102 694.6549 4.094464e-06 C++ Note: df103 -32968.86 4.094452e-06 C++ Note: df104 0.002312575 -14.33129 C++ Note: Checking Deviance 727.5024 C++ Note: df105 -0.02107003 1.000003 C++ Note: df106 -0.6474455 -1.098437e+08 C++ Note: Starting Halves C++ Note: df501 -445.76 C++ Note: df504 0.01192011 -15.75799 C++ Note: values checked 0.00234309 -14.3313 C++ Note: sums checked 7193.79 2624 C++ Note: derivs checked 361842 0.00225447 C++ Note: second derivs checked 2.06525e+07 0.00225447 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7193.79 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7193.79 2624 C++ Note: risk checked 69.0795 C++ Note: risk1 checked 1838.77 1.65082e-05 C++ Note: risk2 checked 104950 1.65082e-05 C++ Note: df101 -449.73 -449.73 C++ Note: df102 693.646 4.08191e-06 C++ Note: df103 -33165.9 4.0819e-06 C++ Note: df104 0.00234309 -14.3313 C++ Note: Checking Deviance 727.46 C++ Note: df105 -0.0209144 1 C++ Note: df106 -0.648357 -1.10176e+08 C++ Note: df100 82959 1 4 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.00232783 -14.3313 C++ Note: sums checked 7188.27 2624 C++ Note: derivs checked 361527 0.00225444 C++ Note: second derivs checked 2.0633e+07 0.00225444 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7188.27 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7188.27 2624 C++ Note: risk checked 69.0514 C++ Note: risk1 checked 1837.17 1.65012e-05 C++ Note: risk2 checked 104850 1.65012e-05 C++ Note: df101 -449.741 -449.741 C++ Note: df102 694.151 4.08819e-06 C++ Note: df103 -33067.3 4.08818e-06 C++ Note: df104 0.00232783 -14.3313 C++ Note: Checking Deviance 727.481 C++ Note: df105 -0.0209921 1 C++ Note: df106 -0.6479 -1.1001e+08 C++ Note: df100 85898 2 4 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.0023202 -14.3313 C++ Note: sums checked 7185.51 2624 C++ Note: derivs checked 361370 0.00225442 C++ Note: second derivs checked 2.06232e+07 0.00225442 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7185.51 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7185.51 2624 C++ Note: risk checked 69.0374 C++ Note: risk1 checked 1836.37 1.64977e-05 C++ Note: risk2 checked 104801 1.64977e-05 C++ Note: df101 -449.746 -449.746 C++ Note: df102 694.403 4.09133e-06 C++ Note: df103 -33018.1 4.09132e-06 C++ Note: df104 0.0023202 -14.3313 C++ Note: Checking Deviance 727.492 C++ Note: df105 -0.021031 1 C++ Note: df106 -0.647673 -1.09927e+08 C++ Note: df100 89073 3 4 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.00231639 -14.3313 C++ Note: sums checked 7184.13 2624 C++ Note: derivs checked 361291 0.00225441 C++ Note: second derivs checked 2.06183e+07 0.00225441 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7184.13 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7184.13 2624 C++ Note: risk checked 69.0304 C++ Note: risk1 checked 1835.97 1.6496e-05 C++ Note: risk2 checked 104776 1.6496e-05 C++ Note: df101 -449.749 -449.749 C++ Note: df102 694.529 4.0929e-06 C++ Note: df103 -32993.5 4.09288e-06 C++ Note: df104 0.00231639 -14.3313 C++ Note: Checking Deviance 727.497 C++ Note: df105 -0.0210505 1 C++ Note: df106 -0.647559 -1.09885e+08 C++ Note: df100 92162 4 4 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.00231448 -14.3313 C++ Note: sums checked 7183.44 2624 C++ Note: derivs checked 361252 0.00225441 C++ Note: second derivs checked 2.06159e+07 0.00225441 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7183.44 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7183.44 2624 C++ Note: risk checked 69.0269 C++ Note: risk1 checked 1835.77 1.64951e-05 C++ Note: risk2 checked 104763 1.64951e-05 C++ Note: df101 -449.75 -449.75 C++ Note: df102 694.592 4.09368e-06 C++ Note: df103 -32981.2 4.09367e-06 C++ Note: df104 0.00231448 -14.3313 C++ Note: Checking Deviance 727.5 C++ Note: df105 -0.0210603 1 C++ Note: df106 -0.647502 -1.09864e+08 C++ Note: df100 95231 5 4 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Changing back to best C++ Note: values checked 0.00231257 -14.3313 C++ Note: sums checked 7182.75 2624 C++ Note: derivs checked 361213 0.0022544 C++ Note: second derivs checked 2.06134e+07 0.0022544 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7182.75 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7182.75 2624 C++ Note: risk checked 69.0234 C++ Note: risk1 checked 1835.57 1.64943e-05 C++ Note: risk2 checked 104751 1.64943e-05 C++ Note: df101 -449.751 -449.751 C++ Note: df102 694.655 4.09446e-06 C++ Note: df103 -32968.9 4.09445e-06 C++ Note: df104 0.00231257 -14.3313 C++ Note: Checking Deviance 727.502 C++ Note: df105 -0.02107 1 C++ Note: df106 -0.647446 -1.09844e+08 C++ Note: df100 98315 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -449.7512 -449.7512 C++ Note: df102 694.6549 4.094464e-06 C++ Note: df103 -32968.86 4.094452e-06 C++ Note: df104 0.002312575 -14.33129 C++ Note: Checking Deviance 727.5024 C++ Note: df105 -0.02107003 1.000003 C++ Note: df106 -0.6474455 -1.098437e+08 C++ Note: Starting Halves C++ Note: df501 -445.76 C++ Note: df504 0.01192011 -15.75799 C++ Note: values checked 0.00231353 -14.3313 C++ Note: sums checked 7183.1 2624 C++ Note: derivs checked 361232 0.0022544 C++ Note: second derivs checked 2.06146e+07 0.0022544 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7183.1 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7183.1 2624 C++ Note: risk checked 69.0252 C++ Note: risk1 checked 1835.67 1.64947e-05 C++ Note: risk2 checked 104757 1.64947e-05 C++ Note: df101 -449.751 -449.751 C++ Note: df102 694.623 4.09407e-06 C++ Note: df103 -32975 4.09406e-06 C++ Note: df104 0.00231353 -14.3313 C++ Note: Checking Deviance 727.501 C++ Note: df105 -0.0210652 1 C++ Note: df106 -0.647474 -1.09854e+08 C++ Note: df100 101590 1 5 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.00231305 -14.3313 C++ Note: sums checked 7182.93 2624 C++ Note: derivs checked 361222 0.0022544 C++ Note: second derivs checked 2.0614e+07 0.0022544 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7182.93 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7182.93 2624 C++ Note: risk checked 69.0243 C++ Note: risk1 checked 1835.62 1.64945e-05 C++ Note: risk2 checked 104754 1.64945e-05 C++ Note: df101 -449.751 -449.751 C++ Note: df102 694.639 4.09427e-06 C++ Note: df103 -32971.9 4.09426e-06 C++ Note: df104 0.00231305 -14.3313 C++ Note: Checking Deviance 727.502 C++ Note: df105 -0.0210676 1 C++ Note: df106 -0.64746 -1.09849e+08 C++ Note: df100 104674 2 5 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.00231281 -14.3313 C++ Note: sums checked 7182.84 2624 C++ Note: derivs checked 361218 0.0022544 C++ Note: second derivs checked 2.06137e+07 0.0022544 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7182.84 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7182.84 2624 C++ Note: risk checked 69.0238 C++ Note: risk1 checked 1835.6 1.64944e-05 C++ Note: risk2 checked 104753 1.64944e-05 C++ Note: df101 -449.751 -449.751 C++ Note: df102 694.647 4.09437e-06 C++ Note: df103 -32970.4 4.09435e-06 C++ Note: df104 0.00231281 -14.3313 C++ Note: Checking Deviance 727.502 C++ Note: df105 -0.0210688 1 C++ Note: df106 -0.647453 -1.09846e+08 C++ Note: df100 107747 3 5 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.00231269 -14.3313 C++ Note: sums checked 7182.8 2624 C++ Note: derivs checked 361215 0.0022544 C++ Note: second derivs checked 2.06136e+07 0.0022544 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7182.8 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7182.8 2624 C++ Note: risk checked 69.0236 C++ Note: risk1 checked 1835.58 1.64943e-05 C++ Note: risk2 checked 104752 1.64943e-05 C++ Note: df101 -449.751 -449.751 C++ Note: df102 694.651 4.09442e-06 C++ Note: df103 -32969.6 4.0944e-06 C++ Note: df104 0.00231269 -14.3313 C++ Note: Checking Deviance 727.502 C++ Note: df105 -0.0210694 1 C++ Note: df106 -0.647449 -1.09845e+08 C++ Note: df100 110823 4 5 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked 0.00231263 -14.3313 C++ Note: sums checked 7182.77 2624 C++ Note: derivs checked 361214 0.0022544 C++ Note: second derivs checked 2.06135e+07 0.0022544 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7182.77 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7182.77 2624 C++ Note: risk checked 69.0235 C++ Note: risk1 checked 1835.58 1.64943e-05 C++ Note: risk2 checked 104751 1.64943e-05 C++ Note: df101 -449.751 -449.751 C++ Note: df102 694.653 4.09444e-06 C++ Note: df103 -32969.2 4.09443e-06 C++ Note: df104 0.00231263 -14.3313 C++ Note: Checking Deviance 727.502 C++ Note: df105 -0.0210697 1 C++ Note: df106 -0.647447 -1.09844e+08 C++ Note: df100 113765 5 5 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Changing back to best C++ Note: values checked 0.00231257 -14.3313 C++ Note: sums checked 7182.75 2624 C++ Note: derivs checked 361213 0.0022544 C++ Note: second derivs checked 2.06134e+07 0.0022544 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 7182.75 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 7182.75 2624 C++ Note: risk checked 69.0234 C++ Note: risk1 checked 1835.57 1.64943e-05 C++ Note: risk2 checked 104751 1.64943e-05 C++ Note: df101 -449.751 -449.751 C++ Note: df102 694.655 4.09446e-06 C++ Note: df103 -32968.9 4.09445e-06 C++ Note: df104 0.00231257 -14.3313 C++ Note: Checking Deviance 727.502 C++ Note: df105 -0.02107 1 C++ Note: df106 -0.647446 -1.09844e+08 C++ Note: df100 116845 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -449.7512 -449.7512 C++ Note: df102 694.6549 4.094464e-06 C++ Note: df103 -32968.86 4.094452e-06 C++ Note: df104 0.002312575 -14.33129 C++ Note: Checking Deviance 727.5024 C++ Note: df105 -0.02107003 1.000003 C++ Note: df106 -0.6474455 -1.098437e+08 C++ Note: df101 -449.751 -449.751 C++ Note: df102 694.655 4.09446e-06 C++ Note: df103 -32968.9 4.09445e-06 C++ Note: df104 0.00231257 -14.3313 C++ Note: Checking Deviance 727.502 C++ Note: df105 -0.02107 1 C++ Note: df106 -0.647446 -1.09844e+08 C++ Note: ending guess 1 C++ Note: df501 -445.76 C++ Note: df504 0.01192011 -15.75799 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.01192011 -15.75799, -445.76<-- Best Guess 1, 0.002312575 -14.33129, -449.7512 C++ Note: starting subterms 3 in best guess 0 C++ Note: values checked 0.0119201 -15.758 C++ Note: sums checked 11828 2624 C++ Note: derivs checked 633140 0.000541285 C++ Note: second derivs checked 3.78127e+07 0.000541285 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 11828 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 11828 2624 C++ Note: risk checked 92.6292 C++ Note: risk1 checked 3217.42 5.3147e-06 C++ Note: risk2 checked 192153 5.3147e-06 C++ Note: Made Risk Side Lists C++ Note: df101 -445.76 -445.76 C++ Note: df102 -8.32807 -2.98518e-07 C++ Note: df103 -123695 -2.98519e-07 C++ Note: df104 0.0119201 -15.758 C++ Note: Checking Deviance 719.52 C++ Note: df105 6.73276e-05 0.999998 C++ Note: df106 53.525 1.49324e+09 C++ Note: Starting Halves C++ Note: df501 -445.76 C++ Note: df504 0.01192011 -15.75799 C++ Note: values checked 0.0118696 -16.4784 C++ Note: sums checked 11796.1 2624 C++ Note: derivs checked 631233 0.000263353 C++ Note: second derivs checked 3.76904e+07 0.000263353 C++ Note: dose checked 6400 6400 6400 C++ Note: non-dose checked 6400 11796.1 2624 C++ Note: LIN_non-dose checked 6400 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 6400 C++ Note: LOGLIN_non-dose checked 6400 11796.1 2624 C++ Note: risk checked 92.467 C++ Note: risk1 checked 3207.73 2.58125e-06 C++ Note: risk2 checked 191531 2.58125e-06 C++ Note: df101 -445.76 -445.76 C++ Note: df102 -2.09852 -1.40954e-07 C++ Note: df103 -123043 -1.40954e-07 C++ Note: df104 0.0118696 -16.4784 C++ Note: Checking Deviance 719.519 C++ Note: df105 1.70551e-05 0.999999 C++ Note: df106 212.417 3.16245e+09 C++ Note: df100 124094 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 124143 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -445.7597 -445.7597 C++ Note: df102 -2.098516 -1.409538e-07 C++ Note: df103 -123043.1 -1.409539e-07 C++ Note: df104 0.01186962 -16.47844 C++ Note: Checking Deviance 719.5194 C++ Note: df105 1.705513e-05 0.9999989 C++ Note: df106 212.4166 3.162453e+09 C++ Note: df101 -445.76 -445.76 C++ Note: df102 -2.09852 -1.40954e-07 C++ Note: df103 -123043 -1.40954e-07 C++ Note: df104 0.0118696 -16.4784 C++ Note: Checking Deviance 719.519 C++ Note: df105 1.70551e-05 0.999999 C++ Note: df106 212.417 3.16245e+09 C++ Note: df501 -445.7597 C++ Note: df504 0.01186962 -16.47844 Error: Atleast one parameter must be free Warning: rmin and rmax lists not equal size, defaulting to lin and loglin min/max values C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 1 C++ Note: df99,25,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 2 C++ Note: values checked 0.01 -15 C++ Note: sums checked 6437.949 3328.001 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6437.949 3328.001 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6437.949 3328.001 C++ Note: df99,534,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: START_POIS_GUESS C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 1 C++ Note: df99,25,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 2 in guess 0 C++ Note: values checked 0.01 -15 C++ Note: sums checked 6437.95 3328 C++ Note: derivs checked 3813.95 0.000939732 C++ Note: second derivs checked 3813.95 0.000939732 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6437.95 3328 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6437.95 3328 C++ Note: risk checked 9787.82 C++ Note: risk1 checked 6011.82 0.000944651 C++ Note: risk2 checked 6011.82 0.000944651 C++ Note: df101 -493394 -493394 C++ Note: df102 -303241 -0.047634 C++ Note: df103 -303274 -0.047634 C++ Note: df104 0.01 -15 C++ Note: Checking Deviance 986616 C++ Note: df105 0.999891 1 C++ Note: df106 1.62707 1.0358e+07 C++ Note: Starting Halves C++ Note: df501 -493394.2 C++ Note: df504 0.01 -15 C++ Note: values checked -0.739918 -15.3574 C++ Note: sums checked 4425.73 3328 C++ Note: derivs checked 1801.73 0.000657348 C++ Note: second derivs checked 1801.73 0.000657348 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 4425.73 3328 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 4425.73 3328 C++ Note: risk checked 6616.01 C++ Note: risk1 checked 2840.01 0.000478342 C++ Note: risk2 checked 2840.01 0.000478342 C++ Note: df101 -333413 -333413 C++ Note: df102 -143235 -0.0241165 C++ Note: df103 -143268 -0.0241165 C++ Note: df104 -0.739918 -15.3574 C++ Note: Checking Deviance 666655 C++ Note: df105 0.99977 1 C++ Note: df106 2.32774 1.38251e+07 C++ Note: df100 5170 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 5219 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -333413.3 -333413.3 C++ Note: df102 -143235 -0.02411648 C++ Note: df103 -143268 -0.02411648 C++ Note: df104 -0.7399184 -15.35738 C++ Note: Checking Deviance 666654.6 C++ Note: df105 0.9997697 1 C++ Note: df106 2.327736 1.382512e+07 C++ Note: Starting Halves C++ Note: df501 -333413.3 C++ Note: df504 -0.7399184 -15.35738 C++ Note: values checked -1.48975 -15.8512 C++ Note: sums checked 3475.22 3328 C++ Note: derivs checked 851.224 0.000401193 C++ Note: second derivs checked 851.224 0.000401193 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 3475.22 3328 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 3475.22 3328 C++ Note: risk checked 5117.76 C++ Note: risk1 checked 1341.76 0.000239343 C++ Note: risk2 checked 1341.76 0.000239343 C++ Note: df101 -257857 -257857 C++ Note: df102 -67653.7 -0.0120654 C++ Note: df103 -67686.7 -0.0120654 C++ Note: df104 -1.48975 -15.8512 C++ Note: Checking Deviance 515541 C++ Note: df105 0.999512 1 C++ Note: df106 3.81142 2.13716e+07 C++ Note: df100 7925 1 2 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 7973 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -257856.7 -257856.7 C++ Note: df102 -67653.71 -0.01206537 C++ Note: df103 -67686.71 -0.01206537 C++ Note: df104 -1.489746 -15.85115 C++ Note: Checking Deviance 515541.4 C++ Note: df105 0.9995125 1 C++ Note: df106 3.81142 2.137163e+07 C++ Note: Starting Halves C++ Note: df501 -257856.7 C++ Note: df504 -1.489746 -15.85115 C++ Note: values checked -2.23938 -16.4535 C++ Note: sums checked 3026.24 3328 C++ Note: derivs checked 402.237 0.00021966 C++ Note: second derivs checked 402.237 0.00021966 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 3026.24 3328 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 3026.24 3328 C++ Note: risk checked 4410.03 C++ Note: risk1 checked 634.034 0.000117441 C++ Note: risk2 checked 634.034 0.000117441 C++ Note: df101 -222179 -222179 C++ Note: df102 -31951.6 -0.00591976 C++ Note: df103 -31984.6 -0.00591976 C++ Note: df104 -2.23938 -16.4535 C++ Note: Checking Deviance 444187 C++ Note: df105 0.998968 1 C++ Note: df106 6.95362 3.75318e+07 C++ Note: df100 10561 1 3 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 10609 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -222179.4 -222179.4 C++ Note: df102 -31951.63 -0.005919756 C++ Note: df103 -31984.63 -0.005919756 C++ Note: df104 -2.23938 -16.45351 C++ Note: Checking Deviance 444186.7 C++ Note: df105 0.9989683 1 C++ Note: df106 6.953616 3.753185e+07 C++ Note: Starting Halves C++ Note: df501 -222179.4 C++ Note: df504 -2.23938 -16.45351 C++ Note: values checked -2.98861 -17.1257 C++ Note: sums checked 2814.15 3328 C++ Note: derivs checked 190.15 0.000112156 C++ Note: second derivs checked 190.15 0.000112156 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 2814.15 3328 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 2814.15 3328 C++ Note: risk checked 4075.73 C++ Note: risk1 checked 299.728 5.66831e-05 C++ Note: risk2 checked 299.728 5.66831e-05 C++ Note: df101 -205340 -205340 C++ Note: df102 -15087.2 -0.00285705 C++ Note: df103 -15120.2 -0.00285705 C++ Note: df104 -2.98861 -17.1257 C++ Note: Checking Deviance 410507 C++ Note: df105 0.997817 1 C++ Note: df106 13.6102 7.18712e+07 C++ Note: df100 13191 1 4 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 13239 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -205339.6 -205339.6 C++ Note: df102 -15087.16 -0.002857052 C++ Note: df103 -15120.16 -0.002857052 C++ Note: df104 -2.988606 -17.1257 C++ Note: Checking Deviance 410507.3 C++ Note: df105 0.9978175 1 C++ Note: df106 13.61022 7.187117e+07 C++ Note: Starting Halves C++ Note: df501 -205339.6 C++ Note: df504 -2.988606 -17.1257 C++ Note: values checked -3.73697 -17.8368 C++ Note: sums checked 2713.97 3328 C++ Note: derivs checked 89.9678 5.50787e-05 C++ Note: second derivs checked 89.9678 5.50787e-05 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 2713.97 3328 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 2713.97 3328 C++ Note: risk checked 3917.81 C++ Note: risk1 checked 141.814 2.70754e-05 C++ Note: risk2 checked 141.814 2.70754e-05 C++ Note: df101 -197398 -197398 C++ Note: df102 -7120.96 -0.00136467 C++ Note: df103 -7153.96 -0.00136467 C++ Note: df104 -3.73697 -17.8368 C++ Note: Checking Deviance 394624 C++ Note: df105 0.995387 1 C++ Note: df106 27.7207 1.44649e+08 C++ Note: df100 15796 1 5 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 15844 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -197398.1 -197398.1 C++ Note: df102 -7120.961 -0.001364671 C++ Note: df103 -7153.961 -0.001364671 C++ Note: df104 -3.736969 -17.83683 C++ Note: Checking Deviance 394624.2 C++ Note: df105 0.9953872 1 C++ Note: df106 27.72071 1.446488e+08 C++ Note: df101 -197398 -197398 C++ Note: df102 -7120.96 -0.00136467 C++ Note: df103 -7153.96 -0.00136467 C++ Note: df104 -3.73697 -17.8368 C++ Note: Checking Deviance 394624 C++ Note: df105 0.995387 1 C++ Note: df106 27.7207 1.44649e+08 C++ Note: ending guess 0 C++ Note: df501 -197398.1 C++ Note: df504 -3.736969 -17.83683 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -3.736969 -17.83683, -197398.1<-- Best Guess C++ Note: starting subterms 2 in best guess 0 C++ Note: values checked -3.73697 -17.8368 C++ Note: sums checked 2713.97 3328 C++ Note: derivs checked 89.9678 5.50787e-05 C++ Note: second derivs checked 89.9678 5.50787e-05 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 2713.97 3328 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 2713.97 3328 C++ Note: risk checked 3917.81 C++ Note: risk1 checked 141.814 2.70754e-05 C++ Note: risk2 checked 141.814 2.70754e-05 C++ Note: Made Risk Side Lists C++ Note: df101 -197398 -197398 C++ Note: df102 -7120.96 -0.00136467 C++ Note: df103 -7153.96 -0.00136467 C++ Note: df104 -3.73697 -17.8368 C++ Note: Checking Deviance 394624 C++ Note: df105 0.995387 1 C++ Note: df106 27.7207 1.44649e+08 C++ Note: Starting Halves C++ Note: df501 -197398.1 C++ Note: df504 -3.736969 -17.83683 C++ Note: values checked -4.48351 -18.568 C++ Note: sums checked 2666.65 3328 C++ Note: derivs checked 42.645 2.65127e-05 C++ Note: second derivs checked 42.645 2.65127e-05 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 2666.65 3328 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 2666.65 3328 C++ Note: risk checked 3843.22 C++ Note: risk1 checked 67.2201 1.286e-05 C++ Note: risk2 checked 67.2201 1.286e-05 C++ Note: df101 -193660 -193660 C++ Note: df102 -3358 -0.000648169 C++ Note: df103 -3391 -0.000648169 C++ Note: df104 -4.48351 -18.568 C++ Note: Checking Deviance 387148 C++ Note: df105 0.990268 1 C++ Note: df106 57.6711 2.9878e+08 C++ Note: df100 21717 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 21765 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -193659.8 -193659.8 C++ Note: df102 -3358.003 -0.0006481694 C++ Note: df103 -3391.003 -0.0006481694 C++ Note: df104 -4.48351 -18.56797 C++ Note: Checking Deviance 387147.6 C++ Note: df105 0.9902684 1 C++ Note: df106 57.67112 2.987796e+08 C++ Note: df101 -193660 -193660 C++ Note: df102 -3358 -0.000648169 C++ Note: df103 -3391 -0.000648169 C++ Note: df104 -4.48351 -18.568 C++ Note: Checking Deviance 387148 C++ Note: df105 0.990268 1 C++ Note: df106 57.6711 2.9878e+08 C++ Note: df501 -193659.8 C++ Note: df504 -4.48351 -18.56797 Error: guesses_control and model_control have different strata options Warning: rmin and rmax lists not equal size, defaulting to lin and loglin min/max values C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 1 C++ Note: df99,24,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 2 C++ Note: values checked 0.01 -15 C++ Note: sums checked 6437.949 3328.001 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6437.949 3328.001 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6437.949 3328.001 C++ Note: df99,424,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: START_POIS_GUESS C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 1 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 2 in guess 0 C++ Note: values checked 0.01 -15 C++ Note: sums checked 6437.95 3328 C++ Note: derivs checked 3813.95 0.000939732 C++ Note: second derivs checked 3813.95 0.000939732 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6437.95 3328 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6437.95 3328 C++ Note: risk checked 9787.82 C++ Note: risk1 checked 6011.82 0.000944651 C++ Note: risk2 checked 6011.82 0.000944651 C++ Note: df101 -493394 -493394 C++ Note: df102 -303241 -0.047634 C++ Note: df103 -303274 -0.047634 C++ Note: df104 0.01 -15 C++ Note: Checking Deviance 986616 C++ Note: df105 0.999891 1 C++ Note: df106 1.62707 1.0358e+07 C++ Note: Starting Halves C++ Note: df501 -493394.2 C++ Note: df504 0.01 -15 C++ Note: values checked -0.739918 -15.3574 C++ Note: sums checked 4425.73 3328 C++ Note: derivs checked 1801.73 0.000657348 C++ Note: second derivs checked 1801.73 0.000657348 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 4425.73 3328 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 4425.73 3328 C++ Note: risk checked 6616.01 C++ Note: risk1 checked 2840.01 0.000478342 C++ Note: risk2 checked 2840.01 0.000478342 C++ Note: df101 -333413 -333413 C++ Note: df102 -143235 -0.0241165 C++ Note: df103 -143268 -0.0241165 C++ Note: df104 -0.739918 -15.3574 C++ Note: Checking Deviance 666655 C++ Note: df105 0.99977 1 C++ Note: df106 2.32774 1.38251e+07 C++ Note: df100 5049 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 5097 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -333413.3 -333413.3 C++ Note: df102 -143235 -0.02411648 C++ Note: df103 -143268 -0.02411648 C++ Note: df104 -0.7399184 -15.35738 C++ Note: Checking Deviance 666654.6 C++ Note: df105 0.9997697 1 C++ Note: df106 2.327736 1.382512e+07 C++ Note: Starting Halves C++ Note: df501 -333413.3 C++ Note: df504 -0.7399184 -15.35738 C++ Note: values checked -1.48975 -15.8512 C++ Note: sums checked 3475.22 3328 C++ Note: derivs checked 851.224 0.000401193 C++ Note: second derivs checked 851.224 0.000401193 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 3475.22 3328 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 3475.22 3328 C++ Note: risk checked 5117.76 C++ Note: risk1 checked 1341.76 0.000239343 C++ Note: risk2 checked 1341.76 0.000239343 C++ Note: df101 -257857 -257857 C++ Note: df102 -67653.7 -0.0120654 C++ Note: df103 -67686.7 -0.0120654 C++ Note: df104 -1.48975 -15.8512 C++ Note: Checking Deviance 515541 C++ Note: df105 0.999512 1 C++ Note: df106 3.81142 2.13716e+07 C++ Note: df100 7680 1 2 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 7727 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -257856.7 -257856.7 C++ Note: df102 -67653.71 -0.01206537 C++ Note: df103 -67686.71 -0.01206537 C++ Note: df104 -1.489746 -15.85115 C++ Note: Checking Deviance 515541.4 C++ Note: df105 0.9995125 1 C++ Note: df106 3.81142 2.137163e+07 C++ Note: Starting Halves C++ Note: df501 -257856.7 C++ Note: df504 -1.489746 -15.85115 C++ Note: values checked -2.23938 -16.4535 C++ Note: sums checked 3026.24 3328 C++ Note: derivs checked 402.237 0.00021966 C++ Note: second derivs checked 402.237 0.00021966 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 3026.24 3328 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 3026.24 3328 C++ Note: risk checked 4410.03 C++ Note: risk1 checked 634.034 0.000117441 C++ Note: risk2 checked 634.034 0.000117441 C++ Note: df101 -222179 -222179 C++ Note: df102 -31951.6 -0.00591976 C++ Note: df103 -31984.6 -0.00591976 C++ Note: df104 -2.23938 -16.4535 C++ Note: Checking Deviance 444187 C++ Note: df105 0.998968 1 C++ Note: df106 6.95362 3.75318e+07 C++ Note: df100 10306 1 3 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 10354 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -222179.4 -222179.4 C++ Note: df102 -31951.63 -0.005919756 C++ Note: df103 -31984.63 -0.005919756 C++ Note: df104 -2.23938 -16.45351 C++ Note: Checking Deviance 444186.7 C++ Note: df105 0.9989683 1 C++ Note: df106 6.953616 3.753185e+07 C++ Note: Starting Halves C++ Note: df501 -222179.4 C++ Note: df504 -2.23938 -16.45351 C++ Note: values checked -2.98861 -17.1257 C++ Note: sums checked 2814.15 3328 C++ Note: derivs checked 190.15 0.000112156 C++ Note: second derivs checked 190.15 0.000112156 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 2814.15 3328 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 2814.15 3328 C++ Note: risk checked 4075.73 C++ Note: risk1 checked 299.728 5.66831e-05 C++ Note: risk2 checked 299.728 5.66831e-05 C++ Note: df101 -205340 -205340 C++ Note: df102 -15087.2 -0.00285705 C++ Note: df103 -15120.2 -0.00285705 C++ Note: df104 -2.98861 -17.1257 C++ Note: Checking Deviance 410507 C++ Note: df105 0.997817 1 C++ Note: df106 13.6102 7.18712e+07 C++ Note: df100 12914 1 4 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 12962 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -205339.6 -205339.6 C++ Note: df102 -15087.16 -0.002857052 C++ Note: df103 -15120.16 -0.002857052 C++ Note: df104 -2.988606 -17.1257 C++ Note: Checking Deviance 410507.3 C++ Note: df105 0.9978175 1 C++ Note: df106 13.61022 7.187117e+07 C++ Note: Starting Halves C++ Note: df501 -205339.6 C++ Note: df504 -2.988606 -17.1257 C++ Note: values checked -3.73697 -17.8368 C++ Note: sums checked 2713.97 3328 C++ Note: derivs checked 89.9678 5.50787e-05 C++ Note: second derivs checked 89.9678 5.50787e-05 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 2713.97 3328 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 2713.97 3328 C++ Note: risk checked 3917.81 C++ Note: risk1 checked 141.814 2.70754e-05 C++ Note: risk2 checked 141.814 2.70754e-05 C++ Note: df101 -197398 -197398 C++ Note: df102 -7120.96 -0.00136467 C++ Note: df103 -7153.96 -0.00136467 C++ Note: df104 -3.73697 -17.8368 C++ Note: Checking Deviance 394624 C++ Note: df105 0.995387 1 C++ Note: df106 27.7207 1.44649e+08 C++ Note: df100 15522 1 5 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 15569 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -197398.1 -197398.1 C++ Note: df102 -7120.961 -0.001364671 C++ Note: df103 -7153.961 -0.001364671 C++ Note: df104 -3.736969 -17.83683 C++ Note: Checking Deviance 394624.2 C++ Note: df105 0.9953872 1 C++ Note: df106 27.72071 1.446488e+08 C++ Note: df101 -197398 -197398 C++ Note: df102 -7120.96 -0.00136467 C++ Note: df103 -7153.96 -0.00136467 C++ Note: df104 -3.73697 -17.8368 C++ Note: Checking Deviance 394624 C++ Note: df105 0.995387 1 C++ Note: df106 27.7207 1.44649e+08 C++ Note: ending guess 0 C++ Note: df501 -197398.1 C++ Note: df504 -3.736969 -17.83683 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -3.736969 -17.83683, -197398.1<-- Best Guess C++ Note: starting subterms 2 in best guess 0 C++ Note: values checked -3.73697 -17.8368 C++ Note: sums checked 2713.97 3328 C++ Note: derivs checked 89.9678 5.50787e-05 C++ Note: second derivs checked 89.9678 5.50787e-05 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 2713.97 3328 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 2713.97 3328 C++ Note: risk checked 3917.81 C++ Note: risk1 checked 141.814 2.70754e-05 C++ Note: risk2 checked 141.814 2.70754e-05 C++ Note: Made Risk Side Lists C++ Note: df101 -197398 -197398 C++ Note: df102 -7120.96 -0.00136467 C++ Note: df103 -7153.96 -0.00136467 C++ Note: df104 -3.73697 -17.8368 C++ Note: Checking Deviance 394624 C++ Note: df105 0.995387 1 C++ Note: df106 27.7207 1.44649e+08 C++ Note: Starting Halves C++ Note: df501 -197398.1 C++ Note: df504 -3.736969 -17.83683 C++ Note: values checked -4.48351 -18.568 C++ Note: sums checked 2666.65 3328 C++ Note: derivs checked 42.645 2.65127e-05 C++ Note: second derivs checked 42.645 2.65127e-05 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 2666.65 3328 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 2666.65 3328 C++ Note: risk checked 3843.22 C++ Note: risk1 checked 67.2201 1.286e-05 C++ Note: risk2 checked 67.2201 1.286e-05 C++ Note: df101 -193660 -193660 C++ Note: df102 -3358 -0.000648169 C++ Note: df103 -3391 -0.000648169 C++ Note: df104 -4.48351 -18.568 C++ Note: Checking Deviance 387148 C++ Note: df105 0.990268 1 C++ Note: df106 57.6711 2.9878e+08 C++ Note: df100 21471 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 21519 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -193659.8 -193659.8 C++ Note: df102 -3358.003 -0.0006481694 C++ Note: df103 -3391.003 -0.0006481694 C++ Note: df104 -4.48351 -18.56797 C++ Note: Checking Deviance 387147.6 C++ Note: df105 0.9902684 1 C++ Note: df106 57.67112 2.987796e+08 C++ Note: df101 -193660 -193660 C++ Note: df102 -3358 -0.000648169 C++ Note: df103 -3391 -0.000648169 C++ Note: df104 -4.48351 -18.568 C++ Note: Checking Deviance 387148 C++ Note: df105 0.990268 1 C++ Note: df106 57.6711 2.9878e+08 C++ Note: df501 -193659.8 C++ Note: df504 -4.48351 -18.56797 Error: Atleast one parameter must be free Warning: rmin and rmax lists not equal size, defaulting to lin and loglin min/max values C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 1 C++ Note: df99,25,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 2 C++ Note: values checked 0.01 -15 C++ Note: sums checked 6437.949 0.001957775 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6437.949 0.001957775 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6437.949 0.001957775 C++ Note: df99,426,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: START_POIS_GUESS C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 1 C++ Note: df99,25,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 2 in guess 0 C++ Note: values checked 0.01 -15 C++ Note: sums checked 6437.95 0.00195777 C++ Note: derivs checked 3813.95 0.00195777 C++ Note: second derivs checked 3813.95 0.00195777 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6437.95 0.00195777 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6437.95 0.00195777 C++ Note: risk checked 6437.95 C++ Note: risk1 checked 3813.95 0.00196938 C++ Note: risk2 checked 3813.95 0.00196938 C++ Note: df101 -324424 -324424 C++ Note: df102 -192366 -0.0993192 C++ Note: df103 -192399 -0.0993192 C++ Note: df104 0.01 -15 C++ Note: Checking Deviance 648676 C++ Note: df105 0.999828 1 C++ Note: df106 1.68649 3.26648e+06 C++ Note: Starting Halves C++ Note: df501 -324424.1 C++ Note: df504 0.01 -15 C++ Note: values checked -0.739871 -15.3056 C++ Note: sums checked 4425.81 0.00144221 C++ Note: derivs checked 1801.81 0.00144221 C++ Note: second derivs checked 1801.81 0.00144221 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 4425.81 0.00144221 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 4425.81 0.00144221 C++ Note: risk checked 4425.82 C++ Note: risk1 checked 1801.81 0.000997333 C++ Note: risk2 checked 1801.81 0.000997333 C++ Note: df101 -222944 -222944 C++ Note: df102 -90861.8 -0.0502905 C++ Note: df103 -90894.8 -0.0502905 C++ Note: df104 -0.739871 -15.3056 C++ Note: Checking Deviance 445716 C++ Note: df105 0.999637 1 C++ Note: df106 2.45366 4.43313e+06 C++ Note: df100 5018 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 5066 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -222944.2 -222944.2 C++ Note: df102 -90861.77 -0.05029052 C++ Note: df103 -90894.77 -0.05029052 C++ Note: df104 -0.7398713 -15.30563 C++ Note: Checking Deviance 445716.4 C++ Note: df105 0.9996369 1 C++ Note: df106 2.453663 4433125 C++ Note: Starting Halves C++ Note: df501 -222944.2 C++ Note: df504 -0.7398713 -15.30563 C++ Note: values checked -1.4896 -15.7503 C++ Note: sums checked 3475.35 0.000924527 C++ Note: derivs checked 851.349 0.000924527 C++ Note: second derivs checked 851.349 0.000924527 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 3475.35 0.000924527 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 3475.35 0.000924527 C++ Note: risk checked 3475.35 C++ Note: risk1 checked 851.349 0.00050204 C++ Note: risk2 checked 851.349 0.00050204 C++ Note: df101 -175021 -175021 C++ Note: df102 -42914.3 -0.0253124 C++ Note: df103 -42947.3 -0.0253124 C++ Note: df104 -1.4896 -15.7503 C++ Note: Checking Deviance 349871 C++ Note: df105 0.999232 1 C++ Note: df106 4.07839 6.91445e+06 C++ Note: df100 7671 1 2 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 7718 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -175021.5 -175021.5 C++ Note: df102 -42914.34 -0.02531243 C++ Note: df103 -42947.34 -0.02531243 C++ Note: df104 -1.489599 -15.75028 C++ Note: Checking Deviance 349871 C++ Note: df105 0.9992316 1 C++ Note: df106 4.078392 6914448 C++ Note: Starting Halves C++ Note: df501 -175021.5 C++ Note: df504 -1.489599 -15.75028 C++ Note: values checked -2.23902 -16.3166 C++ Note: sums checked 3026.38 0.000524773 C++ Note: derivs checked 402.38 0.000524773 C++ Note: second derivs checked 402.38 0.000524773 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 3026.38 0.000524773 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 3026.38 0.000524773 C++ Note: risk checked 3026.38 C++ Note: risk1 checked 402.38 0.00024815 C++ Note: risk2 checked 402.38 0.00024815 C++ Note: df101 -152397 -152397 C++ Note: df102 -20265.6 -0.0125105 C++ Note: df103 -20298.6 -0.0125105 C++ Note: df104 -2.23902 -16.3166 C++ Note: Checking Deviance 304623 C++ Note: df105 0.998374 1 C++ Note: df106 7.52001 1.21815e+07 C++ Note: df100 10298 1 3 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 10346 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -152397.5 -152397.5 C++ Note: df102 -20265.58 -0.01251054 C++ Note: df103 -20298.58 -0.01251054 C++ Note: df104 -2.239023 -16.3166 C++ Note: Checking Deviance 304622.9 C++ Note: df105 0.9983743 1 C++ Note: df106 7.520014 1.218152e+07 C++ Note: Starting Halves C++ Note: df501 -152397.5 C++ Note: df504 -2.239023 -16.3166 C++ Note: values checked -2.9878 -16.967 C++ Note: sums checked 2814.3 0.000273851 C++ Note: derivs checked 190.303 0.000273851 C++ Note: second derivs checked 190.303 0.000273851 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 2814.3 0.000273851 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 2814.3 0.000273851 C++ Note: risk checked 2814.3 C++ Note: risk1 checked 190.303 0.000120422 C++ Note: risk2 checked 190.303 0.000120422 C++ Note: df101 -141724 -141724 C++ Note: df102 -9567.07 -0.0060708 C++ Note: df103 -9600.07 -0.0060708 C++ Note: df104 -2.9878 -16.967 C++ Note: Checking Deviance 283275 C++ Note: df105 0.996563 1 C++ Note: df106 14.8137 2.33451e+07 C++ Note: df100 12912 1 4 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 12960 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -141723.6 -141723.6 C++ Note: df102 -9567.07 -0.006070799 C++ Note: df103 -9600.07 -0.006070799 C++ Note: df104 -2.987803 -16.96698 C++ Note: Checking Deviance 283275.3 C++ Note: df105 0.9965625 1 C++ Note: df106 14.81369 2.334514e+07 C++ Note: Starting Halves C++ Note: df501 -141723.6 C++ Note: df504 -2.987803 -16.96698 C++ Note: values checked -3.73523 -17.6664 C++ Note: sums checked 2714.12 0.000136068 C++ Note: derivs checked 90.1248 0.000136068 C++ Note: second derivs checked 90.1248 0.000136068 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 2714.12 0.000136068 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 2714.12 0.000136068 C++ Note: risk checked 2714.12 C++ Note: risk1 checked 90.1248 5.77042e-05 C++ Note: risk2 checked 90.1248 5.77042e-05 C++ Note: df101 -136695 -136695 C++ Note: df102 -4513.46 -0.00290896 C++ Note: df103 -4546.46 -0.00290896 C++ Note: df104 -3.73523 -17.6664 C++ Note: Checking Deviance 273217 C++ Note: df105 0.992742 1 C++ Note: df106 30.286 4.6991e+07 C++ Note: df100 15546 1 5 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 15594 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -136694.7 -136694.7 C++ Note: df102 -4513.458 -0.002908957 C++ Note: df103 -4546.458 -0.002908957 C++ Note: df104 -3.735225 -17.66641 C++ Note: Checking Deviance 273217.4 C++ Note: df105 0.9927416 1 C++ Note: df106 30.28602 4.699096e+07 C++ Note: df101 -136695 -136695 C++ Note: df102 -4513.46 -0.00290896 C++ Note: df103 -4546.46 -0.00290896 C++ Note: df104 -3.73523 -17.6664 C++ Note: Checking Deviance 273217 C++ Note: df105 0.992742 1 C++ Note: df106 30.286 4.6991e+07 C++ Note: ending guess 0 C++ Note: df501 -136694.7 C++ Note: df504 -3.735225 -17.66641 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -3.735225 -17.66641, -136694.7<-- Best Guess C++ Note: starting subterms 2 in best guess 0 C++ Note: values checked -3.73523 -17.6664 C++ Note: sums checked 2714.12 0.000136068 C++ Note: derivs checked 90.1248 0.000136068 C++ Note: second derivs checked 90.1248 0.000136068 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 2714.12 0.000136068 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 2714.12 0.000136068 C++ Note: risk checked 2714.12 C++ Note: risk1 checked 90.1248 5.77042e-05 C++ Note: risk2 checked 90.1248 5.77042e-05 C++ Note: Made Risk Side Lists C++ Note: df101 -136695 -136695 C++ Note: df102 -4513.46 -0.00290896 C++ Note: df103 -4546.46 -0.00290896 C++ Note: df104 -3.73523 -17.6664 C++ Note: Checking Deviance 273217 C++ Note: df105 0.992742 1 C++ Note: df106 30.286 4.6991e+07 C++ Note: Starting Halves C++ Note: df501 -136694.7 C++ Note: df504 -3.735225 -17.66641 C++ Note: values checked -4.47978 -18.3917 C++ Note: sums checked 2666.8 6.58842e-05 C++ Note: derivs checked 42.8043 6.58842e-05 C++ Note: second derivs checked 42.8043 6.58842e-05 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 2666.8 6.58842e-05 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 2666.8 6.58842e-05 C++ Note: risk checked 2666.8 C++ Note: risk1 checked 42.8043 2.74532e-05 C++ Note: risk2 checked 42.8043 2.74532e-05 C++ Note: df101 -134332 -134332 C++ Note: df102 -2126.32 -0.00138394 C++ Note: df103 -2159.32 -0.00138394 C++ Note: df104 -4.47978 -18.3917 C++ Note: Checking Deviance 268492 C++ Note: df105 0.984717 1 C++ Note: df106 63.1759 9.7065e+07 C++ Note: df100 21613 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df100 21662 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: df101 -134332.1 -134332.1 C++ Note: df102 -2126.318 -0.00138394 C++ Note: df103 -2159.318 -0.00138394 C++ Note: df104 -4.479781 -18.39167 C++ Note: Checking Deviance 268492.2 C++ Note: df105 0.9847174 1 C++ Note: df106 63.17594 9.706499e+07 C++ Note: df101 -134332 -134332 C++ Note: df102 -2126.32 -0.00138394 C++ Note: df103 -2159.32 -0.00138394 C++ Note: df104 -4.47978 -18.3917 C++ Note: Checking Deviance 268492 C++ Note: df105 0.984717 1 C++ Note: df106 63.1759 9.7065e+07 C++ Note: df501 -134332.1 C++ Note: df504 -4.479781 -18.39167 Note: Starting Plot Function Note: Getting Plot Info Note: 2 risk groups Note: 2 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 C++ Note: df99,22,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Grouping Start C++ Note: df100 73 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 C++ Note: sums checked 3.91896 C++ Note: derivs checked 21.9591 C++ Note: second derivs checked 138.335 C++ Note: dose checked 7 C++ Note: non-dose checked 3.91896 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 3.91896 C++ Note: risk checked 3.91896 C++ Note: risk1 checked 21.9591 C++ Note: risk2 checked 138.335 C++ Note: Made Risk Side Lists C++ Note: riskr checked 1.11965 C++ Note: risk1r checked 6.27591 C++ Note: risk2r checked 39.4822 C++ Note: riskl checked 1.11965 C++ Note: risk1l checked 6.27591 C++ Note: risk2l checked 39.4822 C++ Note: df101 0 C++ Note: df102 0 C++ Note: df103 0 C++ Note: df104 -0.1 C++ Note: df105 nan C++ Note: df106 nan C++ Note: riskr checked 1.11965 C++ Note: risk1r checked 6.27591 C++ Note: risk2r checked 39.4822 C++ Note: riskl checked 1.11965 C++ Note: risk1l checked 6.27591 C++ Note: risk2l checked 39.4822 C++ Note: df101 0 C++ Note: df102 0 C++ Note: df103 0 C++ Note: df104 -0.1 C++ Note: df105 nan C++ Note: df106 nan C++ Note: ending guess 0 C++ Note: df501 0 C++ Note: df504 -0.1 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1, 0<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.1 C++ Note: sums checked 3.91896 C++ Note: derivs checked 21.9591 C++ Note: second derivs checked 138.335 C++ Note: dose checked 7 C++ Note: non-dose checked 3.91896 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 3.91896 C++ Note: risk checked 3.91896 C++ Note: risk1 checked 21.9591 C++ Note: risk2 checked 138.335 C++ Note: Made Risk Side Lists C++ Note: riskr checked 1.11965 C++ Note: risk1r checked 6.27591 C++ Note: risk2r checked 39.4822 C++ Note: riskl checked 1.11965 C++ Note: risk1l checked 6.27591 C++ Note: risk2l checked 39.4822 C++ Note: df101 0 C++ Note: df102 0 C++ Note: df103 0 C++ Note: df104 -0.1 C++ Note: df105 nan C++ Note: df106 nan C++ Note: riskr checked 1.11965 C++ Note: risk1r checked 6.27591 C++ Note: risk2r checked 39.4822 C++ Note: riskl checked 1.11965 C++ Note: risk1l checked 6.27591 C++ Note: risk2l checked 39.4822 C++ Note: df101 0 C++ Note: df102 0 C++ Note: df103 0 C++ Note: df104 -0.1 C++ Note: df105 nan C++ Note: df106 nan C++ Note: Exiting Regression C++ Note: df501 0 C++ Note: df504 -0.1 Note: starting ph_plot Note: nonStratified survival curve calculation C++ Note: START_PLOT C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Term checked 0 C++ Note: df99,21,Starting C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: values checked -0.1 C++ Note: sums checked 3.91896 C++ Note: derivs checked 21.9591 C++ Note: second derivs checked 138.335 C++ Note: dose checked 7 C++ Note: non-dose checked 3.91896 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 3.91896 C++ Note: risk checked 3.91896 C++ Note: risk1 checked 21.9591 C++ Note: risk2 checked 138.335 C++ Note: Grouping Start C++ Note: df100 312 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:15 2024 C++ Note: Made Risk Side Lists C++ Note: riskr checked 1.11965 C++ Note: risk1r checked 6.27591 C++ Note: risk2r checked 39.4822 C++ Note: riskl checked 1.11965 C++ Note: risk1l checked 6.27591 C++ Note: risk2l checked 39.4822 C++ Note: df101 0 C++ Note: df102 0 C++ Note: df103 0 C++ Note: df104 -0.1 C++ Note: df105 nan C++ Note: df106 nan Note: writing survival data Note: Plotting Martingale Residuals Note: Martingale Plot: d Saving 7 x 7 in image Saving 7 x 7 in image Note: Starting Censoring weight Plot Function Note: 908 risk groups Note: 908 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: Term checked 0 0 C++ Note: df99,29,Starting C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: Grouping Start C++ Note: df100 3215 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked 0 0 C++ Note: sums checked 1000 1000 C++ Note: derivs checked 3524.8 501 C++ Note: second derivs checked 19954.8 501 C++ Note: dose checked 1000 C++ Note: non-dose checked 1000 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 1000 C++ Note: risk checked 1000 C++ Note: risk1 checked 3524.8 501 C++ Note: risk2 checked 19954.8 501 C++ Note: Made Risk Side Lists C++ Note: riskr checked 494240 C++ Note: risk1r checked 2.44264e+06 246462 C++ Note: risk2r checked 1.56997e+07 246462 C++ Note: riskl checked 908 C++ Note: risk1l checked 2745.2 459 C++ Note: risk2l checked 13223.2 459 C++ Note: df101 -5536.33 -5536.33 C++ Note: df102 -2409.98 12.6913 C++ Note: df103 -4481.29 -226.265 C++ Note: df104 0 0 C++ Note: df105 0.537787 -0.0560903 C++ Note: df106 2.29725 -436.231 C++ Note: Starting Halves C++ Note: df501 -5536.328 C++ Note: df504 0 0 C++ Note: riskr checked 494240 C++ Note: risk1r checked 2.44264e+06 246462 C++ Note: risk2r checked 1.56997e+07 246462 C++ Note: riskl checked 908 C++ Note: risk1l checked 2745.2 459 C++ Note: risk2l checked 13223.2 459 C++ Note: df101 -5536.33 -5536.33 C++ Note: df102 -2409.98 12.6913 C++ Note: df103 -4481.29 -226.265 C++ Note: df104 0 0 C++ Note: df105 0.537787 -0.0560903 C++ Note: df106 2.29725 -436.231 C++ Note: ending guess 0 C++ Note: df501 -5536.328 C++ Note: df504 0 0 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0 0, -5536.328<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0 0 C++ Note: sums checked 1000 1000 C++ Note: derivs checked 3524.8 501 C++ Note: second derivs checked 19954.8 501 C++ Note: dose checked 1000 C++ Note: non-dose checked 1000 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 1000 C++ Note: risk checked 1000 C++ Note: risk1 checked 3524.8 501 C++ Note: risk2 checked 19954.8 501 C++ Note: Made Risk Side Lists C++ Note: riskr checked 494240 C++ Note: risk1r checked 2.44264e+06 246462 C++ Note: risk2r checked 1.56997e+07 246462 C++ Note: riskl checked 908 C++ Note: risk1l checked 2745.2 459 C++ Note: risk2l checked 13223.2 459 C++ Note: df101 -5536.33 -5536.33 C++ Note: df102 -2409.98 12.6913 C++ Note: df103 -4481.29 -226.265 C++ Note: df104 0 0 C++ Note: df105 0.537787 -0.0560903 C++ Note: df106 2.29725 -436.231 C++ Note: riskr checked 494240 C++ Note: risk1r checked 2.44264e+06 246462 C++ Note: risk2r checked 1.56997e+07 246462 C++ Note: riskl checked 908 C++ Note: risk1l checked 2745.2 459 C++ Note: risk2l checked 13223.2 459 C++ Note: df101 -5536.33 -5536.33 C++ Note: df102 -2409.98 12.6913 C++ Note: df103 -4481.29 -226.265 C++ Note: df104 0 0 C++ Note: df105 0.537787 -0.0560903 C++ Note: df106 2.29725 -436.231 C++ Note: Exiting Regression C++ Note: df501 -5536.328 C++ Note: df504 0 0 C++ Note: START_PLOT C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: Term checked 0 0 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: values checked 0 0 C++ Note: sums checked 1000 1000 C++ Note: derivs checked 3524.8 501 C++ Note: second derivs checked 19954.8 501 C++ Note: dose checked 1000 C++ Note: non-dose checked 1000 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 1000 C++ Note: risk checked 1000 C++ Note: risk1 checked 3524.8 501 C++ Note: risk2 checked 19954.8 501 C++ Note: Grouping Start C++ Note: df100 3499 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: Made Risk Side Lists C++ Note: riskr checked 494240 C++ Note: risk1r checked 2.44264e+06 246462 C++ Note: risk2r checked 1.56997e+07 246462 C++ Note: riskl checked 908 C++ Note: risk1l checked 2745.2 459 C++ Note: risk2l checked 13223.2 459 C++ Note: df101 -5536.33 -5536.33 C++ Note: df102 -2409.98 12.6913 C++ Note: df103 -4481.29 -226.265 C++ Note: df104 0 0 C++ Note: df105 0.537787 -0.0560903 C++ Note: df106 2.29725 -436.231 Saving 7 x 7 in image Note: Starting Censoring weight Plot Function Error: Atleast one parameter must be free Note: Starting Censoring weight Plot Function Error: no events Note: Starting Plot Function Note: Getting Plot Info Note: 3 risk groups Note: 3 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: Term checked 0 C++ Note: df99,24,Starting C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: Grouping Start C++ Note: df100 121 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 C++ Note: sums checked 132.881 C++ Note: derivs checked 68.7704 C++ Note: second derivs checked 47.0839 C++ Note: dose checked 140 C++ Note: non-dose checked 132.881 C++ Note: LIN_non-dose checked 140 C++ Note: PLIN_non-dose checked 140 C++ Note: LOGLIN_non-dose checked 132.881 C++ Note: risk checked 132.881 C++ Note: risk1 checked 68.7704 C++ Note: risk2 checked 47.0839 C++ Note: Made Risk Side Lists C++ Note: riskr checked 56.924 C++ Note: risk1r checked 29.7397 C++ Note: risk2r checked 19.9101 C++ Note: riskl checked 56.924 C++ Note: risk1l checked 29.7397 C++ Note: risk2l checked 19.9101 C++ Note: df101 -179.767 C++ Note: df102 0.452348 C++ Note: df103 -4.54007 C++ Note: df104 -0.1 C++ Note: df105 -0.0996345 C++ Note: df106 -397.408 C++ Note: riskr checked 56.924 C++ Note: risk1r checked 29.7397 C++ Note: risk2r checked 19.9101 C++ Note: riskl checked 56.924 C++ Note: risk1l checked 29.7397 C++ Note: risk2l checked 19.9101 C++ Note: df101 -179.767 C++ Note: df102 0.452348 C++ Note: df103 -4.54007 C++ Note: df104 -0.1 C++ Note: df105 -0.0996345 C++ Note: df106 -397.408 C++ Note: ending guess 0 C++ Note: df501 -179.7665 C++ Note: df504 -0.1 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1, -179.7665<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.1 C++ Note: sums checked 132.881 C++ Note: derivs checked 68.7704 C++ Note: second derivs checked 47.0839 C++ Note: dose checked 140 C++ Note: non-dose checked 132.881 C++ Note: LIN_non-dose checked 140 C++ Note: PLIN_non-dose checked 140 C++ Note: LOGLIN_non-dose checked 132.881 C++ Note: risk checked 132.881 C++ Note: risk1 checked 68.7704 C++ Note: risk2 checked 47.0839 C++ Note: Made Risk Side Lists C++ Note: riskr checked 56.924 C++ Note: risk1r checked 29.7397 C++ Note: risk2r checked 19.9101 C++ Note: riskl checked 56.924 C++ Note: risk1l checked 29.7397 C++ Note: risk2l checked 19.9101 C++ Note: df101 -179.767 C++ Note: df102 0.452348 C++ Note: df103 -4.54007 C++ Note: df104 -0.1 C++ Note: df105 -0.0996345 C++ Note: df106 -397.408 C++ Note: riskr checked 56.924 C++ Note: risk1r checked 29.7397 C++ Note: risk2r checked 19.9101 C++ Note: riskl checked 56.924 C++ Note: risk1l checked 29.7397 C++ Note: risk2l checked 19.9101 C++ Note: df101 -179.767 C++ Note: df102 0.452348 C++ Note: df103 -4.54007 C++ Note: df104 -0.1 C++ Note: df105 -0.0996345 C++ Note: df106 -397.408 C++ Note: Exiting Regression C++ Note: df501 -179.7665 C++ Note: df504 -0.1 C++ Note: START_PLOT C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: Term checked 0 C++ Note: df99,53,Starting C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: values checked -0.1 C++ Note: sums checked 95.2509 C++ Note: dose checked 100 C++ Note: non-dose checked 95.2509 C++ Note: LIN_non-dose checked 100 C++ Note: PLIN_non-dose checked 100 C++ Note: LOGLIN_non-dose checked 95.2509 C++ Note: risk checked 95.2509 Saving 7 x 7 in image Warning: model covariate order changed Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: Term checked 0 0 1 C++ Note: df99,33,Starting C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: Grouping Start C++ Note: df100 273 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: starting subterms 2 in guess 0 C++ Note: values checked 0.426096 0.646539 0.157278 C++ Note: sums checked 7274.1 7274.1 1341.83 C++ Note: derivs checked 4601.97 23182.6 2733.27 C++ Note: second derivs checked 4601.97 82544.2 8524.37 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 7274.1 1341.83 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 7274.1 1341.83 C++ Note: risk checked 17001 C++ Note: risk1 checked 10706.4 54122.7 19625.6 C++ Note: risk2 checked 10706.4 192502 61415.9 C++ Note: Made Risk Side Lists C++ Note: riskr checked 45411.7 C++ Note: risk1r checked 28767.4 144720 52387.3 C++ Note: risk2r checked 28767.4 514964 151495 C++ Note: riskl checked 498.666 C++ Note: risk1l checked 304.226 1582.04 793.308 C++ Note: risk2l checked 304.226 5554.38 2609.55 C++ Note: df101 -124.812 -124.812 -124.812 C++ Note: df102 -0.467622 -22.6674 2.97163 C++ Note: df103 -6.02126 -30.6469 -1.27345 C++ Note: df104 0.426096 0.646539 0.157278 C++ Note: df105 0.0776618 0.739632 -2.33354 C++ Note: df106 266.907 5.50621 -42.001 C++ Note: Starting Halves C++ Note: df501 -124.8115 C++ Note: df504 0.4260961 0.646539 0.1572781 C++ Note: values checked 0.600743 0.0965281 1.15728 C++ Note: sums checked 1773.98 1773.98 32135.8 C++ Note: derivs checked 1194.6 4043.19 134742 C++ Note: second derivs checked 1194.6 12805.3 616015 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 1773.98 32135.8 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 1773.98 32135.8 C++ Note: risk checked 58026.5 C++ Note: risk1 checked 37651.2 135360 236019 C++ Note: risk2 checked 37651.2 427814 1.08252e+06 C++ Note: riskr checked 119495 C++ Note: risk1r checked 76635.5 283568 429089 C++ Note: risk2r checked 76635.5 896488 1.77407e+06 C++ Note: riskl checked 1711.94 C++ Note: risk1l checked 1027.65 4618.5 6140.17 C++ Note: risk2l checked 1027.65 15652.6 24115.3 C++ Note: df101 -118.395 -118.395 -118.395 C++ Note: df102 -0.782638 -0.410558 -4.43759 C++ Note: df103 -5.94091 -49.8573 -9.26764 C++ Note: df104 0.600743 0.0965281 1.15728 C++ Note: df105 0.131737 0.00823466 0.478826 C++ Note: df106 151.277 288.376 26.68 C++ Note: df100 2956 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: riskr checked 119495 C++ Note: risk1r checked 76635.5 283568 429089 C++ Note: risk2r checked 76635.5 896488 1.77407e+06 C++ Note: riskl checked 1711.94 C++ Note: risk1l checked 1027.65 4618.5 6140.17 C++ Note: risk2l checked 1027.65 15652.6 24115.3 C++ Note: df101 -118.395 -118.395 -118.395 C++ Note: df102 -0.782638 -0.410558 -4.43759 C++ Note: df103 -5.94091 -49.8573 -9.26764 C++ Note: df104 0.600743 0.0965281 1.15728 C++ Note: df105 0.131737 0.00823466 0.478826 C++ Note: df106 151.277 288.376 26.68 C++ Note: ending guess 0 C++ Note: df501 -118.395 C++ Note: df504 0.6007434 0.09652814 1.157278 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.6007434 0.09652814 1.157278, -118.395<-- Best Guess C++ Note: starting subterms 2 in best guess 0 C++ Note: values checked 0.600743 0.0965281 1.15728 C++ Note: sums checked 1773.98 1773.98 32135.8 C++ Note: derivs checked 1194.6 4043.19 134742 C++ Note: second derivs checked 1194.6 12805.3 616015 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 1773.98 32135.8 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 1773.98 32135.8 C++ Note: risk checked 58026.5 C++ Note: risk1 checked 37651.2 135360 236019 C++ Note: risk2 checked 37651.2 427814 1.08252e+06 C++ Note: Made Risk Side Lists C++ Note: riskr checked 119495 C++ Note: risk1r checked 76635.5 283568 429089 C++ Note: risk2r checked 76635.5 896488 1.77407e+06 C++ Note: riskl checked 1711.94 C++ Note: risk1l checked 1027.65 4618.5 6140.17 C++ Note: risk2l checked 1027.65 15652.6 24115.3 C++ Note: df101 -118.395 -118.395 -118.395 C++ Note: df102 -0.782638 -0.410558 -4.43759 C++ Note: df103 -5.94091 -49.8573 -9.26764 C++ Note: df104 0.600743 0.0965281 1.15728 C++ Note: df105 0.131737 0.00823466 0.478826 C++ Note: df106 151.277 288.376 26.68 C++ Note: Starting Halves C++ Note: df501 -118.395 C++ Note: df504 0.6007434 0.09652814 1.157278 C++ Note: values checked 0.469257 0.102151 0.78977 C++ Note: sums checked 1647.84 1647.84 7760.94 C++ Note: derivs checked 1060.93 3775.1 27203.7 C++ Note: second derivs checked 1060.93 11977.1 111988 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 1647.84 7760.94 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 1647.84 7760.94 C++ Note: risk checked 14328.5 C++ Note: risk1 checked 8953.84 33119.7 44341.6 C++ Note: risk2 checked 8953.84 104570 182492 C++ Note: riskr checked 34488.8 C++ Note: risk1r checked 21529.9 80578.6 94839.5 C++ Note: risk2r checked 21529.9 254610 351090 C++ Note: riskl checked 470.725 C++ Note: risk1l checked 299.436 1220.36 1425.98 C++ Note: risk2l checked 299.436 4016.13 5259.82 C++ Note: df101 -117.31 -117.31 -117.31 C++ Note: df102 -0.252504 -0.212118 -1.1189 C++ Note: df103 -6.08937 -50.5934 -9.22555 C++ Note: df104 0.469257 0.102151 0.78977 C++ Note: df105 0.0414663 0.00419259 0.121283 C++ Note: df106 464.589 553.044 104.844 C++ Note: df100 6268 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: riskr checked 34488.8 C++ Note: risk1r checked 21529.9 80578.6 94839.5 C++ Note: risk2r checked 21529.9 254610 351090 C++ Note: riskl checked 470.725 C++ Note: risk1l checked 299.436 1220.36 1425.98 C++ Note: risk2l checked 299.436 4016.13 5259.82 C++ Note: df101 -117.31 -117.31 -117.31 C++ Note: df102 -0.252504 -0.212118 -1.1189 C++ Note: df103 -6.08937 -50.5934 -9.22555 C++ Note: df104 0.469257 0.102151 0.78977 C++ Note: df105 0.0414663 0.00419259 0.121283 C++ Note: df106 464.589 553.044 104.844 C++ Note: riskr checked 34488.8 C++ Note: risk1r checked 21529.9 80578.6 94839.5 C++ Note: risk2r checked 21529.9 254610 351090 C++ Note: riskl checked 470.725 C++ Note: risk1l checked 299.436 1220.36 1425.98 C++ Note: risk2l checked 299.436 4016.13 5259.82 C++ Note: df101 -117.31 -117.31 -117.31 C++ Note: df102 -0.252504 -0.212118 -1.1189 C++ Note: df103 -6.08937 -50.5934 -9.22555 C++ Note: df104 0.469257 0.102151 0.78977 C++ Note: df105 0.0414663 0.00419259 0.121283 C++ Note: df106 464.589 553.044 104.844 C++ Note: Exiting Regression C++ Note: df501 -117.3104 C++ Note: df504 0.4692569 0.1021509 0.7897698 Error: Atleast one parameter must be free Warning: model covariate order changed Error: no events Warning: model covariate order changed Note: 26 risk groups Note: Initial starts: 1 , Number of iterations provided: 4 . Colossus requires one more iteration counts than number of guesses (for best guess) C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: Term checked 0 0 1 C++ Note: df99,30,Starting C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: Grouping Start C++ Note: df100 218 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: starting subterms 2 in guess 0 C++ Note: values checked 0.426096 0.646539 0.157278 C++ Note: sums checked 7274.1 7274.1 1341.83 C++ Note: derivs checked 4601.97 23182.6 2733.27 C++ Note: second derivs checked 4601.97 82544.2 8524.37 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 7274.1 1341.83 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 7274.1 1341.83 C++ Note: risk checked 17001 C++ Note: risk1 checked 10706.4 54122.7 19625.6 C++ Note: risk2 checked 10706.4 192502 61415.9 C++ Note: Made Risk Side Lists C++ Note: riskr checked 45411.7 C++ Note: risk1r checked 28767.4 144720 52387.3 C++ Note: risk2r checked 28767.4 514964 151495 C++ Note: riskl checked 498.666 C++ Note: risk1l checked 304.226 1582.04 793.308 C++ Note: risk2l checked 304.226 5554.38 2609.55 C++ Note: df101 -124.812 -124.812 -124.812 C++ Note: df102 -0.467622 -22.6674 2.97163 C++ Note: df103 -6.02126 -30.6469 -1.27345 C++ Note: df104 0.426096 0.646539 0.157278 C++ Note: df105 0.0776618 0.739632 -2.33354 C++ Note: df106 266.907 5.50621 -42.001 C++ Note: Starting Halves C++ Note: df501 -124.8115 C++ Note: df504 0.4260961 0.646539 0.1572781 C++ Note: values checked 0.600743 0.0965281 1.15728 C++ Note: sums checked 1773.98 1773.98 32135.8 C++ Note: derivs checked 1194.6 4043.19 134742 C++ Note: second derivs checked 1194.6 12805.3 616015 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 1773.98 32135.8 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 1773.98 32135.8 C++ Note: risk checked 58026.5 C++ Note: risk1 checked 37651.2 135360 236019 C++ Note: risk2 checked 37651.2 427814 1.08252e+06 C++ Note: riskr checked 119495 C++ Note: risk1r checked 76635.5 283568 429089 C++ Note: risk2r checked 76635.5 896488 1.77407e+06 C++ Note: riskl checked 1711.94 C++ Note: risk1l checked 1027.65 4618.5 6140.17 C++ Note: risk2l checked 1027.65 15652.6 24115.3 C++ Note: df101 -118.395 -118.395 -118.395 C++ Note: df102 -0.782638 -0.410558 -4.43759 C++ Note: df103 -5.94091 -49.8573 -9.26764 C++ Note: df104 0.600743 0.0965281 1.15728 C++ Note: df105 0.131737 0.00823466 0.478826 C++ Note: df106 151.277 288.376 26.68 C++ Note: df100 2878 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: riskr checked 119495 C++ Note: risk1r checked 76635.5 283568 429089 C++ Note: risk2r checked 76635.5 896488 1.77407e+06 C++ Note: riskl checked 1711.94 C++ Note: risk1l checked 1027.65 4618.5 6140.17 C++ Note: risk2l checked 1027.65 15652.6 24115.3 C++ Note: df101 -118.395 -118.395 -118.395 C++ Note: df102 -0.782638 -0.410558 -4.43759 C++ Note: df103 -5.94091 -49.8573 -9.26764 C++ Note: df104 0.600743 0.0965281 1.15728 C++ Note: df105 0.131737 0.00823466 0.478826 C++ Note: df106 151.277 288.376 26.68 C++ Note: ending guess 0 C++ Note: df501 -118.395 C++ Note: df504 0.6007434 0.09652814 1.157278 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.6007434 0.09652814 1.157278, -118.395<-- Best Guess C++ Note: starting subterms 2 in best guess 0 C++ Note: values checked 0.600743 0.0965281 1.15728 C++ Note: sums checked 1773.98 1773.98 32135.8 C++ Note: derivs checked 1194.6 4043.19 134742 C++ Note: second derivs checked 1194.6 12805.3 616015 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 1773.98 32135.8 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 1773.98 32135.8 C++ Note: risk checked 58026.5 C++ Note: risk1 checked 37651.2 135360 236019 C++ Note: risk2 checked 37651.2 427814 1.08252e+06 C++ Note: Made Risk Side Lists C++ Note: riskr checked 119495 C++ Note: risk1r checked 76635.5 283568 429089 C++ Note: risk2r checked 76635.5 896488 1.77407e+06 C++ Note: riskl checked 1711.94 C++ Note: risk1l checked 1027.65 4618.5 6140.17 C++ Note: risk2l checked 1027.65 15652.6 24115.3 C++ Note: df101 -118.395 -118.395 -118.395 C++ Note: df102 -0.782638 -0.410558 -4.43759 C++ Note: df103 -5.94091 -49.8573 -9.26764 C++ Note: df104 0.600743 0.0965281 1.15728 C++ Note: df105 0.131737 0.00823466 0.478826 C++ Note: df106 151.277 288.376 26.68 C++ Note: Starting Halves C++ Note: df501 -118.395 C++ Note: df504 0.6007434 0.09652814 1.157278 C++ Note: values checked 0.469257 0.102151 0.78977 C++ Note: sums checked 1647.84 1647.84 7760.94 C++ Note: derivs checked 1060.93 3775.1 27203.7 C++ Note: second derivs checked 1060.93 11977.1 111988 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 1647.84 7760.94 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 1647.84 7760.94 C++ Note: risk checked 14328.5 C++ Note: risk1 checked 8953.84 33119.7 44341.6 C++ Note: risk2 checked 8953.84 104570 182492 C++ Note: riskr checked 34488.8 C++ Note: risk1r checked 21529.9 80578.6 94839.5 C++ Note: risk2r checked 21529.9 254610 351090 C++ Note: riskl checked 470.725 C++ Note: risk1l checked 299.436 1220.36 1425.98 C++ Note: risk2l checked 299.436 4016.13 5259.82 C++ Note: df101 -117.31 -117.31 -117.31 C++ Note: df102 -0.252504 -0.212118 -1.1189 C++ Note: df103 -6.08937 -50.5934 -9.22555 C++ Note: df104 0.469257 0.102151 0.78977 C++ Note: df105 0.0414663 0.00419259 0.121283 C++ Note: df106 464.589 553.044 104.844 C++ Note: df100 6134 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: riskr checked 34488.8 C++ Note: risk1r checked 21529.9 80578.6 94839.5 C++ Note: risk2r checked 21529.9 254610 351090 C++ Note: riskl checked 470.725 C++ Note: risk1l checked 299.436 1220.36 1425.98 C++ Note: risk2l checked 299.436 4016.13 5259.82 C++ Note: df101 -117.31 -117.31 -117.31 C++ Note: df102 -0.252504 -0.212118 -1.1189 C++ Note: df103 -6.08937 -50.5934 -9.22555 C++ Note: df104 0.469257 0.102151 0.78977 C++ Note: df105 0.0414663 0.00419259 0.121283 C++ Note: df106 464.589 553.044 104.844 C++ Note: riskr checked 34488.8 C++ Note: risk1r checked 21529.9 80578.6 94839.5 C++ Note: risk2r checked 21529.9 254610 351090 C++ Note: riskl checked 470.725 C++ Note: risk1l checked 299.436 1220.36 1425.98 C++ Note: risk2l checked 299.436 4016.13 5259.82 C++ Note: df101 -117.31 -117.31 -117.31 C++ Note: df102 -0.252504 -0.212118 -1.1189 C++ Note: df103 -6.08937 -50.5934 -9.22555 C++ Note: df104 0.469257 0.102151 0.78977 C++ Note: df105 0.0414663 0.00419259 0.121283 C++ Note: df106 464.589 553.044 104.844 C++ Note: Exiting Regression C++ Note: df501 -117.3104 C++ Note: df504 0.4692569 0.1021509 0.7897698 Warning: model covariate order changed Note: 26 risk groups Note: Initial starts: 3 , Number of iterations provided: 2 . Colossus requires one more iteration counts than number of guesses (for best guess) C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: Term checked 0 0 1 C++ Note: df99,29,Starting C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: Grouping Start C++ Note: df100 198 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: starting subterms 2 in guess 0 C++ Note: values checked 0.426096 0.646539 0.157278 C++ Note: sums checked 7274.1 7274.1 1341.83 C++ Note: derivs checked 4601.97 23182.6 2733.27 C++ Note: second derivs checked 4601.97 82544.2 8524.37 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 7274.1 1341.83 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 7274.1 1341.83 C++ Note: risk checked 17001 C++ Note: risk1 checked 10706.4 54122.7 19625.6 C++ Note: risk2 checked 10706.4 192502 61415.9 C++ Note: Made Risk Side Lists C++ Note: riskr checked 45411.7 C++ Note: risk1r checked 28767.4 144720 52387.3 C++ Note: risk2r checked 28767.4 514964 151495 C++ Note: riskl checked 498.666 C++ Note: risk1l checked 304.226 1582.04 793.308 C++ Note: risk2l checked 304.226 5554.38 2609.55 C++ Note: df101 -124.812 -124.812 -124.812 C++ Note: df102 -0.467622 -22.6674 2.97163 C++ Note: df103 -6.02126 -30.6469 -1.27345 C++ Note: df104 0.426096 0.646539 0.157278 C++ Note: df105 0.0776618 0.739632 -2.33354 C++ Note: df106 266.907 5.50621 -42.001 C++ Note: Starting Halves C++ Note: df501 -124.8115 C++ Note: df504 0.4260961 0.646539 0.1572781 C++ Note: values checked 0.600743 0.0965281 1.15728 C++ Note: sums checked 1773.98 1773.98 32135.8 C++ Note: derivs checked 1194.6 4043.19 134742 C++ Note: second derivs checked 1194.6 12805.3 616015 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 1773.98 32135.8 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 1773.98 32135.8 C++ Note: risk checked 58026.5 C++ Note: risk1 checked 37651.2 135360 236019 C++ Note: risk2 checked 37651.2 427814 1.08252e+06 C++ Note: riskr checked 119495 C++ Note: risk1r checked 76635.5 283568 429089 C++ Note: risk2r checked 76635.5 896488 1.77407e+06 C++ Note: riskl checked 1711.94 C++ Note: risk1l checked 1027.65 4618.5 6140.17 C++ Note: risk2l checked 1027.65 15652.6 24115.3 C++ Note: df101 -118.395 -118.395 -118.395 C++ Note: df102 -0.782638 -0.410558 -4.43759 C++ Note: df103 -5.94091 -49.8573 -9.26764 C++ Note: df104 0.600743 0.0965281 1.15728 C++ Note: df105 0.131737 0.00823466 0.478826 C++ Note: df106 151.277 288.376 26.68 C++ Note: df100 2800 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: riskr checked 119495 C++ Note: risk1r checked 76635.5 283568 429089 C++ Note: risk2r checked 76635.5 896488 1.77407e+06 C++ Note: riskl checked 1711.94 C++ Note: risk1l checked 1027.65 4618.5 6140.17 C++ Note: risk2l checked 1027.65 15652.6 24115.3 C++ Note: df101 -118.395 -118.395 -118.395 C++ Note: df102 -0.782638 -0.410558 -4.43759 C++ Note: df103 -5.94091 -49.8573 -9.26764 C++ Note: df104 0.600743 0.0965281 1.15728 C++ Note: df105 0.131737 0.00823466 0.478826 C++ Note: df106 151.277 288.376 26.68 C++ Note: ending guess 0 C++ Note: df501 -118.395 C++ Note: df504 0.6007434 0.09652814 1.157278 C++ Note: starting subterms 2 in guess 1 C++ Note: values checked 0.426096 0.646539 0.157278 C++ Note: sums checked 7274.1 7274.1 1341.83 C++ Note: derivs checked 4601.97 23182.6 2733.27 C++ Note: second derivs checked 4601.97 82544.2 8524.37 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 7274.1 1341.83 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 7274.1 1341.83 C++ Note: risk checked 17001 C++ Note: risk1 checked 10706.4 54122.7 19625.6 C++ Note: risk2 checked 10706.4 192502 61415.9 C++ Note: Made Risk Side Lists C++ Note: riskr checked 45411.7 C++ Note: risk1r checked 28767.4 144720 52387.3 C++ Note: risk2r checked 28767.4 514964 151495 C++ Note: riskl checked 498.666 C++ Note: risk1l checked 304.226 1582.04 793.308 C++ Note: risk2l checked 304.226 5554.38 2609.55 C++ Note: df101 -124.812 -124.812 -124.812 C++ Note: df102 -0.467622 -22.6674 2.97163 C++ Note: df103 -6.02126 -30.6469 -1.27345 C++ Note: df104 0.426096 0.646539 0.157278 C++ Note: df105 0.0776618 0.739632 -2.33354 C++ Note: df106 266.907 5.50621 -42.001 C++ Note: Starting Halves C++ Note: df501 -118.395 C++ Note: df504 0.6007434 0.09652814 1.157278 C++ Note: values checked 0.600743 0.0965281 1.15728 C++ Note: sums checked 1773.98 1773.98 32135.8 C++ Note: derivs checked 1194.6 4043.19 134742 C++ Note: second derivs checked 1194.6 12805.3 616015 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 1773.98 32135.8 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 1773.98 32135.8 C++ Note: risk checked 58026.5 C++ Note: risk1 checked 37651.2 135360 236019 C++ Note: risk2 checked 37651.2 427814 1.08252e+06 C++ Note: riskr checked 119495 C++ Note: risk1r checked 76635.5 283568 429089 C++ Note: risk2r checked 76635.5 896488 1.77407e+06 C++ Note: riskl checked 1711.94 C++ Note: risk1l checked 1027.65 4618.5 6140.17 C++ Note: risk2l checked 1027.65 15652.6 24115.3 C++ Note: df101 -118.395 -118.395 -118.395 C++ Note: df102 -0.782638 -0.410558 -4.43759 C++ Note: df103 -5.94091 -49.8573 -9.26764 C++ Note: df104 0.600743 0.0965281 1.15728 C++ Note: df105 0.131737 0.00823466 0.478826 C++ Note: df106 151.277 288.376 26.68 C++ Note: df100 6015 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: values checked 0.51342 0.371534 0.657278 C++ Note: sums checked 3370.53 3370.53 4972.82 C++ Note: derivs checked 2201.24 9415.6 15965.6 C++ Note: second derivs checked 2201.24 31933.3 62675 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 3370.53 4972.82 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 3370.53 4972.82 C++ Note: risk checked 20026.8 C++ Note: risk1 checked 12767.6 55905.5 53475 C++ Note: risk2 checked 12767.6 188523 210555 C++ Note: riskr checked 50427.9 C++ Note: risk1r checked 32128.2 141448 121549 C++ Note: risk2r checked 32128.2 477449 432448 C++ Note: riskl checked 694.008 C++ Note: risk1l checked 419.149 2059.62 1976.96 C++ Note: risk2l checked 419.149 7123.47 7257.54 C++ Note: df101 -119.04 -119.04 -119.04 C++ Note: df102 -0.595098 -12.7024 -0.0570081 C++ Note: df103 -5.99518 -41.9658 -9.15921 C++ Note: df104 0.51342 0.371534 0.657278 C++ Note: df105 0.0992627 0.302686 0.00622413 C++ Note: df106 200.035 9.37145 2088.13 C++ Note: df100 7262 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: Changing back to best C++ Note: values checked 0.426096 0.646539 0.157278 C++ Note: sums checked 7274.1 7274.1 1341.83 C++ Note: derivs checked 4601.97 23182.6 2733.27 C++ Note: second derivs checked 4601.97 82544.2 8524.37 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 7274.1 1341.83 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 7274.1 1341.83 C++ Note: risk checked 17001 C++ Note: risk1 checked 10706.4 54122.7 19625.6 C++ Note: risk2 checked 10706.4 192502 61415.9 C++ Note: riskr checked 45411.7 C++ Note: risk1r checked 28767.4 144720 52387.3 C++ Note: risk2r checked 28767.4 514964 151495 C++ Note: riskl checked 498.666 C++ Note: risk1l checked 304.226 1582.04 793.308 C++ Note: risk2l checked 304.226 5554.38 2609.55 C++ Note: df101 -124.812 -124.812 -124.812 C++ Note: df102 -0.467622 -22.6674 2.97163 C++ Note: df103 -6.02126 -30.6469 -1.27345 C++ Note: df104 0.426096 0.646539 0.157278 C++ Note: df105 0.0776618 0.739632 -2.33354 C++ Note: df106 266.907 5.50621 -42.001 C++ Note: ending guess 1 C++ Note: df501 -118.395 C++ Note: df504 0.6007434 0.09652814 1.157278 C++ Note: starting subterms 2 in guess 2 C++ Note: values checked 0.426096 0.646539 0.157278 C++ Note: sums checked 7274.1 7274.1 1341.83 C++ Note: derivs checked 4601.97 23182.6 2733.27 C++ Note: second derivs checked 4601.97 82544.2 8524.37 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 7274.1 1341.83 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 7274.1 1341.83 C++ Note: risk checked 17001 C++ Note: risk1 checked 10706.4 54122.7 19625.6 C++ Note: risk2 checked 10706.4 192502 61415.9 C++ Note: Made Risk Side Lists C++ Note: riskr checked 45411.7 C++ Note: risk1r checked 28767.4 144720 52387.3 C++ Note: risk2r checked 28767.4 514964 151495 C++ Note: riskl checked 498.666 C++ Note: risk1l checked 304.226 1582.04 793.308 C++ Note: risk2l checked 304.226 5554.38 2609.55 C++ Note: df101 -124.812 -124.812 -124.812 C++ Note: df102 -0.467622 -22.6674 2.97163 C++ Note: df103 -6.02126 -30.6469 -1.27345 C++ Note: df104 0.426096 0.646539 0.157278 C++ Note: df105 0.0776618 0.739632 -2.33354 C++ Note: df106 266.907 5.50621 -42.001 C++ Note: Starting Halves C++ Note: df501 -118.395 C++ Note: df504 0.6007434 0.09652814 1.157278 C++ Note: values checked 0.600743 0.0965281 1.15728 C++ Note: sums checked 1773.98 1773.98 32135.8 C++ Note: derivs checked 1194.6 4043.19 134742 C++ Note: second derivs checked 1194.6 12805.3 616015 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 1773.98 32135.8 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 1773.98 32135.8 C++ Note: risk checked 58026.5 C++ Note: risk1 checked 37651.2 135360 236019 C++ Note: risk2 checked 37651.2 427814 1.08252e+06 C++ Note: riskr checked 119495 C++ Note: risk1r checked 76635.5 283568 429089 C++ Note: risk2r checked 76635.5 896488 1.77407e+06 C++ Note: riskl checked 1711.94 C++ Note: risk1l checked 1027.65 4618.5 6140.17 C++ Note: risk2l checked 1027.65 15652.6 24115.3 C++ Note: df101 -118.395 -118.395 -118.395 C++ Note: df102 -0.782638 -0.410558 -4.43759 C++ Note: df103 -5.94091 -49.8573 -9.26764 C++ Note: df104 0.600743 0.0965281 1.15728 C++ Note: df105 0.131737 0.00823466 0.478826 C++ Note: df106 151.277 288.376 26.68 C++ Note: df100 11435 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: values checked 0.51342 0.371534 0.657278 C++ Note: sums checked 3370.53 3370.53 4972.82 C++ Note: derivs checked 2201.24 9415.6 15965.6 C++ Note: second derivs checked 2201.24 31933.3 62675 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 3370.53 4972.82 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 3370.53 4972.82 C++ Note: risk checked 20026.8 C++ Note: risk1 checked 12767.6 55905.5 53475 C++ Note: risk2 checked 12767.6 188523 210555 C++ Note: riskr checked 50427.9 C++ Note: risk1r checked 32128.2 141448 121549 C++ Note: risk2r checked 32128.2 477449 432448 C++ Note: riskl checked 694.008 C++ Note: risk1l checked 419.149 2059.62 1976.96 C++ Note: risk2l checked 419.149 7123.47 7257.54 C++ Note: df101 -119.04 -119.04 -119.04 C++ Note: df102 -0.595098 -12.7024 -0.0570081 C++ Note: df103 -5.99518 -41.9658 -9.15921 C++ Note: df104 0.51342 0.371534 0.657278 C++ Note: df105 0.0992627 0.302686 0.00622413 C++ Note: df106 200.035 9.37145 2088.13 C++ Note: df100 12689 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: Changing back to best C++ Note: values checked 0.426096 0.646539 0.157278 C++ Note: sums checked 7274.1 7274.1 1341.83 C++ Note: derivs checked 4601.97 23182.6 2733.27 C++ Note: second derivs checked 4601.97 82544.2 8524.37 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 7274.1 1341.83 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 7274.1 1341.83 C++ Note: risk checked 17001 C++ Note: risk1 checked 10706.4 54122.7 19625.6 C++ Note: risk2 checked 10706.4 192502 61415.9 C++ Note: riskr checked 45411.7 C++ Note: risk1r checked 28767.4 144720 52387.3 C++ Note: risk2r checked 28767.4 514964 151495 C++ Note: riskl checked 498.666 C++ Note: risk1l checked 304.226 1582.04 793.308 C++ Note: risk2l checked 304.226 5554.38 2609.55 C++ Note: df101 -124.812 -124.812 -124.812 C++ Note: df102 -0.467622 -22.6674 2.97163 C++ Note: df103 -6.02126 -30.6469 -1.27345 C++ Note: df104 0.426096 0.646539 0.157278 C++ Note: df105 0.0776618 0.739632 -2.33354 C++ Note: df106 266.907 5.50621 -42.001 C++ Note: ending guess 2 C++ Note: df501 -118.395 C++ Note: df504 0.6007434 0.09652814 1.157278 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.6007434 0.09652814 1.157278, -118.395<-- Best Guess 1, 0.4260961 0.646539 0.1572781, -124.8115 2, 0.4260961 0.646539 0.1572781, -124.8115 C++ Note: starting subterms 2 in best guess 0 C++ Note: values checked 0.600743 0.0965281 1.15728 C++ Note: sums checked 1773.98 1773.98 32135.8 C++ Note: derivs checked 1194.6 4043.19 134742 C++ Note: second derivs checked 1194.6 12805.3 616015 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 1773.98 32135.8 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 1773.98 32135.8 C++ Note: risk checked 58026.5 C++ Note: risk1 checked 37651.2 135360 236019 C++ Note: risk2 checked 37651.2 427814 1.08252e+06 C++ Note: Made Risk Side Lists C++ Note: riskr checked 119495 C++ Note: risk1r checked 76635.5 283568 429089 C++ Note: risk2r checked 76635.5 896488 1.77407e+06 C++ Note: riskl checked 1711.94 C++ Note: risk1l checked 1027.65 4618.5 6140.17 C++ Note: risk2l checked 1027.65 15652.6 24115.3 C++ Note: df101 -118.395 -118.395 -118.395 C++ Note: df102 -0.782638 -0.410558 -4.43759 C++ Note: df103 -5.94091 -49.8573 -9.26764 C++ Note: df104 0.600743 0.0965281 1.15728 C++ Note: df105 0.131737 0.00823466 0.478826 C++ Note: df106 151.277 288.376 26.68 C++ Note: Starting Halves C++ Note: df501 -118.395 C++ Note: df504 0.6007434 0.09652814 1.157278 C++ Note: values checked 0.469257 0.102151 0.78977 C++ Note: sums checked 1647.84 1647.84 7760.94 C++ Note: derivs checked 1060.93 3775.1 27203.7 C++ Note: second derivs checked 1060.93 11977.1 111988 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 1647.84 7760.94 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 1647.84 7760.94 C++ Note: risk checked 14328.5 C++ Note: risk1 checked 8953.84 33119.7 44341.6 C++ Note: risk2 checked 8953.84 104570 182492 C++ Note: riskr checked 34488.8 C++ Note: risk1r checked 21529.9 80578.6 94839.5 C++ Note: risk2r checked 21529.9 254610 351090 C++ Note: riskl checked 470.725 C++ Note: risk1l checked 299.436 1220.36 1425.98 C++ Note: risk2l checked 299.436 4016.13 5259.82 C++ Note: df101 -117.31 -117.31 -117.31 C++ Note: df102 -0.252504 -0.212118 -1.1189 C++ Note: df103 -6.08937 -50.5934 -9.22555 C++ Note: df104 0.469257 0.102151 0.78977 C++ Note: df105 0.0414663 0.00419259 0.121283 C++ Note: df106 464.589 553.044 104.844 C++ Note: df100 16605 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: riskr checked 34488.8 C++ Note: risk1r checked 21529.9 80578.6 94839.5 C++ Note: risk2r checked 21529.9 254610 351090 C++ Note: riskl checked 470.725 C++ Note: risk1l checked 299.436 1220.36 1425.98 C++ Note: risk2l checked 299.436 4016.13 5259.82 C++ Note: df101 -117.31 -117.31 -117.31 C++ Note: df102 -0.252504 -0.212118 -1.1189 C++ Note: df103 -6.08937 -50.5934 -9.22555 C++ Note: df104 0.469257 0.102151 0.78977 C++ Note: df105 0.0414663 0.00419259 0.121283 C++ Note: df106 464.589 553.044 104.844 C++ Note: riskr checked 34488.8 C++ Note: risk1r checked 21529.9 80578.6 94839.5 C++ Note: risk2r checked 21529.9 254610 351090 C++ Note: riskl checked 470.725 C++ Note: risk1l checked 299.436 1220.36 1425.98 C++ Note: risk2l checked 299.436 4016.13 5259.82 C++ Note: df101 -117.31 -117.31 -117.31 C++ Note: df102 -0.252504 -0.212118 -1.1189 C++ Note: df103 -6.08937 -50.5934 -9.22555 C++ Note: df104 0.469257 0.102151 0.78977 C++ Note: df105 0.0414663 0.00419259 0.121283 C++ Note: df106 464.589 553.044 104.844 C++ Note: Exiting Regression C++ Note: df501 -117.3104 C++ Note: df504 0.4692569 0.1021509 0.7897698 Warning: model covariate order changed Note: 26 risk groups Error: guesses: 50 , iterations per guess: c(1, 1) Warning: model covariate order changed Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: Term checked 0 0 1 C++ Note: df99,30,Starting C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: Grouping Start C++ Note: df100 202 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: starting subterms 2 in guess 0 C++ Note: values checked 0.426096 0.646539 0.157278 C++ Note: sums checked 7274.1 7274.1 1341.83 C++ Note: derivs checked 4601.97 23182.6 2733.27 C++ Note: second derivs checked 4601.97 82544.2 8524.37 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 7274.1 1341.83 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 7274.1 1341.83 C++ Note: risk checked 17001 C++ Note: risk1 checked 10706.4 54122.7 19625.6 C++ Note: risk2 checked 10706.4 192502 61415.9 C++ Note: Made Risk Side Lists C++ Note: riskr checked 45411.7 C++ Note: risk1r checked 28767.4 144720 52387.3 C++ Note: risk2r checked 28767.4 514964 151495 C++ Note: riskl checked 498.666 C++ Note: risk1l checked 304.226 1582.04 793.308 C++ Note: risk2l checked 304.226 5554.38 2609.55 C++ Note: df101 -124.812 -124.812 -124.812 C++ Note: df102 -0.467622 -22.6674 2.97163 C++ Note: df103 -6.02126 -30.6469 -1.27345 C++ Note: df104 0.426096 0.646539 0.157278 C++ Note: df105 0.0776618 0.739632 -2.33354 C++ Note: df106 266.907 5.50621 -42.001 C++ Note: Starting Halves C++ Note: df501 -124.8115 C++ Note: df504 0.4260961 0.646539 0.1572781 C++ Note: values checked 0.600743 0.0965281 1.15728 C++ Note: sums checked 1773.98 1773.98 32135.8 C++ Note: derivs checked 1194.6 4043.19 134742 C++ Note: second derivs checked 1194.6 12805.3 616015 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 1773.98 32135.8 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 1773.98 32135.8 C++ Note: risk checked 58026.5 C++ Note: risk1 checked 37651.2 135360 236019 C++ Note: risk2 checked 37651.2 427814 1.08252e+06 C++ Note: riskr checked 119495 C++ Note: risk1r checked 76635.5 283568 429089 C++ Note: risk2r checked 76635.5 896488 1.77407e+06 C++ Note: riskl checked 1711.94 C++ Note: risk1l checked 1027.65 4618.5 6140.17 C++ Note: risk2l checked 1027.65 15652.6 24115.3 C++ Note: df101 -118.395 -118.395 -118.395 C++ Note: df102 -0.782638 -0.410558 -4.43759 C++ Note: df103 -5.94091 -49.8573 -9.26764 C++ Note: df104 0.600743 0.0965281 1.15728 C++ Note: df105 0.131737 0.00823466 0.478826 C++ Note: df106 151.277 288.376 26.68 C++ Note: df100 2831 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: riskr checked 119495 C++ Note: risk1r checked 76635.5 283568 429089 C++ Note: risk2r checked 76635.5 896488 1.77407e+06 C++ Note: riskl checked 1711.94 C++ Note: risk1l checked 1027.65 4618.5 6140.17 C++ Note: risk2l checked 1027.65 15652.6 24115.3 C++ Note: df101 -118.395 -118.395 -118.395 C++ Note: df102 -0.782638 -0.410558 -4.43759 C++ Note: df103 -5.94091 -49.8573 -9.26764 C++ Note: df104 0.600743 0.0965281 1.15728 C++ Note: df105 0.131737 0.00823466 0.478826 C++ Note: df106 151.277 288.376 26.68 C++ Note: ending guess 0 C++ Note: df501 -118.395 C++ Note: df504 0.6007434 0.09652814 1.157278 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.6007434 0.09652814 1.157278, -118.395<-- Best Guess C++ Note: starting subterms 2 in best guess 0 C++ Note: values checked 0.600743 0.0965281 1.15728 C++ Note: sums checked 1773.98 1773.98 32135.8 C++ Note: derivs checked 1194.6 4043.19 134742 C++ Note: second derivs checked 1194.6 12805.3 616015 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 1773.98 32135.8 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 1773.98 32135.8 C++ Note: risk checked 58026.5 C++ Note: risk1 checked 37651.2 135360 236019 C++ Note: risk2 checked 37651.2 427814 1.08252e+06 C++ Note: Made Risk Side Lists C++ Note: riskr checked 119495 C++ Note: risk1r checked 76635.5 283568 429089 C++ Note: risk2r checked 76635.5 896488 1.77407e+06 C++ Note: riskl checked 1711.94 C++ Note: risk1l checked 1027.65 4618.5 6140.17 C++ Note: risk2l checked 1027.65 15652.6 24115.3 C++ Note: df101 -118.395 -118.395 -118.395 C++ Note: df102 -0.782638 -0.410558 -4.43759 C++ Note: df103 -5.94091 -49.8573 -9.26764 C++ Note: df104 0.600743 0.0965281 1.15728 C++ Note: df105 0.131737 0.00823466 0.478826 C++ Note: df106 151.277 288.376 26.68 C++ Note: Starting Halves C++ Note: df501 -118.395 C++ Note: df504 0.6007434 0.09652814 1.157278 C++ Note: values checked 0.469257 0.102151 0.78977 C++ Note: sums checked 1647.84 1647.84 7760.94 C++ Note: derivs checked 1060.93 3775.1 27203.7 C++ Note: second derivs checked 1060.93 11977.1 111988 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 1647.84 7760.94 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 1647.84 7760.94 C++ Note: risk checked 14328.5 C++ Note: risk1 checked 8953.84 33119.7 44341.6 C++ Note: risk2 checked 8953.84 104570 182492 C++ Note: riskr checked 34488.8 C++ Note: risk1r checked 21529.9 80578.6 94839.5 C++ Note: risk2r checked 21529.9 254610 351090 C++ Note: riskl checked 470.725 C++ Note: risk1l checked 299.436 1220.36 1425.98 C++ Note: risk2l checked 299.436 4016.13 5259.82 C++ Note: df101 -117.31 -117.31 -117.31 C++ Note: df102 -0.252504 -0.212118 -1.1189 C++ Note: df103 -6.08937 -50.5934 -9.22555 C++ Note: df104 0.469257 0.102151 0.78977 C++ Note: df105 0.0414663 0.00419259 0.121283 C++ Note: df106 464.589 553.044 104.844 C++ Note: df100 6105 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: riskr checked 34488.8 C++ Note: risk1r checked 21529.9 80578.6 94839.5 C++ Note: risk2r checked 21529.9 254610 351090 C++ Note: riskl checked 470.725 C++ Note: risk1l checked 299.436 1220.36 1425.98 C++ Note: risk2l checked 299.436 4016.13 5259.82 C++ Note: df101 -117.31 -117.31 -117.31 C++ Note: df102 -0.252504 -0.212118 -1.1189 C++ Note: df103 -6.08937 -50.5934 -9.22555 C++ Note: df104 0.469257 0.102151 0.78977 C++ Note: df105 0.0414663 0.00419259 0.121283 C++ Note: df106 464.589 553.044 104.844 C++ Note: riskr checked 34488.8 C++ Note: risk1r checked 21529.9 80578.6 94839.5 C++ Note: risk2r checked 21529.9 254610 351090 C++ Note: riskl checked 470.725 C++ Note: risk1l checked 299.436 1220.36 1425.98 C++ Note: risk2l checked 299.436 4016.13 5259.82 C++ Note: df101 -117.31 -117.31 -117.31 C++ Note: df102 -0.252504 -0.212118 -1.1189 C++ Note: df103 -6.08937 -50.5934 -9.22555 C++ Note: df104 0.469257 0.102151 0.78977 C++ Note: df105 0.0414663 0.00419259 0.121283 C++ Note: df106 464.589 553.044 104.844 C++ Note: Exiting Regression C++ Note: df501 -117.3104 C++ Note: df504 0.4692569 0.1021509 0.7897698 Warning: model covariate order changed Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: Term checked 0 0 1 C++ Note: df99,30,Starting C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: Grouping Start C++ Note: df100 206 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: starting subterms 2 in guess 0 C++ Note: values checked 0.426096 0.646539 0.157278 C++ Note: sums checked 7274.1 7274.1 1341.83 C++ Note: derivs checked 4601.97 23182.6 2733.27 C++ Note: second derivs checked 4601.97 82544.2 8524.37 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 7274.1 1341.83 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 7274.1 1341.83 C++ Note: risk checked 17001 C++ Note: risk1 checked 10706.4 54122.7 19625.6 C++ Note: risk2 checked 10706.4 192502 61415.9 C++ Note: Made Risk Side Lists C++ Note: riskr checked 45411.7 C++ Note: risk1r checked 28767.4 144720 52387.3 C++ Note: risk2r checked 28767.4 514964 151495 C++ Note: riskl checked 498.666 C++ Note: risk1l checked 304.226 1582.04 793.308 C++ Note: risk2l checked 304.226 5554.38 2609.55 C++ Note: df101 -124.812 -124.812 -124.812 C++ Note: df102 -0.467622 -22.6674 2.97163 C++ Note: df103 -6.02126 -30.6469 -1.27345 C++ Note: df104 0.426096 0.646539 0.157278 C++ Note: df105 0.0776618 0.739632 -2.33354 C++ Note: df106 266.907 5.50621 -42.001 C++ Note: Starting Halves C++ Note: df501 -124.8115 C++ Note: df504 0.4260961 0.646539 0.1572781 C++ Note: values checked 0.600743 0.0965281 1.15728 C++ Note: sums checked 1773.98 1773.98 32135.8 C++ Note: derivs checked 1194.6 4043.19 134742 C++ Note: second derivs checked 1194.6 12805.3 616015 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 1773.98 32135.8 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 1773.98 32135.8 C++ Note: risk checked 58026.5 C++ Note: risk1 checked 37651.2 135360 236019 C++ Note: risk2 checked 37651.2 427814 1.08252e+06 C++ Note: riskr checked 119495 C++ Note: risk1r checked 76635.5 283568 429089 C++ Note: risk2r checked 76635.5 896488 1.77407e+06 C++ Note: riskl checked 1711.94 C++ Note: risk1l checked 1027.65 4618.5 6140.17 C++ Note: risk2l checked 1027.65 15652.6 24115.3 C++ Note: df101 -118.395 -118.395 -118.395 C++ Note: df102 -0.782638 -0.410558 -4.43759 C++ Note: df103 -5.94091 -49.8573 -9.26764 C++ Note: df104 0.600743 0.0965281 1.15728 C++ Note: df105 0.131737 0.00823466 0.478826 C++ Note: df106 151.277 288.376 26.68 C++ Note: df100 2893 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: riskr checked 119495 C++ Note: risk1r checked 76635.5 283568 429089 C++ Note: risk2r checked 76635.5 896488 1.77407e+06 C++ Note: riskl checked 1711.94 C++ Note: risk1l checked 1027.65 4618.5 6140.17 C++ Note: risk2l checked 1027.65 15652.6 24115.3 C++ Note: df101 -118.395 -118.395 -118.395 C++ Note: df102 -0.782638 -0.410558 -4.43759 C++ Note: df103 -5.94091 -49.8573 -9.26764 C++ Note: df104 0.600743 0.0965281 1.15728 C++ Note: df105 0.131737 0.00823466 0.478826 C++ Note: df106 151.277 288.376 26.68 C++ Note: ending guess 0 C++ Note: df501 -118.395 C++ Note: df504 0.6007434 0.09652814 1.157278 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.6007434 0.09652814 1.157278, -118.395<-- Best Guess C++ Note: starting subterms 2 in best guess 0 C++ Note: values checked 0.600743 0.0965281 1.15728 C++ Note: sums checked 1773.98 1773.98 32135.8 C++ Note: derivs checked 1194.6 4043.19 134742 C++ Note: second derivs checked 1194.6 12805.3 616015 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 1773.98 32135.8 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 1773.98 32135.8 C++ Note: risk checked 58026.5 C++ Note: risk1 checked 37651.2 135360 236019 C++ Note: risk2 checked 37651.2 427814 1.08252e+06 C++ Note: Made Risk Side Lists C++ Note: riskr checked 119495 C++ Note: risk1r checked 76635.5 283568 429089 C++ Note: risk2r checked 76635.5 896488 1.77407e+06 C++ Note: riskl checked 1711.94 C++ Note: risk1l checked 1027.65 4618.5 6140.17 C++ Note: risk2l checked 1027.65 15652.6 24115.3 C++ Note: df101 -118.395 -118.395 -118.395 C++ Note: df102 -0.782638 -0.410558 -4.43759 C++ Note: df103 -5.94091 -49.8573 -9.26764 C++ Note: df104 0.600743 0.0965281 1.15728 C++ Note: df105 0.131737 0.00823466 0.478826 C++ Note: df106 151.277 288.376 26.68 C++ Note: Starting Halves C++ Note: df501 -118.395 C++ Note: df504 0.6007434 0.09652814 1.157278 C++ Note: values checked 0.469257 0.102151 0.78977 C++ Note: sums checked 1647.84 1647.84 7760.94 C++ Note: derivs checked 1060.93 3775.1 27203.7 C++ Note: second derivs checked 1060.93 11977.1 111988 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 1647.84 7760.94 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 1647.84 7760.94 C++ Note: risk checked 14328.5 C++ Note: risk1 checked 8953.84 33119.7 44341.6 C++ Note: risk2 checked 8953.84 104570 182492 C++ Note: riskr checked 34488.8 C++ Note: risk1r checked 21529.9 80578.6 94839.5 C++ Note: risk2r checked 21529.9 254610 351090 C++ Note: riskl checked 470.725 C++ Note: risk1l checked 299.436 1220.36 1425.98 C++ Note: risk2l checked 299.436 4016.13 5259.82 C++ Note: df101 -117.31 -117.31 -117.31 C++ Note: df102 -0.252504 -0.212118 -1.1189 C++ Note: df103 -6.08937 -50.5934 -9.22555 C++ Note: df104 0.469257 0.102151 0.78977 C++ Note: df105 0.0414663 0.00419259 0.121283 C++ Note: df106 464.589 553.044 104.844 C++ Note: df100 6173 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: riskr checked 34488.8 C++ Note: risk1r checked 21529.9 80578.6 94839.5 C++ Note: risk2r checked 21529.9 254610 351090 C++ Note: riskl checked 470.725 C++ Note: risk1l checked 299.436 1220.36 1425.98 C++ Note: risk2l checked 299.436 4016.13 5259.82 C++ Note: df101 -117.31 -117.31 -117.31 C++ Note: df102 -0.252504 -0.212118 -1.1189 C++ Note: df103 -6.08937 -50.5934 -9.22555 C++ Note: df104 0.469257 0.102151 0.78977 C++ Note: df105 0.0414663 0.00419259 0.121283 C++ Note: df106 464.589 553.044 104.844 C++ Note: riskr checked 34488.8 C++ Note: risk1r checked 21529.9 80578.6 94839.5 C++ Note: risk2r checked 21529.9 254610 351090 C++ Note: riskl checked 470.725 C++ Note: risk1l checked 299.436 1220.36 1425.98 C++ Note: risk2l checked 299.436 4016.13 5259.82 C++ Note: df101 -117.31 -117.31 -117.31 C++ Note: df102 -0.252504 -0.212118 -1.1189 C++ Note: df103 -6.08937 -50.5934 -9.22555 C++ Note: df104 0.469257 0.102151 0.78977 C++ Note: df105 0.0414663 0.00419259 0.121283 C++ Note: df106 464.589 553.044 104.844 C++ Note: Exiting Regression C++ Note: df501 -117.3104 C++ Note: df504 0.4692569 0.1021509 0.7897698 Warning: model covariate order changed Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: Term checked 0 0 1 C++ Note: df99,30,Starting C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: Grouping Start C++ Note: df100 209 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: starting subterms 2 in guess 0 C++ Note: values checked -0.1 -0.1 0.2 C++ Note: sums checked -261.4 -261.4 341.682 C++ Note: derivs checked 531 2083 1708.41 C++ Note: second derivs checked 0 0 0 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked -261.4 341.682 C++ Note: LIN_non-dose checked -261.4 341.682 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 1000 1000 C++ Error: A non-positive risk was detected: -1.111148 C++ Warning: final failing values -0.1 -0.1 0.2 Invalid risk Warning: model covariate order changed C++ Note: START_POIS_GUESS C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: Term checked 0 0 1 C++ Note: df99,30,Starting C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: starting subterms 2 in guess 0 C++ Note: values checked 0.426096 0.646539 0.157278 C++ Note: sums checked 7274.1 7274.1 1341.83 C++ Note: derivs checked 4601.97 23182.6 2733.27 C++ Note: second derivs checked 4601.97 82544.2 8524.37 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 7274.1 1341.83 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 7274.1 1341.83 C++ Note: risk checked 17001 C++ Note: risk1 checked 10706.4 54122.7 19625.6 C++ Note: risk2 checked 10706.4 192502 61415.9 C++ Note: df101 -18942.2 -18942.2 -18942.2 C++ Note: df102 -12053.5 -60927.3 -21843.1 C++ Note: df103 -12141.5 -218114 -69007.6 C++ Note: df104 0.426096 0.646539 0.157278 C++ Note: Checking Deviance 37742.9 C++ Note: df105 0.992752 0.279337 0.316532 C++ Note: df106 1.57151 0.310899 0.867193 C++ Note: Starting Halves C++ Note: df501 -18942.23 C++ Note: df504 0.4260961 0.646539 0.1572781 C++ Note: values checked 0.254195 0.478304 0.123322 C++ Note: sums checked 3900.36 3900.36 1253.74 C++ Note: derivs checked 2309.18 11554.8 2460.98 C++ Note: second derivs checked 2309.18 40015.3 7535.66 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 3900.36 1253.74 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 3900.36 1253.74 C++ Note: risk checked 8783.44 C++ Note: risk1 checked 5182.78 26003.4 9537.67 C++ Note: risk2 checked 5182.78 89978.1 29321.3 C++ Note: df101 -9722.07 -9722.07 -9722.07 C++ Note: df102 -5791.51 -29075 -10520.7 C++ Note: df103 -5879.51 -101991 -32827.7 C++ Note: df104 0.254195 0.478304 0.123322 C++ Note: Checking Deviance 19302.5 C++ Note: df105 0.985033 0.285074 0.320482 C++ Note: df106 1.67868 0.334379 0.924092 C++ Note: df100 2072 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: df100 2120 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: df101 -9722.072 -9722.072 -9722.072 C++ Note: df102 -5791.513 -29075.02 -10520.68 C++ Note: df103 -5879.513 -101991.2 -32827.7 C++ Note: df104 0.2541947 0.4783037 0.1233221 C++ Note: Checking Deviance 19302.54 C++ Note: df105 0.9850328 0.2850738 0.3204818 C++ Note: df106 1.678676 0.3343789 0.9240916 C++ Note: df101 -9722.07 -9722.07 -9722.07 C++ Note: df102 -5791.51 -29075 -10520.7 C++ Note: df103 -5879.51 -101991 -32827.7 C++ Note: df104 0.254195 0.478304 0.123322 C++ Note: Checking Deviance 19302.5 C++ Note: df105 0.985033 0.285074 0.320482 C++ Note: df106 1.67868 0.334379 0.924092 C++ Note: ending guess 0 C++ Note: df501 -9722.072 C++ Note: df504 0.2541947 0.4783037 0.1233221 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.2541947 0.4783037 0.1233221, -9722.072<-- Best Guess C++ Note: starting subterms 2 in best guess 0 C++ Note: values checked 0.254195 0.478304 0.123322 C++ Note: sums checked 3900.36 3900.36 1253.74 C++ Note: derivs checked 2309.18 11554.8 2460.98 C++ Note: second derivs checked 2309.18 40015.3 7535.66 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 3900.36 1253.74 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 3900.36 1253.74 C++ Note: risk checked 8783.44 C++ Note: risk1 checked 5182.78 26003.4 9537.67 C++ Note: risk2 checked 5182.78 89978.1 29321.3 C++ Note: Made Risk Side Lists C++ Note: df101 -9722.07 -9722.07 -9722.07 C++ Note: df102 -5791.51 -29075 -10520.7 C++ Note: df103 -5879.51 -101991 -32827.7 C++ Note: df104 0.254195 0.478304 0.123322 C++ Note: Checking Deviance 19302.5 C++ Note: df105 0.985033 0.285074 0.320482 C++ Note: df106 1.67868 0.334379 0.924092 C++ Note: Starting Halves C++ Note: df501 -9722.072 C++ Note: df504 0.2541947 0.4783037 0.1233221 C++ Note: values checked 0.0500616 0.312566 0.0802485 C++ Note: sums checked 2172.57 2172.57 1154.38 C++ Note: derivs checked 1178.37 5851.84 2160.22 C++ Note: second derivs checked 1178.37 19594.1 6459.87 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 2172.57 1154.38 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 2172.57 1154.38 C++ Note: risk checked 4679.98 C++ Note: risk1 checked 2533.3 12602.3 4687.51 C++ Note: risk2 checked 2533.3 42177.5 14076.6 C++ Note: df101 -5164.53 -5164.53 -5164.53 C++ Note: df102 -2787.43 -13890.9 -5084.88 C++ Note: df103 -2875.43 -47831.4 -15650.9 C++ Note: df104 0.0500616 0.312566 0.0802485 C++ Note: Checking Deviance 10187.5 C++ Note: df105 0.969396 0.290413 0.324893 C++ Note: df106 1.85279 0.371793 1.01567 C++ Note: df100 4657 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: df100 4706 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:16 2024 C++ Note: df101 -5164.534 -5164.534 -5164.534 C++ Note: df102 -2787.432 -13890.89 -5084.875 C++ Note: df103 -2875.432 -47831.43 -15650.91 C++ Note: df104 0.05006156 0.3125659 0.0802485 C++ Note: Checking Deviance 10187.47 C++ Note: df105 0.9693959 0.2904134 0.3248932 C++ Note: df106 1.852793 0.371793 1.015666 C++ Note: df101 -5164.53 -5164.53 -5164.53 C++ Note: df102 -2787.43 -13890.9 -5084.88 C++ Note: df103 -2875.43 -47831.4 -15650.9 C++ Note: df104 0.0500616 0.312566 0.0802485 C++ Note: Checking Deviance 10187.5 C++ Note: df105 0.969396 0.290413 0.324893 C++ Note: df106 1.85279 0.371793 1.01567 C++ Note: df501 -5164.534 C++ Note: df504 0.05006156 0.3125659 0.0802485 Error: Atleast one parameter must be free Warning: model covariate order changed Error: no events Warning: model covariate order changed Note: Initial starts: 1 , Number of iterations provided: 4 . Colossus requires one more iteration counts than number of guesses (for best guess) C++ Note: START_POIS_GUESS C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 1 C++ Note: df99,30,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 2 in guess 0 C++ Note: values checked 0.426096 0.646539 0.157278 C++ Note: sums checked 7274.1 7274.1 1341.83 C++ Note: derivs checked 4601.97 23182.6 2733.27 C++ Note: second derivs checked 4601.97 82544.2 8524.37 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 7274.1 1341.83 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 7274.1 1341.83 C++ Note: risk checked 17001 C++ Note: risk1 checked 10706.4 54122.7 19625.6 C++ Note: risk2 checked 10706.4 192502 61415.9 C++ Note: df101 -18942.2 -18942.2 -18942.2 C++ Note: df102 -12053.5 -60927.3 -21843.1 C++ Note: df103 -12141.5 -218114 -69007.6 C++ Note: df104 0.426096 0.646539 0.157278 C++ Note: Checking Deviance 37742.9 C++ Note: df105 0.992752 0.279337 0.316532 C++ Note: df106 1.57151 0.310899 0.867193 C++ Note: Starting Halves C++ Note: df501 -18942.23 C++ Note: df504 0.4260961 0.646539 0.1572781 C++ Note: values checked 0.254195 0.478304 0.123322 C++ Note: sums checked 3900.36 3900.36 1253.74 C++ Note: derivs checked 2309.18 11554.8 2460.98 C++ Note: second derivs checked 2309.18 40015.3 7535.66 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 3900.36 1253.74 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 3900.36 1253.74 C++ Note: risk checked 8783.44 C++ Note: risk1 checked 5182.78 26003.4 9537.67 C++ Note: risk2 checked 5182.78 89978.1 29321.3 C++ Note: df101 -9722.07 -9722.07 -9722.07 C++ Note: df102 -5791.51 -29075 -10520.7 C++ Note: df103 -5879.51 -101991 -32827.7 C++ Note: df104 0.254195 0.478304 0.123322 C++ Note: Checking Deviance 19302.5 C++ Note: df105 0.985033 0.285074 0.320482 C++ Note: df106 1.67868 0.334379 0.924092 C++ Note: df100 2074 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: df100 2122 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: df101 -9722.072 -9722.072 -9722.072 C++ Note: df102 -5791.513 -29075.02 -10520.68 C++ Note: df103 -5879.513 -101991.2 -32827.7 C++ Note: df104 0.2541947 0.4783037 0.1233221 C++ Note: Checking Deviance 19302.54 C++ Note: df105 0.9850328 0.2850738 0.3204818 C++ Note: df106 1.678676 0.3343789 0.9240916 C++ Note: df101 -9722.07 -9722.07 -9722.07 C++ Note: df102 -5791.51 -29075 -10520.7 C++ Note: df103 -5879.51 -101991 -32827.7 C++ Note: df104 0.254195 0.478304 0.123322 C++ Note: Checking Deviance 19302.5 C++ Note: df105 0.985033 0.285074 0.320482 C++ Note: df106 1.67868 0.334379 0.924092 C++ Note: ending guess 0 C++ Note: df501 -9722.072 C++ Note: df504 0.2541947 0.4783037 0.1233221 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.2541947 0.4783037 0.1233221, -9722.072<-- Best Guess C++ Note: starting subterms 2 in best guess 0 C++ Note: values checked 0.254195 0.478304 0.123322 C++ Note: sums checked 3900.36 3900.36 1253.74 C++ Note: derivs checked 2309.18 11554.8 2460.98 C++ Note: second derivs checked 2309.18 40015.3 7535.66 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 3900.36 1253.74 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 3900.36 1253.74 C++ Note: risk checked 8783.44 C++ Note: risk1 checked 5182.78 26003.4 9537.67 C++ Note: risk2 checked 5182.78 89978.1 29321.3 C++ Note: Made Risk Side Lists C++ Note: df101 -9722.07 -9722.07 -9722.07 C++ Note: df102 -5791.51 -29075 -10520.7 C++ Note: df103 -5879.51 -101991 -32827.7 C++ Note: df104 0.254195 0.478304 0.123322 C++ Note: Checking Deviance 19302.5 C++ Note: df105 0.985033 0.285074 0.320482 C++ Note: df106 1.67868 0.334379 0.924092 C++ Note: Starting Halves C++ Note: df501 -9722.072 C++ Note: df504 0.2541947 0.4783037 0.1233221 C++ Note: values checked 0.0500616 0.312566 0.0802485 C++ Note: sums checked 2172.57 2172.57 1154.38 C++ Note: derivs checked 1178.37 5851.84 2160.22 C++ Note: second derivs checked 1178.37 19594.1 6459.87 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 2172.57 1154.38 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 2172.57 1154.38 C++ Note: risk checked 4679.98 C++ Note: risk1 checked 2533.3 12602.3 4687.51 C++ Note: risk2 checked 2533.3 42177.5 14076.6 C++ Note: df101 -5164.53 -5164.53 -5164.53 C++ Note: df102 -2787.43 -13890.9 -5084.88 C++ Note: df103 -2875.43 -47831.4 -15650.9 C++ Note: df104 0.0500616 0.312566 0.0802485 C++ Note: Checking Deviance 10187.5 C++ Note: df105 0.969396 0.290413 0.324893 C++ Note: df106 1.85279 0.371793 1.01567 C++ Note: df100 4674 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: df100 4722 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: df101 -5164.534 -5164.534 -5164.534 C++ Note: df102 -2787.432 -13890.89 -5084.875 C++ Note: df103 -2875.432 -47831.43 -15650.91 C++ Note: df104 0.05006156 0.3125659 0.0802485 C++ Note: Checking Deviance 10187.47 C++ Note: df105 0.9693959 0.2904134 0.3248932 C++ Note: df106 1.852793 0.371793 1.015666 C++ Note: df101 -5164.53 -5164.53 -5164.53 C++ Note: df102 -2787.43 -13890.9 -5084.88 C++ Note: df103 -2875.43 -47831.4 -15650.9 C++ Note: df104 0.0500616 0.312566 0.0802485 C++ Note: Checking Deviance 10187.5 C++ Note: df105 0.969396 0.290413 0.324893 C++ Note: df106 1.85279 0.371793 1.01567 C++ Note: df501 -5164.534 C++ Note: df504 0.05006156 0.3125659 0.0802485 Warning: model covariate order changed Note: Initial starts: 3 , Number of iterations provided: 2 . Colossus requires one more iteration counts than number of guesses (for best guess) C++ Note: START_POIS_GUESS C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 1 C++ Note: df99,30,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 2 in guess 0 C++ Note: values checked 0.426096 0.646539 0.157278 C++ Note: sums checked 7274.1 7274.1 1341.83 C++ Note: derivs checked 4601.97 23182.6 2733.27 C++ Note: second derivs checked 4601.97 82544.2 8524.37 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 7274.1 1341.83 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 7274.1 1341.83 C++ Note: risk checked 17001 C++ Note: risk1 checked 10706.4 54122.7 19625.6 C++ Note: risk2 checked 10706.4 192502 61415.9 C++ Note: df101 -18942.2 -18942.2 -18942.2 C++ Note: df102 -12053.5 -60927.3 -21843.1 C++ Note: df103 -12141.5 -218114 -69007.6 C++ Note: df104 0.426096 0.646539 0.157278 C++ Note: Checking Deviance 37742.9 C++ Note: df105 0.992752 0.279337 0.316532 C++ Note: df106 1.57151 0.310899 0.867193 C++ Note: Starting Halves C++ Note: df501 -18942.23 C++ Note: df504 0.4260961 0.646539 0.1572781 C++ Note: values checked 0.254195 0.478304 0.123322 C++ Note: sums checked 3900.36 3900.36 1253.74 C++ Note: derivs checked 2309.18 11554.8 2460.98 C++ Note: second derivs checked 2309.18 40015.3 7535.66 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 3900.36 1253.74 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 3900.36 1253.74 C++ Note: risk checked 8783.44 C++ Note: risk1 checked 5182.78 26003.4 9537.67 C++ Note: risk2 checked 5182.78 89978.1 29321.3 C++ Note: df101 -9722.07 -9722.07 -9722.07 C++ Note: df102 -5791.51 -29075 -10520.7 C++ Note: df103 -5879.51 -101991 -32827.7 C++ Note: df104 0.254195 0.478304 0.123322 C++ Note: Checking Deviance 19302.5 C++ Note: df105 0.985033 0.285074 0.320482 C++ Note: df106 1.67868 0.334379 0.924092 C++ Note: df100 2052 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: df100 2101 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: df101 -9722.072 -9722.072 -9722.072 C++ Note: df102 -5791.513 -29075.02 -10520.68 C++ Note: df103 -5879.513 -101991.2 -32827.7 C++ Note: df104 0.2541947 0.4783037 0.1233221 C++ Note: Checking Deviance 19302.54 C++ Note: df105 0.9850328 0.2850738 0.3204818 C++ Note: df106 1.678676 0.3343789 0.9240916 C++ Note: df101 -9722.07 -9722.07 -9722.07 C++ Note: df102 -5791.51 -29075 -10520.7 C++ Note: df103 -5879.51 -101991 -32827.7 C++ Note: df104 0.254195 0.478304 0.123322 C++ Note: Checking Deviance 19302.5 C++ Note: df105 0.985033 0.285074 0.320482 C++ Note: df106 1.67868 0.334379 0.924092 C++ Note: ending guess 0 C++ Note: df501 -9722.072 C++ Note: df504 0.2541947 0.4783037 0.1233221 C++ Note: starting subterms 2 in guess 1 C++ Note: values checked 0.426096 0.646539 0.157278 C++ Note: sums checked 7274.1 7274.1 1341.83 C++ Note: derivs checked 4601.97 23182.6 2733.27 C++ Note: second derivs checked 4601.97 82544.2 8524.37 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 7274.1 1341.83 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 7274.1 1341.83 C++ Note: risk checked 17001 C++ Note: risk1 checked 10706.4 54122.7 19625.6 C++ Note: risk2 checked 10706.4 192502 61415.9 C++ Note: df101 -18942.2 -18942.2 -18942.2 C++ Note: df102 -12053.5 -60927.3 -21843.1 C++ Note: df103 -12141.5 -218114 -69007.6 C++ Note: df104 0.426096 0.646539 0.157278 C++ Note: Checking Deviance 37742.9 C++ Note: df105 0.992752 0.279337 0.316532 C++ Note: df106 1.57151 0.310899 0.867193 C++ Note: Starting Halves C++ Note: df501 -9722.072 C++ Note: df504 0.2541947 0.4783037 0.1233221 C++ Note: values checked 0.254195 0.478304 0.123322 C++ Note: sums checked 3900.36 3900.36 1253.74 C++ Note: derivs checked 2309.18 11554.8 2460.98 C++ Note: second derivs checked 2309.18 40015.3 7535.66 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 3900.36 1253.74 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 3900.36 1253.74 C++ Note: risk checked 8783.44 C++ Note: risk1 checked 5182.78 26003.4 9537.67 C++ Note: risk2 checked 5182.78 89978.1 29321.3 C++ Note: df101 -9722.07 -9722.07 -9722.07 C++ Note: df102 -5791.51 -29075 -10520.7 C++ Note: df103 -5879.51 -101991 -32827.7 C++ Note: df104 0.254195 0.478304 0.123322 C++ Note: Checking Deviance 19302.5 C++ Note: df105 0.985033 0.285074 0.320482 C++ Note: df106 1.67868 0.334379 0.924092 C++ Note: df100 4570 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: values checked 0.340145 0.562421 0.1403 C++ Note: sums checked 5296.79 5296.79 1296.63 C++ Note: derivs checked 3244.35 16318.8 2592.93 C++ Note: second derivs checked 3244.35 57346.2 8013.16 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 5296.79 1296.63 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 5296.79 1296.63 C++ Note: risk checked 12148.9 C++ Note: risk1 checked 7411.88 37396.1 13604.8 C++ Note: risk2 checked 7411.88 131289 42203 C++ Note: df101 -13490.5 -13490.5 -13490.5 C++ Note: df102 -8318.73 -41981.5 -15084.1 C++ Note: df103 -8406.73 -148787 -47345.2 C++ Note: df104 0.340145 0.562421 0.1403 C++ Note: Checking Deviance 26839.3 C++ Note: df105 0.989532 0.282158 0.318597 C++ Note: df106 1.6217 0.321343 0.894353 C++ Note: df100 5540 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Changing back to best C++ Note: values checked 0.426096 0.646539 0.157278 C++ Note: sums checked 7274.1 7274.1 1341.83 C++ Note: derivs checked 4601.97 23182.6 2733.27 C++ Note: second derivs checked 4601.97 82544.2 8524.37 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 7274.1 1341.83 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 7274.1 1341.83 C++ Note: risk checked 17001 C++ Note: risk1 checked 10706.4 54122.7 19625.6 C++ Note: risk2 checked 10706.4 192502 61415.9 C++ Note: df101 -18942.2 -18942.2 -18942.2 C++ Note: df102 -12053.5 -60927.3 -21843.1 C++ Note: df103 -12141.5 -218114 -69007.6 C++ Note: df104 0.426096 0.646539 0.157278 C++ Note: Checking Deviance 37742.9 C++ Note: df105 0.992752 0.279337 0.316532 C++ Note: df106 1.57151 0.310899 0.867193 C++ Note: df100 6494 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: df101 -18942.23 -18942.23 -18942.23 C++ Note: df102 -12053.55 -60927.32 -21843.14 C++ Note: df103 -12141.55 -218114.1 -69007.65 C++ Note: df104 0.4260961 0.646539 0.1572781 C++ Note: Checking Deviance 37742.86 C++ Note: df105 0.9927522 0.2793369 0.3165322 C++ Note: df106 1.571507 0.3108988 0.8671935 C++ Note: df101 -18942.2 -18942.2 -18942.2 C++ Note: df102 -12053.5 -60927.3 -21843.1 C++ Note: df103 -12141.5 -218114 -69007.6 C++ Note: df104 0.426096 0.646539 0.157278 C++ Note: Checking Deviance 37742.9 C++ Note: df105 0.992752 0.279337 0.316532 C++ Note: df106 1.57151 0.310899 0.867193 C++ Note: ending guess 1 C++ Note: df501 -9722.072 C++ Note: df504 0.2541947 0.4783037 0.1233221 C++ Note: starting subterms 2 in guess 2 C++ Note: values checked 0.426096 0.646539 0.157278 C++ Note: sums checked 7274.1 7274.1 1341.83 C++ Note: derivs checked 4601.97 23182.6 2733.27 C++ Note: second derivs checked 4601.97 82544.2 8524.37 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 7274.1 1341.83 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 7274.1 1341.83 C++ Note: risk checked 17001 C++ Note: risk1 checked 10706.4 54122.7 19625.6 C++ Note: risk2 checked 10706.4 192502 61415.9 C++ Note: df101 -18942.2 -18942.2 -18942.2 C++ Note: df102 -12053.5 -60927.3 -21843.1 C++ Note: df103 -12141.5 -218114 -69007.6 C++ Note: df104 0.426096 0.646539 0.157278 C++ Note: Checking Deviance 37742.9 C++ Note: df105 0.992752 0.279337 0.316532 C++ Note: df106 1.57151 0.310899 0.867193 C++ Note: Starting Halves C++ Note: df501 -9722.072 C++ Note: df504 0.2541947 0.4783037 0.1233221 C++ Note: values checked 0.254195 0.478304 0.123322 C++ Note: sums checked 3900.36 3900.36 1253.74 C++ Note: derivs checked 2309.18 11554.8 2460.98 C++ Note: second derivs checked 2309.18 40015.3 7535.66 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 3900.36 1253.74 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 3900.36 1253.74 C++ Note: risk checked 8783.44 C++ Note: risk1 checked 5182.78 26003.4 9537.67 C++ Note: risk2 checked 5182.78 89978.1 29321.3 C++ Note: df101 -9722.07 -9722.07 -9722.07 C++ Note: df102 -5791.51 -29075 -10520.7 C++ Note: df103 -5879.51 -101991 -32827.7 C++ Note: df104 0.254195 0.478304 0.123322 C++ Note: Checking Deviance 19302.5 C++ Note: df105 0.985033 0.285074 0.320482 C++ Note: df106 1.67868 0.334379 0.924092 C++ Note: df100 8996 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: values checked 0.340145 0.562421 0.1403 C++ Note: sums checked 5296.79 5296.79 1296.63 C++ Note: derivs checked 3244.35 16318.8 2592.93 C++ Note: second derivs checked 3244.35 57346.2 8013.16 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 5296.79 1296.63 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 5296.79 1296.63 C++ Note: risk checked 12148.9 C++ Note: risk1 checked 7411.88 37396.1 13604.8 C++ Note: risk2 checked 7411.88 131289 42203 C++ Note: df101 -13490.5 -13490.5 -13490.5 C++ Note: df102 -8318.73 -41981.5 -15084.1 C++ Note: df103 -8406.73 -148787 -47345.2 C++ Note: df104 0.340145 0.562421 0.1403 C++ Note: Checking Deviance 26839.3 C++ Note: df105 0.989532 0.282158 0.318597 C++ Note: df106 1.6217 0.321343 0.894353 C++ Note: df100 9962 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Changing back to best C++ Note: values checked 0.426096 0.646539 0.157278 C++ Note: sums checked 7274.1 7274.1 1341.83 C++ Note: derivs checked 4601.97 23182.6 2733.27 C++ Note: second derivs checked 4601.97 82544.2 8524.37 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 7274.1 1341.83 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 7274.1 1341.83 C++ Note: risk checked 17001 C++ Note: risk1 checked 10706.4 54122.7 19625.6 C++ Note: risk2 checked 10706.4 192502 61415.9 C++ Note: df101 -18942.2 -18942.2 -18942.2 C++ Note: df102 -12053.5 -60927.3 -21843.1 C++ Note: df103 -12141.5 -218114 -69007.6 C++ Note: df104 0.426096 0.646539 0.157278 C++ Note: Checking Deviance 37742.9 C++ Note: df105 0.992752 0.279337 0.316532 C++ Note: df106 1.57151 0.310899 0.867193 C++ Note: df100 10916 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: df101 -18942.23 -18942.23 -18942.23 C++ Note: df102 -12053.55 -60927.32 -21843.14 C++ Note: df103 -12141.55 -218114.1 -69007.65 C++ Note: df104 0.4260961 0.646539 0.1572781 C++ Note: Checking Deviance 37742.86 C++ Note: df105 0.9927522 0.2793369 0.3165322 C++ Note: df106 1.571507 0.3108988 0.8671935 C++ Note: df101 -18942.2 -18942.2 -18942.2 C++ Note: df102 -12053.5 -60927.3 -21843.1 C++ Note: df103 -12141.5 -218114 -69007.6 C++ Note: df104 0.426096 0.646539 0.157278 C++ Note: Checking Deviance 37742.9 C++ Note: df105 0.992752 0.279337 0.316532 C++ Note: df106 1.57151 0.310899 0.867193 C++ Note: ending guess 2 C++ Note: df501 -9722.072 C++ Note: df504 0.2541947 0.4783037 0.1233221 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.2541947 0.4783037 0.1233221, -9722.072<-- Best Guess 1, 0.4260961 0.646539 0.1572781, -18942.23 2, 0.4260961 0.646539 0.1572781, -18942.23 C++ Note: starting subterms 2 in best guess 0 C++ Note: values checked 0.254195 0.478304 0.123322 C++ Note: sums checked 3900.36 3900.36 1253.74 C++ Note: derivs checked 2309.18 11554.8 2460.98 C++ Note: second derivs checked 2309.18 40015.3 7535.66 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 3900.36 1253.74 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 3900.36 1253.74 C++ Note: risk checked 8783.44 C++ Note: risk1 checked 5182.78 26003.4 9537.67 C++ Note: risk2 checked 5182.78 89978.1 29321.3 C++ Note: Made Risk Side Lists C++ Note: df101 -9722.07 -9722.07 -9722.07 C++ Note: df102 -5791.51 -29075 -10520.7 C++ Note: df103 -5879.51 -101991 -32827.7 C++ Note: df104 0.254195 0.478304 0.123322 C++ Note: Checking Deviance 19302.5 C++ Note: df105 0.985033 0.285074 0.320482 C++ Note: df106 1.67868 0.334379 0.924092 C++ Note: Starting Halves C++ Note: df501 -9722.072 C++ Note: df504 0.2541947 0.4783037 0.1233221 C++ Note: values checked 0.0500616 0.312566 0.0802485 C++ Note: sums checked 2172.57 2172.57 1154.38 C++ Note: derivs checked 1178.37 5851.84 2160.22 C++ Note: second derivs checked 1178.37 19594.1 6459.87 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 2172.57 1154.38 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 2172.57 1154.38 C++ Note: risk checked 4679.98 C++ Note: risk1 checked 2533.3 12602.3 4687.51 C++ Note: risk2 checked 2533.3 42177.5 14076.6 C++ Note: df101 -5164.53 -5164.53 -5164.53 C++ Note: df102 -2787.43 -13890.9 -5084.88 C++ Note: df103 -2875.43 -47831.4 -15650.9 C++ Note: df104 0.0500616 0.312566 0.0802485 C++ Note: Checking Deviance 10187.5 C++ Note: df105 0.969396 0.290413 0.324893 C++ Note: df106 1.85279 0.371793 1.01567 C++ Note: df100 13491 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: df100 13538 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: df101 -5164.534 -5164.534 -5164.534 C++ Note: df102 -2787.432 -13890.89 -5084.875 C++ Note: df103 -2875.432 -47831.43 -15650.91 C++ Note: df104 0.05006156 0.3125659 0.0802485 C++ Note: Checking Deviance 10187.47 C++ Note: df105 0.9693959 0.2904134 0.3248932 C++ Note: df106 1.852793 0.371793 1.015666 C++ Note: df101 -5164.53 -5164.53 -5164.53 C++ Note: df102 -2787.43 -13890.9 -5084.88 C++ Note: df103 -2875.43 -47831.4 -15650.9 C++ Note: df104 0.0500616 0.312566 0.0802485 C++ Note: Checking Deviance 10187.5 C++ Note: df105 0.969396 0.290413 0.324893 C++ Note: df106 1.85279 0.371793 1.01567 C++ Note: df501 -5164.534 C++ Note: df504 0.05006156 0.3125659 0.0802485 Warning: model covariate order changed Error: guesses: 50 , iterations per guess: c(1, 1) Warning: model covariate order changed C++ Note: START_POIS_GUESS C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 1 C++ Note: df99,29,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 2 in guess 0 C++ Note: values checked 0.426096 0.646539 0.157278 C++ Note: sums checked 7274.1 7274.1 1341.83 C++ Note: derivs checked 4601.97 23182.6 2733.27 C++ Note: second derivs checked 4601.97 82544.2 8524.37 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 7274.1 1341.83 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 7274.1 1341.83 C++ Note: risk checked 17001 C++ Note: risk1 checked 10706.4 54122.7 19625.6 C++ Note: risk2 checked 10706.4 192502 61415.9 C++ Note: df101 -18942.2 -18942.2 -18942.2 C++ Note: df102 -12053.5 -60927.3 -21843.1 C++ Note: df103 -12141.5 -218114 -69007.6 C++ Note: df104 0.426096 0.646539 0.157278 C++ Note: Checking Deviance 37742.9 C++ Note: df105 0.992752 0.279337 0.316532 C++ Note: df106 1.57151 0.310899 0.867193 C++ Note: Starting Halves C++ Note: df501 -18942.23 C++ Note: df504 0.4260961 0.646539 0.1572781 C++ Note: values checked 0.254195 0.478304 0.123322 C++ Note: sums checked 3900.36 3900.36 1253.74 C++ Note: derivs checked 2309.18 11554.8 2460.98 C++ Note: second derivs checked 2309.18 40015.3 7535.66 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 3900.36 1253.74 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 3900.36 1253.74 C++ Note: risk checked 8783.44 C++ Note: risk1 checked 5182.78 26003.4 9537.67 C++ Note: risk2 checked 5182.78 89978.1 29321.3 C++ Note: df101 -9722.07 -9722.07 -9722.07 C++ Note: df102 -5791.51 -29075 -10520.7 C++ Note: df103 -5879.51 -101991 -32827.7 C++ Note: df104 0.254195 0.478304 0.123322 C++ Note: Checking Deviance 19302.5 C++ Note: df105 0.985033 0.285074 0.320482 C++ Note: df106 1.67868 0.334379 0.924092 C++ Note: df100 2063 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: df100 2111 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: df101 -9722.072 -9722.072 -9722.072 C++ Note: df102 -5791.513 -29075.02 -10520.68 C++ Note: df103 -5879.513 -101991.2 -32827.7 C++ Note: df104 0.2541947 0.4783037 0.1233221 C++ Note: Checking Deviance 19302.54 C++ Note: df105 0.9850328 0.2850738 0.3204818 C++ Note: df106 1.678676 0.3343789 0.9240916 C++ Note: df101 -9722.07 -9722.07 -9722.07 C++ Note: df102 -5791.51 -29075 -10520.7 C++ Note: df103 -5879.51 -101991 -32827.7 C++ Note: df104 0.254195 0.478304 0.123322 C++ Note: Checking Deviance 19302.5 C++ Note: df105 0.985033 0.285074 0.320482 C++ Note: df106 1.67868 0.334379 0.924092 C++ Note: ending guess 0 C++ Note: df501 -9722.072 C++ Note: df504 0.2541947 0.4783037 0.1233221 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.2541947 0.4783037 0.1233221, -9722.072<-- Best Guess C++ Note: starting subterms 2 in best guess 0 C++ Note: values checked 0.254195 0.478304 0.123322 C++ Note: sums checked 3900.36 3900.36 1253.74 C++ Note: derivs checked 2309.18 11554.8 2460.98 C++ Note: second derivs checked 2309.18 40015.3 7535.66 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 3900.36 1253.74 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 3900.36 1253.74 C++ Note: risk checked 8783.44 C++ Note: risk1 checked 5182.78 26003.4 9537.67 C++ Note: risk2 checked 5182.78 89978.1 29321.3 C++ Note: Made Risk Side Lists C++ Note: df101 -9722.07 -9722.07 -9722.07 C++ Note: df102 -5791.51 -29075 -10520.7 C++ Note: df103 -5879.51 -101991 -32827.7 C++ Note: df104 0.254195 0.478304 0.123322 C++ Note: Checking Deviance 19302.5 C++ Note: df105 0.985033 0.285074 0.320482 C++ Note: df106 1.67868 0.334379 0.924092 C++ Note: Starting Halves C++ Note: df501 -9722.072 C++ Note: df504 0.2541947 0.4783037 0.1233221 C++ Note: values checked 0.0500616 0.312566 0.0802485 C++ Note: sums checked 2172.57 2172.57 1154.38 C++ Note: derivs checked 1178.37 5851.84 2160.22 C++ Note: second derivs checked 1178.37 19594.1 6459.87 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 2172.57 1154.38 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 2172.57 1154.38 C++ Note: risk checked 4679.98 C++ Note: risk1 checked 2533.3 12602.3 4687.51 C++ Note: risk2 checked 2533.3 42177.5 14076.6 C++ Note: df101 -5164.53 -5164.53 -5164.53 C++ Note: df102 -2787.43 -13890.9 -5084.88 C++ Note: df103 -2875.43 -47831.4 -15650.9 C++ Note: df104 0.0500616 0.312566 0.0802485 C++ Note: Checking Deviance 10187.5 C++ Note: df105 0.969396 0.290413 0.324893 C++ Note: df106 1.85279 0.371793 1.01567 C++ Note: df100 4638 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: df100 4686 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: df101 -5164.534 -5164.534 -5164.534 C++ Note: df102 -2787.432 -13890.89 -5084.875 C++ Note: df103 -2875.432 -47831.43 -15650.91 C++ Note: df104 0.05006156 0.3125659 0.0802485 C++ Note: Checking Deviance 10187.47 C++ Note: df105 0.9693959 0.2904134 0.3248932 C++ Note: df106 1.852793 0.371793 1.015666 C++ Note: df101 -5164.53 -5164.53 -5164.53 C++ Note: df102 -2787.43 -13890.9 -5084.88 C++ Note: df103 -2875.43 -47831.4 -15650.9 C++ Note: df104 0.0500616 0.312566 0.0802485 C++ Note: Checking Deviance 10187.5 C++ Note: df105 0.969396 0.290413 0.324893 C++ Note: df106 1.85279 0.371793 1.01567 C++ Note: df501 -5164.534 C++ Note: df504 0.05006156 0.3125659 0.0802485 Warning: model covariate order changed C++ Note: START_POIS_GUESS C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 1 C++ Note: df99,30,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 2 in guess 0 C++ Note: values checked 0.426096 0.646539 0.157278 C++ Note: sums checked 7274.1 7274.1 1341.83 C++ Note: derivs checked 4601.97 23182.6 2733.27 C++ Note: second derivs checked 4601.97 82544.2 8524.37 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 7274.1 1341.83 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 7274.1 1341.83 C++ Note: risk checked 17001 C++ Note: risk1 checked 10706.4 54122.7 19625.6 C++ Note: risk2 checked 10706.4 192502 61415.9 C++ Note: df101 -18942.2 -18942.2 -18942.2 C++ Note: df102 -12053.5 -60927.3 -21843.1 C++ Note: df103 -12141.5 -218114 -69007.6 C++ Note: df104 0.426096 0.646539 0.157278 C++ Note: Checking Deviance 37742.9 C++ Note: df105 0.992752 0.279337 0.316532 C++ Note: df106 1.57151 0.310899 0.867193 C++ Note: Starting Halves C++ Note: df501 -18942.23 C++ Note: df504 0.4260961 0.646539 0.1572781 C++ Note: values checked 0.254195 0.478304 0.123322 C++ Note: sums checked 3900.36 3900.36 1253.74 C++ Note: derivs checked 2309.18 11554.8 2460.98 C++ Note: second derivs checked 2309.18 40015.3 7535.66 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 3900.36 1253.74 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 3900.36 1253.74 C++ Note: risk checked 8783.44 C++ Note: risk1 checked 5182.78 26003.4 9537.67 C++ Note: risk2 checked 5182.78 89978.1 29321.3 C++ Note: df101 -9722.07 -9722.07 -9722.07 C++ Note: df102 -5791.51 -29075 -10520.7 C++ Note: df103 -5879.51 -101991 -32827.7 C++ Note: df104 0.254195 0.478304 0.123322 C++ Note: Checking Deviance 19302.5 C++ Note: df105 0.985033 0.285074 0.320482 C++ Note: df106 1.67868 0.334379 0.924092 C++ Note: df100 2052 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: df100 2101 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: df101 -9722.072 -9722.072 -9722.072 C++ Note: df102 -5791.513 -29075.02 -10520.68 C++ Note: df103 -5879.513 -101991.2 -32827.7 C++ Note: df104 0.2541947 0.4783037 0.1233221 C++ Note: Checking Deviance 19302.54 C++ Note: df105 0.9850328 0.2850738 0.3204818 C++ Note: df106 1.678676 0.3343789 0.9240916 C++ Note: df101 -9722.07 -9722.07 -9722.07 C++ Note: df102 -5791.51 -29075 -10520.7 C++ Note: df103 -5879.51 -101991 -32827.7 C++ Note: df104 0.254195 0.478304 0.123322 C++ Note: Checking Deviance 19302.5 C++ Note: df105 0.985033 0.285074 0.320482 C++ Note: df106 1.67868 0.334379 0.924092 C++ Note: ending guess 0 C++ Note: df501 -9722.072 C++ Note: df504 0.2541947 0.4783037 0.1233221 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.2541947 0.4783037 0.1233221, -9722.072<-- Best Guess C++ Note: starting subterms 2 in best guess 0 C++ Note: values checked 0.254195 0.478304 0.123322 C++ Note: sums checked 3900.36 3900.36 1253.74 C++ Note: derivs checked 2309.18 11554.8 2460.98 C++ Note: second derivs checked 2309.18 40015.3 7535.66 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 3900.36 1253.74 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 3900.36 1253.74 C++ Note: risk checked 8783.44 C++ Note: risk1 checked 5182.78 26003.4 9537.67 C++ Note: risk2 checked 5182.78 89978.1 29321.3 C++ Note: Made Risk Side Lists C++ Note: df101 -9722.07 -9722.07 -9722.07 C++ Note: df102 -5791.51 -29075 -10520.7 C++ Note: df103 -5879.51 -101991 -32827.7 C++ Note: df104 0.254195 0.478304 0.123322 C++ Note: Checking Deviance 19302.5 C++ Note: df105 0.985033 0.285074 0.320482 C++ Note: df106 1.67868 0.334379 0.924092 C++ Note: Starting Halves C++ Note: df501 -9722.072 C++ Note: df504 0.2541947 0.4783037 0.1233221 C++ Note: values checked 0.0500616 0.312566 0.0802485 C++ Note: sums checked 2172.57 2172.57 1154.38 C++ Note: derivs checked 1178.37 5851.84 2160.22 C++ Note: second derivs checked 1178.37 19594.1 6459.87 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked 2172.57 1154.38 C++ Note: LIN_non-dose checked 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 2172.57 1154.38 C++ Note: risk checked 4679.98 C++ Note: risk1 checked 2533.3 12602.3 4687.51 C++ Note: risk2 checked 2533.3 42177.5 14076.6 C++ Note: df101 -5164.53 -5164.53 -5164.53 C++ Note: df102 -2787.43 -13890.9 -5084.88 C++ Note: df103 -2875.43 -47831.4 -15650.9 C++ Note: df104 0.0500616 0.312566 0.0802485 C++ Note: Checking Deviance 10187.5 C++ Note: df105 0.969396 0.290413 0.324893 C++ Note: df106 1.85279 0.371793 1.01567 C++ Note: df100 4634 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: df100 4682 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: df101 -5164.534 -5164.534 -5164.534 C++ Note: df102 -2787.432 -13890.89 -5084.875 C++ Note: df103 -2875.432 -47831.43 -15650.91 C++ Note: df104 0.05006156 0.3125659 0.0802485 C++ Note: Checking Deviance 10187.47 C++ Note: df105 0.9693959 0.2904134 0.3248932 C++ Note: df106 1.852793 0.371793 1.015666 C++ Note: df101 -5164.53 -5164.53 -5164.53 C++ Note: df102 -2787.43 -13890.9 -5084.88 C++ Note: df103 -2875.43 -47831.4 -15650.9 C++ Note: df104 0.0500616 0.312566 0.0802485 C++ Note: Checking Deviance 10187.5 C++ Note: df105 0.969396 0.290413 0.324893 C++ Note: df106 1.85279 0.371793 1.01567 C++ Note: df501 -5164.534 C++ Note: df504 0.05006156 0.3125659 0.0802485 Warning: model covariate order changed C++ Note: START_POIS_GUESS C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 1 C++ Note: df99,29,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 2 in guess 0 C++ Note: values checked -0.1 -0.1 0.2 C++ Note: sums checked -261.4 -261.4 341.682 C++ Note: derivs checked 531 2083 1708.41 C++ Note: second derivs checked 0 0 0 C++ Note: dose checked 1000 1000 C++ Note: non-dose checked -261.4 341.682 C++ Note: LIN_non-dose checked -261.4 341.682 C++ Note: PLIN_non-dose checked 1000 1000 C++ Note: LOGLIN_non-dose checked 1000 1000 C++ Error: A non-positive risk was detected: -1.111148 C++ Warning: final failing values -0.1 -0.1 0.2 C++ Warning: final failing terms lin lin lin Invalid risk Error: Atleast one parameter must be free Note: 2 risk groups C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 1 1 2 C++ Note: df99,33,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 3 C++ Note: values checked 0.1 0.1 0.1 0.1 C++ Note: sums checked 7.420684 1.45 1.45 7.4 C++ Note: dose checked 7 7 7 C++ Note: non-dose checked 7.420684 1.45 7.4 C++ Note: LIN_non-dose checked 7 1.45 7 C++ Note: PLIN_non-dose checked 7 7 7.4 C++ Note: LOGLIN_non-dose checked 7.420684 7 7 C++ Note: df99,296,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:17 2024 Error: no events Error: Atleast one parameter must be free C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 1 1 2 C++ Note: df99,32,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 3 C++ Note: values checked 0.1 0.1 0.1 0.1 C++ Note: sums checked 7.420684 1.45 1.45 7.4 C++ Note: dose checked 7 7 7 C++ Note: non-dose checked 7.420684 1.45 7.4 C++ Note: LIN_non-dose checked 7 1.45 7 C++ Note: PLIN_non-dose checked 7 7 7.4 C++ Note: LOGLIN_non-dose checked 7.420684 7 7 C++ Note: df99,293,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:17 2024 Error: no events Error: Atleast one parameter must be free C++ Note: START_PLOT C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 C++ Note: df99,27,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: values checked 0.1 -0.1 C++ Note: sums checked 4.33113 4.33113 C++ Note: dose checked 7 C++ Note: non-dose checked 4.33113 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 4.33113 C++ Note: risk checked 4.33113 Error: Atleast one parameter must be free Note: Starting Plot Function Note: Getting Plot Info Note: 2 risk groups Warning: model covariate order changed Note: 2 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Grouping Start C++ Note: df100 82 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked 0.1 -0.1 C++ Note: sums checked 4.33113 4.33113 C++ Note: derivs checked 4.33113 24.2686 C++ Note: second derivs checked 4.33113 152.884 C++ Note: dose checked 7 C++ Note: non-dose checked 4.33113 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 4.33113 C++ Note: risk checked 4.33113 C++ Note: risk1 checked 4.33113 24.2686 C++ Note: risk2 checked 4.33113 152.884 C++ Note: Made Risk Side Lists C++ Note: riskr checked 1.2374 C++ Note: risk1r checked 1.2374 6.93596 C++ Note: risk2r checked 1.2374 43.6346 C++ Note: riskl checked 1.2374 C++ Note: risk1l checked 1.2374 6.93596 C++ Note: risk2l checked 1.2374 43.6346 C++ Note: df101 0 0 C++ Note: df102 0 0 C++ Note: df103 0 0 C++ Note: df104 0.1 -0.1 C++ Note: df105 nan nan C++ Note: df106 nan nan C++ Note: riskr checked 1.2374 C++ Note: risk1r checked 1.2374 6.93596 C++ Note: risk2r checked 1.2374 43.6346 C++ Note: riskl checked 1.2374 C++ Note: risk1l checked 1.2374 6.93596 C++ Note: risk2l checked 1.2374 43.6346 C++ Note: df101 0 0 C++ Note: df102 0 0 C++ Note: df103 0 0 C++ Note: df104 0.1 -0.1 C++ Note: df105 nan nan C++ Note: df106 nan nan C++ Note: ending guess 0 C++ Note: df501 0 C++ Note: df504 0.1 -0.1 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.1 -0.1, 0<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0.1 -0.1 C++ Note: sums checked 4.33113 4.33113 C++ Note: derivs checked 4.33113 24.2686 C++ Note: second derivs checked 4.33113 152.884 C++ Note: dose checked 7 C++ Note: non-dose checked 4.33113 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 4.33113 C++ Note: risk checked 4.33113 C++ Note: risk1 checked 4.33113 24.2686 C++ Note: risk2 checked 4.33113 152.884 C++ Note: Made Risk Side Lists C++ Note: riskr checked 1.2374 C++ Note: risk1r checked 1.2374 6.93596 C++ Note: risk2r checked 1.2374 43.6346 C++ Note: riskl checked 1.2374 C++ Note: risk1l checked 1.2374 6.93596 C++ Note: risk2l checked 1.2374 43.6346 C++ Note: df101 0 0 C++ Note: df102 0 0 C++ Note: df103 0 0 C++ Note: df104 0.1 -0.1 C++ Note: df105 nan nan C++ Note: df106 nan nan C++ Note: riskr checked 1.2374 C++ Note: risk1r checked 1.2374 6.93596 C++ Note: risk2r checked 1.2374 43.6346 C++ Note: riskl checked 1.2374 C++ Note: risk1l checked 1.2374 6.93596 C++ Note: risk2l checked 1.2374 43.6346 C++ Note: df101 0 0 C++ Note: df102 0 0 C++ Note: df103 0 0 C++ Note: df104 0.1 -0.1 C++ Note: df105 nan nan C++ Note: df106 nan nan C++ Note: Exiting Regression C++ Note: df501 0 C++ Note: df504 0.1 -0.1 Note: starting ph_plot Note: nonStratified survival curve calculation C++ Note: START_PLOT C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: values checked -0.1 0.1 C++ Note: sums checked 4.33113 4.33113 C++ Note: derivs checked 24.2686 4.33113 C++ Note: second derivs checked 152.884 4.33113 C++ Note: dose checked 7 C++ Note: non-dose checked 4.33113 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 4.33113 C++ Note: risk checked 4.33113 C++ Note: risk1 checked 24.2686 4.33113 C++ Note: risk2 checked 152.884 4.33113 C++ Note: Grouping Start C++ Note: df100 353 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Made Risk Side Lists C++ Note: riskr checked 1.2374 C++ Note: risk1r checked 6.93596 1.2374 C++ Note: risk2r checked 43.6346 1.2374 C++ Note: riskl checked 1.2374 C++ Note: risk1l checked 6.93596 1.2374 C++ Note: risk2l checked 43.6346 1.2374 C++ Note: df101 0 0 C++ Note: df102 0 0 C++ Note: df103 0 0 C++ Note: df104 -0.1 0.1 C++ Note: df105 nan nan C++ Note: df106 nan nan Note: writing survival data Note: Plotting Martingale Residuals Note: Martingale Plot: d Saving 7 x 7 in image Saving 7 x 7 in image Note: Starting Plot Function Note: Getting Plot Info Note: 2 risk groups Note: Starting Plot Function Note: Getting Plot Info Error: no events Error: Atleast one parameter must be free Warning: rmin/rmax not equal size, lin/loglin min/max used Warning: rmin and rmax lists not equal size, defaulting to lin and loglin min/max values C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 C++ Note: df99,24,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 1 C++ Note: values checked 0.01 C++ Note: sums checked 6437.949 C++ Note: dose checked 6400 C++ Note: non-dose checked 6437.949 C++ Note: LIN_non-dose checked 6400 C++ Note: PLIN_non-dose checked 6400 C++ Note: LOGLIN_non-dose checked 6437.949 C++ Note: df99,428,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:17 2024 Note: 86 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 C++ Note: df99,22,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Grouping Start C++ Note: df100 1270 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked 0.01 C++ Note: sums checked 6437.95 C++ Note: derivs checked 3813.95 C++ Note: second derivs checked 3813.95 C++ Note: dose checked 6400 C++ Note: non-dose checked 6437.95 C++ Note: LIN_non-dose checked 6400 C++ Note: PLIN_non-dose checked 6400 C++ Note: LOGLIN_non-dose checked 6437.95 C++ Note: risk checked 6437.95 C++ Note: risk1 checked 3813.95 C++ Note: risk2 checked 3813.95 C++ Note: Made Risk Side Lists C++ Note: riskr checked 4185.37 C++ Note: risk1r checked 2549.37 C++ Note: risk2r checked 2549.37 C++ Note: riskl checked 86.3317 C++ Note: risk1l checked 33.3317 C++ Note: risk2l checked 33.3317 C++ Note: df101 -313.163 C++ Note: df102 -21.7172 C++ Note: df103 -19.4313 C++ Note: df104 0.01 C++ Note: df105 1.11764 C++ Note: df106 14.42 C++ Note: Starting Halves C++ Note: df501 -313.1627 C++ Note: df504 0.01 C++ Note: values checked -0.828233 C++ Note: sums checked 4273.43 C++ Note: derivs checked 1649.43 C++ Note: second derivs checked 1649.43 C++ Note: dose checked 6400 C++ Note: non-dose checked 4273.43 C++ Note: LIN_non-dose checked 6400 C++ Note: PLIN_non-dose checked 6400 C++ Note: LOGLIN_non-dose checked 4273.43 C++ Note: risk checked 4273.43 C++ Note: risk1 checked 1649.43 C++ Note: risk2 checked 1649.43 C++ Note: riskr checked 2738.53 C++ Note: risk1r checked 1102.53 C++ Note: risk2r checked 1102.53 C++ Note: riskl checked 67.4151 C++ Note: risk1l checked 14.4151 C++ Note: risk2l checked 14.4151 C++ Note: df101 -302.091 C++ Note: df102 -4.55996 C++ Note: df103 -20.4044 C++ Note: df104 -0.828233 C++ Note: df105 0.22348 C++ Note: df106 66.2487 C++ Note: df100 3956 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Starting Halves C++ Note: df501 -302.0913 C++ Note: df504 -0.828233 C++ Note: values checked -0.995843 C++ Note: sums checked 4018.9 C++ Note: derivs checked 1394.9 C++ Note: second derivs checked 1394.9 C++ Note: dose checked 6400 C++ Note: non-dose checked 4018.9 C++ Note: LIN_non-dose checked 6400 C++ Note: PLIN_non-dose checked 6400 C++ Note: LOGLIN_non-dose checked 4018.9 C++ Note: risk checked 4018.9 C++ Note: risk1 checked 1394.9 C++ Note: risk2 checked 1394.9 C++ Note: riskr checked 2568.4 C++ Note: risk1r checked 932.396 C++ Note: risk2r checked 932.396 C++ Note: riskl checked 65.1906 C++ Note: risk1l checked 12.1906 C++ Note: risk2l checked 12.1906 C++ Note: df101 -301.611 C++ Note: df102 -1.18635 C++ Note: df103 -19.8114 C++ Note: df104 -0.995843 C++ Note: df105 0.0598821 C++ Note: df106 254.236 C++ Note: df100 5163 1 2 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Starting Halves C++ Note: df501 -301.6112 C++ Note: df504 -0.9958427 C++ Note: values checked -1.04075 C++ Note: sums checked 3957.64 C++ Note: derivs checked 1333.64 C++ Note: second derivs checked 1333.64 C++ Note: dose checked 6400 C++ Note: non-dose checked 3957.64 C++ Note: LIN_non-dose checked 6400 C++ Note: PLIN_non-dose checked 6400 C++ Note: LOGLIN_non-dose checked 3957.64 C++ Note: risk checked 3957.64 C++ Note: risk1 checked 1333.64 C++ Note: risk2 checked 1333.64 C++ Note: riskr checked 2527.45 C++ Note: risk1r checked 891.447 C++ Note: risk2r checked 891.447 C++ Note: riskl checked 64.6552 C++ Note: risk1l checked 11.6552 C++ Note: risk2l checked 11.6552 C++ Note: df101 -301.578 C++ Note: df102 -0.300978 C++ Note: df103 -19.6132 C++ Note: df104 -1.04075 C++ Note: df105 0.0153457 C++ Note: df106 1001.99 C++ Note: df100 6352 1 3 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Starting Halves C++ Note: df501 -301.5778 C++ Note: df504 -1.040754 C++ Note: values checked -1.05226 C++ Note: sums checked 3942.38 C++ Note: derivs checked 1318.38 C++ Note: second derivs checked 1318.38 C++ Note: dose checked 6400 C++ Note: non-dose checked 3942.38 C++ Note: LIN_non-dose checked 6400 C++ Note: PLIN_non-dose checked 6400 C++ Note: LOGLIN_non-dose checked 3942.38 C++ Note: risk checked 3942.38 C++ Note: risk1 checked 1318.38 C++ Note: risk2 checked 1318.38 C++ Note: riskr checked 2517.25 C++ Note: risk1r checked 881.246 C++ Note: risk2r checked 881.246 C++ Note: riskl checked 64.5218 C++ Note: risk1l checked 11.5218 C++ Note: risk2l checked 11.5218 C++ Note: df101 -301.576 C++ Note: df102 -0.0755501 C++ Note: df103 -19.5599 C++ Note: df104 -1.05226 C++ Note: df105 0.0038625 C++ Note: df106 3991.73 C++ Note: df100 7546 1 4 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Starting Halves C++ Note: df501 -301.5756 C++ Note: df504 -1.052263 C++ Note: values checked -1.05516 C++ Note: sums checked 3938.56 C++ Note: derivs checked 1314.56 C++ Note: second derivs checked 1314.56 C++ Note: dose checked 6400 C++ Note: non-dose checked 3938.56 C++ Note: LIN_non-dose checked 6400 C++ Note: PLIN_non-dose checked 6400 C++ Note: LOGLIN_non-dose checked 3938.56 C++ Note: risk checked 3938.56 C++ Note: risk1 checked 1314.56 C++ Note: risk2 checked 1314.56 C++ Note: riskr checked 2514.7 C++ Note: risk1r checked 878.697 C++ Note: risk2r checked 878.697 C++ Note: riskl checked 64.4885 C++ Note: risk1l checked 11.4885 C++ Note: risk2l checked 11.4885 C++ Note: df101 -301.576 C++ Note: df102 -0.0189072 C++ Note: df103 -19.5463 C++ Note: df104 -1.05516 C++ Note: df105 0.0009673 C++ Note: df106 15950.3 C++ Note: df100 8766 1 5 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: riskr checked 2514.7 C++ Note: risk1r checked 878.697 C++ Note: risk2r checked 878.697 C++ Note: riskl checked 64.4885 C++ Note: risk1l checked 11.4885 C++ Note: risk2l checked 11.4885 C++ Note: df101 -301.576 C++ Note: df102 -0.0189072 C++ Note: df103 -19.5463 C++ Note: df104 -1.05516 C++ Note: df105 0.0009673 C++ Note: df106 15950.3 C++ Note: ending guess 0 C++ Note: df501 -301.5755 C++ Note: df504 -1.05516 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -1.05516, -301.5755<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -1.05516 C++ Note: sums checked 3938.56 C++ Note: derivs checked 1314.56 C++ Note: second derivs checked 1314.56 C++ Note: dose checked 6400 C++ Note: non-dose checked 3938.56 C++ Note: LIN_non-dose checked 6400 C++ Note: PLIN_non-dose checked 6400 C++ Note: LOGLIN_non-dose checked 3938.56 C++ Note: risk checked 3938.56 C++ Note: risk1 checked 1314.56 C++ Note: risk2 checked 1314.56 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2514.7 C++ Note: risk1r checked 878.697 C++ Note: risk2r checked 878.697 C++ Note: riskl checked 64.4885 C++ Note: risk1l checked 11.4885 C++ Note: risk2l checked 11.4885 C++ Note: df101 -301.576 C++ Note: df102 -0.0189072 C++ Note: df103 -19.5463 C++ Note: df104 -1.05516 C++ Note: df105 0.0009673 C++ Note: df106 15950.3 C++ Note: Starting Halves C++ Note: df501 -301.5755 C++ Note: df504 -1.05516 C++ Note: values checked -1.05589 C++ Note: sums checked 3937.61 C++ Note: derivs checked 1313.61 C++ Note: second derivs checked 1313.61 C++ Note: dose checked 6400 C++ Note: non-dose checked 3937.61 C++ Note: LIN_non-dose checked 6400 C++ Note: PLIN_non-dose checked 6400 C++ Note: LOGLIN_non-dose checked 3937.61 C++ Note: risk checked 3937.61 C++ Note: risk1 checked 1313.61 C++ Note: risk2 checked 1313.61 C++ Note: riskr checked 2514.06 C++ Note: risk1r checked 878.06 C++ Note: risk2r checked 878.06 C++ Note: riskl checked 64.4802 C++ Note: risk1l checked 11.4802 C++ Note: risk2l checked 11.4802 C++ Note: df101 -301.575 C++ Note: df102 -0.00472803 C++ Note: df103 -19.5429 C++ Note: df104 -1.05589 C++ Note: df105 0.00024193 C++ Note: df106 63784.6 C++ Note: df100 11422 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: riskr checked 2514.06 C++ Note: risk1r checked 878.06 C++ Note: risk2r checked 878.06 C++ Note: riskl checked 64.4802 C++ Note: risk1l checked 11.4802 C++ Note: risk2l checked 11.4802 C++ Note: df101 -301.575 C++ Note: df102 -0.00472803 C++ Note: df103 -19.5429 C++ Note: df104 -1.05589 C++ Note: df105 0.00024193 C++ Note: df106 63784.6 C++ Note: riskr checked 2514.06 C++ Note: risk1r checked 878.06 C++ Note: risk2r checked 878.06 C++ Note: riskl checked 64.4802 C++ Note: risk1l checked 11.4802 C++ Note: risk2l checked 11.4802 C++ Note: df101 -301.575 C++ Note: df102 -0.00472803 C++ Note: df103 -19.5429 C++ Note: df104 -1.05589 C++ Note: df105 0.00024193 C++ Note: df106 63784.6 C++ Note: Exiting Regression C++ Note: df501 -301.5755 C++ Note: df504 -1.055886 Warning: rmin and rmax lists not equal size, defaulting to lin and loglin min/max values C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 1 C++ Note: df99,24,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 2 C++ Note: values checked -1.055886 -15 C++ Note: sums checked 3937.61 0.001957775 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 3937.61 0.001957775 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 3937.61 0.001957775 C++ Note: df99,1371,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:17 2024 Note: 86 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 1 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Grouping Start C++ Note: df100 1577 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 2 in guess 0 C++ Note: values checked -1.05589 -15 C++ Note: sums checked 3937.61 0.00195777 C++ Note: derivs checked 1313.61 0.00195777 C++ Note: second derivs checked 1313.61 0.00195777 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 3937.61 0.00195777 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 3937.61 0.00195777 C++ Note: risk checked 3937.61 C++ Note: risk1 checked 1313.61 0.00120452 C++ Note: risk2 checked 1313.61 0.00120452 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2514.06 C++ Note: risk1r checked 878.06 0.000769057 C++ Note: risk2r checked 878.06 0.000769057 C++ Note: riskl checked 64.4802 C++ Note: risk1l checked 11.4802 1.97246e-05 C++ Note: risk2l checked 11.4802 1.97246e-05 C++ Note: df101 -301.575 -301.575 C++ Note: df102 -0.00472803 -3.70577e-21 C++ Note: df103 -19.5429 -3.70577e-21 C++ Note: df104 -1.05589 -15 C++ Note: df105 0.00024193 1 C++ Note: df106 63784.6 8.138e+22 C++ Note: Starting Halves C++ Note: df501 -301.5755 C++ Note: df504 -1.055886 -15 C++ Note: values checked -1.05607 -15 C++ Note: sums checked 3937.37 0.00195777 C++ Note: derivs checked 1313.37 0.00195777 C++ Note: second derivs checked 1313.37 0.00195777 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 3937.37 0.00195777 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 3937.37 0.00195777 C++ Note: risk checked 3937.37 C++ Note: risk1 checked 1313.37 0.00120445 C++ Note: risk2 checked 1313.37 0.00120445 C++ Note: riskr checked 2513.9 C++ Note: risk1r checked 877.901 0.000769008 C++ Note: risk2r checked 877.901 0.000769008 C++ Note: riskl checked 64.4781 C++ Note: risk1l checked 11.4781 1.9724e-05 C++ Note: risk2l checked 11.4781 1.9724e-05 C++ Note: df101 -301.575 -301.575 C++ Note: df102 -0.00118208 -4.60574e-21 C++ Note: df103 -19.5421 -6.29981e-21 C++ Note: df104 -1.05607 -15 C++ Note: df105 6.04892e-05 0.731092 C++ Note: df106 255122 6.54782e+22 C++ Note: df100 5786 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: riskr checked 2513.9 C++ Note: risk1r checked 877.901 0.000769008 C++ Note: risk2r checked 877.901 0.000769008 C++ Note: riskl checked 64.4781 C++ Note: risk1l checked 11.4781 1.9724e-05 C++ Note: risk2l checked 11.4781 1.9724e-05 C++ Note: df101 -301.575 -301.575 C++ Note: df102 -0.00118208 -4.60574e-21 C++ Note: df103 -19.5421 -6.29981e-21 C++ Note: df104 -1.05607 -15 C++ Note: df105 6.04892e-05 0.731092 C++ Note: df106 255122 6.54782e+22 C++ Note: ending guess 0 C++ Note: df501 -301.5755 C++ Note: df504 -1.056067 -15 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -1.056067 -15, -301.5755<-- Best Guess C++ Note: starting subterms 2 in best guess 0 C++ Note: values checked -1.05607 -15 C++ Note: sums checked 3937.37 0.00195777 C++ Note: derivs checked 1313.37 0.00195777 C++ Note: second derivs checked 1313.37 0.00195777 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 3937.37 0.00195777 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 3937.37 0.00195777 C++ Note: risk checked 3937.37 C++ Note: risk1 checked 1313.37 0.00120445 C++ Note: risk2 checked 1313.37 0.00120445 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2513.9 C++ Note: risk1r checked 877.901 0.000769008 C++ Note: risk2r checked 877.901 0.000769008 C++ Note: riskl checked 64.4781 C++ Note: risk1l checked 11.4781 1.9724e-05 C++ Note: risk2l checked 11.4781 1.9724e-05 C++ Note: df101 -301.575 -301.575 C++ Note: df102 -0.00118208 -4.60574e-21 C++ Note: df103 -19.5421 -6.29981e-21 C++ Note: df104 -1.05607 -15 C++ Note: df105 6.04892e-05 0.731092 C++ Note: df106 255122 6.54782e+22 C++ Note: Starting Halves C++ Note: df501 -301.5755 C++ Note: df504 -1.056067 -15 C++ Note: values checked -1.05611 -15 C++ Note: sums checked 3937.31 0.00195777 C++ Note: derivs checked 1313.31 0.00195777 C++ Note: second derivs checked 1313.31 0.00195777 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 3937.31 0.00195777 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 3937.31 0.00195777 C++ Note: risk checked 3937.31 C++ Note: risk1 checked 1313.31 0.00120443 C++ Note: risk2 checked 1313.31 0.00120443 C++ Note: riskr checked 2513.86 C++ Note: risk1r checked 877.861 0.000768996 C++ Note: risk2r checked 877.861 0.000768996 C++ Note: riskl checked 64.4776 C++ Note: risk1l checked 11.4776 1.97238e-05 C++ Note: risk2l checked 11.4776 1.97238e-05 C++ Note: df101 -301.575 -301.575 C++ Note: df102 -0.000295526 5.98217e-21 C++ Note: df103 -19.5419 5.82335e-21 C++ Note: df104 -1.05611 -15 C++ Note: df105 1.51227e-05 1.02727 C++ Note: df106 1.02047e+06 -5.04124e+22 C++ Note: df100 10455 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: riskr checked 2513.86 C++ Note: risk1r checked 877.861 0.000768996 C++ Note: risk2r checked 877.861 0.000768996 C++ Note: riskl checked 64.4776 C++ Note: risk1l checked 11.4776 1.97238e-05 C++ Note: risk2l checked 11.4776 1.97238e-05 C++ Note: df101 -301.575 -301.575 C++ Note: df102 -0.000295526 5.98217e-21 C++ Note: df103 -19.5419 5.82335e-21 C++ Note: df104 -1.05611 -15 C++ Note: df105 1.51227e-05 1.02727 C++ Note: df106 1.02047e+06 -5.04124e+22 C++ Note: riskr checked 2513.86 C++ Note: risk1r checked 877.861 0.000768996 C++ Note: risk2r checked 877.861 0.000768996 C++ Note: riskl checked 64.4776 C++ Note: risk1l checked 11.4776 1.97238e-05 C++ Note: risk2l checked 11.4776 1.97238e-05 C++ Note: df101 -301.575 -301.575 C++ Note: df102 -0.000295526 5.98217e-21 C++ Note: df103 -19.5419 5.82335e-21 C++ Note: df104 -1.05611 -15 C++ Note: df105 1.51227e-05 1.02727 C++ Note: df106 1.02047e+06 -5.04124e+22 C++ Note: Exiting Regression C++ Note: df501 -301.5755 C++ Note: df504 -1.056113 -15 Error: guesses_control and model_control have different strata options Note: 2 strata used Note: 86 risk groups Warning: rmin and rmax lists not equal size, defaulting to lin and loglin min/max values C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 1 C++ Note: df99,24,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 2 C++ Note: values checked 0.01 -15 C++ Note: sums checked 6437.949 0.001957775 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6437.949 0.001957775 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6437.949 0.001957775 C++ Note: df99,436,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:17 2024 Note: 1 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 1 C++ Note: df99,24,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 2 C++ Note: values checked -0.4291924 -15.30179 C++ Note: sums checked 5082.307 0.001447756 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 5082.307 0.001447756 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 5082.307 0.001447756 C++ Note: df99,421,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:17 2024 Note: 2 strata used Note: 86 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 1 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Grouping Start C++ Note: df100 1873 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 2 in guess 0 C++ Note: values checked 0.01 -15 C++ Note: sums checked 6437.95 0.00195777 C++ Note: derivs checked 3813.95 0.00195777 C++ Note: second derivs checked 3813.95 0.00195777 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6437.95 0.00195777 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6437.95 0.00195777 C++ Note: risk checked 6437.95 C++ Note: risk1 checked 3813.95 0.00196938 C++ Note: risk2 checked 3813.95 0.00196938 C++ Note: Made Risk Side Lists C++ Note: riskr checked 1135 832.282 C++ Note: riskl checked 53 33.3317 C++ Note: df101 -248.958 -248.958 C++ Note: df102 2.22045e-16 -1.53525e-21 C++ Note: df103 -2.22045e-16 -1.53525e-21 C++ Note: df104 0.01 -15 C++ Note: df105 -1 1 C++ Note: df106 -1.12121e+18 1.62162e+23 C++ Note: Starting Halves C++ Note: df501 -248.9581 C++ Note: df504 0.01 -15 C++ Note: values checked 0.76 -15.8017 C++ Note: sums checked 10698.1 0.00087817 C++ Note: derivs checked 8074.13 0.00087817 C++ Note: second derivs checked 8074.13 0.00087817 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 10698.1 0.00087817 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 10698.1 0.00087817 C++ Note: risk checked 10698.1 C++ Note: risk1 checked 8074.14 0.00146793 C++ Note: risk2 checked 8074.14 0.00146793 C++ Note: riskr checked 1135 1761.94 C++ Note: riskl checked 53 70.5632 C++ Note: df101 -248.958 -248.958 C++ Note: df102 8.88178e-16 -1.1382e-21 C++ Note: df103 -8.88178e-16 -1.1382e-21 C++ Note: df104 0.76 -15.8017 C++ Note: df105 -1 1 C++ Note: df106 -2.80302e+17 2.1873e+23 C++ Note: df100 7129 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: values checked 0.385 -15.4009 C++ Note: sums checked 8173.26 0.0013112 C++ Note: derivs checked 5549.26 0.0013112 C++ Note: second derivs checked 5549.26 0.0013112 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 8173.26 0.0013112 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 8173.26 0.0013112 C++ Note: risk checked 8173.27 C++ Note: risk1 checked 5549.27 0.0016745 C++ Note: risk2 checked 5549.27 0.0016745 C++ Note: riskr checked 1135 1210.96 C++ Note: riskl checked 53 48.4973 C++ Note: df101 -248.958 -248.958 C++ Note: df102 3.33067e-16 -2.30287e-21 C++ Note: df103 -3.33067e-16 -2.30287e-21 C++ Note: df104 0.385 -15.4009 C++ Note: df105 -1 1 C++ Note: df106 -7.47472e+17 1.08108e+23 C++ Note: df100 9686 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: riskr checked 1135 1210.96 C++ Note: riskl checked 53 48.4973 C++ Note: df101 -248.958 -248.958 C++ Note: df102 3.33067e-16 -2.30287e-21 C++ Note: df103 -3.33067e-16 -2.30287e-21 C++ Note: df104 0.385 -15.4009 C++ Note: df105 -1 1 C++ Note: df106 -7.47472e+17 1.08108e+23 C++ Note: ending guess 0 C++ Note: df501 -248.9581 C++ Note: df504 0.3850002 -15.40086 C++ Note: starting subterms 2 in guess 1 C++ Note: values checked -0.429192 -15.3018 C++ Note: sums checked 5082.31 0.00144776 C++ Note: derivs checked 2458.31 0.00144776 C++ Note: second derivs checked 2458.31 0.00144776 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 5082.31 0.00144776 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 5082.31 0.00144776 C++ Note: risk checked 5082.31 C++ Note: risk1 checked 2458.31 0.00114968 C++ Note: risk2 checked 2458.31 0.00114968 C++ Note: Made Risk Side Lists C++ Note: riskr checked 1135 536.453 C++ Note: riskl checked 53 21.4841 C++ Note: df101 -248.958 -248.958 C++ Note: df102 5.55112e-16 -3.70577e-22 C++ Note: df103 -5.55112e-16 -3.70577e-22 C++ Note: df104 -0.429192 -15.3018 C++ Note: df105 -1 1 C++ Note: df106 -4.48483e+17 6.71812e+23 C++ Note: Starting Halves C++ Note: df501 -248.9581 C++ Note: df504 0.3850002 -15.40086 C++ Note: values checked 0.320808 -16.3018 C++ Note: sums checked 7828.24 0.0005326 C++ Note: derivs checked 5204.24 0.0005326 C++ Note: second derivs checked 5204.24 0.0005326 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 7828.24 0.0005326 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 7828.24 0.0005326 C++ Note: risk checked 7828.24 C++ Note: risk1 checked 5204.24 0.000651456 C++ Note: risk2 checked 5204.24 0.000651456 C++ Note: riskr checked 1135 1135.67 C++ Note: riskl checked 53 45.4819 C++ Note: df101 -248.958 -248.958 C++ Note: df102 3.33067e-16 4.49986e-22 C++ Note: df103 -3.33067e-16 4.49986e-22 C++ Note: df104 0.320808 -16.3018 C++ Note: df105 -1 1 C++ Note: df106 -7.47472e+17 -5.53257e+23 C++ Note: df100 16002 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: values checked -0.0541923 -15.8018 C++ Note: sums checked 6200.82 0.000878109 C++ Note: derivs checked 3576.82 0.000878109 C++ Note: second derivs checked 3576.82 0.000878109 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 6200.82 0.000878109 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 6200.82 0.000878109 C++ Note: risk checked 6200.82 C++ Note: risk1 checked 3576.82 0.00085078 C++ Note: risk2 checked 3576.82 0.00085078 C++ Note: riskr checked 1135 780.534 C++ Note: riskl checked 53 31.2593 C++ Note: df101 -248.958 -248.958 C++ Note: df102 -3.33067e-15 -1.05879e-21 C++ Note: df103 3.33067e-15 -9.52912e-22 C++ Note: df104 -0.0541923 -15.8018 C++ Note: df105 -1 1.11111 C++ Note: df106 7.47472e+16 2.35134e+23 C++ Note: df100 18546 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: values checked -0.241692 -15.5518 C++ Note: sums checked 5589.28 0.00112751 C++ Note: derivs checked 2965.28 0.00112751 C++ Note: second derivs checked 2965.28 0.00112751 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 5589.28 0.00112751 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 5589.28 0.00112751 C++ Note: risk checked 5589.29 C++ Note: risk1 checked 2965.28 0.000984687 C++ Note: risk2 checked 2965.28 0.000984687 C++ Note: riskr checked 1135 647.085 C++ Note: riskl checked 53 25.9148 C++ Note: df101 -248.958 -248.958 C++ Note: df102 4.21885e-15 2.35581e-21 C++ Note: df103 -7.99361e-15 2.35581e-21 C++ Note: df104 -0.241692 -15.5518 C++ Note: df105 -0.527778 1 C++ Note: df106 -5.90109e+16 -1.05678e+23 C++ Note: df100 21128 3 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: values checked -0.335442 -15.4268 C++ Note: sums checked 5323.92 0.00127764 C++ Note: derivs checked 2699.92 0.00127764 C++ Note: second derivs checked 2699.92 0.00127764 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 5323.92 0.00127764 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 5323.92 0.00127764 C++ Note: risk checked 5323.92 C++ Note: risk1 checked 2699.92 0.00106282 C++ Note: risk2 checked 2699.92 0.00106282 C++ Note: riskr checked 1135 589.178 C++ Note: riskl checked 53 23.5957 C++ Note: df101 -248.958 -248.958 C++ Note: df102 3.33067e-16 1.16467e-21 C++ Note: df103 -3.33067e-16 1.6676e-21 C++ Note: df104 -0.335442 -15.4268 C++ Note: df105 -1 0.698413 C++ Note: df106 -7.47472e+17 -2.13758e+23 C++ Note: df100 23670 4 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: values checked -0.382317 -15.3643 C++ Note: sums checked 5200.28 0.00136004 C++ Note: derivs checked 2576.28 0.00136004 C++ Note: second derivs checked 2576.28 0.00136004 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 5200.28 0.00136004 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 5200.28 0.00136004 C++ Note: risk checked 5200.28 C++ Note: risk1 checked 2576.28 0.00110509 C++ Note: risk2 checked 2576.28 0.00110509 C++ Note: riskr checked 1135 562.198 C++ Note: riskl checked 53 22.5152 C++ Note: df101 -248.958 -248.958 C++ Note: df102 5.55112e-16 -1.21761e-21 C++ Note: df103 -5.55112e-16 -1.21761e-21 C++ Note: df104 -0.382317 -15.3643 C++ Note: df105 -1 1 C++ Note: df106 -4.48483e+17 2.04465e+23 C++ Note: df100 26216 5 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Changing back to best C++ Note: values checked -0.429192 -15.3018 C++ Note: sums checked 5082.31 0.00144776 C++ Note: derivs checked 2458.31 0.00144776 C++ Note: second derivs checked 2458.31 0.00144776 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 5082.31 0.00144776 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 5082.31 0.00144776 C++ Note: risk checked 5082.31 C++ Note: risk1 checked 2458.31 0.00114968 C++ Note: risk2 checked 2458.31 0.00114968 C++ Note: riskr checked 1135 536.453 C++ Note: riskl checked 53 21.4841 C++ Note: df101 -248.958 -248.958 C++ Note: df102 5.55112e-16 -3.70577e-22 C++ Note: df103 -5.55112e-16 -3.70577e-22 C++ Note: df104 -0.429192 -15.3018 C++ Note: df105 -1 1 C++ Note: df106 -4.48483e+17 6.71812e+23 C++ Note: ending guess 1 C++ Note: df501 -248.9581 C++ Note: df504 0.3850002 -15.40086 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.3850002 -15.40086, -248.9581<-- Best Guess 1, -0.4291924 -15.30179, -248.9581 C++ Note: starting subterms 2 in best guess 0 C++ Note: values checked 0.385 -15.4009 C++ Note: sums checked 8173.26 0.0013112 C++ Note: derivs checked 5549.26 0.0013112 C++ Note: second derivs checked 5549.26 0.0013112 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 8173.26 0.0013112 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 8173.26 0.0013112 C++ Note: risk checked 8173.27 C++ Note: risk1 checked 5549.27 0.0016745 C++ Note: risk2 checked 5549.27 0.0016745 C++ Note: Made Risk Side Lists C++ Note: riskr checked 1135 1210.96 C++ Note: riskl checked 53 48.4973 C++ Note: df101 -248.958 -248.958 C++ Note: df102 3.33067e-16 -2.30287e-21 C++ Note: df103 -3.33067e-16 -2.30287e-21 C++ Note: df104 0.385 -15.4009 C++ Note: df105 -1 1 C++ Note: df106 -7.47472e+17 1.08108e+23 C++ Note: Starting Halves C++ Note: df501 -248.9581 C++ Note: df504 0.3850002 -15.40086 C++ Note: values checked 1.135 -16.1767 C++ Note: sums checked 14371.8 0.000603557 C++ Note: derivs checked 11747.8 0.000603557 C++ Note: second derivs checked 11747.8 0.000603557 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 14371.8 0.000603557 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 14371.8 0.000603557 C++ Note: risk checked 14371.8 C++ Note: risk1 checked 11747.8 0.00135534 C++ Note: risk2 checked 11747.8 0.00135534 C++ Note: riskr checked 1135 2563.61 C++ Note: riskl checked 53 102.669 C++ Note: df101 -248.958 -248.958 C++ Note: df102 5.55112e-16 -7.94093e-23 C++ Note: df103 -5.55112e-16 9.26442e-23 C++ Note: df104 1.135 -16.1767 C++ Note: df105 -1 -0.857143 C++ Note: df106 -4.48483e+17 3.13512e+24 C++ Note: df100 33929 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: values checked 0.76 -15.7888 C++ Note: sums checked 10698.1 0.000889599 C++ Note: derivs checked 8074.13 0.000889599 C++ Note: second derivs checked 8074.13 0.000889599 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 10698.1 0.000889599 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 10698.1 0.000889599 C++ Note: risk checked 10698.1 C++ Note: risk1 checked 8074.13 0.00148704 C++ Note: risk2 checked 8074.13 0.00148704 C++ Note: riskr checked 1135 1761.94 C++ Note: riskl checked 53 70.5631 C++ Note: df101 -248.958 -248.958 C++ Note: df102 4.44089e-16 -4.76456e-22 C++ Note: df103 -4.44089e-16 1.58819e-22 C++ Note: df104 0.76 -15.7888 C++ Note: df105 -1 -3 C++ Note: df106 -5.60604e+17 5.22521e+23 C++ Note: df100 36462 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: values checked 0.5725 -15.5948 C++ Note: sums checked 9317.69 0.00108002 C++ Note: derivs checked 6693.69 0.00108002 C++ Note: second derivs checked 6693.69 0.00108002 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 9317.69 0.00108002 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 9317.69 0.00108002 C++ Note: risk checked 9317.69 C++ Note: risk1 checked 6693.69 0.00157239 C++ Note: risk2 checked 6693.69 0.00157239 C++ Note: riskr checked 1135 1460.7 C++ Note: riskl checked 53 58.4989 C++ Note: df101 -248.958 -248.958 C++ Note: df102 -3.66374e-15 4.76456e-22 C++ Note: df103 4.55191e-15 1.79995e-21 C++ Note: df104 0.5725 -15.5948 C++ Note: df105 -0.804878 0.264706 C++ Note: df106 6.7952e+16 -5.22521e+23 C++ Note: df100 39009 3 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: values checked 0.47875 -15.4978 C++ Note: sums checked 8718.68 0.00119001 C++ Note: derivs checked 6094.68 0.00119001 C++ Note: second derivs checked 6094.68 0.00119001 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 8718.68 0.00119001 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 8718.68 0.00119001 C++ Note: risk checked 8718.68 C++ Note: risk1 checked 6094.68 0.00162115 C++ Note: risk2 checked 6094.68 0.00162115 C++ Note: riskr checked 1135 1329.98 C++ Note: riskl checked 53 53.2639 C++ Note: df101 -248.958 -248.958 C++ Note: df102 4.44089e-16 -6.88214e-22 C++ Note: df103 -4.44089e-16 1.58819e-22 C++ Note: df104 0.47875 -15.4978 C++ Note: df105 -1 -4.33333 C++ Note: df106 -5.60604e+17 3.61745e+23 C++ Note: df100 41542 4 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: values checked 0.431875 -15.4494 C++ Note: sums checked 8439.58 0.00124914 C++ Note: derivs checked 5815.58 0.00124914 C++ Note: second derivs checked 5815.58 0.00124914 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 8439.58 0.00124914 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 8439.58 0.00124914 C++ Note: risk checked 8439.58 C++ Note: risk1 checked 5815.58 0.00164722 C++ Note: risk2 checked 5815.58 0.00164722 C++ Note: riskr checked 1135 1269.08 C++ Note: riskl checked 53 50.8247 C++ Note: df101 -248.958 -248.958 C++ Note: df102 0 -3.97047e-22 C++ Note: df103 0 -3.97047e-22 C++ Note: df104 0.431875 -15.4494 C++ Note: df105 nan 1 C++ Note: df106 -inf 6.27025e+23 C++ Note: df100 44094 5 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Changing back to best C++ Note: values checked 0.385 -15.4009 C++ Note: sums checked 8173.26 0.0013112 C++ Note: derivs checked 5549.26 0.0013112 C++ Note: second derivs checked 5549.26 0.0013112 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 8173.26 0.0013112 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 8173.26 0.0013112 C++ Note: risk checked 8173.27 C++ Note: risk1 checked 5549.27 0.0016745 C++ Note: risk2 checked 5549.27 0.0016745 C++ Note: riskr checked 1135 1210.96 C++ Note: riskl checked 53 48.4973 C++ Note: df101 -248.958 -248.958 C++ Note: df102 3.33067e-16 -2.30287e-21 C++ Note: df103 -3.33067e-16 -2.30287e-21 C++ Note: df104 0.385 -15.4009 C++ Note: df105 -1 1 C++ Note: df106 -7.47472e+17 1.08108e+23 C++ Note: Starting Halves C++ Note: df501 -248.9581 C++ Note: df504 0.3850002 -15.40086 C++ Note: values checked 0.41625 -15.4321 C++ Note: sums checked 8349.42 0.00127086 C++ Note: derivs checked 5725.42 0.00127086 C++ Note: second derivs checked 5725.42 0.00127086 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 8349.42 0.00127086 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 8349.42 0.00127086 C++ Note: risk checked 8349.42 C++ Note: risk1 checked 5725.42 0.00165796 C++ Note: risk2 checked 5725.42 0.00165796 C++ Note: riskr checked 1135 1249.4 C++ Note: riskl checked 53 50.0368 C++ Note: df101 -248.958 -248.958 C++ Note: df102 6.66134e-16 2.62051e-21 C++ Note: df103 -6.66134e-16 3.12343e-21 C++ Note: df104 0.41625 -15.4321 C++ Note: df105 -1 0.838983 C++ Note: df106 -3.73736e+17 -9.50037e+22 C++ Note: df100 49201 1 2 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: values checked 0.400625 -15.4165 C++ Note: sums checked 8260.65 0.00129088 C++ Note: derivs checked 5636.65 0.00129088 C++ Note: second derivs checked 5636.65 0.00129088 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 8260.65 0.00129088 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 8260.65 0.00129088 C++ Note: risk checked 8260.65 C++ Note: risk1 checked 5636.65 0.00166617 C++ Note: risk2 checked 5636.65 0.00166617 C++ Note: riskr checked 1135 1230.03 C++ Note: riskl checked 53 49.261 C++ Note: df101 -248.958 -248.958 C++ Note: df102 -2.33147e-15 -5.29396e-22 C++ Note: df103 5.55112e-15 -9.79382e-22 C++ Note: df104 0.400625 -15.4165 C++ Note: df105 -0.42 0.540541 C++ Note: df106 1.06782e+17 4.70269e+23 C++ Note: df100 51737 2 2 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: values checked 0.392813 -15.4087 C++ Note: sums checked 8216.79 0.001301 C++ Note: derivs checked 5592.79 0.001301 C++ Note: second derivs checked 5592.79 0.001301 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 8216.79 0.001301 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 8216.79 0.001301 C++ Note: risk checked 8216.79 C++ Note: risk1 checked 5592.79 0.00167032 C++ Note: risk2 checked 5592.79 0.00167032 C++ Note: riskr checked 1135 1220.46 C++ Note: riskl checked 53 48.8777 C++ Note: df101 -248.958 -248.958 C++ Note: df102 1.11022e-16 2.24993e-21 C++ Note: df103 -1.11022e-16 1.48231e-21 C++ Note: df104 0.392813 -15.4087 C++ Note: df105 -1 1.51786 C++ Note: df106 -2.24241e+18 -1.10651e+23 C++ Note: df100 54346 3 2 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: values checked 0.388906 -15.4048 C++ Note: sums checked 8194.98 0.00130609 C++ Note: derivs checked 5570.98 0.00130609 C++ Note: second derivs checked 5570.98 0.00130609 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 8194.98 0.00130609 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 8194.98 0.00130609 C++ Note: risk checked 8194.99 C++ Note: risk1 checked 5570.99 0.00167241 C++ Note: risk2 checked 5570.99 0.00167241 C++ Note: riskr checked 1135 1215.7 C++ Note: riskl checked 53 48.6871 C++ Note: df101 -248.958 -248.958 C++ Note: df102 1.66533e-15 -3.97047e-22 C++ Note: df103 -3.21965e-15 -3.97047e-22 C++ Note: df104 0.388906 -15.4048 C++ Note: df105 -0.517241 1 C++ Note: df106 -1.49494e+17 6.27025e+23 C++ Note: df100 56881 4 2 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: values checked 0.386953 -15.4028 C++ Note: sums checked 8184.11 0.00130865 C++ Note: derivs checked 5560.11 0.00130865 C++ Note: second derivs checked 5560.11 0.00130865 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 8184.11 0.00130865 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 8184.11 0.00130865 C++ Note: risk checked 8184.12 C++ Note: risk1 checked 5560.11 0.00167345 C++ Note: risk2 checked 5560.11 0.00167345 C++ Note: riskr checked 1135 1213.33 C++ Note: riskl checked 53 48.5921 C++ Note: df101 -248.958 -248.958 C++ Note: df102 3.33067e-16 -7.94093e-22 C++ Note: df103 -3.33067e-16 -7.94093e-22 C++ Note: df104 0.386953 -15.4028 C++ Note: df105 -1 1 C++ Note: df106 -7.47472e+17 3.13512e+23 C++ Note: df100 59422 5 2 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Changing back to best C++ Note: values checked 0.385 -15.4009 C++ Note: sums checked 8173.26 0.0013112 C++ Note: derivs checked 5549.26 0.0013112 C++ Note: second derivs checked 5549.26 0.0013112 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 8173.26 0.0013112 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 8173.26 0.0013112 C++ Note: risk checked 8173.27 C++ Note: risk1 checked 5549.27 0.0016745 C++ Note: risk2 checked 5549.27 0.0016745 C++ Note: riskr checked 1135 1210.96 C++ Note: riskl checked 53 48.4973 C++ Note: df101 -248.958 -248.958 C++ Note: df102 3.33067e-16 -2.30287e-21 C++ Note: df103 -3.33067e-16 -2.30287e-21 C++ Note: df104 0.385 -15.4009 C++ Note: df105 -1 1 C++ Note: df106 -7.47472e+17 1.08108e+23 C++ Note: Starting Halves C++ Note: df501 -248.9581 C++ Note: df504 0.3850002 -15.40086 C++ Note: values checked 0.385977 -15.4018 C++ Note: sums checked 8178.69 0.00130993 C++ Note: derivs checked 5554.69 0.00130993 C++ Note: second derivs checked 5554.69 0.00130993 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 8178.69 0.00130993 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 8178.69 0.00130993 C++ Note: risk checked 8178.69 C++ Note: risk1 checked 5554.69 0.00167398 C++ Note: risk2 checked 5554.69 0.00167398 C++ Note: riskr checked 1135 1212.15 C++ Note: riskl checked 53 48.5447 C++ Note: df101 -248.958 -248.958 C++ Note: df102 4.44089e-16 1.08526e-21 C++ Note: df103 -4.44089e-16 1.08526e-21 C++ Note: df104 0.385977 -15.4018 C++ Note: df105 -1 1 C++ Note: df106 -5.60604e+17 -2.29399e+23 C++ Note: df100 64547 1 3 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: values checked 0.385488 -15.4014 C++ Note: sums checked 8175.98 0.00131056 C++ Note: derivs checked 5551.98 0.00131056 C++ Note: second derivs checked 5551.98 0.00131056 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 8175.98 0.00131056 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 8175.98 0.00131056 C++ Note: risk checked 8175.98 C++ Note: risk1 checked 5551.98 0.00167424 C++ Note: risk2 checked 5551.98 0.00167424 C++ Note: riskr checked 1135 1211.55 C++ Note: riskl checked 53 48.521 C++ Note: df101 -248.958 -248.958 C++ Note: df102 3.33067e-16 -5.29396e-22 C++ Note: df103 -3.33067e-16 -5.29396e-22 C++ Note: df104 0.385488 -15.4014 C++ Note: df105 -1 1 C++ Note: df106 -7.47472e+17 4.70269e+23 C++ Note: df100 67079 2 3 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: values checked 0.385244 -15.4011 C++ Note: sums checked 8174.62 0.00131088 C++ Note: derivs checked 5550.62 0.00131088 C++ Note: second derivs checked 5550.62 0.00131088 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 8174.62 0.00131088 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 8174.62 0.00131088 C++ Note: risk checked 8174.62 C++ Note: risk1 checked 5550.62 0.00167437 C++ Note: risk2 checked 5550.62 0.00167437 C++ Note: riskr checked 1135 1211.26 C++ Note: riskl checked 53 48.5091 C++ Note: df101 -248.958 -248.958 C++ Note: df102 1.11022e-16 1.87935e-21 C++ Note: df103 -1.11022e-16 1.87935e-21 C++ Note: df104 0.385244 -15.4011 C++ Note: df105 -1 1 C++ Note: df106 -2.24241e+18 -1.3247e+23 C++ Note: df100 69618 3 3 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: values checked 0.385122 -15.401 C++ Note: sums checked 8173.94 0.00131104 C++ Note: derivs checked 5549.94 0.00131104 C++ Note: second derivs checked 5549.94 0.00131104 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 8173.94 0.00131104 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 8173.94 0.00131104 C++ Note: risk checked 8173.94 C++ Note: risk1 checked 5549.94 0.00167444 C++ Note: risk2 checked 5549.94 0.00167444 C++ Note: riskr checked 1135 1211.11 C++ Note: riskl checked 53 48.5032 C++ Note: df101 -248.958 -248.958 C++ Note: df102 5.55112e-16 -1.00585e-21 C++ Note: df103 -5.55112e-16 -5.29396e-22 C++ Note: df104 0.385122 -15.401 C++ Note: df105 -1 1.9 C++ Note: df106 -4.48483e+17 2.4751e+23 C++ Note: df100 72153 4 3 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: values checked 0.385061 -15.4009 C++ Note: sums checked 8173.6 0.00131112 C++ Note: derivs checked 5549.6 0.00131112 C++ Note: second derivs checked 5549.6 0.00131112 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 8173.6 0.00131112 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 8173.6 0.00131112 C++ Note: risk checked 8173.61 C++ Note: risk1 checked 5549.6 0.00167447 C++ Note: risk2 checked 5549.6 0.00167447 C++ Note: riskr checked 1135 1211.04 C++ Note: riskl checked 53 48.5003 C++ Note: df101 -248.958 -248.958 C++ Note: df102 4.21885e-15 -1.34996e-21 C++ Note: df103 -8.21565e-15 -1.34996e-21 C++ Note: df104 0.385061 -15.4009 C++ Note: df105 -0.513514 1 C++ Note: df106 -5.90109e+16 1.84419e+23 C++ Note: df100 74687 5 3 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Changing back to best C++ Note: values checked 0.385 -15.4009 C++ Note: sums checked 8173.26 0.0013112 C++ Note: derivs checked 5549.26 0.0013112 C++ Note: second derivs checked 5549.26 0.0013112 C++ Note: dose checked 6400 6400 C++ Note: non-dose checked 8173.26 0.0013112 C++ Note: LIN_non-dose checked 6400 6400 C++ Note: PLIN_non-dose checked 6400 6400 C++ Note: LOGLIN_non-dose checked 8173.26 0.0013112 C++ Note: risk checked 8173.27 C++ Note: risk1 checked 5549.27 0.0016745 C++ Note: risk2 checked 5549.27 0.0016745 C++ Note: riskr checked 1135 1210.96 C++ Note: riskl checked 53 48.4973 C++ Note: df101 -248.958 -248.958 C++ Note: df102 3.33067e-16 -2.30287e-21 C++ Note: df103 -3.33067e-16 -2.30287e-21 C++ Note: df104 0.385 -15.4009 C++ Note: df105 -1 1 C++ Note: df106 -7.47472e+17 1.08108e+23 C++ Note: riskr checked 1135 1210.96 C++ Note: riskl checked 53 48.4973 C++ Note: df101 -248.958 -248.958 C++ Note: df102 3.33067e-16 -2.30287e-21 C++ Note: df103 -3.33067e-16 -2.30287e-21 C++ Note: df104 0.385 -15.4009 C++ Note: df105 -1 1 C++ Note: df106 -7.47472e+17 1.08108e+23 C++ Note: Exiting Regression C++ Note: df501 -248.9581 C++ Note: df504 0.3850002 -15.40086 Error: Atleast one parameter must be free Error: no events Error: Default Parameters used: 4, Covariates used: 6 Warning: rmin and rmax lists not equal size, defaulting to lin and loglin min/max values C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,32,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 1 C++ Note: values checked -0.1 6 0.1 0.1 C++ Note: sums checked 254.8 254.8 8.4 8.4 C++ Note: dose checked 7 C++ Note: non-dose checked 338.8 C++ Note: LIN_non-dose checked 8.4 C++ Note: PLIN_non-dose checked 254.8 C++ Note: LOGLIN_non-dose checked 7 C++ Note: df99,234,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:17 2024 Note: 1 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,31,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 1 C++ Note: values checked 0.2215742 6.617788 0.7390184 0.9740044 C++ Note: sums checked 294.2532 294.2532 71.94696 71.94696 C++ Note: dose checked 7 C++ Note: non-dose checked 3352.422 C++ Note: LIN_non-dose checked 71.94696 C++ Note: PLIN_non-dose checked 294.2532 C++ Note: LOGLIN_non-dose checked 7 C++ Note: df99,222,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:17 2024 Note: 2 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,31,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 1 C++ Note: values checked 0.5654312 6.279162 0.3661973 1.023089 C++ Note: sums checked 294.4729 294.4729 58.35 58.35 C++ Note: dose checked 7 C++ Note: non-dose checked 2720.897 C++ Note: LIN_non-dose checked 58.35 C++ Note: PLIN_non-dose checked 294.4729 C++ Note: LOGLIN_non-dose checked 7 C++ Note: df99,220,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:17 2024 Note: 3 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,31,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 1 C++ Note: values checked 0.4540596 6.915258 0.7989374 1.006046 C++ Note: sums checked 316.5113 316.5113 75.80929 75.80929 C++ Note: dose checked 7 C++ Note: non-dose checked 3800.228 C++ Note: LIN_non-dose checked 75.80929 C++ Note: PLIN_non-dose checked 316.5113 C++ Note: LOGLIN_non-dose checked 7 C++ Note: df99,224,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:17 2024 Note: 4 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,31,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 1 C++ Note: values checked 0.005602757 6.392582 0.9584111 0.8517844 C++ Note: sums checked 275.7237 275.7237 76.02821 76.02821 C++ Note: dose checked 7 C++ Note: non-dose checked 3318.978 C++ Note: LIN_non-dose checked 76.02821 C++ Note: PLIN_non-dose checked 275.7237 C++ Note: LOGLIN_non-dose checked 7 C++ Note: df99,292,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:17 2024 Note: 5 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,32,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 1 C++ Note: values checked 0.4204453 6.836265 0.9252424 0.4260211 C++ Note: sums checked 311.7818 311.7818 56.75307 56.75307 C++ Note: dose checked 7 C++ Note: non-dose checked 2802.357 C++ Note: LIN_non-dose checked 56.75307 C++ Note: PLIN_non-dose checked 311.7818 C++ Note: LOGLIN_non-dose checked 7 C++ Note: df99,229,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:17 2024 Note: 6 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,31,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 1 C++ Note: values checked 0.05800769 6.850922 0.6988397 0.5647598 C++ Note: sums checked 297.175 297.175 53.07118 53.07118 C++ Note: dose checked 7 C++ Note: non-dose checked 2497.505 C++ Note: LIN_non-dose checked 53.07118 C++ Note: PLIN_non-dose checked 297.175 C++ Note: LOGLIN_non-dose checked 7 C++ Note: df99,221,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:17 2024 Note: 7 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,30,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 1 C++ Note: values checked 0.5803103 6.831288 0.469853 0.5463882 C++ Note: sums checked 318.2871 318.2871 42.68213 42.68213 C++ Note: dose checked 7 C++ Note: non-dose checked 2151.634 C++ Note: LIN_non-dose checked 42.68213 C++ Note: PLIN_non-dose checked 318.2871 C++ Note: LOGLIN_non-dose checked 7 C++ Note: df99,217,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:17 2024 Note: 8 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,30,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 1 C++ Note: values checked 0.004723529 6.147166 1.021718 0.6426009 C++ Note: sums checked 265.3794 265.3794 69.9014 69.9014 C++ Note: dose checked 7 C++ Note: non-dose checked 2936.739 C++ Note: LIN_non-dose checked 69.9014 C++ Note: PLIN_non-dose checked 265.3794 C++ Note: LOGLIN_non-dose checked 7 C++ Note: df99,225,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:17 2024 Note: 9 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,31,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 1 C++ Note: values checked 0.569784 6.401194 1.070144 0.3297178 C++ Note: sums checked 299.7811 299.7811 58.7942 58.7942 C++ Note: dose checked 7 C++ Note: non-dose checked 2791.148 C++ Note: LIN_non-dose checked 58.7942 C++ Note: PLIN_non-dose checked 299.7811 C++ Note: LOGLIN_non-dose checked 7 C++ Note: df99,221,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:17 2024 Error: tform not implemented Not Warning: rmin and rmax lists not equal size, defaulting to lin and loglin min/max values C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,38,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 1 C++ Note: values checked -0.1 6 0.1 0.1 C++ Note: sums checked 6.978181e+23 6.978181e+23 6.978181e+23 6.978181e+23 C++ Note: dose checked 7 C++ Note: non-dose checked 6.978181e+23 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 6.978181e+23 C++ Note: df99,235,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:17 2024 Note: 1 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,31,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 1 C++ Note: values checked -1.078912 6.381868 -0.6204552 0.1403137 C++ Note: sums checked 7.148279e+18 7.148279e+18 7.148279e+18 7.148279e+18 C++ Note: dose checked 7 C++ Note: non-dose checked 7.148279e+18 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 7.148279e+18 C++ Note: df99,223,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:17 2024 Note: 2 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,32,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 1 C++ Note: values checked 0.124094 5.233358 0.7481482 0.8674378 C++ Note: sums checked 1.801258e+27 1.801258e+27 1.801258e+27 1.801258e+27 C++ Note: dose checked 7 C++ Note: non-dose checked 1.801258e+27 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 1.801258e+27 C++ Note: df99,221,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:17 2024 Note: 3 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,32,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 1 C++ Note: values checked 0.723155 5.889726 0.2044639 -0.4021117 C++ Note: sums checked 1.190181e+25 1.190181e+25 1.190181e+25 1.190181e+25 C++ Note: dose checked 7 C++ Note: non-dose checked 1.190181e+25 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 1.190181e+25 C++ Note: df99,213,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:17 2024 Note: 4 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,30,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 1 C++ Note: values checked -0.9384565 5.491963 -0.4929961 0.02297141 C++ Note: sums checked 9.295681e+15 9.295681e+15 9.295681e+15 9.295681e+15 C++ Note: dose checked 7 C++ Note: non-dose checked 9.295681e+15 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 9.295681e+15 C++ Note: df99,217,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:17 2024 Note: 5 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,30,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 1 C++ Note: values checked 0.7582357 5.622153 0.1475021 -0.6665197 C++ Note: sums checked 8.152489e+22 8.152489e+22 8.152489e+22 8.152489e+22 C++ Note: dose checked 7 C++ Note: non-dose checked 8.152489e+22 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 8.152489e+22 C++ Note: df99,220,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:17 2024 Note: 6 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,31,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 1 C++ Note: values checked -0.3285743 6.883413 -0.7341383 -0.6765644 C++ Note: sums checked 1.285792e+20 1.285792e+20 1.285792e+20 1.285792e+20 C++ Note: dose checked 7 C++ Note: non-dose checked 1.285792e+20 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 1.285792e+20 C++ Note: df99,221,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:17 2024 Note: 7 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,31,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 1 C++ Note: values checked -0.3835654 5.580549 0.8623136 0.6676176 C++ Note: sums checked 1.966433e+26 1.966433e+26 1.966433e+26 1.966433e+26 C++ Note: dose checked 7 C++ Note: non-dose checked 1.966433e+26 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 1.966433e+26 C++ Note: df99,218,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:17 2024 Note: 8 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,31,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 1 C++ Note: values checked 0.5220103 6.580932 0.07026672 0.2925053 C++ Note: sums checked 1.517451e+29 1.517451e+29 1.517451e+29 1.517451e+29 C++ Note: dose checked 7 C++ Note: non-dose checked 1.517451e+29 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 1.517451e+29 C++ Note: df99,220,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:17 2024 Note: 9 valid guesses C++ Note: START_RISK_CHECK C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 0 0 0 C++ Note: df99,31,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 1 C++ Note: values checked -0.7559232 5.684553 -0.3870322 -0.194844 C++ Note: sums checked 9.899231e+16 9.899231e+16 9.899231e+16 9.899231e+16 C++ Note: dose checked 7 C++ Note: non-dose checked 9.899231e+16 C++ Note: LIN_non-dose checked 7 C++ Note: PLIN_non-dose checked 7 C++ Note: LOGLIN_non-dose checked 9.899231e+16 C++ Note: df99,219,Prep_Terms C++ Note: Current Time, Tue Feb 13 22:47:17 2024 Error: verbosity arguement not valid Error: verbosity arguement not valid Error: a0 arguement was not a number Error: a0 arguement was not a number Error: a0 arguement was not a number Error: item e1 in name_list has 1 items, but same item in Term_n_list has 6 items. Omit entry in Term_n_list to set to default of term 0 or add missing values Error: item e1 in name_list has 1 items, but same item in tform_list has 6 items. Omit entry in tform_list to set to default of 'loglin' or add missing values Error: item e1 in name_list has 1 items, but same item in keep_constant_list has 6 items. Omit entry in tform_list to set to default of 0 or add missing values Error: item e1 in name_list has 1 items, but same item in a_n_list has 6 items. Omit entry in a_n_list to set to default of 0 or add missing values Note: 2 strata used Note: 114 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Grouping Start C++ Note: df100 839 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: riskr checked 3237 C++ Note: riskl checked 59 Note: 2 strata used Note: 114 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 C++ Note: df99,22,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Grouping Start C++ Note: df100 859 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked 0.01 C++ Note: sums checked 1016.5 C++ Note: risk checked 1016.5 C++ Note: risk1 checked 1673.67 C++ Note: risk2 checked 4753.83 C++ Note: Made Risk Side Lists C++ Note: riskr checked 3284.26 2905.4 C++ Note: riskl checked 60.0534 56.1054 C++ Note: df101 -447.464 C++ Note: df104 0.01 C++ Note: Starting Halves C++ Note: df501 -447.4645 C++ Note: df504 0.01 C++ Note: values checked 0.01 C++ Note: sums checked 1016.5 C++ Note: risk checked 1016.5 C++ Note: risk1 checked 1673.67 C++ Note: risk2 checked 4753.83 C++ Note: riskr checked 3284.26 2905.4 C++ Note: riskl checked 60.0534 56.1054 C++ Note: df101 -447.464 C++ Note: df104 0.01 C++ Note: df100 2139 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: riskr checked 3284.26 2905.4 C++ Note: riskl checked 60.0534 56.1054 C++ Note: df101 -447.464 C++ Note: df104 0.01 C++ Note: ending guess 0 C++ Note: df501 -447.4645 C++ Note: df504 0.01 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.01, -447.4645<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0.01 C++ Note: sums checked 1016.5 C++ Note: risk checked 1016.5 C++ Note: risk1 checked 1673.67 C++ Note: risk2 checked 4753.83 C++ Note: Made Risk Side Lists C++ Note: riskr checked 3284.26 2905.4 C++ Note: riskl checked 60.0534 56.1054 C++ Note: df101 -447.464 C++ Note: df104 0.01 C++ Note: Starting Halves C++ Note: df501 -447.4645 C++ Note: df504 0.01 C++ Note: values checked 0.01 C++ Note: sums checked 1016.5 C++ Note: risk checked 1016.5 C++ Note: risk1 checked 1673.67 C++ Note: risk2 checked 4753.83 C++ Note: riskr checked 3284.26 2905.4 C++ Note: riskl checked 60.0534 56.1054 C++ Note: df101 -447.464 C++ Note: df104 0.01 C++ Note: df100 3886 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: riskr checked 3284.26 2905.4 C++ Note: riskl checked 60.0534 56.1054 C++ Note: df101 -447.464 C++ Note: df104 0.01 C++ Note: riskr checked 3284.26 2905.4 C++ Note: riskl checked 60.0534 56.1054 C++ Note: df101 -447.464 C++ Note: df104 0.01 C++ Note: Exiting Regression C++ Note: df501 -447.4645 C++ Note: df504 0.01 Note: 2 strata used Note: 114 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Grouping Start C++ Note: df100 784 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: riskr checked 3237 C++ Note: riskl checked 59 Note: 2 strata used Note: 114 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Term checked 0 C++ Note: df99,22,Starting C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Grouping Start C++ Note: df100 813 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked 0.01 C++ Note: sums checked 1016.5 C++ Note: risk checked 1016.5 C++ Note: risk1 checked 1673.67 C++ Note: risk2 checked 4753.83 C++ Note: Made Risk Side Lists C++ Note: riskr checked 3284.26 2905.4 C++ Note: riskl checked 60.0534 56.1054 C++ Note: df101 -447.464 C++ Note: df102 -4.51629 C++ Note: df103 -38.8061 C++ Note: df104 0.01 C++ Note: df105 0.116381 C++ Note: df106 99.0778 C++ Note: Starting Halves C++ Note: df501 -447.4645 C++ Note: df504 0.01 C++ Note: values checked -0.0772857 C++ Note: sums checked 886.858 C++ Note: risk checked 886.858 C++ Note: risk1 checked 1314.48 C++ Note: risk2 checked 3543.11 C++ Note: riskr checked 2906.58 2520.49 C++ Note: riskl checked 51.6944 47.43 C++ Note: df101 -447.218 C++ Note: df102 -1.11664 C++ Note: df103 -39.0819 C++ Note: df104 -0.0772857 C++ Note: df105 0.0285718 C++ Note: df106 400.504 C++ Note: df100 3513 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: riskr checked 2906.58 2520.49 C++ Note: riskl checked 51.6944 47.43 C++ Note: df101 -447.218 C++ Note: df102 -1.11664 C++ Note: df103 -39.0819 C++ Note: df104 -0.0772857 C++ Note: df105 0.0285718 C++ Note: df106 400.504 C++ Note: ending guess 0 C++ Note: df501 -447.2185 C++ Note: df504 -0.07728569 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.07728569, -447.2185<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.0772857 C++ Note: sums checked 886.858 C++ Note: risk checked 886.858 C++ Note: risk1 checked 1314.48 C++ Note: risk2 checked 3543.11 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2906.58 2520.49 C++ Note: riskl checked 51.6944 47.43 C++ Note: df101 -447.218 C++ Note: df102 -1.11664 C++ Note: df103 -39.0819 C++ Note: df104 -0.0772857 C++ Note: df105 0.0285718 C++ Note: df106 400.504 C++ Note: Starting Halves C++ Note: df501 -447.2185 C++ Note: df504 -0.07728569 C++ Note: values checked -0.0987146 C++ Note: sums checked 859.484 C++ Note: risk checked 859.484 C++ Note: risk1 checked 1241.17 C++ Note: risk2 checked 3301.92 C++ Note: riskr checked 2824.77 2437.74 C++ Note: riskl checked 49.9037 45.6007 C++ Note: df101 -447.204 C++ Note: df102 -0.27852 C++ Note: df103 -39.141 C++ Note: df104 -0.0987146 C++ Note: df105 0.00711582 C++ Note: df106 1605.64 C++ Note: df100 7460 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: riskr checked 2824.77 2437.74 C++ Note: riskl checked 49.9037 45.6007 C++ Note: df101 -447.204 C++ Note: df102 -0.27852 C++ Note: df103 -39.141 C++ Note: df104 -0.0987146 C++ Note: df105 0.00711582 C++ Note: df106 1605.64 C++ Note: riskr checked 2824.77 2437.74 C++ Note: riskl checked 49.9037 45.6007 C++ Note: df101 -447.204 C++ Note: df102 -0.27852 C++ Note: df103 -39.141 C++ Note: df104 -0.0987146 C++ Note: df105 0.00711582 C++ Note: df106 1605.64 C++ Note: Exiting Regression C++ Note: df501 -447.2035 C++ Note: df504 -0.09871455 Note: 2 strata used Note: 114 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: Grouping Start C++ Note: df100 779 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:17 2024 C++ Note: riskr checked 3237 C++ Note: riskl checked 59 Note: 2 strata used Note: 114 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 C++ Note: df99,21,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 812 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked 0.01 C++ Note: sums checked 1016.5 C++ Note: dose checked 1000 C++ Note: non-dose checked 1016.5 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 1016.5 C++ Note: risk checked 1016.5 C++ Note: Made Risk Side Lists C++ Note: riskr checked 3284.26 2905.4 C++ Note: riskl checked 60.0534 56.1054 C++ Note: df101 -447.464 C++ Note: df104 0.01 C++ Note: Starting Halves C++ Note: df501 -447.4645 C++ Note: df504 0.01 C++ Note: values checked 0.01 C++ Note: sums checked 1016.5 C++ Note: dose checked 1000 C++ Note: non-dose checked 1016.5 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 1016.5 C++ Note: risk checked 1016.5 C++ Note: riskr checked 3284.26 2905.4 C++ Note: riskl checked 60.0534 56.1054 C++ Note: df101 -447.464 C++ Note: df104 0.01 C++ Note: df100 2228 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 3284.26 2905.4 C++ Note: riskl checked 60.0534 56.1054 C++ Note: df101 -447.464 C++ Note: df104 0.01 C++ Note: ending guess 0 C++ Note: df501 -447.4645 C++ Note: df504 0.01 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.01, -447.4645<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0.01 C++ Note: sums checked 1016.5 C++ Note: dose checked 1000 C++ Note: non-dose checked 1016.5 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 1016.5 C++ Note: risk checked 1016.5 C++ Note: Made Risk Side Lists C++ Note: riskr checked 3284.26 2905.4 C++ Note: riskl checked 60.0534 56.1054 C++ Note: df101 -447.464 C++ Note: df104 0.01 C++ Note: Starting Halves C++ Note: df501 -447.4645 C++ Note: df504 0.01 C++ Note: values checked 0.01 C++ Note: sums checked 1016.5 C++ Note: dose checked 1000 C++ Note: non-dose checked 1016.5 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 1016.5 C++ Note: risk checked 1016.5 C++ Note: riskr checked 3284.26 2905.4 C++ Note: riskl checked 60.0534 56.1054 C++ Note: df101 -447.464 C++ Note: df104 0.01 C++ Note: df100 4069 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 3284.26 2905.4 C++ Note: riskl checked 60.0534 56.1054 C++ Note: df101 -447.464 C++ Note: df104 0.01 C++ Note: riskr checked 3284.26 2905.4 C++ Note: riskl checked 60.0534 56.1054 C++ Note: df101 -447.464 C++ Note: df104 0.01 C++ Note: Exiting Regression C++ Note: df501 -447.4645 C++ Note: df504 0.01 Note: 2 strata used Note: 114 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 784 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 3237 C++ Note: riskl checked 59 Note: 2 strata used Note: 114 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 C++ Note: df99,22,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 811 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked 0.01 C++ Note: sums checked 1016.5 C++ Note: derivs checked 1673.67 C++ Note: second derivs checked 4753.83 C++ Note: dose checked 1000 C++ Note: non-dose checked 1016.5 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 1016.5 C++ Note: risk checked 1016.5 C++ Note: risk1 checked 1673.67 C++ Note: risk2 checked 4753.83 C++ Note: Made Risk Side Lists C++ Note: riskr checked 3284.26 2905.4 C++ Note: riskl checked 60.0534 56.1054 C++ Note: df101 -447.464 C++ Note: df102 -4.51629 C++ Note: df103 -38.8061 C++ Note: df104 0.01 C++ Note: df105 0.116381 C++ Note: df106 99.0778 C++ Note: Starting Halves C++ Note: df501 -447.4645 C++ Note: df504 0.01 C++ Note: values checked -0.0772857 C++ Note: sums checked 886.858 C++ Note: derivs checked 1314.48 C++ Note: second derivs checked 3543.11 C++ Note: dose checked 1000 C++ Note: non-dose checked 886.858 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 886.858 C++ Note: risk checked 886.858 C++ Note: risk1 checked 1314.48 C++ Note: risk2 checked 3543.11 C++ Note: riskr checked 2906.58 2520.49 C++ Note: riskl checked 51.6944 47.43 C++ Note: df101 -447.218 C++ Note: df102 -1.11664 C++ Note: df103 -39.0819 C++ Note: df104 -0.0772857 C++ Note: df105 0.0285718 C++ Note: df106 400.504 C++ Note: df100 3959 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 2906.58 2520.49 C++ Note: riskl checked 51.6944 47.43 C++ Note: df101 -447.218 C++ Note: df102 -1.11664 C++ Note: df103 -39.0819 C++ Note: df104 -0.0772857 C++ Note: df105 0.0285718 C++ Note: df106 400.504 C++ Note: ending guess 0 C++ Note: df501 -447.2185 C++ Note: df504 -0.07728569 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.07728569, -447.2185<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.0772857 C++ Note: sums checked 886.858 C++ Note: derivs checked 1314.48 C++ Note: second derivs checked 3543.11 C++ Note: dose checked 1000 C++ Note: non-dose checked 886.858 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 886.858 C++ Note: risk checked 886.858 C++ Note: risk1 checked 1314.48 C++ Note: risk2 checked 3543.11 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2906.58 2520.49 C++ Note: riskl checked 51.6944 47.43 C++ Note: df101 -447.218 C++ Note: df102 -1.11664 C++ Note: df103 -39.0819 C++ Note: df104 -0.0772857 C++ Note: df105 0.0285718 C++ Note: df106 400.504 C++ Note: Starting Halves C++ Note: df501 -447.2185 C++ Note: df504 -0.07728569 C++ Note: values checked -0.0987146 C++ Note: sums checked 859.484 C++ Note: derivs checked 1241.17 C++ Note: second derivs checked 3301.92 C++ Note: dose checked 1000 C++ Note: non-dose checked 859.484 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 859.484 C++ Note: risk checked 859.484 C++ Note: risk1 checked 1241.17 C++ Note: risk2 checked 3301.92 C++ Note: riskr checked 2824.77 2437.74 C++ Note: riskl checked 49.9037 45.6007 C++ Note: df101 -447.204 C++ Note: df102 -0.27852 C++ Note: df103 -39.141 C++ Note: df104 -0.0987146 C++ Note: df105 0.00711582 C++ Note: df106 1605.64 C++ Note: df100 8260 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 2824.77 2437.74 C++ Note: riskl checked 49.9037 45.6007 C++ Note: df101 -447.204 C++ Note: df102 -0.27852 C++ Note: df103 -39.141 C++ Note: df104 -0.0987146 C++ Note: df105 0.00711582 C++ Note: df106 1605.64 C++ Note: riskr checked 2824.77 2437.74 C++ Note: riskl checked 49.9037 45.6007 C++ Note: df101 -447.204 C++ Note: df102 -0.27852 C++ Note: df103 -39.141 C++ Note: df104 -0.0987146 C++ Note: df105 0.00711582 C++ Note: df106 1605.64 C++ Note: Exiting Regression C++ Note: df501 -447.2035 C++ Note: df504 -0.09871455 Note: 114 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 442 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 12119 C++ Note: riskl checked 114 Note: 114 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 C++ Note: df99,21,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 459 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked 0.01 C++ Note: sums checked 1016.5 C++ Note: risk checked 1016.5 C++ Note: risk1 checked 1673.67 C++ Note: risk2 checked 4753.83 C++ Note: Made Risk Side Lists C++ Note: riskr checked 12309.1 C++ Note: riskl checked 116.159 C++ Note: df101 -525.819 C++ Note: df104 0.01 C++ Note: Starting Halves C++ Note: df501 -525.8191 C++ Note: df504 0.01 C++ Note: values checked 0.01 C++ Note: sums checked 1016.5 C++ Note: risk checked 1016.5 C++ Note: risk1 checked 1673.67 C++ Note: risk2 checked 4753.83 C++ Note: riskr checked 12309.1 C++ Note: riskl checked 116.159 C++ Note: df101 -525.819 C++ Note: df104 0.01 C++ Note: df100 1289 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 12309.1 C++ Note: riskl checked 116.159 C++ Note: df101 -525.819 C++ Note: df104 0.01 C++ Note: ending guess 0 C++ Note: df501 -525.8191 C++ Note: df504 0.01 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.01, -525.8191<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0.01 C++ Note: sums checked 1016.5 C++ Note: risk checked 1016.5 C++ Note: risk1 checked 1673.67 C++ Note: risk2 checked 4753.83 C++ Note: Made Risk Side Lists C++ Note: riskr checked 12309.1 C++ Note: riskl checked 116.159 C++ Note: df101 -525.819 C++ Note: df104 0.01 C++ Note: Starting Halves C++ Note: df501 -525.8191 C++ Note: df504 0.01 C++ Note: values checked 0.01 C++ Note: sums checked 1016.5 C++ Note: risk checked 1016.5 C++ Note: risk1 checked 1673.67 C++ Note: risk2 checked 4753.83 C++ Note: riskr checked 12309.1 C++ Note: riskl checked 116.159 C++ Note: df101 -525.819 C++ Note: df104 0.01 C++ Note: df100 2401 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 12309.1 C++ Note: riskl checked 116.159 C++ Note: df101 -525.819 C++ Note: df104 0.01 C++ Note: riskr checked 12309.1 C++ Note: riskl checked 116.159 C++ Note: df101 -525.819 C++ Note: df104 0.01 C++ Note: Exiting Regression C++ Note: df501 -525.8191 C++ Note: df504 0.01 Note: 114 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 427 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 12119 C++ Note: riskl checked 114 Note: 114 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 C++ Note: df99,21,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 460 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked 0.01 C++ Note: sums checked 1016.5 C++ Note: risk checked 1016.5 C++ Note: risk1 checked 1673.67 C++ Note: risk2 checked 4753.83 C++ Note: Made Risk Side Lists C++ Note: riskr checked 12309.1 C++ Note: risk1r checked 19240.9 C++ Note: risk2r checked 46924.9 C++ Note: riskl checked 116.159 C++ Note: risk1l checked 218.829 C++ Note: risk2l checked 595.535 C++ Note: df101 -525.819 C++ Note: df102 -4.47019 C++ Note: df103 -39.2834 C++ Note: df104 0.01 C++ Note: df105 0.113793 C++ Note: df106 117.628 C++ Note: Starting Halves C++ Note: df501 -525.8191 C++ Note: df504 0.01 C++ Note: values checked -0.0753449 C++ Note: sums checked 889.415 C++ Note: risk checked 889.415 C++ Note: risk1 checked 1321.38 C++ Note: risk2 checked 3565.92 C++ Note: riskr checked 10823.9 C++ Note: risk1r checked 15714.3 C++ Note: risk2r checked 36253.4 C++ Note: riskl checked 99.4622 C++ Note: risk1l checked 174.499 C++ Note: risk2l checked 450.907 C++ Note: df101 -525.581 C++ Note: df102 -1.10144 C++ Note: df103 -39.6548 C++ Note: df104 -0.0753449 C++ Note: df105 0.0277758 C++ Note: df106 477.175 C++ Note: df100 2036 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 10823.9 C++ Note: risk1r checked 15714.3 C++ Note: risk2r checked 36253.4 C++ Note: riskl checked 99.4622 C++ Note: risk1l checked 174.499 C++ Note: risk2l checked 450.907 C++ Note: df101 -525.581 C++ Note: df102 -1.10144 C++ Note: df103 -39.6548 C++ Note: df104 -0.0753449 C++ Note: df105 0.0277758 C++ Note: df106 477.175 C++ Note: ending guess 0 C++ Note: df501 -525.5812 C++ Note: df504 -0.07534494 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.07534494, -525.5812<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.0753449 C++ Note: sums checked 889.415 C++ Note: risk checked 889.415 C++ Note: risk1 checked 1321.38 C++ Note: risk2 checked 3565.92 C++ Note: Made Risk Side Lists C++ Note: riskr checked 10823.9 C++ Note: risk1r checked 15714.3 C++ Note: risk2r checked 36253.4 C++ Note: riskl checked 99.4622 C++ Note: risk1l checked 174.499 C++ Note: risk2l checked 450.907 C++ Note: df101 -525.581 C++ Note: df102 -1.10144 C++ Note: df103 -39.6548 C++ Note: df104 -0.0753449 C++ Note: df105 0.0277758 C++ Note: df106 477.175 C++ Note: Starting Halves C++ Note: df501 -525.5812 C++ Note: df504 -0.07534494 C++ Note: values checked -0.0961768 C++ Note: sums checked 862.645 C++ Note: risk checked 862.645 C++ Note: risk1 checked 1249.59 C++ Note: risk2 checked 3329.49 C++ Note: riskr checked 10504.3 C++ Note: risk1r checked 14981.8 C++ Note: risk2r checked 34097.7 C++ Note: riskl checked 95.9227 C++ Note: risk1l checked 165.411 C++ Note: risk2l checked 421.981 C++ Note: df101 -525.567 C++ Note: df102 -0.274471 C++ Note: df103 -39.7399 C++ Note: df104 -0.0961768 C++ Note: df105 0.00690668 C++ Note: df106 1914.84 C++ Note: df100 4211 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 10504.3 C++ Note: risk1r checked 14981.8 C++ Note: risk2r checked 34097.7 C++ Note: riskl checked 95.9227 C++ Note: risk1l checked 165.411 C++ Note: risk2l checked 421.981 C++ Note: df101 -525.567 C++ Note: df102 -0.274471 C++ Note: df103 -39.7399 C++ Note: df104 -0.0961768 C++ Note: df105 0.00690668 C++ Note: df106 1914.84 C++ Note: riskr checked 10504.3 C++ Note: risk1r checked 14981.8 C++ Note: risk2r checked 34097.7 C++ Note: riskl checked 95.9227 C++ Note: risk1l checked 165.411 C++ Note: risk2l checked 421.981 C++ Note: df101 -525.567 C++ Note: df102 -0.274471 C++ Note: df103 -39.7399 C++ Note: df104 -0.0961768 C++ Note: df105 0.00690668 C++ Note: df106 1914.84 C++ Note: Exiting Regression C++ Note: df501 -525.5668 C++ Note: df504 -0.09617677 Note: 114 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 429 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 12119 C++ Note: riskl checked 114 Note: 114 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 C++ Note: df99,21,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 452 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked 0.01 C++ Note: sums checked 1016.5 C++ Note: dose checked 1000 C++ Note: non-dose checked 1016.5 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 1016.5 C++ Note: risk checked 1016.5 C++ Note: Made Risk Side Lists C++ Note: riskr checked 12309.1 C++ Note: riskl checked 116.159 C++ Note: df101 -525.819 C++ Note: df104 0.01 C++ Note: Starting Halves C++ Note: df501 -525.8191 C++ Note: df504 0.01 C++ Note: values checked 0.01 C++ Note: sums checked 1016.5 C++ Note: dose checked 1000 C++ Note: non-dose checked 1016.5 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 1016.5 C++ Note: risk checked 1016.5 C++ Note: riskr checked 12309.1 C++ Note: riskl checked 116.159 C++ Note: df101 -525.819 C++ Note: df104 0.01 C++ Note: df100 1383 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 12309.1 C++ Note: riskl checked 116.159 C++ Note: df101 -525.819 C++ Note: df104 0.01 C++ Note: ending guess 0 C++ Note: df501 -525.8191 C++ Note: df504 0.01 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.01, -525.8191<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0.01 C++ Note: sums checked 1016.5 C++ Note: dose checked 1000 C++ Note: non-dose checked 1016.5 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 1016.5 C++ Note: risk checked 1016.5 C++ Note: Made Risk Side Lists C++ Note: riskr checked 12309.1 C++ Note: riskl checked 116.159 C++ Note: df101 -525.819 C++ Note: df104 0.01 C++ Note: Starting Halves C++ Note: df501 -525.8191 C++ Note: df504 0.01 C++ Note: values checked 0.01 C++ Note: sums checked 1016.5 C++ Note: dose checked 1000 C++ Note: non-dose checked 1016.5 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 1016.5 C++ Note: risk checked 1016.5 C++ Note: riskr checked 12309.1 C++ Note: riskl checked 116.159 C++ Note: df101 -525.819 C++ Note: df104 0.01 C++ Note: df100 2569 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 12309.1 C++ Note: riskl checked 116.159 C++ Note: df101 -525.819 C++ Note: df104 0.01 C++ Note: riskr checked 12309.1 C++ Note: riskl checked 116.159 C++ Note: df101 -525.819 C++ Note: df104 0.01 C++ Note: Exiting Regression C++ Note: df501 -525.8191 C++ Note: df504 0.01 Note: 114 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 423 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 12119 C++ Note: riskl checked 114 Note: 114 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 C++ Note: df99,21,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 457 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked 0.01 C++ Note: sums checked 1016.5 C++ Note: derivs checked 1673.67 C++ Note: second derivs checked 4753.83 C++ Note: dose checked 1000 C++ Note: non-dose checked 1016.5 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 1016.5 C++ Note: risk checked 1016.5 C++ Note: risk1 checked 1673.67 C++ Note: risk2 checked 4753.83 C++ Note: Made Risk Side Lists C++ Note: riskr checked 12309.1 C++ Note: risk1r checked 19240.9 C++ Note: risk2r checked 46924.9 C++ Note: riskl checked 116.159 C++ Note: risk1l checked 218.829 C++ Note: risk2l checked 595.535 C++ Note: df101 -525.819 C++ Note: df102 -4.47019 C++ Note: df103 -39.2834 C++ Note: df104 0.01 C++ Note: df105 0.113793 C++ Note: df106 117.628 C++ Note: Starting Halves C++ Note: df501 -525.8191 C++ Note: df504 0.01 C++ Note: values checked -0.0753449 C++ Note: sums checked 889.415 C++ Note: derivs checked 1321.38 C++ Note: second derivs checked 3565.92 C++ Note: dose checked 1000 C++ Note: non-dose checked 889.415 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 889.415 C++ Note: risk checked 889.415 C++ Note: risk1 checked 1321.38 C++ Note: risk2 checked 3565.92 C++ Note: riskr checked 10823.9 C++ Note: risk1r checked 15714.3 C++ Note: risk2r checked 36253.4 C++ Note: riskl checked 99.4622 C++ Note: risk1l checked 174.499 C++ Note: risk2l checked 450.907 C++ Note: df101 -525.581 C++ Note: df102 -1.10144 C++ Note: df103 -39.6548 C++ Note: df104 -0.0753449 C++ Note: df105 0.0277758 C++ Note: df106 477.175 C++ Note: df100 2425 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 10823.9 C++ Note: risk1r checked 15714.3 C++ Note: risk2r checked 36253.4 C++ Note: riskl checked 99.4622 C++ Note: risk1l checked 174.499 C++ Note: risk2l checked 450.907 C++ Note: df101 -525.581 C++ Note: df102 -1.10144 C++ Note: df103 -39.6548 C++ Note: df104 -0.0753449 C++ Note: df105 0.0277758 C++ Note: df106 477.175 C++ Note: ending guess 0 C++ Note: df501 -525.5812 C++ Note: df504 -0.07534494 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.07534494, -525.5812<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.0753449 C++ Note: sums checked 889.415 C++ Note: derivs checked 1321.38 C++ Note: second derivs checked 3565.92 C++ Note: dose checked 1000 C++ Note: non-dose checked 889.415 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 889.415 C++ Note: risk checked 889.415 C++ Note: risk1 checked 1321.38 C++ Note: risk2 checked 3565.92 C++ Note: Made Risk Side Lists C++ Note: riskr checked 10823.9 C++ Note: risk1r checked 15714.3 C++ Note: risk2r checked 36253.4 C++ Note: riskl checked 99.4622 C++ Note: risk1l checked 174.499 C++ Note: risk2l checked 450.907 C++ Note: df101 -525.581 C++ Note: df102 -1.10144 C++ Note: df103 -39.6548 C++ Note: df104 -0.0753449 C++ Note: df105 0.0277758 C++ Note: df106 477.175 C++ Note: Starting Halves C++ Note: df501 -525.5812 C++ Note: df504 -0.07534494 C++ Note: values checked -0.0961768 C++ Note: sums checked 862.645 C++ Note: derivs checked 1249.59 C++ Note: second derivs checked 3329.49 C++ Note: dose checked 1000 C++ Note: non-dose checked 862.645 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 862.645 C++ Note: risk checked 862.645 C++ Note: risk1 checked 1249.59 C++ Note: risk2 checked 3329.49 C++ Note: riskr checked 10504.3 C++ Note: risk1r checked 14981.8 C++ Note: risk2r checked 34097.7 C++ Note: riskl checked 95.9227 C++ Note: risk1l checked 165.411 C++ Note: risk2l checked 421.981 C++ Note: df101 -525.567 C++ Note: df102 -0.274471 C++ Note: df103 -39.7399 C++ Note: df104 -0.0961768 C++ Note: df105 0.00690668 C++ Note: df106 1914.84 C++ Note: df100 5006 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 10504.3 C++ Note: risk1r checked 14981.8 C++ Note: risk2r checked 34097.7 C++ Note: riskl checked 95.9227 C++ Note: risk1l checked 165.411 C++ Note: risk2l checked 421.981 C++ Note: df101 -525.567 C++ Note: df102 -0.274471 C++ Note: df103 -39.7399 C++ Note: df104 -0.0961768 C++ Note: df105 0.00690668 C++ Note: df106 1914.84 C++ Note: riskr checked 10504.3 C++ Note: risk1r checked 14981.8 C++ Note: risk2r checked 34097.7 C++ Note: riskl checked 95.9227 C++ Note: risk1l checked 165.411 C++ Note: risk2l checked 421.981 C++ Note: df101 -525.567 C++ Note: df102 -0.274471 C++ Note: df103 -39.7399 C++ Note: df104 -0.0961768 C++ Note: df105 0.00690668 C++ Note: df106 1914.84 C++ Note: Exiting Regression C++ Note: df501 -525.5668 C++ Note: df504 -0.09617677 Note: 114 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 C++ Note: df99,21,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 467 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked 0 C++ Note: sums checked 1000 C++ Note: derivs checked 1626.94 C++ Note: second derivs checked 4593.87 C++ Note: dose checked 1000 C++ Note: non-dose checked 1000 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 1000 C++ Note: risk checked 1000 C++ Note: risk1 checked 1626.94 C++ Note: risk2 checked 4593.87 C++ Note: Made Risk Side Lists C++ Note: riskr checked 12119 C++ Note: risk1r checked 18778.8 C++ Note: risk2r checked 45501.3 C++ Note: riskl checked 114 C++ Note: risk1l checked 212.971 C++ Note: risk2l checked 576.121 C++ Note: df101 -525.776 C++ Note: df102 -4.07712 C++ Note: df103 -39.3287 C++ Note: df104 0 C++ Note: df105 0.103668 C++ Note: df106 128.958 C++ Note: riskr checked 12119 C++ Note: risk1r checked 18778.8 C++ Note: risk2r checked 45501.3 C++ Note: riskl checked 114 C++ Note: risk1l checked 212.971 C++ Note: risk2l checked 576.121 C++ Note: df101 -525.776 C++ Note: df102 -4.07712 C++ Note: df103 -39.3287 C++ Note: df104 0 C++ Note: df105 0.103668 C++ Note: df106 128.958 C++ Note: ending guess 0 C++ Note: df501 -525.7764 C++ Note: df504 0 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0, -525.7764<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0 C++ Note: sums checked 1000 C++ Note: derivs checked 1626.94 C++ Note: second derivs checked 4593.87 C++ Note: dose checked 1000 C++ Note: non-dose checked 1000 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 1000 C++ Note: risk checked 1000 C++ Note: risk1 checked 1626.94 C++ Note: risk2 checked 4593.87 C++ Note: Made Risk Side Lists C++ Note: riskr checked 12119 C++ Note: risk1r checked 18778.8 C++ Note: risk2r checked 45501.3 C++ Note: riskl checked 114 C++ Note: risk1l checked 212.971 C++ Note: risk2l checked 576.121 C++ Note: df101 -525.776 C++ Note: df102 -4.07712 C++ Note: df103 -39.3287 C++ Note: df104 0 C++ Note: df105 0.103668 C++ Note: df106 128.958 C++ Note: riskr checked 12119 C++ Note: risk1r checked 18778.8 C++ Note: risk2r checked 45501.3 C++ Note: riskl checked 114 C++ Note: risk1l checked 212.971 C++ Note: risk2l checked 576.121 C++ Note: df101 -525.776 C++ Note: df102 -4.07712 C++ Note: df103 -39.3287 C++ Note: df104 0 C++ Note: df105 0.103668 C++ Note: df106 128.958 C++ Note: Exiting Regression C++ Note: df501 -525.7764 C++ Note: df504 0 Note: 114 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 421 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 12119 C++ Note: riskl checked 114 Note: 114 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 C++ Note: df99,22,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 457 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked 0 C++ Note: sums checked 1000 C++ Note: risk checked 1000 C++ Note: risk1 checked 1626.94 C++ Note: risk2 checked 4593.87 C++ Note: Made Risk Side Lists C++ Note: riskr checked 12119 C++ Note: riskl checked 114 C++ Note: df101 -525.776 C++ Note: df104 0 C++ Note: riskr checked 12119 C++ Note: riskl checked 114 C++ Note: df101 -525.776 C++ Note: df104 0 C++ Note: ending guess 0 C++ Note: df501 -525.7764 C++ Note: df504 0 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0, -525.7764<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0 C++ Note: sums checked 1000 C++ Note: risk checked 1000 C++ Note: risk1 checked 1626.94 C++ Note: risk2 checked 4593.87 C++ Note: Made Risk Side Lists C++ Note: riskr checked 12119 C++ Note: riskl checked 114 C++ Note: df101 -525.776 C++ Note: df104 0 C++ Note: riskr checked 12119 C++ Note: riskl checked 114 C++ Note: df101 -525.776 C++ Note: df104 0 C++ Note: Exiting Regression C++ Note: df501 -525.7764 C++ Note: df504 0 Note: 114 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 420 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 12119 C++ Note: riskl checked 114 Note: 114 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 C++ Note: df99,22,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 622 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked 0 C++ Note: sums checked 1000 C++ Note: risk checked 1000 C++ Note: risk1 checked 1626.94 C++ Note: risk2 checked 4593.87 C++ Note: Made Risk Side Lists C++ Note: riskr checked 12119 C++ Note: risk1r checked 18778.8 C++ Note: risk2r checked 45501.3 C++ Note: riskl checked 114 C++ Note: risk1l checked 212.971 C++ Note: risk2l checked 576.121 C++ Note: df101 -525.776 C++ Note: df102 -4.07712 C++ Note: df103 -39.3287 C++ Note: df104 0 C++ Note: df105 0.103668 C++ Note: df106 128.958 C++ Note: riskr checked 12119 C++ Note: risk1r checked 18778.8 C++ Note: risk2r checked 45501.3 C++ Note: riskl checked 114 C++ Note: risk1l checked 212.971 C++ Note: risk2l checked 576.121 C++ Note: df101 -525.776 C++ Note: df102 -4.07712 C++ Note: df103 -39.3287 C++ Note: df104 0 C++ Note: df105 0.103668 C++ Note: df106 128.958 C++ Note: ending guess 0 C++ Note: df501 -525.7764 C++ Note: df504 0 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0, -525.7764<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0 C++ Note: sums checked 1000 C++ Note: risk checked 1000 C++ Note: risk1 checked 1626.94 C++ Note: risk2 checked 4593.87 C++ Note: Made Risk Side Lists C++ Note: riskr checked 12119 C++ Note: risk1r checked 18778.8 C++ Note: risk2r checked 45501.3 C++ Note: riskl checked 114 C++ Note: risk1l checked 212.971 C++ Note: risk2l checked 576.121 C++ Note: df101 -525.776 C++ Note: df102 -4.07712 C++ Note: df103 -39.3287 C++ Note: df104 0 C++ Note: df105 0.103668 C++ Note: df106 128.958 C++ Note: riskr checked 12119 C++ Note: risk1r checked 18778.8 C++ Note: risk2r checked 45501.3 C++ Note: riskl checked 114 C++ Note: risk1l checked 212.971 C++ Note: risk2l checked 576.121 C++ Note: df101 -525.776 C++ Note: df102 -4.07712 C++ Note: df103 -39.3287 C++ Note: df104 0 C++ Note: df105 0.103668 C++ Note: df106 128.958 C++ Note: Exiting Regression C++ Note: df501 -525.7764 C++ Note: df504 0 Note: 114 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 455 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 12119 C++ Note: riskl checked 114 Note: 114 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 C++ Note: df99,31,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 513 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked 0 C++ Note: sums checked 1000 C++ Note: dose checked 1000 C++ Note: non-dose checked 1000 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 1000 C++ Note: risk checked 1000 C++ Note: Made Risk Side Lists C++ Note: riskr checked 12119 C++ Note: riskl checked 114 C++ Note: df101 -525.776 C++ Note: df104 0 C++ Note: riskr checked 12119 C++ Note: riskl checked 114 C++ Note: df101 -525.776 C++ Note: df104 0 C++ Note: ending guess 0 C++ Note: df501 -525.7764 C++ Note: df504 0 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0, -525.7764<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0 C++ Note: sums checked 1000 C++ Note: dose checked 1000 C++ Note: non-dose checked 1000 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 1000 C++ Note: risk checked 1000 C++ Note: Made Risk Side Lists C++ Note: riskr checked 12119 C++ Note: riskl checked 114 C++ Note: df101 -525.776 C++ Note: df104 0 C++ Note: riskr checked 12119 C++ Note: riskl checked 114 C++ Note: df101 -525.776 C++ Note: df104 0 C++ Note: Exiting Regression C++ Note: df501 -525.7764 C++ Note: df504 0 Note: 114 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 417 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 12119 C++ Note: riskl checked 114 Note: 114 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 C++ Note: df99,22,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 460 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked 0 C++ Note: sums checked 1000 C++ Note: derivs checked 1626.94 C++ Note: second derivs checked 4593.87 C++ Note: dose checked 1000 C++ Note: non-dose checked 1000 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 1000 C++ Note: risk checked 1000 C++ Note: risk1 checked 1626.94 C++ Note: risk2 checked 4593.87 C++ Note: Made Risk Side Lists C++ Note: riskr checked 12119 C++ Note: risk1r checked 18778.8 C++ Note: risk2r checked 45501.3 C++ Note: riskl checked 114 C++ Note: risk1l checked 212.971 C++ Note: risk2l checked 576.121 C++ Note: df101 -525.776 C++ Note: df102 -4.07712 C++ Note: df103 -39.3287 C++ Note: df104 0 C++ Note: df105 0.103668 C++ Note: df106 128.958 C++ Note: riskr checked 12119 C++ Note: risk1r checked 18778.8 C++ Note: risk2r checked 45501.3 C++ Note: riskl checked 114 C++ Note: risk1l checked 212.971 C++ Note: risk2l checked 576.121 C++ Note: df101 -525.776 C++ Note: df102 -4.07712 C++ Note: df103 -39.3287 C++ Note: df104 0 C++ Note: df105 0.103668 C++ Note: df106 128.958 C++ Note: ending guess 0 C++ Note: df501 -525.7764 C++ Note: df504 0 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0, -525.7764<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0 C++ Note: sums checked 1000 C++ Note: derivs checked 1626.94 C++ Note: second derivs checked 4593.87 C++ Note: dose checked 1000 C++ Note: non-dose checked 1000 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 1000 C++ Note: risk checked 1000 C++ Note: risk1 checked 1626.94 C++ Note: risk2 checked 4593.87 C++ Note: Made Risk Side Lists C++ Note: riskr checked 12119 C++ Note: risk1r checked 18778.8 C++ Note: risk2r checked 45501.3 C++ Note: riskl checked 114 C++ Note: risk1l checked 212.971 C++ Note: risk2l checked 576.121 C++ Note: df101 -525.776 C++ Note: df102 -4.07712 C++ Note: df103 -39.3287 C++ Note: df104 0 C++ Note: df105 0.103668 C++ Note: df106 128.958 C++ Note: riskr checked 12119 C++ Note: risk1r checked 18778.8 C++ Note: risk2r checked 45501.3 C++ Note: riskl checked 114 C++ Note: risk1l checked 212.971 C++ Note: risk2l checked 576.121 C++ Note: df101 -525.776 C++ Note: df102 -4.07712 C++ Note: df103 -39.3287 C++ Note: df104 0 C++ Note: df105 0.103668 C++ Note: df106 128.958 C++ Note: Exiting Regression C++ Note: df501 -525.7764 C++ Note: df504 0 Note: 901 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 0 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 2985 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked 0 0 C++ Note: sums checked 1000 1000 C++ Note: derivs checked 531 C++ Note: second derivs checked 531 C++ Note: dose checked 1000 C++ Note: non-dose checked 1000 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 1000 C++ Note: risk checked 1000 C++ Note: risk1 checked 531 C++ Note: risk2 checked 531 C++ Note: Made Risk Side Lists C++ Note: riskr checked 94828 C++ Note: risk1r checked 50387 C++ Note: risk2r checked 50387 C++ Note: riskl checked 901 C++ Note: risk1l checked 479 C++ Note: risk2l checked 479 C++ Note: df101 -4115.03 C++ Note: df102 1.62 C++ Note: df103 -222.912 C++ Note: df104 0 0 C++ Note: df105 -0.00726744 C++ Note: df106 -2540.14 C++ Note: Starting Halves C++ Note: df501 -4115.028 C++ Note: df504 0 0 C++ Note: values checked 0 0.00545058 C++ Note: sums checked 1000 1002.9 C++ Note: derivs checked 533.902 C++ Note: second derivs checked 533.902 C++ Note: dose checked 1000 C++ Note: non-dose checked 1002.9 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 1002.9 C++ Note: risk checked 1002.9 C++ Note: risk1 checked 533.902 C++ Note: risk2 checked 533.902 C++ Note: riskr checked 95103.4 C++ Note: risk1r checked 50662.4 C++ Note: risk2r checked 50662.4 C++ Note: riskl checked 903.618 C++ Note: risk1l checked 481.618 C++ Note: risk2l checked 481.618 C++ Note: df101 -4115.02 C++ Note: df102 0.405212 C++ Note: df103 -222.834 C++ Note: df104 0 0.00545058 C++ Note: df105 -0.00181845 C++ Note: df106 -10155.2 C++ Note: df100 9473 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 95103.4 C++ Note: risk1r checked 50662.4 C++ Note: risk2r checked 50662.4 C++ Note: riskl checked 903.618 C++ Note: risk1l checked 481.618 C++ Note: risk2l checked 481.618 C++ Note: df101 -4115.02 C++ Note: df102 0.405212 C++ Note: df103 -222.834 C++ Note: df104 0 0.00545058 C++ Note: df105 -0.00181845 C++ Note: df106 -10155.2 C++ Note: ending guess 0 C++ Note: df501 -4115.022 C++ Note: df504 0 0.005450583 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0 0.005450583, -4115.022<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0 0.00545058 C++ Note: sums checked 1000 1002.9 C++ Note: derivs checked 533.902 C++ Note: second derivs checked 533.902 C++ Note: dose checked 1000 C++ Note: non-dose checked 1002.9 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 1002.9 C++ Note: risk checked 1002.9 C++ Note: risk1 checked 533.902 C++ Note: risk2 checked 533.902 C++ Note: Made Risk Side Lists C++ Note: riskr checked 95103.4 C++ Note: risk1r checked 50662.4 C++ Note: risk2r checked 50662.4 C++ Note: riskl checked 903.618 C++ Note: risk1l checked 481.618 C++ Note: risk2l checked 481.618 C++ Note: df101 -4115.02 C++ Note: df102 0.405212 C++ Note: df103 -222.834 C++ Note: df104 0 0.00545058 C++ Note: df105 -0.00181845 C++ Note: df106 -10155.2 C++ Note: riskr checked 95103.4 C++ Note: risk1r checked 50662.4 C++ Note: risk2r checked 50662.4 C++ Note: riskl checked 903.618 C++ Note: risk1l checked 481.618 C++ Note: risk2l checked 481.618 C++ Note: df101 -4115.02 C++ Note: df102 0.405212 C++ Note: df103 -222.834 C++ Note: df104 0 0.00545058 C++ Note: df105 -0.00181845 C++ Note: df106 -10155.2 C++ Note: Exiting Regression C++ Note: df501 -4115.022 C++ Note: df504 0 0.005450583 C++ Note: START_PLOT C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 0 C++ Note: df99,27,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: values checked 0 0 C++ Note: sums checked 1000 1000 C++ Note: derivs checked 531 C++ Note: second derivs checked 531 C++ Note: dose checked 1000 C++ Note: non-dose checked 1000 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 1000 C++ Note: risk checked 1000 C++ Note: risk1 checked 531 C++ Note: risk2 checked 531 C++ Note: Grouping Start C++ Note: df100 3339 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Made Risk Side Lists C++ Note: riskr checked 94828 C++ Note: risk1r checked 50387 C++ Note: risk2r checked 50387 C++ Note: riskl checked 901 C++ Note: risk1l checked 479 C++ Note: risk2l checked 479 C++ Note: df101 -4115.03 C++ Note: df102 1.62 C++ Note: df103 -222.912 C++ Note: df104 0 0 C++ Note: df105 -0.00726744 C++ Note: df106 -2540.14 Saving 7 x 7 in image Note: 5 strata used Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 0 C++ Note: df99,29,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 475 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -82.55461 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: df100 1673 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: df100 2194 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: ending guess 0 C++ Note: df501 -82.55461 C++ Note: df504 -0.1 -0.1 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1 -0.1, -82.55461<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -82.55461 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: df100 3777 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: df100 4328 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: Exiting Regression C++ Note: df501 -82.55461 C++ Note: df504 -0.1 -0.1 Note: 5 strata used Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 0 C++ Note: df99,25,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 342 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -82.55461 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: df100 1384 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: df100 1905 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: ending guess 0 C++ Note: df501 -82.55461 C++ Note: df504 -0.1 -0.1 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1 -0.1, -82.55461<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -82.55461 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: df100 3373 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: df100 3898 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: Exiting Regression C++ Note: df501 -82.55461 C++ Note: df504 -0.1 -0.1 Note: 5 strata used Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 0 C++ Note: df99,25,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 324 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -79.58847 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: df100 1296 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: df100 1770 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: ending guess 0 C++ Note: df501 -79.58847 C++ Note: df504 -0.1 -0.1 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1 -0.1, -79.58847<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -79.58847 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: df100 3069 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: Exiting Regression C++ Note: df501 -79.58847 C++ Note: df504 -0.1 -0.1 Note: 5 strata used Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 0 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 318 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -79.58847 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: df100 1267 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: df100 1737 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: ending guess 0 C++ Note: df501 -79.58847 C++ Note: df504 -0.1 -0.1 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1 -0.1, -79.58847<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -79.58847 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: df100 2998 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: df100 3463 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: Exiting Regression C++ Note: df501 -79.58847 C++ Note: df504 -0.1 -0.1 Note: 5 strata used Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 0 C++ Note: df99,25,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 334 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df102 19.8692 3.2049 C++ Note: df103 -19.1334 -6.17679 C++ Note: df104 -0.1 -0.1 C++ Note: df105 -1.03846 -0.518862 C++ Note: df106 -4.1549 -25.7589 C++ Note: Starting Halves C++ Note: df501 -82.55461 C++ Note: df504 -0.1 -0.1 C++ Note: values checked 0.702609 0.405935 C++ Note: sums checked 5765.37 1265.87 C++ Note: risk checked 7235.91 C++ Note: risk1 checked 23875.5 4407.46 C++ Note: risk2 checked 95114.7 4407.46 C++ Note: riskr checked 1029.36 657.301 440.368 779.123 340.451 C++ Note: riskl checked 83.3734 40.9432 39.5706 39.8431 33.7665 C++ Note: df101 -71.2819 -71.2819 C++ Note: df102 6.53346 0.663705 C++ Note: df103 -13.6957 -6.04035 C++ Note: df104 0.702609 0.405935 C++ Note: df105 -0.477045 -0.109879 C++ Note: df106 -10.9103 -107.4 C++ Note: df100 2225 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 1029.36 657.301 440.368 779.123 340.451 C++ Note: riskl checked 83.3734 40.9432 39.5706 39.8431 33.7665 C++ Note: df101 -71.2819 -71.2819 C++ Note: df102 6.53346 0.663705 C++ Note: df103 -13.6957 -6.04035 C++ Note: df104 0.702609 0.405935 C++ Note: df105 -0.477045 -0.109879 C++ Note: df106 -10.9103 -107.4 C++ Note: ending guess 0 C++ Note: df501 -71.28193 C++ Note: df504 0.7026092 0.4059355 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.7026092 0.4059355, -71.28193<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0.702609 0.405935 C++ Note: sums checked 5765.37 1265.87 C++ Note: risk checked 7235.91 C++ Note: risk1 checked 23875.5 4407.46 C++ Note: risk2 checked 95114.7 4407.46 C++ Note: Made Risk Side Lists C++ Note: riskr checked 1029.36 657.301 440.368 779.123 340.451 C++ Note: riskl checked 83.3734 40.9432 39.5706 39.8431 33.7665 C++ Note: df101 -71.2819 -71.2819 C++ Note: df102 6.53346 0.663705 C++ Note: df103 -13.6957 -6.04035 C++ Note: df104 0.702609 0.405935 C++ Note: df105 -0.477045 -0.109879 C++ Note: df106 -10.9103 -107.4 C++ Note: Starting Halves C++ Note: df501 -71.28193 C++ Note: df504 0.7026092 0.4059355 C++ Note: values checked 1.06614 0.527334 C++ Note: sums checked 22078.7 1368.73 C++ Note: risk checked 29733.3 C++ Note: risk1 checked 119904 18677.8 C++ Note: risk2 checked 536010 18677.8 C++ Note: riskr checked 4013.84 1761.95 1075.19 2341.29 1010.29 C++ Note: riskl checked 390.452 140.821 119.569 110.838 125.172 C++ Note: df101 -69.6786 -69.6786 C++ Note: df102 2.18197 0.178373 C++ Note: df103 -10.8366 -5.93902 C++ Note: df104 1.06614 0.527334 C++ Note: df105 -0.201352 -0.0300341 C++ Note: df106 -31.9338 -390.634 C++ Note: df100 4882 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 4013.84 1761.95 1075.19 2341.29 1010.29 C++ Note: riskl checked 390.452 140.821 119.569 110.838 125.172 C++ Note: df101 -69.6786 -69.6786 C++ Note: df102 2.18197 0.178373 C++ Note: df103 -10.8366 -5.93902 C++ Note: df104 1.06614 0.527334 C++ Note: df105 -0.201352 -0.0300341 C++ Note: df106 -31.9338 -390.634 C++ Note: riskr checked 4013.84 1761.95 1075.19 2341.29 1010.29 C++ Note: riskl checked 390.452 140.821 119.569 110.838 125.172 C++ Note: df101 -69.6786 -69.6786 C++ Note: df102 2.18197 0.178373 C++ Note: df103 -10.8366 -5.93902 C++ Note: df104 1.06614 0.527334 C++ Note: df105 -0.201352 -0.0300341 C++ Note: df106 -31.9338 -390.634 C++ Note: Exiting Regression C++ Note: df501 -69.67859 C++ Note: df504 1.066135 0.5273336 Note: 5 strata used Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 0 C++ Note: df99,25,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 339 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df102 19.8692 3.2049 C++ Note: df103 -19.1334 -6.17679 C++ Note: df104 -0.1 -0.1 C++ Note: df105 -1.03846 -0.518862 C++ Note: df106 -4.1549 -25.7589 C++ Note: Starting Halves C++ Note: df501 -82.55461 C++ Note: df504 -0.1 -0.1 C++ Note: values checked 0.678843 0.289146 C++ Note: sums checked 5332.15 1178.04 C++ Note: risk checked 6244.38 C++ Note: risk1 checked 20292.1 3632.95 C++ Note: risk2 checked 80174.7 3632.95 C++ Note: riskr checked 899.189 581.433 385.076 688.511 299.436 C++ Note: riskl checked 70.4668 36.2982 33.2589 35.4616 28.5259 C++ Note: df101 -71.5582 -71.5582 C++ Note: df102 6.7855 1.35947 C++ Note: df103 -13.923 -6.13436 C++ Note: df104 0.678843 0.289146 C++ Note: df105 -0.487357 -0.221615 C++ Note: df106 -10.5458 -52.6369 C++ Note: df100 2222 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 899.189 581.433 385.076 688.511 299.436 C++ Note: riskl checked 70.4668 36.2982 33.2589 35.4616 28.5259 C++ Note: df101 -71.5582 -71.5582 C++ Note: df102 6.7855 1.35947 C++ Note: df103 -13.923 -6.13436 C++ Note: df104 0.678843 0.289146 C++ Note: df105 -0.487357 -0.221615 C++ Note: df106 -10.5458 -52.6369 C++ Note: ending guess 0 C++ Note: df501 -71.55823 C++ Note: df504 0.6788427 0.2891462 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.6788427 0.2891462, -71.55823<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0.678843 0.289146 C++ Note: sums checked 5332.15 1178.04 C++ Note: risk checked 6244.38 C++ Note: risk1 checked 20292.1 3632.95 C++ Note: risk2 checked 80174.7 3632.95 C++ Note: Made Risk Side Lists C++ Note: riskr checked 899.189 581.433 385.076 688.511 299.436 C++ Note: riskl checked 70.4668 36.2982 33.2589 35.4616 28.5259 C++ Note: df101 -71.5582 -71.5582 C++ Note: df102 6.7855 1.35947 C++ Note: df103 -13.923 -6.13436 C++ Note: df104 0.678843 0.289146 C++ Note: df105 -0.487357 -0.221615 C++ Note: df106 -10.5458 -52.6369 C++ Note: Starting Halves C++ Note: df501 -71.55823 C++ Note: df504 0.6788427 0.2891462 C++ Note: values checked 1.04436 0.455358 C++ Note: sums checked 20227 1306.25 C++ Note: risk checked 26056 C++ Note: risk1 checked 104097 15935.8 C++ Note: risk2 checked 462614 15935.8 C++ Note: riskr checked 3566.45 1594.5 968.276 2102.11 897.328 C++ Note: riskl checked 341.759 127.646 104.884 101.194 108.836 C++ Note: df101 -69.7559 -69.7559 C++ Note: df102 2.37027 0.59374 C++ Note: df103 -10.9895 -6.01548 C++ Note: df104 1.04436 0.455358 C++ Note: df105 -0.215686 -0.0987019 C++ Note: df106 -29.4295 -117.486 C++ Note: df100 4864 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 3566.45 1594.5 968.276 2102.11 897.328 C++ Note: riskl checked 341.759 127.646 104.884 101.194 108.836 C++ Note: df101 -69.7559 -69.7559 C++ Note: df102 2.37027 0.59374 C++ Note: df103 -10.9895 -6.01548 C++ Note: df104 1.04436 0.455358 C++ Note: df105 -0.215686 -0.0987019 C++ Note: df106 -29.4295 -117.486 C++ Note: riskr checked 3566.45 1594.5 968.276 2102.11 897.328 C++ Note: riskl checked 341.759 127.646 104.884 101.194 108.836 C++ Note: df101 -69.7559 -69.7559 C++ Note: df102 2.37027 0.59374 C++ Note: df103 -10.9895 -6.01548 C++ Note: df104 1.04436 0.455358 C++ Note: df105 -0.215686 -0.0987019 C++ Note: df106 -29.4295 -117.486 C++ Note: Exiting Regression C++ Note: df501 -69.7559 C++ Note: df504 1.044361 0.4553577 Note: 5 strata used Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 0 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 321 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df102 5.42704 2.14202 C++ Note: df103 -7.11684 -6.21271 C++ Note: df104 -0.1 -0.1 C++ Note: df105 -0.762564 -0.34478 C++ Note: df106 -14.6652 -37.1559 C++ Note: Starting Halves C++ Note: df501 -79.58847 C++ Note: df504 -0.1 -0.1 C++ Note: values checked 0.550424 0.30353 C++ Note: sums checked 3575.85 1188.31 C++ Note: risk checked 4228.8 C++ Note: risk1 checked 12473.9 2494.15 C++ Note: risk2 checked 46827.4 2494.15 C++ Note: riskr checked 616.483 485.721 374.917 603.993 261.606 C++ Note: riskl checked 43.76 24.6658 24.1668 25.7075 19.5703 C++ Note: df101 -76.8654 -76.8654 C++ Note: df102 1.27777 0.508497 C++ Note: df103 -7.18963 -6.04474 C++ Note: df104 0.550424 0.30353 C++ Note: df105 -0.177724 -0.0841223 C++ Note: df106 -60.1559 -151.162 C++ Note: df100 1989 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 616.483 485.721 374.917 603.993 261.606 C++ Note: riskl checked 43.76 24.6658 24.1668 25.7075 19.5703 C++ Note: df101 -76.8654 -76.8654 C++ Note: df102 1.27777 0.508497 C++ Note: df103 -7.18963 -6.04474 C++ Note: df104 0.550424 0.30353 C++ Note: df105 -0.177724 -0.0841223 C++ Note: df106 -60.1559 -151.162 C++ Note: ending guess 0 C++ Note: df501 -76.86543 C++ Note: df504 0.5504238 0.3035295 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.5504238 0.3035295, -76.86543<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0.550424 0.30353 C++ Note: sums checked 3575.85 1188.31 C++ Note: risk checked 4228.8 C++ Note: risk1 checked 12473.9 2494.15 C++ Note: risk2 checked 46827.4 2494.15 C++ Note: Made Risk Side Lists C++ Note: riskr checked 616.483 485.721 374.917 603.993 261.606 C++ Note: riskl checked 43.76 24.6658 24.1668 25.7075 19.5703 C++ Note: df101 -76.8654 -76.8654 C++ Note: df102 1.27777 0.508497 C++ Note: df103 -7.18963 -6.04474 C++ Note: df104 0.550424 0.30353 C++ Note: df105 -0.177724 -0.0841223 C++ Note: df106 -60.1559 -151.162 C++ Note: Starting Halves C++ Note: df501 -76.86543 C++ Note: df504 0.5504238 0.3035295 C++ Note: values checked 0.699516 0.396693 C++ Note: sums checked 5706.63 1258.54 C++ Note: risk checked 7122.36 C++ Note: risk1 checked 23453.2 4323.35 C++ Note: risk2 checked 93329.8 4323.35 C++ Note: riskr checked 1103.97 748.255 549.423 973.678 397.318 C++ Note: riskl checked 81.8797 40.3981 38.9034 39.35 33.1873 C++ Note: df101 -76.7167 -76.7167 C++ Note: df102 0.321463 0.127669 C++ Note: df103 -7.13078 -5.96512 C++ Note: df104 0.699516 0.396693 C++ Note: df105 -0.045081 -0.0214027 C++ Note: df106 -238.649 -600.901 C++ Note: df100 4213 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 1103.97 748.255 549.423 973.678 397.318 C++ Note: riskl checked 81.8797 40.3981 38.9034 39.35 33.1873 C++ Note: df101 -76.7167 -76.7167 C++ Note: df102 0.321463 0.127669 C++ Note: df103 -7.13078 -5.96512 C++ Note: df104 0.699516 0.396693 C++ Note: df105 -0.045081 -0.0214027 C++ Note: df106 -238.649 -600.901 C++ Note: riskr checked 1103.97 748.255 549.423 973.678 397.318 C++ Note: riskl checked 81.8797 40.3981 38.9034 39.35 33.1873 C++ Note: df101 -76.7167 -76.7167 C++ Note: df102 0.321463 0.127669 C++ Note: df103 -7.13078 -5.96512 C++ Note: df104 0.699516 0.396693 C++ Note: df105 -0.045081 -0.0214027 C++ Note: df106 -238.649 -600.901 C++ Note: Exiting Regression C++ Note: df501 -76.71665 C++ Note: df504 0.6995155 0.3966929 Note: 5 strata used Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 0 C++ Note: df99,25,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 333 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df102 5.42704 2.14202 C++ Note: df103 -7.11684 -6.21271 C++ Note: df104 -0.1 -0.1 C++ Note: df105 -0.762564 -0.34478 C++ Note: df106 -14.6652 -37.1559 C++ Note: Starting Halves C++ Note: df501 -79.58847 C++ Note: df504 -0.1 -0.1 C++ Note: values checked 0.471923 0.158585 C++ Note: sums checked 2855.18 1091.25 C++ Note: risk checked 3109.21 C++ Note: risk1 checked 8604.8 1732.23 C++ Note: risk2 checked 31265.5 1732.23 C++ Note: riskr checked 437.598 369.44 288.407 451.269 203.987 C++ Note: riskl checked 29.7555 18.4415 17.3204 19.7081 14.0257 C++ Note: df101 -77.1115 -77.1115 C++ Note: df102 1.6628 1.2965 C++ Note: df103 -7.18852 -6.1617 C++ Note: df104 0.471923 0.158585 C++ Note: df105 -0.231313 -0.210412 C++ Note: df106 -46.3745 -59.4767 C++ Note: df100 1928 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 437.598 369.44 288.407 451.269 203.987 C++ Note: riskl checked 29.7555 18.4415 17.3204 19.7081 14.0257 C++ Note: df101 -77.1115 -77.1115 C++ Note: df102 1.6628 1.2965 C++ Note: df103 -7.18852 -6.1617 C++ Note: df104 0.471923 0.158585 C++ Note: df105 -0.231313 -0.210412 C++ Note: df106 -46.3745 -59.4767 C++ Note: ending guess 0 C++ Note: df501 -77.11153 C++ Note: df504 0.4719227 0.1585847 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.4719227 0.1585847, -77.11153<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0.471923 0.158585 C++ Note: sums checked 2855.18 1091.25 C++ Note: risk checked 3109.21 C++ Note: risk1 checked 8604.8 1732.23 C++ Note: risk2 checked 31265.5 1732.23 C++ Note: Made Risk Side Lists C++ Note: riskr checked 437.598 369.44 288.407 451.269 203.987 C++ Note: riskl checked 29.7555 18.4415 17.3204 19.7081 14.0257 C++ Note: df101 -77.1115 -77.1115 C++ Note: df102 1.6628 1.2965 C++ Note: df103 -7.18852 -6.1617 C++ Note: df104 0.471923 0.158585 C++ Note: df105 -0.231313 -0.210412 C++ Note: df106 -46.3745 -59.4767 C++ Note: Starting Halves C++ Note: df501 -77.11153 C++ Note: df504 0.4719227 0.1585847 C++ Note: values checked 0.645408 0.316394 C++ Note: sums checked 4787.64 1197.62 C++ Note: risk checked 5698.95 C++ Note: risk1 checked 18076.9 3359.94 C++ Note: risk2 checked 70503.7 3359.94 C++ Note: riskr checked 866.381 621.431 461.192 794.093 330.167 C++ Note: riskl checked 63.0668 33.0727 31.2711 32.9428 26.3017 C++ Note: df101 -76.7689 -76.7689 C++ Note: df102 0.612277 0.54564 C++ Note: df103 -7.1484 -6.0464 C++ Note: df104 0.645408 0.316394 C++ Note: df105 -0.0856523 -0.0902421 C++ Note: df106 -125.383 -140.695 C++ Note: df100 4141 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 866.381 621.431 461.192 794.093 330.167 C++ Note: riskl checked 63.0668 33.0727 31.2711 32.9428 26.3017 C++ Note: df101 -76.7689 -76.7689 C++ Note: df102 0.612277 0.54564 C++ Note: df103 -7.1484 -6.0464 C++ Note: df104 0.645408 0.316394 C++ Note: df105 -0.0856523 -0.0902421 C++ Note: df106 -125.383 -140.695 C++ Note: riskr checked 866.381 621.431 461.192 794.093 330.167 C++ Note: riskl checked 63.0668 33.0727 31.2711 32.9428 26.3017 C++ Note: df101 -76.7689 -76.7689 C++ Note: df102 0.612277 0.54564 C++ Note: df103 -7.1484 -6.0464 C++ Note: df104 0.645408 0.316394 C++ Note: df105 -0.0856523 -0.0902421 C++ Note: df106 -125.383 -140.695 C++ Note: Exiting Regression C++ Note: df501 -76.76892 C++ Note: df504 0.6454076 0.316394 Note: 5 strata used Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 0 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 332 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: Made Risk Side Lists C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -82.55461 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: df100 1467 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: df100 2001 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: ending guess 0 C++ Note: df501 -82.55461 C++ Note: df504 -0.1 -0.1 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1 -0.1, -82.55461<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: Made Risk Side Lists C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -82.55461 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: df100 3470 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: df100 3999 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: Exiting Regression C++ Note: df501 -82.55461 C++ Note: df504 -0.1 -0.1 Note: 5 strata used Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 0 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 323 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: Made Risk Side Lists C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -82.55461 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: df100 1421 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: ending guess 0 C++ Note: df501 -82.55461 C++ Note: df504 -0.1 -0.1 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1 -0.1, -82.55461<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: Made Risk Side Lists C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -82.55461 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: df100 2854 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df104 -0.1 -0.1 C++ Note: Exiting Regression C++ Note: df501 -82.55461 C++ Note: df504 -0.1 -0.1 Note: 5 strata used Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 0 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 327 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: Made Risk Side Lists C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -79.58847 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: df100 1346 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: df100 1832 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: ending guess 0 C++ Note: df501 -79.58847 C++ Note: df504 -0.1 -0.1 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1 -0.1, -79.58847<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: Made Risk Side Lists C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -79.58847 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: df100 3151 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: df100 3637 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: Exiting Regression C++ Note: df501 -79.58847 C++ Note: df504 -0.1 -0.1 Note: 5 strata used Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 0 C++ Note: df99,25,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 304 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: Made Risk Side Lists C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -79.58847 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: df100 1302 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: df100 1790 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: ending guess 0 C++ Note: df501 -79.58847 C++ Note: df504 -0.1 -0.1 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1 -0.1, -79.58847<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: Made Risk Side Lists C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -79.58847 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: df100 3098 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: df100 3584 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df104 -0.1 -0.1 C++ Note: Exiting Regression C++ Note: df501 -79.58847 C++ Note: df504 -0.1 -0.1 Note: 5 strata used Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 0 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 335 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: derivs checked 1229.85 410.233 C++ Note: second derivs checked 3319.14 410.233 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df102 19.8692 3.2049 C++ Note: df103 -19.1334 -6.17679 C++ Note: df104 -0.1 -0.1 C++ Note: df105 -1.03846 -0.518862 C++ Note: df106 -4.1549 -25.7589 C++ Note: Starting Halves C++ Note: df501 -82.55461 C++ Note: df504 -0.1 -0.1 C++ Note: values checked 0.702609 0.405935 C++ Note: sums checked 7235.91 7235.91 C++ Note: derivs checked 23875.5 4407.46 C++ Note: second derivs checked 95114.7 4407.46 C++ Note: dose checked 1000 C++ Note: non-dose checked 7235.91 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 7235.91 C++ Note: risk checked 7235.91 C++ Note: risk1 checked 23875.5 4407.46 C++ Note: risk2 checked 95114.7 4407.46 C++ Note: riskr checked 1029.36 657.301 440.368 779.123 340.451 C++ Note: riskl checked 83.3734 40.9432 39.5706 39.8431 33.7665 C++ Note: df101 -71.2819 -71.2819 C++ Note: df102 6.53346 0.663705 C++ Note: df103 -13.6957 -6.04035 C++ Note: df104 0.702609 0.405935 C++ Note: df105 -0.477045 -0.109879 C++ Note: df106 -10.9103 -107.4 C++ Note: df100 2786 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 1029.36 657.301 440.368 779.123 340.451 C++ Note: riskl checked 83.3734 40.9432 39.5706 39.8431 33.7665 C++ Note: df101 -71.2819 -71.2819 C++ Note: df102 6.53346 0.663705 C++ Note: df103 -13.6957 -6.04035 C++ Note: df104 0.702609 0.405935 C++ Note: df105 -0.477045 -0.109879 C++ Note: df106 -10.9103 -107.4 C++ Note: ending guess 0 C++ Note: df501 -71.28193 C++ Note: df504 0.7026092 0.4059355 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.7026092 0.4059355, -71.28193<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0.702609 0.405935 C++ Note: sums checked 7235.91 7235.91 C++ Note: derivs checked 23875.5 4407.46 C++ Note: second derivs checked 95114.7 4407.46 C++ Note: dose checked 1000 C++ Note: non-dose checked 7235.91 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 7235.91 C++ Note: risk checked 7235.91 C++ Note: risk1 checked 23875.5 4407.46 C++ Note: risk2 checked 95114.7 4407.46 C++ Note: Made Risk Side Lists C++ Note: riskr checked 1029.36 657.301 440.368 779.123 340.451 C++ Note: riskl checked 83.3734 40.9432 39.5706 39.8431 33.7665 C++ Note: df101 -71.2819 -71.2819 C++ Note: df102 6.53346 0.663705 C++ Note: df103 -13.6957 -6.04035 C++ Note: df104 0.702609 0.405935 C++ Note: df105 -0.477045 -0.109879 C++ Note: df106 -10.9103 -107.4 C++ Note: Starting Halves C++ Note: df501 -71.28193 C++ Note: df504 0.7026092 0.4059355 C++ Note: values checked 1.06614 0.527334 C++ Note: sums checked 29733.3 29733.3 C++ Note: derivs checked 119904 18677.8 C++ Note: second derivs checked 536010 18677.8 C++ Note: dose checked 1000 C++ Note: non-dose checked 29733.3 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 29733.3 C++ Note: risk checked 29733.3 C++ Note: risk1 checked 119904 18677.8 C++ Note: risk2 checked 536010 18677.8 C++ Note: riskr checked 4013.84 1761.95 1075.19 2341.29 1010.29 C++ Note: riskl checked 390.452 140.821 119.569 110.838 125.172 C++ Note: df101 -69.6786 -69.6786 C++ Note: df102 2.18197 0.178373 C++ Note: df103 -10.8366 -5.93902 C++ Note: df104 1.06614 0.527334 C++ Note: df105 -0.201352 -0.0300341 C++ Note: df106 -31.9338 -390.634 C++ Note: df100 5953 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 4013.84 1761.95 1075.19 2341.29 1010.29 C++ Note: riskl checked 390.452 140.821 119.569 110.838 125.172 C++ Note: df101 -69.6786 -69.6786 C++ Note: df102 2.18197 0.178373 C++ Note: df103 -10.8366 -5.93902 C++ Note: df104 1.06614 0.527334 C++ Note: df105 -0.201352 -0.0300341 C++ Note: df106 -31.9338 -390.634 C++ Note: riskr checked 4013.84 1761.95 1075.19 2341.29 1010.29 C++ Note: riskl checked 390.452 140.821 119.569 110.838 125.172 C++ Note: df101 -69.6786 -69.6786 C++ Note: df102 2.18197 0.178373 C++ Note: df103 -10.8366 -5.93902 C++ Note: df104 1.06614 0.527334 C++ Note: df105 -0.201352 -0.0300341 C++ Note: df106 -31.9338 -390.634 C++ Note: Exiting Regression C++ Note: df501 -69.67859 C++ Note: df504 1.066135 0.5273336 Note: 5 strata used Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 0 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 398 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: derivs checked 1229.85 410.233 C++ Note: second derivs checked 3319.14 410.233 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 109.969 102.565 75.071 118.205 66.864 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -82.5546 -82.5546 C++ Note: df102 19.8692 3.2049 C++ Note: df103 -19.1334 -6.17679 C++ Note: df104 -0.1 -0.1 C++ Note: df105 -1.03846 -0.518862 C++ Note: df106 -4.1549 -25.7589 C++ Note: Starting Halves C++ Note: df501 -82.55461 C++ Note: df504 -0.1 -0.1 C++ Note: values checked 0.678843 0.289146 C++ Note: sums checked 6244.38 6244.38 C++ Note: derivs checked 20292.1 3632.95 C++ Note: second derivs checked 80174.7 3632.95 C++ Note: dose checked 1000 C++ Note: non-dose checked 6244.38 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 6244.38 C++ Note: risk checked 6244.38 C++ Note: risk1 checked 20292.1 3632.95 C++ Note: risk2 checked 80174.7 3632.95 C++ Note: riskr checked 899.189 581.433 385.076 688.511 299.436 C++ Note: riskl checked 70.4668 36.2982 33.2589 35.4616 28.5259 C++ Note: df101 -71.5582 -71.5582 C++ Note: df102 6.7855 1.35947 C++ Note: df103 -13.923 -6.13436 C++ Note: df104 0.678843 0.289146 C++ Note: df105 -0.487357 -0.221615 C++ Note: df106 -10.5458 -52.6369 C++ Note: df100 2804 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 899.189 581.433 385.076 688.511 299.436 C++ Note: riskl checked 70.4668 36.2982 33.2589 35.4616 28.5259 C++ Note: df101 -71.5582 -71.5582 C++ Note: df102 6.7855 1.35947 C++ Note: df103 -13.923 -6.13436 C++ Note: df104 0.678843 0.289146 C++ Note: df105 -0.487357 -0.221615 C++ Note: df106 -10.5458 -52.6369 C++ Note: ending guess 0 C++ Note: df501 -71.55823 C++ Note: df504 0.6788427 0.2891462 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.6788427 0.2891462, -71.55823<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0.678843 0.289146 C++ Note: sums checked 6244.38 6244.38 C++ Note: derivs checked 20292.1 3632.95 C++ Note: second derivs checked 80174.7 3632.95 C++ Note: dose checked 1000 C++ Note: non-dose checked 6244.38 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 6244.38 C++ Note: risk checked 6244.38 C++ Note: risk1 checked 20292.1 3632.95 C++ Note: risk2 checked 80174.7 3632.95 C++ Note: Made Risk Side Lists C++ Note: riskr checked 899.189 581.433 385.076 688.511 299.436 C++ Note: riskl checked 70.4668 36.2982 33.2589 35.4616 28.5259 C++ Note: df101 -71.5582 -71.5582 C++ Note: df102 6.7855 1.35947 C++ Note: df103 -13.923 -6.13436 C++ Note: df104 0.678843 0.289146 C++ Note: df105 -0.487357 -0.221615 C++ Note: df106 -10.5458 -52.6369 C++ Note: Starting Halves C++ Note: df501 -71.55823 C++ Note: df504 0.6788427 0.2891462 C++ Note: values checked 1.04436 0.455358 C++ Note: sums checked 26056 26056 C++ Note: derivs checked 104097 15935.8 C++ Note: second derivs checked 462614 15935.8 C++ Note: dose checked 1000 C++ Note: non-dose checked 26056 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 26056 C++ Note: risk checked 26056 C++ Note: risk1 checked 104097 15935.8 C++ Note: risk2 checked 462614 15935.8 C++ Note: riskr checked 3566.45 1594.5 968.276 2102.11 897.328 C++ Note: riskl checked 341.759 127.646 104.884 101.194 108.836 C++ Note: df101 -69.7559 -69.7559 C++ Note: df102 2.37027 0.59374 C++ Note: df103 -10.9895 -6.01548 C++ Note: df104 1.04436 0.455358 C++ Note: df105 -0.215686 -0.0987019 C++ Note: df106 -29.4295 -117.486 C++ Note: df100 5977 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 3566.45 1594.5 968.276 2102.11 897.328 C++ Note: riskl checked 341.759 127.646 104.884 101.194 108.836 C++ Note: df101 -69.7559 -69.7559 C++ Note: df102 2.37027 0.59374 C++ Note: df103 -10.9895 -6.01548 C++ Note: df104 1.04436 0.455358 C++ Note: df105 -0.215686 -0.0987019 C++ Note: df106 -29.4295 -117.486 C++ Note: riskr checked 3566.45 1594.5 968.276 2102.11 897.328 C++ Note: riskl checked 341.759 127.646 104.884 101.194 108.836 C++ Note: df101 -69.7559 -69.7559 C++ Note: df102 2.37027 0.59374 C++ Note: df103 -10.9895 -6.01548 C++ Note: df104 1.04436 0.455358 C++ Note: df105 -0.215686 -0.0987019 C++ Note: df106 -29.4295 -117.486 C++ Note: Exiting Regression C++ Note: df501 -69.7559 C++ Note: df504 1.044361 0.4553577 Note: 5 strata used Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 0 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 321 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: derivs checked 1229.85 410.233 C++ Note: second derivs checked 3319.14 410.233 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df102 5.42704 2.14202 C++ Note: df103 -7.11684 -6.21271 C++ Note: df104 -0.1 -0.1 C++ Note: df105 -0.762564 -0.34478 C++ Note: df106 -14.6652 -37.1559 C++ Note: Starting Halves C++ Note: df501 -79.58847 C++ Note: df504 -0.1 -0.1 C++ Note: values checked 0.550424 0.30353 C++ Note: sums checked 4228.8 4228.8 C++ Note: derivs checked 12473.9 2494.15 C++ Note: second derivs checked 46827.4 2494.15 C++ Note: dose checked 1000 C++ Note: non-dose checked 4228.8 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 4228.8 C++ Note: risk checked 4228.8 C++ Note: risk1 checked 12473.9 2494.15 C++ Note: risk2 checked 46827.4 2494.15 C++ Note: riskr checked 616.483 485.721 374.917 603.993 261.606 C++ Note: riskl checked 43.76 24.6658 24.1668 25.7075 19.5703 C++ Note: df101 -76.8654 -76.8654 C++ Note: df102 1.27777 0.508497 C++ Note: df103 -7.18963 -6.04474 C++ Note: df104 0.550424 0.30353 C++ Note: df105 -0.177724 -0.0841223 C++ Note: df106 -60.1559 -151.162 C++ Note: df100 2465 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 616.483 485.721 374.917 603.993 261.606 C++ Note: riskl checked 43.76 24.6658 24.1668 25.7075 19.5703 C++ Note: df101 -76.8654 -76.8654 C++ Note: df102 1.27777 0.508497 C++ Note: df103 -7.18963 -6.04474 C++ Note: df104 0.550424 0.30353 C++ Note: df105 -0.177724 -0.0841223 C++ Note: df106 -60.1559 -151.162 C++ Note: ending guess 0 C++ Note: df501 -76.86543 C++ Note: df504 0.5504238 0.3035295 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.5504238 0.3035295, -76.86543<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0.550424 0.30353 C++ Note: sums checked 4228.8 4228.8 C++ Note: derivs checked 12473.9 2494.15 C++ Note: second derivs checked 46827.4 2494.15 C++ Note: dose checked 1000 C++ Note: non-dose checked 4228.8 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 4228.8 C++ Note: risk checked 4228.8 C++ Note: risk1 checked 12473.9 2494.15 C++ Note: risk2 checked 46827.4 2494.15 C++ Note: Made Risk Side Lists C++ Note: riskr checked 616.483 485.721 374.917 603.993 261.606 C++ Note: riskl checked 43.76 24.6658 24.1668 25.7075 19.5703 C++ Note: df101 -76.8654 -76.8654 C++ Note: df102 1.27777 0.508497 C++ Note: df103 -7.18963 -6.04474 C++ Note: df104 0.550424 0.30353 C++ Note: df105 -0.177724 -0.0841223 C++ Note: df106 -60.1559 -151.162 C++ Note: Starting Halves C++ Note: df501 -76.86543 C++ Note: df504 0.5504238 0.3035295 C++ Note: values checked 0.699516 0.396693 C++ Note: sums checked 7122.36 7122.36 C++ Note: derivs checked 23453.2 4323.35 C++ Note: second derivs checked 93329.8 4323.35 C++ Note: dose checked 1000 C++ Note: non-dose checked 7122.36 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 7122.36 C++ Note: risk checked 7122.36 C++ Note: risk1 checked 23453.2 4323.35 C++ Note: risk2 checked 93329.8 4323.35 C++ Note: riskr checked 1103.97 748.255 549.423 973.678 397.318 C++ Note: riskl checked 81.8797 40.3981 38.9034 39.35 33.1873 C++ Note: df101 -76.7167 -76.7167 C++ Note: df102 0.321463 0.127669 C++ Note: df103 -7.13078 -5.96512 C++ Note: df104 0.699516 0.396693 C++ Note: df105 -0.045081 -0.0214027 C++ Note: df106 -238.649 -600.901 C++ Note: df100 5326 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 1103.97 748.255 549.423 973.678 397.318 C++ Note: riskl checked 81.8797 40.3981 38.9034 39.35 33.1873 C++ Note: df101 -76.7167 -76.7167 C++ Note: df102 0.321463 0.127669 C++ Note: df103 -7.13078 -5.96512 C++ Note: df104 0.699516 0.396693 C++ Note: df105 -0.045081 -0.0214027 C++ Note: df106 -238.649 -600.901 C++ Note: riskr checked 1103.97 748.255 549.423 973.678 397.318 C++ Note: riskl checked 81.8797 40.3981 38.9034 39.35 33.1873 C++ Note: df101 -76.7167 -76.7167 C++ Note: df102 0.321463 0.127669 C++ Note: df103 -7.13078 -5.96512 C++ Note: df104 0.699516 0.396693 C++ Note: df105 -0.045081 -0.0214027 C++ Note: df106 -238.649 -600.901 C++ Note: Exiting Regression C++ Note: df501 -76.71665 C++ Note: df504 0.6995155 0.3966929 Note: 5 strata used Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 0 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 322 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: derivs checked 1229.85 410.233 C++ Note: second derivs checked 3319.14 410.233 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 98.3613 91.6176 87.587 110.11 71.113 C++ Note: riskl checked 4.29942 3.84392 3.7452 4.59508 3.12621 C++ Note: df101 -79.5885 -79.5885 C++ Note: df102 5.42704 2.14202 C++ Note: df103 -7.11684 -6.21271 C++ Note: df104 -0.1 -0.1 C++ Note: df105 -0.762564 -0.34478 C++ Note: df106 -14.6652 -37.1559 C++ Note: Starting Halves C++ Note: df501 -79.58847 C++ Note: df504 -0.1 -0.1 C++ Note: values checked 0.471923 0.158585 C++ Note: sums checked 3109.21 3109.21 C++ Note: derivs checked 8604.8 1732.23 C++ Note: second derivs checked 31265.5 1732.23 C++ Note: dose checked 1000 C++ Note: non-dose checked 3109.21 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 3109.21 C++ Note: risk checked 3109.21 C++ Note: risk1 checked 8604.8 1732.23 C++ Note: risk2 checked 31265.5 1732.23 C++ Note: riskr checked 437.598 369.44 288.407 451.269 203.987 C++ Note: riskl checked 29.7555 18.4415 17.3204 19.7081 14.0257 C++ Note: df101 -77.1115 -77.1115 C++ Note: df102 1.6628 1.2965 C++ Note: df103 -7.18852 -6.1617 C++ Note: df104 0.471923 0.158585 C++ Note: df105 -0.231313 -0.210412 C++ Note: df106 -46.3745 -59.4767 C++ Note: df100 2456 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 437.598 369.44 288.407 451.269 203.987 C++ Note: riskl checked 29.7555 18.4415 17.3204 19.7081 14.0257 C++ Note: df101 -77.1115 -77.1115 C++ Note: df102 1.6628 1.2965 C++ Note: df103 -7.18852 -6.1617 C++ Note: df104 0.471923 0.158585 C++ Note: df105 -0.231313 -0.210412 C++ Note: df106 -46.3745 -59.4767 C++ Note: ending guess 0 C++ Note: df501 -77.11153 C++ Note: df504 0.4719227 0.1585847 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.4719227 0.1585847, -77.11153<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0.471923 0.158585 C++ Note: sums checked 3109.21 3109.21 C++ Note: derivs checked 8604.8 1732.23 C++ Note: second derivs checked 31265.5 1732.23 C++ Note: dose checked 1000 C++ Note: non-dose checked 3109.21 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 3109.21 C++ Note: risk checked 3109.21 C++ Note: risk1 checked 8604.8 1732.23 C++ Note: risk2 checked 31265.5 1732.23 C++ Note: Made Risk Side Lists C++ Note: riskr checked 437.598 369.44 288.407 451.269 203.987 C++ Note: riskl checked 29.7555 18.4415 17.3204 19.7081 14.0257 C++ Note: df101 -77.1115 -77.1115 C++ Note: df102 1.6628 1.2965 C++ Note: df103 -7.18852 -6.1617 C++ Note: df104 0.471923 0.158585 C++ Note: df105 -0.231313 -0.210412 C++ Note: df106 -46.3745 -59.4767 C++ Note: Starting Halves C++ Note: df501 -77.11153 C++ Note: df504 0.4719227 0.1585847 C++ Note: values checked 0.645408 0.316394 C++ Note: sums checked 5698.95 5698.95 C++ Note: derivs checked 18076.9 3359.94 C++ Note: second derivs checked 70503.7 3359.94 C++ Note: dose checked 1000 C++ Note: non-dose checked 5698.95 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 5698.95 C++ Note: risk checked 5698.95 C++ Note: risk1 checked 18076.9 3359.94 C++ Note: risk2 checked 70503.7 3359.94 C++ Note: riskr checked 866.381 621.431 461.192 794.093 330.167 C++ Note: riskl checked 63.0668 33.0727 31.2711 32.9428 26.3017 C++ Note: df101 -76.7689 -76.7689 C++ Note: df102 0.612277 0.54564 C++ Note: df103 -7.1484 -6.0464 C++ Note: df104 0.645408 0.316394 C++ Note: df105 -0.0856523 -0.0902421 C++ Note: df106 -125.383 -140.695 C++ Note: df100 5203 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 866.381 621.431 461.192 794.093 330.167 C++ Note: riskl checked 63.0668 33.0727 31.2711 32.9428 26.3017 C++ Note: df101 -76.7689 -76.7689 C++ Note: df102 0.612277 0.54564 C++ Note: df103 -7.1484 -6.0464 C++ Note: df104 0.645408 0.316394 C++ Note: df105 -0.0856523 -0.0902421 C++ Note: df106 -125.383 -140.695 C++ Note: riskr checked 866.381 621.431 461.192 794.093 330.167 C++ Note: riskl checked 63.0668 33.0727 31.2711 32.9428 26.3017 C++ Note: df101 -76.7689 -76.7689 C++ Note: df102 0.612277 0.54564 C++ Note: df103 -7.1484 -6.0464 C++ Note: df104 0.645408 0.316394 C++ Note: df105 -0.0856523 -0.0902421 C++ Note: df106 -125.383 -140.695 C++ Note: Exiting Regression C++ Note: df501 -76.76892 C++ Note: df504 0.6454076 0.316394 Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 0 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 231 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 -122.891 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -122.8909 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 -122.891 C++ Note: df104 -0.1 -0.1 C++ Note: df100 1134 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 -122.891 C++ Note: df104 -0.1 -0.1 C++ Note: df100 1570 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 -122.891 C++ Note: df104 -0.1 -0.1 C++ Note: ending guess 0 C++ Note: df501 -122.8909 C++ Note: df504 -0.1 -0.1 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1 -0.1, -122.8909<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 -122.891 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -122.8909 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 -122.891 C++ Note: df104 -0.1 -0.1 C++ Note: df100 2743 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 -122.891 C++ Note: df104 -0.1 -0.1 C++ Note: df100 3175 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 -122.891 C++ Note: df104 -0.1 -0.1 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 -122.891 C++ Note: df104 -0.1 -0.1 C++ Note: Exiting Regression C++ Note: df501 -122.8909 C++ Note: df504 -0.1 -0.1 Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 0 C++ Note: df99,25,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 237 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 -122.891 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -122.8909 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 -122.891 C++ Note: df104 -0.1 -0.1 C++ Note: df100 1110 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 -122.891 C++ Note: df104 -0.1 -0.1 C++ Note: df100 1544 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 -122.891 C++ Note: df104 -0.1 -0.1 C++ Note: ending guess 0 C++ Note: df501 -122.8909 C++ Note: df504 -0.1 -0.1 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1 -0.1, -122.8909<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 -122.891 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -122.8909 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 -122.891 C++ Note: df104 -0.1 -0.1 C++ Note: df100 2692 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 -122.891 C++ Note: df104 -0.1 -0.1 C++ Note: df100 3123 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 -122.891 C++ Note: df104 -0.1 -0.1 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 -122.891 C++ Note: df104 -0.1 -0.1 C++ Note: Exiting Regression C++ Note: df501 -122.8909 C++ Note: df504 -0.1 -0.1 Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 0 C++ Note: df99,25,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 177 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 -119.981 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -119.9814 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 -119.981 C++ Note: df104 -0.1 -0.1 C++ Note: df100 894 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 -119.981 C++ Note: df104 -0.1 -0.1 C++ Note: df100 1237 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 -119.981 C++ Note: df104 -0.1 -0.1 C++ Note: ending guess 0 C++ Note: df501 -119.9814 C++ Note: df504 -0.1 -0.1 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1 -0.1, -119.9814<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 -119.981 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -119.9814 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 -119.981 C++ Note: df104 -0.1 -0.1 C++ Note: df100 2135 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 -119.981 C++ Note: df104 -0.1 -0.1 C++ Note: df100 2474 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 -119.981 C++ Note: df104 -0.1 -0.1 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 -119.981 C++ Note: df104 -0.1 -0.1 C++ Note: Exiting Regression C++ Note: df501 -119.9814 C++ Note: df504 -0.1 -0.1 Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Term checked 0 0 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: Grouping Start C++ Note: df100 168 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 -119.981 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -119.9814 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 -119.981 C++ Note: df104 -0.1 -0.1 C++ Note: df100 859 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 -119.981 C++ Note: df104 -0.1 -0.1 C++ Note: df100 1202 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 -119.981 C++ Note: df104 -0.1 -0.1 C++ Note: ending guess 0 C++ Note: df501 -119.9814 C++ Note: df504 -0.1 -0.1 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1 -0.1, -119.9814<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 -119.981 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -119.9814 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 -119.981 C++ Note: df104 -0.1 -0.1 C++ Note: df100 2075 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 -119.981 C++ Note: df104 -0.1 -0.1 C++ Note: df100 2415 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:18 2024 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 -119.981 C++ Note: df104 -0.1 -0.1 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 -119.981 C++ Note: df104 -0.1 -0.1 C++ Note: Exiting Regression C++ Note: df501 -119.9814 C++ Note: df504 -0.1 -0.1 Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Term checked 0 0 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Grouping Start C++ Note: df100 230 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2197.44 C++ Note: risk1r checked 3174.27 1089.12 C++ Note: risk2r checked 7204.63 1089.12 C++ Note: riskl checked 19.6098 C++ Note: risk1l checked 42.0717 11.5472 C++ Note: risk2l checked 118.124 11.5472 C++ Note: df101 -122.891 -122.891 C++ Note: df102 21.2331 3.11507 C++ Note: df103 -19.7104 -6.49727 C++ Note: df104 -0.1 -0.1 C++ Note: df105 -1.07726 -0.479443 C++ Note: df106 -5.78769 -39.4505 C++ Note: Starting Halves C++ Note: df501 -122.8909 C++ Note: df504 -0.1 -0.1 C++ Note: values checked 0.732916 0.388699 C++ Note: sums checked 6380.99 1252.26 C++ Note: risk checked 7921.99 C++ Note: risk1 checked 26681.9 4784.79 C++ Note: risk2 checked 107491 4784.79 C++ Note: riskr checked 15672.9 C++ Note: risk1r checked 42701.5 9198.27 C++ Note: risk2r checked 144140 9198.27 C++ Note: riskl checked 259.026 C++ Note: risk1l checked 843.134 168.735 C++ Note: risk2l checked 3047.41 168.735 C++ Note: df101 -110.801 -110.801 C++ Note: df102 6.10212 0.649377 C++ Note: df103 -15.9738 -6.28124 C++ Note: df104 0.732916 0.388699 C++ Note: df105 -0.382009 -0.103384 C++ Note: df106 -18.1578 -170.627 C++ Note: df100 2608 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: riskr checked 15672.9 C++ Note: risk1r checked 42701.5 9198.27 C++ Note: risk2r checked 144140 9198.27 C++ Note: riskl checked 259.026 C++ Note: risk1l checked 843.134 168.735 C++ Note: risk2l checked 3047.41 168.735 C++ Note: df101 -110.801 -110.801 C++ Note: df102 6.10212 0.649377 C++ Note: df103 -15.9738 -6.28124 C++ Note: df104 0.732916 0.388699 C++ Note: df105 -0.382009 -0.103384 C++ Note: df106 -18.1578 -170.627 C++ Note: ending guess 0 C++ Note: df501 -110.8014 C++ Note: df504 0.732916 0.3886995 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.732916 0.3886995, -110.8014<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0.732916 0.388699 C++ Note: sums checked 6380.99 1252.26 C++ Note: risk checked 7921.99 C++ Note: risk1 checked 26681.9 4784.79 C++ Note: risk2 checked 107491 4784.79 C++ Note: Made Risk Side Lists C++ Note: riskr checked 15672.9 C++ Note: risk1r checked 42701.5 9198.27 C++ Note: risk2r checked 144140 9198.27 C++ Note: riskl checked 259.026 C++ Note: risk1l checked 843.134 168.735 C++ Note: risk2l checked 3047.41 168.735 C++ Note: df101 -110.801 -110.801 C++ Note: df102 6.10212 0.649377 C++ Note: df103 -15.9738 -6.28124 C++ Note: df104 0.732916 0.388699 C++ Note: df105 -0.382009 -0.103384 C++ Note: df106 -18.1578 -170.627 C++ Note: Starting Halves C++ Note: df501 -110.8014 C++ Note: df504 0.732916 0.3886995 C++ Note: values checked 1.02333 0.493704 C++ Note: sums checked 18600.8 1338.98 C++ Note: risk checked 24538.9 C++ Note: risk1 checked 97084.4 15240.1 C++ Note: risk2 checked 428953 15240.1 C++ Note: riskr checked 39636.5 C++ Note: risk1r checked 128036 24066.7 C++ Note: risk2r checked 480878 24066.7 C++ Note: riskl checked 745.302 C++ Note: risk1l checked 2645.43 469.387 C++ Note: risk2l checked 10112.8 469.387 C++ Note: df101 -109.621 -109.621 C++ Note: df102 1.83938 0.14137 C++ Note: df103 -13.8104 -6.17729 C++ Note: df104 1.02333 0.493704 C++ Note: df105 -0.133188 -0.0228854 C++ Note: df106 -59.5969 -775.422 C++ Note: df100 6021 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: riskr checked 39636.5 C++ Note: risk1r checked 128036 24066.7 C++ Note: risk2r checked 480878 24066.7 C++ Note: riskl checked 745.302 C++ Note: risk1l checked 2645.43 469.387 C++ Note: risk2l checked 10112.8 469.387 C++ Note: df101 -109.621 -109.621 C++ Note: df102 1.83938 0.14137 C++ Note: df103 -13.8104 -6.17729 C++ Note: df104 1.02333 0.493704 C++ Note: df105 -0.133188 -0.0228854 C++ Note: df106 -59.5969 -775.422 C++ Note: riskr checked 39636.5 C++ Note: risk1r checked 128036 24066.7 C++ Note: risk2r checked 480878 24066.7 C++ Note: riskl checked 745.302 C++ Note: risk1l checked 2645.43 469.387 C++ Note: risk2l checked 10112.8 469.387 C++ Note: df101 -109.621 -109.621 C++ Note: df102 1.83938 0.14137 C++ Note: df103 -13.8104 -6.17729 C++ Note: df104 1.02333 0.493704 C++ Note: df105 -0.133188 -0.0228854 C++ Note: df106 -59.5969 -775.422 C++ Note: Exiting Regression C++ Note: df501 -109.6211 C++ Note: df504 1.023328 0.4937042 Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Term checked 0 0 C++ Note: df99,25,Starting C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Grouping Start C++ Note: df100 288 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2197.44 C++ Note: risk1r checked 3174.27 1089.12 C++ Note: risk2r checked 7204.63 1089.12 C++ Note: riskl checked 19.6098 C++ Note: risk1l checked 42.0717 11.5472 C++ Note: risk2l checked 118.124 11.5472 C++ Note: df101 -122.891 -122.891 C++ Note: df102 21.2331 3.11507 C++ Note: df103 -19.7104 -6.49727 C++ Note: df104 -0.1 -0.1 C++ Note: df105 -1.07726 -0.479443 C++ Note: df106 -5.78769 -39.4505 C++ Note: Starting Halves C++ Note: df501 -122.8909 C++ Note: df504 -0.1 -0.1 C++ Note: values checked 0.707943 0.259582 C++ Note: sums checked 5868.37 1157.38 C++ Note: risk checked 6754.07 C++ Note: risk1 checked 22400.3 3873.99 C++ Note: risk2 checked 89482.9 3873.99 C++ Note: riskr checked 13607.5 C++ Note: risk1r checked 36518.1 7564.8 C++ Note: risk2r checked 122057 7564.8 C++ Note: riskl checked 219.94 C++ Note: risk1l checked 713.45 137.505 C++ Note: risk2l checked 2579.26 137.505 C++ Note: df101 -111.093 -111.093 C++ Note: df102 6.4244 1.45354 C++ Note: df103 -16.1091 -6.40177 C++ Note: df104 0.707943 0.259582 C++ Note: df105 -0.398805 -0.227053 C++ Note: df106 -17.2924 -76.4296 C++ Note: df100 2668 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: riskr checked 13607.5 C++ Note: risk1r checked 36518.1 7564.8 C++ Note: risk2r checked 122057 7564.8 C++ Note: riskl checked 219.94 C++ Note: risk1l checked 713.45 137.505 C++ Note: risk2l checked 2579.26 137.505 C++ Note: df101 -111.093 -111.093 C++ Note: df102 6.4244 1.45354 C++ Note: df103 -16.1091 -6.40177 C++ Note: df104 0.707943 0.259582 C++ Note: df105 -0.398805 -0.227053 C++ Note: df106 -17.2924 -76.4296 C++ Note: ending guess 0 C++ Note: df501 -111.0934 C++ Note: df504 0.7079435 0.259582 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.7079435 0.259582, -111.0934<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0.707943 0.259582 C++ Note: sums checked 5868.37 1157.38 C++ Note: risk checked 6754.07 C++ Note: risk1 checked 22400.3 3873.99 C++ Note: risk2 checked 89482.9 3873.99 C++ Note: Made Risk Side Lists C++ Note: riskr checked 13607.5 C++ Note: risk1r checked 36518.1 7564.8 C++ Note: risk2r checked 122057 7564.8 C++ Note: riskl checked 219.94 C++ Note: risk1l checked 713.45 137.505 C++ Note: risk2l checked 2579.26 137.505 C++ Note: df101 -111.093 -111.093 C++ Note: df102 6.4244 1.45354 C++ Note: df103 -16.1091 -6.40177 C++ Note: df104 0.707943 0.259582 C++ Note: df105 -0.398805 -0.227053 C++ Note: df106 -17.2924 -76.4296 C++ Note: Starting Halves C++ Note: df501 -111.0934 C++ Note: df504 0.7079435 0.259582 C++ Note: values checked 1.00705 0.429872 C++ Note: sums checked 17441.8 1285.18 C++ Note: risk checked 22129.4 C++ Note: risk1 checked 86917.6 13416 C++ Note: risk2 checked 382294 13416 C++ Note: riskr checked 36201.7 C++ Note: risk1r checked 115958 21431.5 C++ Note: risk2r checked 433026 21431.5 C++ Note: riskl checked 676.025 C++ Note: risk1l checked 2396.11 417.501 C++ Note: risk2l checked 9159.18 417.501 C++ Note: df101 -109.674 -109.674 C++ Note: df102 2.03825 0.531514 C++ Note: df103 -13.8822 -6.25712 C++ Note: df104 1.00705 0.429872 C++ Note: df105 -0.146825 -0.0849455 C++ Note: df106 -53.8081 -206.343 C++ Note: df100 6034 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: riskr checked 36201.7 C++ Note: risk1r checked 115958 21431.5 C++ Note: risk2r checked 433026 21431.5 C++ Note: riskl checked 676.025 C++ Note: risk1l checked 2396.11 417.501 C++ Note: risk2l checked 9159.18 417.501 C++ Note: df101 -109.674 -109.674 C++ Note: df102 2.03825 0.531514 C++ Note: df103 -13.8822 -6.25712 C++ Note: df104 1.00705 0.429872 C++ Note: df105 -0.146825 -0.0849455 C++ Note: df106 -53.8081 -206.343 C++ Note: riskr checked 36201.7 C++ Note: risk1r checked 115958 21431.5 C++ Note: risk2r checked 433026 21431.5 C++ Note: riskl checked 676.025 C++ Note: risk1l checked 2396.11 417.501 C++ Note: risk2l checked 9159.18 417.501 C++ Note: df101 -109.674 -109.674 C++ Note: df102 2.03825 0.531514 C++ Note: df103 -13.8822 -6.25712 C++ Note: df104 1.00705 0.429872 C++ Note: df105 -0.146825 -0.0849455 C++ Note: df106 -53.8081 -206.343 C++ Note: Exiting Regression C++ Note: df501 -109.6742 C++ Note: df504 1.007047 0.4298716 Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Term checked 0 0 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Grouping Start C++ Note: df100 239 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2125.36 C++ Note: risk1r checked 3418.73 1095.31 C++ Note: risk2r checked 8667.81 1095.31 C++ Note: riskl checked 19.6098 C++ Note: risk1l checked 42.0717 11.5472 C++ Note: risk2l checked 118.124 11.5472 C++ Note: df101 -119.981 -119.981 C++ Note: df102 6.06579 2.41134 C++ Note: df103 -8.60689 -6.47374 C++ Note: df104 -0.1 -0.1 C++ Note: df105 -0.70476 -0.37248 C++ Note: df106 -19.78 -49.7572 C++ Note: Starting Halves C++ Note: df501 -119.9814 C++ Note: df504 -0.1 -0.1 C++ Note: values checked 0.497478 0.312164 C++ Note: sums checked 3067.26 1194.55 C++ Note: risk checked 3648.05 C++ Note: risk1 checked 10299.6 2165.99 C++ Note: risk2 checked 37798.4 2165.99 C++ Note: riskr checked 9367.5 C++ Note: risk1r checked 24562.6 5580.77 C++ Note: risk2r checked 81557.6 5580.77 C++ Note: riskl checked 118.249 C++ Note: risk1l checked 351.472 78.443 C++ Note: risk2l checked 1199.14 78.443 C++ Note: df101 -117.142 -117.142 C++ Note: df102 1.31609 0.547704 C++ Note: df103 -9.05233 -6.2666 C++ Note: df104 0.497478 0.312164 C++ Note: df105 -0.145387 -0.0874005 C++ Note: df106 -89.0079 -213.879 C++ Note: df100 1587 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: riskr checked 9367.5 C++ Note: risk1r checked 24562.6 5580.77 C++ Note: risk2r checked 81557.6 5580.77 C++ Note: riskl checked 118.249 C++ Note: risk1l checked 351.472 78.443 C++ Note: risk2l checked 1199.14 78.443 C++ Note: df101 -117.142 -117.142 C++ Note: df102 1.31609 0.547704 C++ Note: df103 -9.05233 -6.2666 C++ Note: df104 0.497478 0.312164 C++ Note: df105 -0.145387 -0.0874005 C++ Note: df106 -89.0079 -213.879 C++ Note: ending guess 0 C++ Note: df501 -117.1424 C++ Note: df504 0.4974778 0.3121644 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.4974778 0.3121644, -117.1424<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0.497478 0.312164 C++ Note: sums checked 3067.26 1194.55 C++ Note: risk checked 3648.05 C++ Note: risk1 checked 10299.6 2165.99 C++ Note: risk2 checked 37798.4 2165.99 C++ Note: Made Risk Side Lists C++ Note: riskr checked 9367.5 C++ Note: risk1r checked 24562.6 5580.77 C++ Note: risk2r checked 81557.6 5580.77 C++ Note: riskl checked 118.249 C++ Note: risk1l checked 351.472 78.443 C++ Note: risk2l checked 1199.14 78.443 C++ Note: df101 -117.142 -117.142 C++ Note: df102 1.31609 0.547704 C++ Note: df103 -9.05233 -6.2666 C++ Note: df104 0.497478 0.312164 C++ Note: df105 -0.145387 -0.0874005 C++ Note: df106 -89.0079 -213.879 C++ Note: Starting Halves C++ Note: df501 -117.1424 C++ Note: df504 0.4974778 0.3121644 C++ Note: values checked 0.617144 0.398893 C++ Note: sums checked 4379.75 1260.28 C++ Note: risk checked 5479.95 C++ Note: risk1 checked 17006.9 3344.7 C++ Note: risk2 checked 65563.9 3344.7 C++ Note: riskr checked 13683.9 C++ Note: risk1r checked 38812.2 8366.11 C++ Note: risk2r checked 134810 8366.11 C++ Note: riskl checked 180.348 C++ Note: risk1l checked 561.69 120.669 C++ Note: risk2l checked 1971.73 120.669 C++ Note: df101 -117.015 -117.015 C++ Note: df102 0.320802 0.13496 C++ Note: df103 -9.12088 -6.18217 C++ Note: df104 0.617144 0.398893 C++ Note: df105 -0.0351723 -0.0218306 C++ Note: df106 -364.756 -867.031 C++ Note: df100 3414 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: riskr checked 13683.9 C++ Note: risk1r checked 38812.2 8366.11 C++ Note: risk2r checked 134810 8366.11 C++ Note: riskl checked 180.348 C++ Note: risk1l checked 561.69 120.669 C++ Note: risk2l checked 1971.73 120.669 C++ Note: df101 -117.015 -117.015 C++ Note: df102 0.320802 0.13496 C++ Note: df103 -9.12088 -6.18217 C++ Note: df104 0.617144 0.398893 C++ Note: df105 -0.0351723 -0.0218306 C++ Note: df106 -364.756 -867.031 C++ Note: riskr checked 13683.9 C++ Note: risk1r checked 38812.2 8366.11 C++ Note: risk2r checked 134810 8366.11 C++ Note: riskl checked 180.348 C++ Note: risk1l checked 561.69 120.669 C++ Note: risk2l checked 1971.73 120.669 C++ Note: df101 -117.015 -117.015 C++ Note: df102 0.320802 0.13496 C++ Note: df103 -9.12088 -6.18217 C++ Note: df104 0.617144 0.398893 C++ Note: df105 -0.0351723 -0.0218306 C++ Note: df106 -364.756 -867.031 C++ Note: Exiting Regression C++ Note: df501 -117.0147 C++ Note: df504 0.6171437 0.3988932 Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Term checked 0 0 C++ Note: df99,25,Starting C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Grouping Start C++ Note: df100 177 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 851.028 949.469 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2125.36 C++ Note: risk1r checked 3418.73 1095.31 C++ Note: risk2r checked 8667.81 1095.31 C++ Note: riskl checked 19.6098 C++ Note: risk1l checked 42.0717 11.5472 C++ Note: risk2l checked 118.124 11.5472 C++ Note: df101 -119.981 -119.981 C++ Note: df102 6.06579 2.41134 C++ Note: df103 -8.60689 -6.47374 C++ Note: df104 -0.1 -0.1 C++ Note: df105 -0.70476 -0.37248 C++ Note: df106 -19.78 -49.7572 C++ Note: Starting Halves C++ Note: df501 -119.9814 C++ Note: df504 -0.1 -0.1 C++ Note: values checked 0.42857 0.17936 C++ Note: sums checked 2537.47 1104.32 C++ Note: risk checked 2796.31 C++ Note: risk1 checked 7446.21 1576.41 C++ Note: risk2 checked 26529.4 1576.41 C++ Note: riskr checked 7268.45 C++ Note: risk1r checked 18181.7 4116.59 C++ Note: risk2r checked 58803.1 4116.59 C++ Note: riskl checked 88.5975 C++ Note: risk1l checked 256.339 56.699 C++ Note: risk2l checked 862.409 56.699 C++ Note: df101 -117.373 -117.373 C++ Note: df102 1.78502 1.30975 C++ Note: df103 -8.96103 -6.38772 C++ Note: df104 0.42857 0.17936 C++ Note: df105 -0.199199 -0.205041 C++ Note: df106 -65.7541 -89.6148 C++ Note: df100 1488 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: riskr checked 7268.45 C++ Note: risk1r checked 18181.7 4116.59 C++ Note: risk2r checked 58803.1 4116.59 C++ Note: riskl checked 88.5975 C++ Note: risk1l checked 256.339 56.699 C++ Note: risk2l checked 862.409 56.699 C++ Note: df101 -117.373 -117.373 C++ Note: df102 1.78502 1.30975 C++ Note: df103 -8.96103 -6.38772 C++ Note: df104 0.42857 0.17936 C++ Note: df105 -0.199199 -0.205041 C++ Note: df106 -65.7541 -89.6148 C++ Note: ending guess 0 C++ Note: df501 -117.3726 C++ Note: df504 0.4285697 0.17936 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.4285697 0.17936, -117.3726<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0.42857 0.17936 C++ Note: sums checked 2537.47 1104.32 C++ Note: risk checked 2796.31 C++ Note: risk1 checked 7446.21 1576.41 C++ Note: risk2 checked 26529.4 1576.41 C++ Note: Made Risk Side Lists C++ Note: riskr checked 7268.45 C++ Note: risk1r checked 18181.7 4116.59 C++ Note: risk2r checked 58803.1 4116.59 C++ Note: riskl checked 88.5975 C++ Note: risk1l checked 256.339 56.699 C++ Note: risk2l checked 862.409 56.699 C++ Note: df101 -117.373 -117.373 C++ Note: df102 1.78502 1.30975 C++ Note: df103 -8.96103 -6.38772 C++ Note: df104 0.42857 0.17936 C++ Note: df105 -0.199199 -0.205041 C++ Note: df106 -65.7541 -89.6148 C++ Note: Starting Halves C++ Note: df501 -117.3726 C++ Note: df504 0.4285697 0.17936 C++ Note: values checked 0.577969 0.333141 C++ Note: sums checked 3883.17 1209.93 C++ Note: risk checked 4672.1 C++ Note: risk1 checked 14081.1 2784.48 C++ Note: risk2 checked 53455.8 2784.48 C++ Note: riskr checked 11783.5 C++ Note: risk1r checked 32618.6 7038.87 C++ Note: risk2r checked 111717 7038.87 C++ Note: riskl checked 152.934 C++ Note: risk1l checked 470.041 100.807 C++ Note: risk2l checked 1638.11 100.807 C++ Note: df101 -117.054 -117.054 C++ Note: df102 0.609162 0.503449 C++ Note: df103 -9.07577 -6.25818 C++ Note: df104 0.577969 0.333141 C++ Note: df105 -0.0671196 -0.0804466 C++ Note: df106 -192.156 -232.504 C++ Note: df100 3320 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: riskr checked 11783.5 C++ Note: risk1r checked 32618.6 7038.87 C++ Note: risk2r checked 111717 7038.87 C++ Note: riskl checked 152.934 C++ Note: risk1l checked 470.041 100.807 C++ Note: risk2l checked 1638.11 100.807 C++ Note: df101 -117.054 -117.054 C++ Note: df102 0.609162 0.503449 C++ Note: df103 -9.07577 -6.25818 C++ Note: df104 0.577969 0.333141 C++ Note: df105 -0.0671196 -0.0804466 C++ Note: df106 -192.156 -232.504 C++ Note: riskr checked 11783.5 C++ Note: risk1r checked 32618.6 7038.87 C++ Note: risk2r checked 111717 7038.87 C++ Note: riskl checked 152.934 C++ Note: risk1l checked 470.041 100.807 C++ Note: risk2l checked 1638.11 100.807 C++ Note: df101 -117.054 -117.054 C++ Note: df102 0.609162 0.503449 C++ Note: df103 -9.07577 -6.25818 C++ Note: df104 0.577969 0.333141 C++ Note: df105 -0.0671196 -0.0804466 C++ Note: df106 -192.156 -232.504 C++ Note: Exiting Regression C++ Note: df501 -117.0539 C++ Note: df504 0.5779686 0.3331409 Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Term checked 0 0 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Grouping Start C++ Note: df100 232 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 0 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -122.8909 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 0 C++ Note: df104 -0.1 -0.1 C++ Note: df100 1191 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 0 C++ Note: df104 -0.1 -0.1 C++ Note: df100 1643 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 0 C++ Note: df104 -0.1 -0.1 C++ Note: ending guess 0 C++ Note: df501 -122.8909 C++ Note: df504 -0.1 -0.1 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1 -0.1, -122.8909<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 0 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -122.8909 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 0 C++ Note: df104 -0.1 -0.1 C++ Note: df100 2870 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 0 C++ Note: df104 -0.1 -0.1 C++ Note: df100 3318 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 0 C++ Note: df104 -0.1 -0.1 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 0 C++ Note: df104 -0.1 -0.1 C++ Note: Exiting Regression C++ Note: df501 -122.8909 C++ Note: df504 -0.1 -0.1 Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Term checked 0 0 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Grouping Start C++ Note: df100 230 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 0 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -122.8909 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 0 C++ Note: df104 -0.1 -0.1 C++ Note: df100 1164 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 0 C++ Note: df104 -0.1 -0.1 C++ Note: df100 1616 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 0 C++ Note: df104 -0.1 -0.1 C++ Note: ending guess 0 C++ Note: df501 -122.8909 C++ Note: df504 -0.1 -0.1 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1 -0.1, -122.8909<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 0 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -122.8909 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 0 C++ Note: df104 -0.1 -0.1 C++ Note: df100 2823 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 0 C++ Note: df104 -0.1 -0.1 C++ Note: df100 3274 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 0 C++ Note: df104 -0.1 -0.1 C++ Note: riskr checked 2197.44 C++ Note: riskl checked 19.6098 C++ Note: df101 -122.891 0 C++ Note: df104 -0.1 -0.1 C++ Note: Exiting Regression C++ Note: df501 -122.8909 C++ Note: df504 -0.1 -0.1 Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Term checked 0 0 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Grouping Start C++ Note: df100 302 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 0 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -119.9814 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 0 C++ Note: df104 -0.1 -0.1 C++ Note: df100 1075 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 0 C++ Note: df104 -0.1 -0.1 C++ Note: df100 1437 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 0 C++ Note: df104 -0.1 -0.1 C++ Note: ending guess 0 C++ Note: df501 -119.9814 C++ Note: df504 -0.1 -0.1 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1 -0.1, -119.9814<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 0 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -119.9814 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 0 C++ Note: df104 -0.1 -0.1 C++ Note: df100 2394 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 0 C++ Note: df104 -0.1 -0.1 C++ Note: df100 2751 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 0 C++ Note: df104 -0.1 -0.1 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 0 C++ Note: df104 -0.1 -0.1 C++ Note: Exiting Regression C++ Note: df501 -119.9814 C++ Note: df504 -0.1 -0.1 Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Term checked 0 0 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Grouping Start C++ Note: df100 193 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 0 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -119.9814 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 0 C++ Note: df104 -0.1 -0.1 C++ Note: df100 949 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 0 C++ Note: df104 -0.1 -0.1 C++ Note: ending guess 0 C++ Note: df501 -119.9814 C++ Note: df504 -0.1 -0.1 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1 -0.1, -119.9814<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 0 C++ Note: df104 -0.1 -0.1 C++ Note: Starting Halves C++ Note: df501 -119.9814 C++ Note: df504 -0.1 -0.1 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 0 C++ Note: df104 -0.1 -0.1 C++ Note: df100 1893 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 0 C++ Note: df104 -0.1 -0.1 C++ Note: df100 2254 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 0 C++ Note: df104 -0.1 -0.1 C++ Note: riskr checked 2125.36 C++ Note: riskl checked 19.6098 C++ Note: df101 -119.981 0 C++ Note: df104 -0.1 -0.1 C++ Note: Exiting Regression C++ Note: df501 -119.9814 C++ Note: df504 -0.1 -0.1 Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Term checked 0 0 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Grouping Start C++ Note: df100 241 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: derivs checked 1229.85 410.233 C++ Note: second derivs checked 3319.14 410.233 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2197.44 C++ Note: risk1r checked 3174.27 1089.12 C++ Note: risk2r checked 7204.63 1089.12 C++ Note: riskl checked 19.6098 C++ Note: risk1l checked 42.0717 11.5472 C++ Note: risk2l checked 118.124 11.5472 C++ Note: df101 -122.891 -122.891 C++ Note: df102 21.2331 3.11507 C++ Note: df103 -19.7104 -6.49727 C++ Note: df104 -0.1 -0.1 C++ Note: df105 -1.07726 -0.479443 C++ Note: df106 -5.78769 -39.4505 C++ Note: Starting Halves C++ Note: df501 -122.8909 C++ Note: df504 -0.1 -0.1 C++ Note: values checked 0.732916 0.388699 C++ Note: sums checked 7921.99 7921.99 C++ Note: derivs checked 26681.9 4784.79 C++ Note: second derivs checked 107491 4784.79 C++ Note: dose checked 1000 C++ Note: non-dose checked 7921.99 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 7921.99 C++ Note: risk checked 7921.99 C++ Note: risk1 checked 26681.9 4784.79 C++ Note: risk2 checked 107491 4784.79 C++ Note: riskr checked 15672.9 C++ Note: risk1r checked 42701.5 9198.27 C++ Note: risk2r checked 144140 9198.27 C++ Note: riskl checked 259.026 C++ Note: risk1l checked 843.134 168.735 C++ Note: risk2l checked 3047.41 168.735 C++ Note: df101 -110.801 -110.801 C++ Note: df102 6.10212 0.649377 C++ Note: df103 -15.9738 -6.28124 C++ Note: df104 0.732916 0.388699 C++ Note: df105 -0.382009 -0.103384 C++ Note: df106 -18.1578 -170.627 C++ Note: df100 3181 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: riskr checked 15672.9 C++ Note: risk1r checked 42701.5 9198.27 C++ Note: risk2r checked 144140 9198.27 C++ Note: riskl checked 259.026 C++ Note: risk1l checked 843.134 168.735 C++ Note: risk2l checked 3047.41 168.735 C++ Note: df101 -110.801 -110.801 C++ Note: df102 6.10212 0.649377 C++ Note: df103 -15.9738 -6.28124 C++ Note: df104 0.732916 0.388699 C++ Note: df105 -0.382009 -0.103384 C++ Note: df106 -18.1578 -170.627 C++ Note: ending guess 0 C++ Note: df501 -110.8014 C++ Note: df504 0.732916 0.3886995 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.732916 0.3886995, -110.8014<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0.732916 0.388699 C++ Note: sums checked 7921.99 7921.99 C++ Note: derivs checked 26681.9 4784.79 C++ Note: second derivs checked 107491 4784.79 C++ Note: dose checked 1000 C++ Note: non-dose checked 7921.99 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 7921.99 C++ Note: risk checked 7921.99 C++ Note: risk1 checked 26681.9 4784.79 C++ Note: risk2 checked 107491 4784.79 C++ Note: Made Risk Side Lists C++ Note: riskr checked 15672.9 C++ Note: risk1r checked 42701.5 9198.27 C++ Note: risk2r checked 144140 9198.27 C++ Note: riskl checked 259.026 C++ Note: risk1l checked 843.134 168.735 C++ Note: risk2l checked 3047.41 168.735 C++ Note: df101 -110.801 -110.801 C++ Note: df102 6.10212 0.649377 C++ Note: df103 -15.9738 -6.28124 C++ Note: df104 0.732916 0.388699 C++ Note: df105 -0.382009 -0.103384 C++ Note: df106 -18.1578 -170.627 C++ Note: Starting Halves C++ Note: df501 -110.8014 C++ Note: df504 0.732916 0.3886995 C++ Note: values checked 1.02333 0.493704 C++ Note: sums checked 24538.9 24538.9 C++ Note: derivs checked 97084.4 15240.1 C++ Note: second derivs checked 428953 15240.1 C++ Note: dose checked 1000 C++ Note: non-dose checked 24538.9 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 24538.9 C++ Note: risk checked 24538.9 C++ Note: risk1 checked 97084.4 15240.1 C++ Note: risk2 checked 428953 15240.1 C++ Note: riskr checked 39636.5 C++ Note: risk1r checked 128036 24066.7 C++ Note: risk2r checked 480878 24066.7 C++ Note: riskl checked 745.302 C++ Note: risk1l checked 2645.43 469.387 C++ Note: risk2l checked 10112.8 469.387 C++ Note: df101 -109.621 -109.621 C++ Note: df102 1.83938 0.14137 C++ Note: df103 -13.8104 -6.17729 C++ Note: df104 1.02333 0.493704 C++ Note: df105 -0.133188 -0.0228854 C++ Note: df106 -59.5969 -775.422 C++ Note: df100 7096 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: riskr checked 39636.5 C++ Note: risk1r checked 128036 24066.7 C++ Note: risk2r checked 480878 24066.7 C++ Note: riskl checked 745.302 C++ Note: risk1l checked 2645.43 469.387 C++ Note: risk2l checked 10112.8 469.387 C++ Note: df101 -109.621 -109.621 C++ Note: df102 1.83938 0.14137 C++ Note: df103 -13.8104 -6.17729 C++ Note: df104 1.02333 0.493704 C++ Note: df105 -0.133188 -0.0228854 C++ Note: df106 -59.5969 -775.422 C++ Note: riskr checked 39636.5 C++ Note: risk1r checked 128036 24066.7 C++ Note: risk2r checked 480878 24066.7 C++ Note: riskl checked 745.302 C++ Note: risk1l checked 2645.43 469.387 C++ Note: risk2l checked 10112.8 469.387 C++ Note: df101 -109.621 -109.621 C++ Note: df102 1.83938 0.14137 C++ Note: df103 -13.8104 -6.17729 C++ Note: df104 1.02333 0.493704 C++ Note: df105 -0.133188 -0.0228854 C++ Note: df106 -59.5969 -775.422 C++ Note: Exiting Regression C++ Note: df501 -109.6211 C++ Note: df504 1.023328 0.4937042 Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Term checked 0 0 C++ Note: df99,26,Starting C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Grouping Start C++ Note: df100 236 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: derivs checked 1229.85 410.233 C++ Note: second derivs checked 3319.14 410.233 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2197.44 C++ Note: risk1r checked 3174.27 1089.12 C++ Note: risk2r checked 7204.63 1089.12 C++ Note: riskl checked 19.6098 C++ Note: risk1l checked 42.0717 11.5472 C++ Note: risk2l checked 118.124 11.5472 C++ Note: df101 -122.891 -122.891 C++ Note: df102 21.2331 3.11507 C++ Note: df103 -19.7104 -6.49727 C++ Note: df104 -0.1 -0.1 C++ Note: df105 -1.07726 -0.479443 C++ Note: df106 -5.78769 -39.4505 C++ Note: Starting Halves C++ Note: df501 -122.8909 C++ Note: df504 -0.1 -0.1 C++ Note: values checked 0.707943 0.259582 C++ Note: sums checked 6754.07 6754.07 C++ Note: derivs checked 22400.3 3873.99 C++ Note: second derivs checked 89482.9 3873.99 C++ Note: dose checked 1000 C++ Note: non-dose checked 6754.07 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 6754.07 C++ Note: risk checked 6754.07 C++ Note: risk1 checked 22400.3 3873.99 C++ Note: risk2 checked 89482.9 3873.99 C++ Note: riskr checked 13607.5 C++ Note: risk1r checked 36518.1 7564.8 C++ Note: risk2r checked 122057 7564.8 C++ Note: riskl checked 219.94 C++ Note: risk1l checked 713.45 137.505 C++ Note: risk2l checked 2579.26 137.505 C++ Note: df101 -111.093 -111.093 C++ Note: df102 6.4244 1.45354 C++ Note: df103 -16.1091 -6.40177 C++ Note: df104 0.707943 0.259582 C++ Note: df105 -0.398805 -0.227053 C++ Note: df106 -17.2924 -76.4296 C++ Note: df100 3128 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: riskr checked 13607.5 C++ Note: risk1r checked 36518.1 7564.8 C++ Note: risk2r checked 122057 7564.8 C++ Note: riskl checked 219.94 C++ Note: risk1l checked 713.45 137.505 C++ Note: risk2l checked 2579.26 137.505 C++ Note: df101 -111.093 -111.093 C++ Note: df102 6.4244 1.45354 C++ Note: df103 -16.1091 -6.40177 C++ Note: df104 0.707943 0.259582 C++ Note: df105 -0.398805 -0.227053 C++ Note: df106 -17.2924 -76.4296 C++ Note: ending guess 0 C++ Note: df501 -111.0934 C++ Note: df504 0.7079435 0.259582 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.7079435 0.259582, -111.0934<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0.707943 0.259582 C++ Note: sums checked 6754.07 6754.07 C++ Note: derivs checked 22400.3 3873.99 C++ Note: second derivs checked 89482.9 3873.99 C++ Note: dose checked 1000 C++ Note: non-dose checked 6754.07 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 6754.07 C++ Note: risk checked 6754.07 C++ Note: risk1 checked 22400.3 3873.99 C++ Note: risk2 checked 89482.9 3873.99 C++ Note: Made Risk Side Lists C++ Note: riskr checked 13607.5 C++ Note: risk1r checked 36518.1 7564.8 C++ Note: risk2r checked 122057 7564.8 C++ Note: riskl checked 219.94 C++ Note: risk1l checked 713.45 137.505 C++ Note: risk2l checked 2579.26 137.505 C++ Note: df101 -111.093 -111.093 C++ Note: df102 6.4244 1.45354 C++ Note: df103 -16.1091 -6.40177 C++ Note: df104 0.707943 0.259582 C++ Note: df105 -0.398805 -0.227053 C++ Note: df106 -17.2924 -76.4296 C++ Note: Starting Halves C++ Note: df501 -111.0934 C++ Note: df504 0.7079435 0.259582 C++ Note: values checked 1.00705 0.429872 C++ Note: sums checked 22129.4 22129.4 C++ Note: derivs checked 86917.6 13416 C++ Note: second derivs checked 382294 13416 C++ Note: dose checked 1000 C++ Note: non-dose checked 22129.4 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 22129.4 C++ Note: risk checked 22129.4 C++ Note: risk1 checked 86917.6 13416 C++ Note: risk2 checked 382294 13416 C++ Note: riskr checked 36201.7 C++ Note: risk1r checked 115958 21431.5 C++ Note: risk2r checked 433026 21431.5 C++ Note: riskl checked 676.025 C++ Note: risk1l checked 2396.11 417.501 C++ Note: risk2l checked 9159.18 417.501 C++ Note: df101 -109.674 -109.674 C++ Note: df102 2.03825 0.531514 C++ Note: df103 -13.8822 -6.25712 C++ Note: df104 1.00705 0.429872 C++ Note: df105 -0.146825 -0.0849455 C++ Note: df106 -53.8081 -206.343 C++ Note: df100 7040 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: riskr checked 36201.7 C++ Note: risk1r checked 115958 21431.5 C++ Note: risk2r checked 433026 21431.5 C++ Note: riskl checked 676.025 C++ Note: risk1l checked 2396.11 417.501 C++ Note: risk2l checked 9159.18 417.501 C++ Note: df101 -109.674 -109.674 C++ Note: df102 2.03825 0.531514 C++ Note: df103 -13.8822 -6.25712 C++ Note: df104 1.00705 0.429872 C++ Note: df105 -0.146825 -0.0849455 C++ Note: df106 -53.8081 -206.343 C++ Note: riskr checked 36201.7 C++ Note: risk1r checked 115958 21431.5 C++ Note: risk2r checked 433026 21431.5 C++ Note: riskl checked 676.025 C++ Note: risk1l checked 2396.11 417.501 C++ Note: risk2l checked 9159.18 417.501 C++ Note: df101 -109.674 -109.674 C++ Note: df102 2.03825 0.531514 C++ Note: df103 -13.8822 -6.25712 C++ Note: df104 1.00705 0.429872 C++ Note: df105 -0.146825 -0.0849455 C++ Note: df106 -53.8081 -206.343 C++ Note: Exiting Regression C++ Note: df501 -109.6742 C++ Note: df504 1.007047 0.4298716 Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Term checked 0 0 C++ Note: df99,25,Starting C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Grouping Start C++ Note: df100 181 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: derivs checked 1229.85 410.233 C++ Note: second derivs checked 3319.14 410.233 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2125.36 C++ Note: risk1r checked 3418.73 1095.31 C++ Note: risk2r checked 8667.81 1095.31 C++ Note: riskl checked 19.6098 C++ Note: risk1l checked 42.0717 11.5472 C++ Note: risk2l checked 118.124 11.5472 C++ Note: df101 -119.981 -119.981 C++ Note: df102 6.06579 2.41134 C++ Note: df103 -8.60689 -6.47374 C++ Note: df104 -0.1 -0.1 C++ Note: df105 -0.70476 -0.37248 C++ Note: df106 -19.78 -49.7572 C++ Note: Starting Halves C++ Note: df501 -119.9814 C++ Note: df504 -0.1 -0.1 C++ Note: values checked 0.497478 0.312164 C++ Note: sums checked 3648.05 3648.05 C++ Note: derivs checked 10299.6 2165.99 C++ Note: second derivs checked 37798.4 2165.99 C++ Note: dose checked 1000 C++ Note: non-dose checked 3648.05 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 3648.05 C++ Note: risk checked 3648.05 C++ Note: risk1 checked 10299.6 2165.99 C++ Note: risk2 checked 37798.4 2165.99 C++ Note: riskr checked 9367.5 C++ Note: risk1r checked 24562.6 5580.77 C++ Note: risk2r checked 81557.6 5580.77 C++ Note: riskl checked 118.249 C++ Note: risk1l checked 351.472 78.443 C++ Note: risk2l checked 1199.14 78.443 C++ Note: df101 -117.142 -117.142 C++ Note: df102 1.31609 0.547704 C++ Note: df103 -9.05233 -6.2666 C++ Note: df104 0.497478 0.312164 C++ Note: df105 -0.145387 -0.0874005 C++ Note: df106 -89.0079 -213.879 C++ Note: df100 2066 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: riskr checked 9367.5 C++ Note: risk1r checked 24562.6 5580.77 C++ Note: risk2r checked 81557.6 5580.77 C++ Note: riskl checked 118.249 C++ Note: risk1l checked 351.472 78.443 C++ Note: risk2l checked 1199.14 78.443 C++ Note: df101 -117.142 -117.142 C++ Note: df102 1.31609 0.547704 C++ Note: df103 -9.05233 -6.2666 C++ Note: df104 0.497478 0.312164 C++ Note: df105 -0.145387 -0.0874005 C++ Note: df106 -89.0079 -213.879 C++ Note: ending guess 0 C++ Note: df501 -117.1424 C++ Note: df504 0.4974778 0.3121644 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.4974778 0.3121644, -117.1424<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0.497478 0.312164 C++ Note: sums checked 3648.05 3648.05 C++ Note: derivs checked 10299.6 2165.99 C++ Note: second derivs checked 37798.4 2165.99 C++ Note: dose checked 1000 C++ Note: non-dose checked 3648.05 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 3648.05 C++ Note: risk checked 3648.05 C++ Note: risk1 checked 10299.6 2165.99 C++ Note: risk2 checked 37798.4 2165.99 C++ Note: Made Risk Side Lists C++ Note: riskr checked 9367.5 C++ Note: risk1r checked 24562.6 5580.77 C++ Note: risk2r checked 81557.6 5580.77 C++ Note: riskl checked 118.249 C++ Note: risk1l checked 351.472 78.443 C++ Note: risk2l checked 1199.14 78.443 C++ Note: df101 -117.142 -117.142 C++ Note: df102 1.31609 0.547704 C++ Note: df103 -9.05233 -6.2666 C++ Note: df104 0.497478 0.312164 C++ Note: df105 -0.145387 -0.0874005 C++ Note: df106 -89.0079 -213.879 C++ Note: Starting Halves C++ Note: df501 -117.1424 C++ Note: df504 0.4974778 0.3121644 C++ Note: values checked 0.617144 0.398893 C++ Note: sums checked 5479.95 5479.95 C++ Note: derivs checked 17006.9 3344.7 C++ Note: second derivs checked 65563.9 3344.7 C++ Note: dose checked 1000 C++ Note: non-dose checked 5479.95 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 5479.95 C++ Note: risk checked 5479.95 C++ Note: risk1 checked 17006.9 3344.7 C++ Note: risk2 checked 65563.9 3344.7 C++ Note: riskr checked 13683.9 C++ Note: risk1r checked 38812.2 8366.11 C++ Note: risk2r checked 134810 8366.11 C++ Note: riskl checked 180.348 C++ Note: risk1l checked 561.69 120.669 C++ Note: risk2l checked 1971.73 120.669 C++ Note: df101 -117.015 -117.015 C++ Note: df102 0.320802 0.13496 C++ Note: df103 -9.12088 -6.18217 C++ Note: df104 0.617144 0.398893 C++ Note: df105 -0.0351723 -0.0218306 C++ Note: df106 -364.756 -867.031 C++ Note: df100 4453 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: riskr checked 13683.9 C++ Note: risk1r checked 38812.2 8366.11 C++ Note: risk2r checked 134810 8366.11 C++ Note: riskl checked 180.348 C++ Note: risk1l checked 561.69 120.669 C++ Note: risk2l checked 1971.73 120.669 C++ Note: df101 -117.015 -117.015 C++ Note: df102 0.320802 0.13496 C++ Note: df103 -9.12088 -6.18217 C++ Note: df104 0.617144 0.398893 C++ Note: df105 -0.0351723 -0.0218306 C++ Note: df106 -364.756 -867.031 C++ Note: riskr checked 13683.9 C++ Note: risk1r checked 38812.2 8366.11 C++ Note: risk2r checked 134810 8366.11 C++ Note: riskl checked 180.348 C++ Note: risk1l checked 561.69 120.669 C++ Note: risk2l checked 1971.73 120.669 C++ Note: df101 -117.015 -117.015 C++ Note: df102 0.320802 0.13496 C++ Note: df103 -9.12088 -6.18217 C++ Note: df104 0.617144 0.398893 C++ Note: df105 -0.0351723 -0.0218306 C++ Note: df106 -364.756 -867.031 C++ Note: Exiting Regression C++ Note: df501 -117.0147 C++ Note: df504 0.6171437 0.3988932 Note: 26 risk groups C++ Note: START_COX_GUESS C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Term checked 0 0 C++ Note: df99,25,Starting C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Grouping Start C++ Note: df100 178 0 0 -1,Prep_List C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: starting subterms 1 in guess 0 C++ Note: values checked -0.1 -0.1 C++ Note: sums checked 807.883 807.883 C++ Note: derivs checked 1229.85 410.233 C++ Note: second derivs checked 3319.14 410.233 C++ Note: dose checked 1000 C++ Note: non-dose checked 807.883 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 807.883 C++ Note: risk checked 807.883 C++ Note: risk1 checked 1229.85 410.233 C++ Note: risk2 checked 3319.14 410.233 C++ Note: Made Risk Side Lists C++ Note: riskr checked 2125.36 C++ Note: risk1r checked 3418.73 1095.31 C++ Note: risk2r checked 8667.81 1095.31 C++ Note: riskl checked 19.6098 C++ Note: risk1l checked 42.0717 11.5472 C++ Note: risk2l checked 118.124 11.5472 C++ Note: df101 -119.981 -119.981 C++ Note: df102 6.06579 2.41134 C++ Note: df103 -8.60689 -6.47374 C++ Note: df104 -0.1 -0.1 C++ Note: df105 -0.70476 -0.37248 C++ Note: df106 -19.78 -49.7572 C++ Note: Starting Halves C++ Note: df501 -119.9814 C++ Note: df504 -0.1 -0.1 C++ Note: values checked 0.42857 0.17936 C++ Note: sums checked 2796.31 2796.31 C++ Note: derivs checked 7446.21 1576.41 C++ Note: second derivs checked 26529.4 1576.41 C++ Note: dose checked 1000 C++ Note: non-dose checked 2796.31 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 2796.31 C++ Note: risk checked 2796.31 C++ Note: risk1 checked 7446.21 1576.41 C++ Note: risk2 checked 26529.4 1576.41 C++ Note: riskr checked 7268.45 C++ Note: risk1r checked 18181.7 4116.59 C++ Note: risk2r checked 58803.1 4116.59 C++ Note: riskl checked 88.5975 C++ Note: risk1l checked 256.339 56.699 C++ Note: risk2l checked 862.409 56.699 C++ Note: df101 -117.373 -117.373 C++ Note: df102 1.78502 1.30975 C++ Note: df103 -8.96103 -6.38772 C++ Note: df104 0.42857 0.17936 C++ Note: df105 -0.199199 -0.205041 C++ Note: df106 -65.7541 -89.6148 C++ Note: df100 2191 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: riskr checked 7268.45 C++ Note: risk1r checked 18181.7 4116.59 C++ Note: risk2r checked 58803.1 4116.59 C++ Note: riskl checked 88.5975 C++ Note: risk1l checked 256.339 56.699 C++ Note: risk2l checked 862.409 56.699 C++ Note: df101 -117.373 -117.373 C++ Note: df102 1.78502 1.30975 C++ Note: df103 -8.96103 -6.38772 C++ Note: df104 0.42857 0.17936 C++ Note: df105 -0.199199 -0.205041 C++ Note: df106 -65.7541 -89.6148 C++ Note: ending guess 0 C++ Note: df501 -117.3726 C++ Note: df504 0.4285697 0.17936 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.4285697 0.17936, -117.3726<-- Best Guess C++ Note: starting subterms 1 in best guess 0 C++ Note: values checked 0.42857 0.17936 C++ Note: sums checked 2796.31 2796.31 C++ Note: derivs checked 7446.21 1576.41 C++ Note: second derivs checked 26529.4 1576.41 C++ Note: dose checked 1000 C++ Note: non-dose checked 2796.31 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 2796.31 C++ Note: risk checked 2796.31 C++ Note: risk1 checked 7446.21 1576.41 C++ Note: risk2 checked 26529.4 1576.41 C++ Note: Made Risk Side Lists C++ Note: riskr checked 7268.45 C++ Note: risk1r checked 18181.7 4116.59 C++ Note: risk2r checked 58803.1 4116.59 C++ Note: riskl checked 88.5975 C++ Note: risk1l checked 256.339 56.699 C++ Note: risk2l checked 862.409 56.699 C++ Note: df101 -117.373 -117.373 C++ Note: df102 1.78502 1.30975 C++ Note: df103 -8.96103 -6.38772 C++ Note: df104 0.42857 0.17936 C++ Note: df105 -0.199199 -0.205041 C++ Note: df106 -65.7541 -89.6148 C++ Note: Starting Halves C++ Note: df501 -117.3726 C++ Note: df504 0.4285697 0.17936 C++ Note: values checked 0.577969 0.333141 C++ Note: sums checked 4672.1 4672.1 C++ Note: derivs checked 14081.1 2784.48 C++ Note: second derivs checked 53455.8 2784.48 C++ Note: dose checked 1000 C++ Note: non-dose checked 4672.1 C++ Note: LIN_non-dose checked 1000 C++ Note: PLIN_non-dose checked 1000 C++ Note: LOGLIN_non-dose checked 4672.1 C++ Note: risk checked 4672.1 C++ Note: risk1 checked 14081.1 2784.48 C++ Note: risk2 checked 53455.8 2784.48 C++ Note: riskr checked 11783.5 C++ Note: risk1r checked 32618.6 7038.87 C++ Note: risk2r checked 111717 7038.87 C++ Note: riskl checked 152.934 C++ Note: risk1l checked 470.041 100.807 C++ Note: risk2l checked 1638.11 100.807 C++ Note: df101 -117.054 -117.054 C++ Note: df102 0.609162 0.503449 C++ Note: df103 -9.07577 -6.25818 C++ Note: df104 0.577969 0.333141 C++ Note: df105 -0.0671196 -0.0804466 C++ Note: df106 -192.156 -232.504 C++ Note: df100 4546 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: riskr checked 11783.5 C++ Note: risk1r checked 32618.6 7038.87 C++ Note: risk2r checked 111717 7038.87 C++ Note: riskl checked 152.934 C++ Note: risk1l checked 470.041 100.807 C++ Note: risk2l checked 1638.11 100.807 C++ Note: df101 -117.054 -117.054 C++ Note: df102 0.609162 0.503449 C++ Note: df103 -9.07577 -6.25818 C++ Note: df104 0.577969 0.333141 C++ Note: df105 -0.0671196 -0.0804466 C++ Note: df106 -192.156 -232.504 C++ Note: riskr checked 11783.5 C++ Note: risk1r checked 32618.6 7038.87 C++ Note: risk2r checked 111717 7038.87 C++ Note: riskl checked 152.934 C++ Note: risk1l checked 470.041 100.807 C++ Note: risk2l checked 1638.11 100.807 C++ Note: df101 -117.054 -117.054 C++ Note: df102 0.609162 0.503449 C++ Note: df103 -9.07577 -6.25818 C++ Note: df104 0.577969 0.333141 C++ Note: df105 -0.0671196 -0.0804466 C++ Note: df106 -192.156 -232.504 C++ Note: Exiting Regression C++ Note: df501 -117.0539 C++ Note: df504 0.5779686 0.3331409 Warning: model covariate order changed C++ Note: START_POIS_GUESS C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Term checked 0 1 2 C++ Note: df99,32,Starting C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: starting subterms 3 in guess 0 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 135.17 C++ Note: df101 -467.661 -467.661 -467.661 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 707.321 C++ Note: Starting Halves C++ Note: df501 -467.6607 C++ Note: df504 0.1 0.1 0.01 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 135.17 C++ Note: df101 -467.661 -467.661 -467.661 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 707.321 C++ Note: df100 1511 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 135.17 C++ Note: df101 -467.661 -467.661 -467.661 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 707.321 C++ Note: df100 2052 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 135.17 C++ Note: df101 -467.661 -467.661 -467.661 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 707.321 C++ Note: df100 2603 3 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 135.17 C++ Note: df101 -467.661 -467.661 -467.661 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 707.321 C++ Note: df100 3154 4 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 135.17 C++ Note: df101 -467.661 -467.661 -467.661 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 707.321 C++ Note: df100 3729 5 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df100 3780 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df101 -467.6607 -467.6607 -467.6607 C++ Note: df104 0.1 0.1 0.01 C++ Note: df101 -467.661 -467.661 -467.661 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 707.321 C++ Note: ending guess 0 C++ Note: df501 -467.6607 C++ Note: df504 0.1 0.1 0.01 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.1 0.1 0.01, -467.6607<-- Best Guess C++ Note: starting subterms 3 in best guess 0 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 135.17 C++ Note: Made Risk Side Lists C++ Note: df101 -467.661 -467.661 -467.661 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 707.321 C++ Note: Starting Halves C++ Note: df501 -467.6607 C++ Note: df504 0.1 0.1 0.01 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 135.17 C++ Note: df101 -467.661 -467.661 -467.661 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 707.321 C++ Note: df100 5246 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 135.17 C++ Note: df101 -467.661 -467.661 -467.661 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 707.321 C++ Note: df100 5788 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 135.17 C++ Note: df101 -467.661 -467.661 -467.661 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 707.321 C++ Note: df100 6336 3 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 135.17 C++ Note: df101 -467.661 -467.661 -467.661 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 707.321 C++ Note: df100 6848 4 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 135.17 C++ Note: df101 -467.661 -467.661 -467.661 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 707.321 C++ Note: df100 7368 5 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df100 7418 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df101 -467.6607 -467.6607 -467.6607 C++ Note: df104 0.1 0.1 0.01 C++ Note: df101 -467.661 -467.661 -467.661 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 707.321 C++ Note: df501 -467.6607 C++ Note: df504 0.1 0.1 0.01 Warning: model covariate order changed C++ Note: START_POIS_GUESS C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Term checked 0 1 2 C++ Note: df99,30,Starting C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: starting subterms 3 in guess 0 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 116.849 C++ Note: df101 -463.51 -463.51 -463.51 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 699.02 C++ Note: Starting Halves C++ Note: df501 -463.5098 C++ Note: df504 0.1 0.1 0.01 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 116.849 C++ Note: df101 -463.51 -463.51 -463.51 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 699.02 C++ Note: df100 1382 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 116.849 C++ Note: df101 -463.51 -463.51 -463.51 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 699.02 C++ Note: df100 1985 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 116.849 C++ Note: df101 -463.51 -463.51 -463.51 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 699.02 C++ Note: df100 2543 3 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 116.849 C++ Note: df101 -463.51 -463.51 -463.51 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 699.02 C++ Note: df100 3142 4 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 116.849 C++ Note: df101 -463.51 -463.51 -463.51 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 699.02 C++ Note: df100 3669 5 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df100 3716 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df101 -463.5098 -463.5098 -463.5098 C++ Note: df104 0.1 0.1 0.01 C++ Note: df101 -463.51 -463.51 -463.51 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 699.02 C++ Note: ending guess 0 C++ Note: df501 -463.5098 C++ Note: df504 0.1 0.1 0.01 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.1 0.1 0.01, -463.5098<-- Best Guess C++ Note: starting subterms 3 in best guess 0 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 116.849 C++ Note: Made Risk Side Lists C++ Note: df101 -463.51 -463.51 -463.51 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 699.02 C++ Note: Starting Halves C++ Note: df501 -463.5098 C++ Note: df504 0.1 0.1 0.01 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 116.849 C++ Note: df101 -463.51 -463.51 -463.51 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 699.02 C++ Note: df100 5166 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 116.849 C++ Note: df101 -463.51 -463.51 -463.51 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 699.02 C++ Note: df100 5881 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 116.849 C++ Note: df101 -463.51 -463.51 -463.51 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 699.02 C++ Note: df100 6402 3 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 116.849 C++ Note: df101 -463.51 -463.51 -463.51 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 699.02 C++ Note: df100 7030 4 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 116.849 C++ Note: df101 -463.51 -463.51 -463.51 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 699.02 C++ Note: df100 7583 5 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df100 7630 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df101 -463.5098 -463.5098 -463.5098 C++ Note: df104 0.1 0.1 0.01 C++ Note: df101 -463.51 -463.51 -463.51 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 699.02 C++ Note: df501 -463.5098 C++ Note: df504 0.1 0.1 0.01 Warning: model covariate order changed C++ Note: START_POIS_GUESS C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Term checked 0 1 2 C++ Note: df99,30,Starting C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: starting subterms 3 in guess 0 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: derivs checked 2662.16 2662.16 1673.67 C++ Note: second derivs checked 8088.51 8088.51 4753.83 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 135.17 C++ Note: risk1 checked 302.14 121.78 68.7623 C++ Note: risk2 checked 928.77 380.955 194.839 C++ Note: df101 -467.661 -467.661 -467.661 C++ Note: df102 -94.3101 -39.4194 -9.93487 C++ Note: df103 -1040.45 -259.573 -93.8514 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 707.321 C++ Note: df105 0.0906437 0.151862 0.105857 C++ Note: df106 4.95875 11.8637 47.0727 C++ Note: Starting Halves C++ Note: df501 -467.6607 C++ Note: df504 0.1 0.1 0.01 C++ Note: values checked 0.0320172 -0.0138968 -0.0693931 C++ Note: sums checked 1066.29 973.12 897.344 C++ Note: derivs checked 2170.09 1895.1 1342.81 C++ Note: second derivs checked 6452.98 5549.74 3636.92 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1066.29 973.12 897.344 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1066.29 973.12 897.344 C++ Note: risk checked 102.86 C++ Note: risk1 checked 208.566 69.9862 48.0225 C++ Note: risk2 checked 619.655 207.132 129.963 C++ Note: df101 -463.451 -463.451 -463.451 C++ Note: df102 10.3802 4.17009 9.3252 C++ Note: df103 -694.198 -76.4056 -27.9422 C++ Note: df104 0.0320172 -0.0138968 -0.0693931 C++ Note: Checking Deviance 698.903 C++ Note: df105 -0.0149527 -0.0545783 -0.333732 C++ Note: df106 -44.6478 -111.137 -49.6988 C++ Note: df100 2548 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df100 2596 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df101 -463.4514 -463.4514 -463.4514 C++ Note: df102 10.38017 4.170085 9.325204 C++ Note: df103 -694.1983 -76.40556 -27.94216 C++ Note: df104 0.03201725 -0.01389683 -0.06939307 C++ Note: Checking Deviance 698.9028 C++ Note: df105 -0.01495275 -0.05457829 -0.3337324 C++ Note: df106 -44.64776 -111.1372 -49.69879 C++ Note: df101 -463.451 -463.451 -463.451 C++ Note: df102 10.3802 4.17009 9.3252 C++ Note: df103 -694.198 -76.4056 -27.9422 C++ Note: df104 0.0320172 -0.0138968 -0.0693931 C++ Note: Checking Deviance 698.903 C++ Note: df105 -0.0149527 -0.0545783 -0.333732 C++ Note: df106 -44.6478 -111.137 -49.6988 C++ Note: ending guess 0 C++ Note: df501 -463.4514 C++ Note: df504 0.03201725 -0.01389683 -0.06939307 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.03201725 -0.01389683 -0.06939307, -463.4514<-- Best Guess C++ Note: starting subterms 3 in best guess 0 C++ Note: values checked 0.0320172 -0.0138968 -0.0693931 C++ Note: sums checked 1066.29 973.12 897.344 C++ Note: derivs checked 2170.09 1895.1 1342.81 C++ Note: second derivs checked 6452.98 5549.74 3636.92 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1066.29 973.12 897.344 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1066.29 973.12 897.344 C++ Note: risk checked 102.86 C++ Note: risk1 checked 208.566 69.9862 48.0225 C++ Note: risk2 checked 619.655 207.132 129.963 C++ Note: Made Risk Side Lists C++ Note: df101 -463.451 -463.451 -463.451 C++ Note: df102 10.3802 4.17009 9.3252 C++ Note: df103 -694.198 -76.4056 -27.9422 C++ Note: df104 0.0320172 -0.0138968 -0.0693931 C++ Note: Checking Deviance 698.903 C++ Note: df105 -0.0149527 -0.0545783 -0.333732 C++ Note: df106 -44.6478 -111.137 -49.6988 C++ Note: Starting Halves C++ Note: df501 -463.4514 C++ Note: df504 0.03201725 -0.01389683 -0.06939307 C++ Note: values checked 0.0432318 0.0270369 0.180906 C++ Note: sums checked 1091.03 1055.56 1388.12 C++ Note: derivs checked 2243.81 2138.21 2787.22 C++ Note: second derivs checked 6696.56 6347.84 8719.98 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1091.03 1055.56 1388.12 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1091.03 1055.56 1388.12 C++ Note: risk checked 126.33 C++ Note: risk1 checked 260.899 81.7736 101.847 C++ Note: risk2 checked 778.474 246.131 318.199 C++ Note: df101 -464.18 -464.18 -464.18 C++ Note: df102 -47.7167 -15.934 -19.8545 C++ Note: df103 -870.336 -126.985 -214.851 C++ Note: df104 0.0432318 0.0270369 0.180906 C++ Note: Checking Deviance 700.36 C++ Note: df105 0.0548256 0.125479 0.0924107 C++ Note: df106 9.72783 29.1314 23.379 C++ Note: df100 5513 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.0376245 0.00657003 0.0557566 C++ Note: sums checked 1078.56 1013.1 1098.33 C++ Note: derivs checked 2206.61 2012.57 1909.31 C++ Note: second derivs checked 6573.57 5934.53 5569.82 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1078.56 1013.1 1098.33 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1078.56 1013.1 1098.33 C++ Note: risk checked 112.808 C++ Note: risk1 checked 231.02 75.6258 69.025 C++ Note: risk2 checked 688.083 225.739 201.15 C++ Note: df101 -462.759 -462.759 -462.759 C++ Note: df102 -14.5654 -5.21187 0.637868 C++ Note: df103 -770.184 -99.8931 -90.8891 C++ Note: df104 0.0376245 0.00657003 0.0557566 C++ Note: Checking Deviance 697.518 C++ Note: df105 0.0189115 0.0521745 -0.00701809 C++ Note: df106 31.7712 88.7894 -725.478 C++ Note: df100 6691 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df100 6738 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df101 -462.7591 -462.7591 -462.7591 C++ Note: df102 -14.56536 -5.211874 0.6378678 C++ Note: df103 -770.1842 -99.89313 -90.88914 C++ Note: df104 0.03762453 0.006570034 0.05575656 C++ Note: Checking Deviance 697.5182 C++ Note: df105 0.01891153 0.0521745 -0.007018085 C++ Note: df106 31.7712 88.78939 -725.4781 C++ Note: df101 -462.759 -462.759 -462.759 C++ Note: df102 -14.5654 -5.21187 0.637868 C++ Note: df103 -770.184 -99.8931 -90.8891 C++ Note: df104 0.0376245 0.00657003 0.0557566 C++ Note: Checking Deviance 697.518 C++ Note: df105 0.0189115 0.0521745 -0.00701809 C++ Note: df106 31.7712 88.7894 -725.478 C++ Note: df501 -462.7591 C++ Note: df504 0.03762453 0.006570034 0.05575656 Warning: model covariate order changed C++ Note: START_POIS_GUESS C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Term checked 0 1 2 C++ Note: df99,30,Starting C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: starting subterms 3 in guess 0 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: derivs checked 2662.16 2662.16 1673.67 C++ Note: second derivs checked 8088.51 8088.51 4753.83 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 116.849 C++ Note: risk1 checked 89.4661 89.4661 56.218 C++ Note: risk2 checked 271.789 271.789 159.656 C++ Note: df101 -463.51 -463.51 -463.51 C++ Note: df102 -12.0037 -12.0037 -0.410377 C++ Note: df103 -143.316 -143.316 -59.8747 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 699.02 C++ Note: df105 0.0837566 0.0837566 0.00685392 C++ Note: df106 38.614 38.614 1129.47 C++ Note: Starting Halves C++ Note: df501 -463.5098 C++ Note: df504 0.1 0.1 0.01 C++ Note: values checked 0.0371826 0.0371826 0.00485956 C++ Note: sums checked 1077.58 1077.58 1007.96 C++ Note: derivs checked 2203.71 2203.71 1649.45 C++ Note: second derivs checked 6563.98 6563.98 4670.84 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1077.58 1077.58 1007.96 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1077.58 1077.58 1007.96 C++ Note: risk checked 106.323 C++ Note: risk1 checked 74.0612 74.0612 55.4045 C++ Note: risk2 checked 220.567 220.567 156.868 C++ Note: df101 -462.873 -462.873 -462.873 C++ Note: df102 0.991755 0.991755 5.79074 C++ Note: df103 -89.711 -89.711 -50.9916 C++ Note: df104 0.0371826 0.0371826 0.00485956 C++ Note: Checking Deviance 697.746 C++ Note: df105 -0.011055 -0.011055 -0.113563 C++ Note: df106 -466.721 -466.721 -79.9334 C++ Note: df100 2431 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df100 2480 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df101 -462.873 -462.873 -462.873 C++ Note: df102 0.991755 0.991755 5.790736 C++ Note: df103 -89.71102 -89.71102 -50.99157 C++ Note: df104 0.03718258 0.03718258 0.004859558 C++ Note: Checking Deviance 697.7461 C++ Note: df105 -0.011055 -0.011055 -0.1135626 C++ Note: df106 -466.7211 -466.7211 -79.93336 C++ Note: df101 -462.873 -462.873 -462.873 C++ Note: df102 0.991755 0.991755 5.79074 C++ Note: df103 -89.711 -89.711 -50.9916 C++ Note: df104 0.0371826 0.0371826 0.00485956 C++ Note: Checking Deviance 697.746 C++ Note: df105 -0.011055 -0.011055 -0.113563 C++ Note: df106 -466.721 -466.721 -79.9334 C++ Note: ending guess 0 C++ Note: df501 -462.873 C++ Note: df504 0.03718258 0.03718258 0.004859558 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.03718258 0.03718258 0.004859558, -462.873<-- Best Guess C++ Note: starting subterms 3 in best guess 0 C++ Note: values checked 0.0371826 0.0371826 0.00485956 C++ Note: sums checked 1077.58 1077.58 1007.96 C++ Note: derivs checked 2203.71 2203.71 1649.45 C++ Note: second derivs checked 6563.98 6563.98 4670.84 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1077.58 1077.58 1007.96 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1077.58 1077.58 1007.96 C++ Note: risk checked 106.323 C++ Note: risk1 checked 74.0612 74.0612 55.4045 C++ Note: risk2 checked 220.567 220.567 156.868 C++ Note: Made Risk Side Lists C++ Note: df101 -462.873 -462.873 -462.873 C++ Note: df102 0.991755 0.991755 5.79074 C++ Note: df103 -89.711 -89.711 -50.9916 C++ Note: df104 0.0371826 0.0371826 0.00485956 C++ Note: Checking Deviance 697.746 C++ Note: df105 -0.011055 -0.011055 -0.113563 C++ Note: df106 -466.721 -466.721 -79.9334 C++ Note: Starting Halves C++ Note: df501 -462.873 C++ Note: df504 0.03718258 0.03718258 0.004859558 C++ Note: values checked 0.0454738 0.0454738 0.0900315 C++ Note: sums checked 1096.08 1096.08 1167.18 C++ Note: derivs checked 2258.88 2258.88 2112.17 C++ Note: second derivs checked 6746.42 6746.42 6283.7 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1096.08 1096.08 1167.18 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1096.08 1096.08 1167.18 C++ Note: risk checked 112.914 C++ Note: risk1 checked 75.9152 75.9152 70.9449 C++ Note: risk2 checked 226.697 226.697 211.036 C++ Note: df101 -462.685 -462.685 -462.685 C++ Note: df102 -4.74661 -4.74661 -1.37928 C++ Note: df103 -100.025 -100.025 -101.757 C++ Note: df104 0.0454738 0.0454738 0.0900315 C++ Note: Checking Deviance 697.37 C++ Note: df105 0.0474545 0.0474545 0.0135546 C++ Note: df106 97.4769 97.4769 335.454 C++ Note: df100 5350 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df100 5398 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df101 -462.6849 -462.6849 -462.6849 C++ Note: df102 -4.746612 -4.746612 -1.37928 C++ Note: df103 -100.0246 -100.0246 -101.757 C++ Note: df104 0.04547382 0.04547382 0.09003152 C++ Note: Checking Deviance 697.3697 C++ Note: df105 0.04745446 0.04745446 0.01355464 C++ Note: df106 97.47686 97.47686 335.4539 C++ Note: df101 -462.685 -462.685 -462.685 C++ Note: df102 -4.74661 -4.74661 -1.37928 C++ Note: df103 -100.025 -100.025 -101.757 C++ Note: df104 0.0454738 0.0454738 0.0900315 C++ Note: Checking Deviance 697.37 C++ Note: df105 0.0474545 0.0474545 0.0135546 C++ Note: df106 97.4769 97.4769 335.454 C++ Note: df501 -462.6849 C++ Note: df504 0.04547382 0.04547382 0.09003152 Warning: model covariate order changed C++ Note: START_POIS_GUESS C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Term checked 0 1 2 C++ Note: df99,30,Starting C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: starting subterms 3 in guess 0 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 4021.52 C++ Note: df101 -4464.36 -4464.36 -4464.36 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 8700.72 C++ Note: Starting Halves C++ Note: df501 -4464.359 C++ Note: df504 0.1 0.1 0.01 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 4021.52 C++ Note: df101 -4464.36 -4464.36 -4464.36 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 8700.72 C++ Note: df100 1072 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 4021.52 C++ Note: df101 -4464.36 -4464.36 -4464.36 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 8700.72 C++ Note: df100 1569 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 4021.52 C++ Note: df101 -4464.36 -4464.36 -4464.36 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 8700.72 C++ Note: df100 2122 3 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 4021.52 C++ Note: df101 -4464.36 -4464.36 -4464.36 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 8700.72 C++ Note: df100 2620 4 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 4021.52 C++ Note: df101 -4464.36 -4464.36 -4464.36 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 8700.72 C++ Note: df100 3118 5 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df100 3165 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df101 -4464.359 -4464.359 -4464.359 C++ Note: df104 0.1 0.1 0.01 C++ Note: df101 -4464.36 -4464.36 -4464.36 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 8700.72 C++ Note: ending guess 0 C++ Note: df501 -4464.359 C++ Note: df504 0.1 0.1 0.01 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.1 0.1 0.01, -4464.359<-- Best Guess C++ Note: starting subterms 3 in best guess 0 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 4021.52 C++ Note: Made Risk Side Lists C++ Note: df101 -4464.36 -4464.36 -4464.36 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 8700.72 C++ Note: Starting Halves C++ Note: df501 -4464.359 C++ Note: df504 0.1 0.1 0.01 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 4021.52 C++ Note: df101 -4464.36 -4464.36 -4464.36 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 8700.72 C++ Note: df100 4476 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 4021.52 C++ Note: df101 -4464.36 -4464.36 -4464.36 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 8700.72 C++ Note: df100 4976 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 4021.52 C++ Note: df101 -4464.36 -4464.36 -4464.36 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 8700.72 C++ Note: df100 5508 3 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 4021.52 C++ Note: df101 -4464.36 -4464.36 -4464.36 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 8700.72 C++ Note: df100 6007 4 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 4021.52 C++ Note: df101 -4464.36 -4464.36 -4464.36 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 8700.72 C++ Note: df100 6507 5 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df100 6554 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df101 -4464.359 -4464.359 -4464.359 C++ Note: df104 0.1 0.1 0.01 C++ Note: df101 -4464.36 -4464.36 -4464.36 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 8700.72 C++ Note: df501 -4464.359 C++ Note: df504 0.1 0.1 0.01 Warning: model covariate order changed C++ Note: START_POIS_GUESS C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Term checked 0 1 2 C++ Note: df99,30,Starting C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: starting subterms 3 in guess 0 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 3476.32 C++ Note: df101 -3870.25 -3870.25 -3870.25 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 7512.5 C++ Note: Starting Halves C++ Note: df501 -3870.252 C++ Note: df504 0.1 0.1 0.01 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 3476.32 C++ Note: df101 -3870.25 -3870.25 -3870.25 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 7512.5 C++ Note: df100 1065 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 3476.32 C++ Note: df101 -3870.25 -3870.25 -3870.25 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 7512.5 C++ Note: df100 1562 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 3476.32 C++ Note: df101 -3870.25 -3870.25 -3870.25 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 7512.5 C++ Note: df100 2102 3 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 3476.32 C++ Note: df101 -3870.25 -3870.25 -3870.25 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 7512.5 C++ Note: df100 2598 4 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 3476.32 C++ Note: df101 -3870.25 -3870.25 -3870.25 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 7512.5 C++ Note: df100 3092 5 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df100 3139 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df101 -3870.252 -3870.252 -3870.252 C++ Note: df104 0.1 0.1 0.01 C++ Note: df101 -3870.25 -3870.25 -3870.25 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 7512.5 C++ Note: ending guess 0 C++ Note: df501 -3870.252 C++ Note: df504 0.1 0.1 0.01 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, 0.1 0.1 0.01, -3870.252<-- Best Guess C++ Note: starting subterms 3 in best guess 0 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 3476.32 C++ Note: Made Risk Side Lists C++ Note: df101 -3870.25 -3870.25 -3870.25 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 7512.5 C++ Note: Starting Halves C++ Note: df501 -3870.252 C++ Note: df504 0.1 0.1 0.01 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 3476.32 C++ Note: df101 -3870.25 -3870.25 -3870.25 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 7512.5 C++ Note: df100 4447 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 3476.32 C++ Note: df101 -3870.25 -3870.25 -3870.25 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 7512.5 C++ Note: df100 4944 2 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 3476.32 C++ Note: df101 -3870.25 -3870.25 -3870.25 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 7512.5 C++ Note: df100 5487 3 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 3476.32 C++ Note: df101 -3870.25 -3870.25 -3870.25 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 7512.5 C++ Note: df100 5985 4 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 3476.32 C++ Note: df101 -3870.25 -3870.25 -3870.25 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 7512.5 C++ Note: df100 6485 5 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df100 6531 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df101 -3870.252 -3870.252 -3870.252 C++ Note: df104 0.1 0.1 0.01 C++ Note: df101 -3870.25 -3870.25 -3870.25 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 7512.5 C++ Note: df501 -3870.252 C++ Note: df504 0.1 0.1 0.01 Warning: model covariate order changed C++ Note: START_POIS_GUESS C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Term checked 0 1 2 C++ Note: df99,30,Starting C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: starting subterms 3 in guess 0 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: derivs checked 2662.16 2662.16 1673.67 C++ Note: second derivs checked 8088.51 8088.51 4753.83 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 4021.52 C++ Note: risk1 checked 8990.66 3623.84 2047.21 C++ Note: risk2 checked 27640.9 11337.7 5801.4 C++ Note: df101 -4464.36 -4464.36 -4464.36 C++ Note: df102 -9823.7 -3961.6 -2223.36 C++ Note: df103 -30965.7 -12538.3 -6371.77 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 8700.72 C++ Note: df105 0.317244 0.315959 0.34894 C++ Note: df106 0.454448 1.12691 2.00793 C++ Note: Starting Halves C++ Note: df501 -4464.359 C++ Note: df504 0.1 0.1 0.01 C++ Note: values checked -0.137933 -0.136969 -0.251705 C++ Note: sums checked 775.553 776.836 702.601 C++ Note: derivs checked 1328.21 1331.8 841.86 C++ Note: second derivs checked 3721.09 3732.5 2034.61 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 775.553 776.836 702.601 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 775.553 776.836 702.601 C++ Note: risk checked 1943.25 C++ Note: risk1 checked 3180.78 914.006 655.882 C++ Note: risk2 checked 8802.59 2426.63 1587.74 C++ Note: df101 -2228.98 -2228.98 -2228.98 C++ Note: df102 -3323.52 -952.67 -688.275 C++ Note: df103 -9864.88 -2573.61 -1698.13 C++ Note: df104 -0.137933 -0.136969 -0.251705 C++ Note: Checking Deviance 4229.97 C++ Note: df105 0.336904 0.370169 0.405314 C++ Note: df106 0.67067 2.33972 3.23851 C++ Note: df100 2157 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df100 2204 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df101 -2228.983 -2228.983 -2228.983 C++ Note: df102 -3323.517 -952.6701 -688.2751 C++ Note: df103 -9864.881 -2573.61 -1698.127 C++ Note: df104 -0.1379333 -0.1369691 -0.2517047 C++ Note: Checking Deviance 4229.966 C++ Note: df105 0.336904 0.3701688 0.4053143 C++ Note: df106 0.6706698 2.339722 3.238506 C++ Note: df101 -2228.98 -2228.98 -2228.98 C++ Note: df102 -3323.52 -952.67 -688.275 C++ Note: df103 -9864.88 -2573.61 -1698.13 C++ Note: df104 -0.137933 -0.136969 -0.251705 C++ Note: Checking Deviance 4229.97 C++ Note: df105 0.336904 0.370169 0.405314 C++ Note: df106 0.67067 2.33972 3.23851 C++ Note: ending guess 0 C++ Note: df501 -2228.983 C++ Note: df504 -0.1379333 -0.1369691 -0.2517047 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1379333 -0.1369691 -0.2517047, -2228.983<-- Best Guess C++ Note: starting subterms 3 in best guess 0 C++ Note: values checked -0.137933 -0.136969 -0.251705 C++ Note: sums checked 775.553 776.836 702.601 C++ Note: derivs checked 1328.21 1331.8 841.86 C++ Note: second derivs checked 3721.09 3732.5 2034.61 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 775.553 776.836 702.601 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 775.553 776.836 702.601 C++ Note: risk checked 1943.25 C++ Note: risk1 checked 3180.78 914.006 655.882 C++ Note: risk2 checked 8802.59 2426.63 1587.74 C++ Note: Made Risk Side Lists C++ Note: df101 -2228.98 -2228.98 -2228.98 C++ Note: df102 -3323.52 -952.67 -688.275 C++ Note: df103 -9864.88 -2573.61 -1698.13 C++ Note: df104 -0.137933 -0.136969 -0.251705 C++ Note: Checking Deviance 4229.97 C++ Note: df105 0.336904 0.370169 0.405314 C++ Note: df106 0.67067 2.33972 3.23851 C++ Note: Starting Halves C++ Note: df501 -2228.983 C++ Note: df504 -0.1379333 -0.1369691 -0.2517047 C++ Note: values checked -0.390611 -0.414596 -0.55569 C++ Note: sums checked 532.749 516.988 517.87 C++ Note: derivs checked 677.199 637.561 432.04 C++ Note: second derivs checked 1711.97 1594.9 857.807 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 532.749 516.988 517.87 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 532.749 516.988 517.87 C++ Note: risk checked 1160.77 C++ Note: risk1 checked 1287.6 260.671 231.783 C++ Note: risk2 checked 3158.62 543.41 460.892 C++ Note: df101 -1440.04 -1440.04 -1440.04 C++ Note: df102 -1204.6 -248.036 -228.728 C++ Note: df103 -3543.56 -513.003 -465.909 C++ Note: df104 -0.390611 -0.414596 -0.55569 C++ Note: Checking Deviance 2652.09 C++ Note: df105 0.339942 0.483498 0.49093 C++ Note: df106 1.19545 5.80578 6.29587 C++ Note: df100 4825 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df100 4872 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df101 -1440.044 -1440.044 -1440.044 C++ Note: df102 -1204.604 -248.0364 -228.7284 C++ Note: df103 -3543.556 -513.0035 -465.9085 C++ Note: df104 -0.3906113 -0.4145957 -0.5556904 C++ Note: Checking Deviance 2652.088 C++ Note: df105 0.3399422 0.4834984 0.4909299 C++ Note: df106 1.19545 5.805777 6.295868 C++ Note: df101 -1440.04 -1440.04 -1440.04 C++ Note: df102 -1204.6 -248.036 -228.728 C++ Note: df103 -3543.56 -513.003 -465.909 C++ Note: df104 -0.390611 -0.414596 -0.55569 C++ Note: Checking Deviance 2652.09 C++ Note: df105 0.339942 0.483498 0.49093 C++ Note: df106 1.19545 5.80578 6.29587 C++ Note: df501 -1440.044 C++ Note: df504 -0.3906113 -0.4145957 -0.5556904 Warning: model covariate order changed C++ Note: START_POIS_GUESS C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: Term checked 0 1 2 C++ Note: df99,30,Starting C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: starting subterms 3 in guess 0 C++ Note: values checked 0.1 0.1 0.01 C++ Note: sums checked 1229.91 1229.91 1016.5 C++ Note: derivs checked 2662.16 2662.16 1673.67 C++ Note: second derivs checked 8088.51 8088.51 4753.83 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 1229.91 1229.91 1016.5 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 1229.91 1229.91 1016.5 C++ Note: risk checked 3476.32 C++ Note: risk1 checked 2662.16 2662.16 1673.67 C++ Note: risk2 checked 8088.51 8088.51 4753.83 C++ Note: df101 -3870.25 -3870.25 -3870.25 C++ Note: df102 -2892.89 -2892.89 -1814.56 C++ Note: df103 -8899.28 -8899.28 -5219.6 C++ Note: df104 0.1 0.1 0.01 C++ Note: Checking Deviance 7512.5 C++ Note: df105 0.32507 0.32507 0.347644 C++ Note: df106 1.33785 1.33785 2.13288 C++ Note: Starting Halves C++ Note: df501 -3870.252 C++ Note: df504 0.1 0.1 0.01 C++ Note: values checked -0.143803 -0.143803 -0.250733 C++ Note: sums checked 767.821 767.821 703.42 C++ Note: derivs checked 1306.57 1306.57 843.84 C++ Note: second derivs checked 3652.41 3652.41 2040.66 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 767.821 767.821 703.42 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 767.821 767.821 703.42 C++ Note: risk checked 2239.06 C++ Note: risk1 checked 1306.57 1306.57 843.84 C++ Note: risk2 checked 3652.41 3652.41 2040.66 C++ Note: df101 -2541.39 -2541.39 -2541.39 C++ Note: df102 -1381.02 -1381.02 -889.259 C++ Note: df103 -3933.71 -3933.71 -2190.79 C++ Note: df104 -0.143803 -0.143803 -0.250733 C++ Note: Checking Deviance 4854.78 C++ Note: df105 0.351073 0.351073 0.405908 C++ Note: df106 1.84023 1.84023 2.85787 C++ Note: df100 2098 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df100 2146 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df101 -2541.39 -2541.39 -2541.39 C++ Note: df102 -1381.017 -1381.017 -889.2586 C++ Note: df103 -3933.706 -3933.706 -2190.791 C++ Note: df104 -0.1438028 -0.1438028 -0.2507329 C++ Note: Checking Deviance 4854.78 C++ Note: df105 0.3510728 0.3510728 0.4059076 C++ Note: df106 1.84023 1.84023 2.857875 C++ Note: df101 -2541.39 -2541.39 -2541.39 C++ Note: df102 -1381.02 -1381.02 -889.259 C++ Note: df103 -3933.71 -3933.71 -2190.79 C++ Note: df104 -0.143803 -0.143803 -0.250733 C++ Note: Checking Deviance 4854.78 C++ Note: df105 0.351073 0.351073 0.405908 C++ Note: df106 1.84023 1.84023 2.85787 C++ Note: ending guess 0 C++ Note: df501 -2541.39 C++ Note: df504 -0.1438028 -0.1438028 -0.2507329 C++ Note: Refreshing matrices after all guesses C++ Note: Guess Results Guess number, parameter values, Log-Likelihood 0, -0.1438028 -0.1438028 -0.2507329, -2541.39<-- Best Guess C++ Note: starting subterms 3 in best guess 0 C++ Note: values checked -0.143803 -0.143803 -0.250733 C++ Note: sums checked 767.821 767.821 703.42 C++ Note: derivs checked 1306.57 1306.57 843.84 C++ Note: second derivs checked 3652.41 3652.41 2040.66 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 767.821 767.821 703.42 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 767.821 767.821 703.42 C++ Note: risk checked 2239.06 C++ Note: risk1 checked 1306.57 1306.57 843.84 C++ Note: risk2 checked 3652.41 3652.41 2040.66 C++ Note: Made Risk Side Lists C++ Note: df101 -2541.39 -2541.39 -2541.39 C++ Note: df102 -1381.02 -1381.02 -889.259 C++ Note: df103 -3933.71 -3933.71 -2190.79 C++ Note: df104 -0.143803 -0.143803 -0.250733 C++ Note: Checking Deviance 4854.78 C++ Note: df105 0.351073 0.351073 0.405908 C++ Note: df106 1.84023 1.84023 2.85787 C++ Note: Starting Halves C++ Note: df501 -2541.39 C++ Note: df504 -0.1438028 -0.1438028 -0.2507329 C++ Note: values checked -0.407107 -0.407107 -0.555164 C++ Note: sums checked 521.807 521.807 518.098 C++ Note: derivs checked 649.637 649.637 432.492 C++ Note: second derivs checked 1630.48 1630.48 858.997 C++ Note: dose checked 1000 1000 1000 C++ Note: non-dose checked 521.807 521.807 518.098 C++ Note: LIN_non-dose checked 1000 1000 1000 C++ Note: PLIN_non-dose checked 1000 1000 1000 C++ Note: LOGLIN_non-dose checked 521.807 521.807 518.098 C++ Note: risk checked 1561.71 C++ Note: risk1 checked 649.637 649.637 432.492 C++ Note: risk2 checked 1630.48 1630.48 858.997 C++ Note: df101 -1840.51 -1840.51 -1840.51 C++ Note: df102 -652.83 -652.83 -432.167 C++ Note: df103 -1682.85 -1682.85 -882.861 C++ Note: df104 -0.407107 -0.407107 -0.555164 C++ Note: Checking Deviance 3453.02 C++ Note: df105 0.387933 0.387933 0.489507 C++ Note: df106 2.81927 2.81927 4.25879 C++ Note: df100 4709 1 1 0,Update_calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df100 4756 0 0 0,Update_Calc C++ Note: Current Time, Tue Feb 13 22:47:19 2024 C++ Note: df101 -1840.508 -1840.508 -1840.508 C++ Note: df102 -652.8304 -652.8304 -432.1668 C++ Note: df103 -1682.845 -1682.845 -882.8612 C++ Note: df104 -0.4071074 -0.4071074 -0.5551637 C++ Note: Checking Deviance 3453.016 C++ Note: df105 0.3879325 0.3879325 0.4895071 C++ Note: df106 2.819274 2.819274 4.258791 C++ Note: df101 -1840.51 -1840.51 -1840.51 C++ Note: df102 -652.83 -652.83 -432.167 C++ Note: df103 -1682.85 -1682.85 -882.861 C++ Note: df104 -0.407107 -0.407107 -0.555164 C++ Note: Checking Deviance 3453.02 C++ Note: df105 0.387933 0.387933 0.489507 C++ Note: df106 2.81927 2.81927 4.25879 C++ Note: df501 -1840.508 C++ Note: df504 -0.4071074 -0.4071074 -0.5551637 [ FAIL 0 | WARN 0 | SKIP 0 | PASS 1095 ] > > proc.time() user system elapsed 24.92 2.68 23.20